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Recent Advances In The Design Of Novel Polymer Nanoagents For Cancer Theranostics
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Book Synopsis Recent Advances in the Design of Novel Polymer Nanoagents for Cancer Theranostics by : Hanlin Ou
Download or read book Recent Advances in the Design of Novel Polymer Nanoagents for Cancer Theranostics written by Hanlin Ou and published by Frontiers Media SA. This book was released on 2023-12-14 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Theranostic Materials by : Ashutosh Tiwari
Download or read book Advanced Theranostic Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2015-06-30 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Book Synopsis Novel Theranostics Based on Hybrid Nanoparticles for Early Cancer Detection and Treatment by : Siyue Li
Download or read book Novel Theranostics Based on Hybrid Nanoparticles for Early Cancer Detection and Treatment written by Siyue Li and published by . This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Novel Theranostics Based on Hybrid Nanoparticles for Early Cancer Detection and Treatment" by Siyue, Li, 李思越, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Nanoscience and nanotechnology have advanced rapidly in recent years and have made a profound impact in the medical field. Nanoparticles have attracted great attention for their potential as diagnostic and/or therapeutic tools in oncology owing to their unique properties. Theranostics are nanodevices with diagnostic, therapeutic and possibly treatment-monitoring functions for treating cancers. Different noble metal nanoparticles can provide the basic unit for theranostics. Suitably designed and developed noble metal nanoparticle-based theranostics will have multiple functions. In this project, the design, fabrication and performance of novel multifunctional nanodevices for cancer detection and treatment were investigated. The foundation of this project was laid by investigating different types of hybrid nanoparticles for novel theranostics. Different approaches were developed for fabricating core-shell structured hybrid nanoparticles. Highly branched gold and gold-silver bimetallic nanoparticles were firstly made. pH-sensitive folic acid-chitosan (CS-FA) conjugate was then introduced on these nanoparticles to form hybrid nanoparticles with a metal core (Au@CS-FA and Au-Ag@CS-FA). Poly(lactide-co-glycolide) (PLGA) and chitosan (CS) micro- or nanoparticles were also produced to serve as the polymer core for forming hybrid particles with a gold or gold-silver nanoshell (PLGA@Au, CS@Au and PLGA@Ag-Au). Furthermore, Fe3O4@Au nanoparticles having both magnetic and plasmonic properties were investigated. Thermo-sensitive poly(N-isopropylacrylamide) (pNIPAm) polymer or pH-sensitive CS-FA was then coated on Fe3O4@Au nanoparticles, forming new hybrid nanoparticles. The formation mechanisms of nanoparticles and hybrid nanoparticles were studied. Raman reporters (Rhodamine B or 4-mercaptobenzoic acid) and anti-cancer drugs (paclitaxel or 5-fluorouracil) were loaded into the polymer core or shell of hybrid nanoparticles to form multifunctional nanodevices. While the noble metal unit in the nanodevices provided high light-scattering enhancement for achieving photothermal effect, the polymer component encapsulated Raman reporter molecules and put them close to the metal nanoparticles for generating high surface enhanced Raman scattering (SERS) signals. These nanodevices could also serve as excellent drug carriers, and the stimulus-triggered release of incorporated drug was studied. It was shown in this project that the conjugation of targeting ligand (e.g. folic acid) or antibody (e.g. anti-HER2 monoclonal antibody) on hybrid nanoparticles had formed novel theranostics which allowed selective detection, continuous imaging of intracellular behavior and killing of targeted cancer cells. These theranostics could be taken up by specific cancer cells through receptor-mediated endocytosis and internalized into cytoplasma of the cell. These theranostics as stable SERS-active tags and imaging agents for HeLa cells, SK-BR-3 cancer cells or MCF-7 cancer cells were demonstrated. The targeting ability and intracellular uptake of these theranostics were studied. The photothermal effect of the theranostics was investigated using different laser irradiation powers. The anti-cancer treatment could be significantly improved by the synergistic effects of chemo- and photothermal therapy when these theranostics were also tasked as the carrier of anti-cancer drugs. Therefore, combining plasmonic metal
Book Synopsis Metal Nanoparticles in Pharma by : Mahendra Rai, Ph.D
Download or read book Metal Nanoparticles in Pharma written by Mahendra Rai, Ph.D and published by Springer. This book was released on 2017-11-14 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely dedicated to the biomedical applications of metal nanoparticles, this book covers the different toxicity problems found in healthcare situations and also provides comprehensive info on the use of metal nanoparticles in treating various diseases. Metal Nanoparticles in Pharma is the first edited volume to set up the discussion for a clinical setting and to target a pharmaceutical audience of academic and industry-based researchers.
