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Author :
Publisher :
ISBN 13 : 9789240698345
Total Pages : pages
Book Rating : 4.6/5 (983 download)
Download or read book Managing Epidemics written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hervé Emonard
Publisher : Frontiers Media SA
ISBN 13 : 2889450244
Total Pages : 131 pages
Book Rating : 4.8/5 (894 download)
Download or read book Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies written by Hervé Emonard and published by Frontiers Media SA. This book was released on 2016-11-22 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically acting on ECM homeostasis. Matricellular receptors mediate numerous signalings from the extracellular environment to cell nucleus and drive main biological functions that are cell growth, survival and migration. Numerous data from the last decade evidence that matricellular receptors are biosensors that allow to a tumor cell answering to microenvironmental variations, and in this sense they are important contributors to tumor cell malignancy. Matricellular receptors represent thus valuable targets for the development of original anti-cancer strategies. Original reports, bibliographic reviews or hypotheses are welcome to improve the basic knowledge of matricellular receptor properties, their spatio-temporal regulation, the dynamic formation of complex receptors and the impact of such interactions on the invasive properties of tumor cells. Biological, biophysical and pharmacological