Book Synopsis Cancer Nanotheranostics by : P. Gopinath
Download or read book Cancer Nanotheranostics written by P. Gopinath and published by Springer. This book was released on 2015-03-10 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief provides a clear insight of the recent advances in the field of cancer theranostics with special emphasis upon nano scale carrier molecules (polymeric, protein and lipid based) and imaging agents (organic and inorganic).
Book Synopsis Design and Applications of Theranostic Nanomedicines by : Somasree Ray
Download or read book Design and Applications of Theranostic Nanomedicines written by Somasree Ray and published by Woodhead Publishing. This book was released on 2022-09-10 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design and Applications of Theranostic Nanomedicines reviews the composition and design of various nanomedicines for theranostic applications, helping readers to make informed decisions when exploring novel treatments for disease. This book introduces readers to theranostic nanostructures as nanomedicines, beginning with a balanced look at the associated challenges, costs and benefits. The next section goes on to detail a range of different theranostic nanomedicines and their design, from nanodispersions and nanogels to exosomes and polymeric micelles. A variety of applications is covered, including in the treatment of pulmonary diseases, neurological disorders, cancers and more. The book also takes a look at the toxicological implications of nanotheranostics, an important aspect of any therapy or treatment. Design and Applications of Theranostic Nanomedicines provides a snapshot of the state-of-the-art, and will be of use to materials scientists, biomedical engineers and pharmaceutical scientists with an interest in nanotechnology and theranostics. Explores the challenges, costs, benefits and toxicological implications of nanotheranostics Reviews a range of nanomedicines and their design, including liposomes, nanohydrogels, nanocochleate and more Details a variety of applications, such as in drug delivery, neurological disorders, cardiovascular diseases and so on
Book Synopsis Nanomedicine for Deep-Tissue High-Resolution Bio-Imaging and Non-Invasive Therapy by : Michael Ming-Yuan Wei
Download or read book Nanomedicine for Deep-Tissue High-Resolution Bio-Imaging and Non-Invasive Therapy written by Michael Ming-Yuan Wei and published by Frontiers Media SA. This book was released on 2020-11-12 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr Ming-Yuan Wei currently holds a pending U.S. Patent Application entitled “Systems and Methods for High-Resolution Imaging”. All other Guest Editors have no other competing interests to declare with regards to the Topic subject.
Book Synopsis Advanced Bioactive Nanomaterials for Diagnosis and Treatment of Major Chronic Diseases by : Fan Huang
Download or read book Advanced Bioactive Nanomaterials for Diagnosis and Treatment of Major Chronic Diseases written by Fan Huang and published by Frontiers Media SA. This book was released on 2023-10-30 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cutaneous Melanoma written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications by : Abdel Salam Hamdy Makhlouf
Download or read book Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications written by Abdel Salam Hamdy Makhlouf and published by Woodhead Publishing. This book was released on 2018-10-24 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume Two: Advanced Nanocarriers for Therapeutics discusses, in detail, the recent trends in designing dual and multi-responsive polymers and nanoparticles for safe drug delivery. Chapters cover dual-responsive polymeric nanocarriers for drug delivery and their different stimuli, multi-responsive polymeric nanocarriers, and the therapeutic applications of stimuli-responsive polymers. With an emphasis on advanced medical applications and synergistic operational and technological methodologies for the improvement of polymers systems for the production of stimuli-responsive polymers, this book is essential reading for materials scientists and researchers working in the drug delivery and pharmaceutical industries. As innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery, users will find this to be a timely resource. Focusses on the most advanced technologies, recent evaluation methods, technical aspects, and advanced synthesis techniques stimuli-responsive polymers Examines advanced medical applications of stimuli responsive polymers Analyzes synergistic operational and technological methodologies for the improvement of polymer systems for the production of stimuli-responsive polymers in drug delivery
Book Synopsis Particulate Technology for Delivery of Therapeutics by : Sougata Jana
Download or read book Particulate Technology for Delivery of Therapeutics written by Sougata Jana and published by Springer. This book was released on 2017-10-09 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose related potential toxicity of drug molecules, which in turn lead to increased potential compliance. Various types of organic, inorganic and polymer particles are currently being investigated. These are attracting the attention of the research workers in the field of drug delivery science and technology. This book covers polymersomes, inorganic- organic composites, gold nanoparticles biopolymer and synthetic polymer particles etc.All aspects of drug delivery in relation to each technology have been described including these advances, Easy to read and understand the content of each chapter Rich in up-to-date information regarding their application.
Book Synopsis Carbon Nanotubes for Biomedical Applications by : Rüdiger Klingeler
Download or read book Carbon Nanotubes for Biomedical Applications written by Rüdiger Klingeler and published by Springer Science & Business Media. This book was released on 2011-02-09 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.
Book Synopsis Nanostructured Polymer Composites for Biomedical Applications by : Sarat Kumar Swain
Download or read book Nanostructured Polymer Composites for Biomedical Applications written by Sarat Kumar Swain and published by Elsevier. This book was released on 2019-06-15 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment. Summarizes the most recent strategies to develop nanostructured polymer composite biomaterials for biomedicine Outlines the major preparation and characterization techniques for a range of polymer nanocomposites used in biomedicine Explores the design of new types of nanostructured polymer composites for applications in drug delivery, tissue engineering, gene therapy and bone replacement
Download or read book Nanooncology written by Gil Gonçalves and published by Springer. This book was released on 2018-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.
Book Synopsis Nanoparticles in Medicine by : Ashutosh Kumar Shukla
Download or read book Nanoparticles in Medicine written by Ashutosh Kumar Shukla and published by Springer Nature. This book was released on 2019-08-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div
Download or read book Nanocosmetics written by Arun Nanda and published by Elsevier. This book was released on 2020-05-06 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is key to the design and manufacture of the new generation of cosmetics. Nanotechnology can enhance the performance and properties of cosmetics, including colour, transparency, solubility, texture, and durability. Sunscreen products, such as UV nano-filters, nano-TiO2 and nano-ZnO particles, can offer an advantage over their traditional counterparts due to their broad UV-protection and non-cutaneous side effects. For perfumes, nano-droplets can be found in cosmetic products including Eau de Toilette and Eau de Parfum. Nanomaterials can also be used in cosmetics as transdermal drug delivery systems. By using smart nanocontainers, active compounds such as vitamins, antioxidants, nutrients, and anti-inflammatory, anti-infective agents, can be delivered effectively. These smart nanocontainers are typically related with the smart releasing property for their embedded active substances. These smart releases could be obtained by using the smart coatings as their outer nano-shells. These nano-shells could prevent the direct contact between these active agents and the adjacent local environments. Nanocosmetics: Fundamentals, Applications and Toxicity explores the formulation design concepts and emerging applications of nanocosmetics. The book also focuses on the mitigation or prevention of their potential nanotoxicity, potential global regulatory challenges, and the technical challenges of mass implementation. It is an important reference source for materials scientists and pharmaceutical scientists looking to further their understanding of how nanotechnology is being used for the new generation of cosmetics. Outlines the major fabrication and formulation design concepts of nanoscale products for cosmetic applications Explores how nanomaterials can safely be used for various applications in cosmetic products Assesses the major challenges of using nanomaterials for cosmetic applications on a large scale
Book Synopsis Regenerative Medicine and Stem Cell Biology by : Nagwa El-Badri
Download or read book Regenerative Medicine and Stem Cell Biology written by Nagwa El-Badri and published by Springer Nature. This book was released on 2020-11-27 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.
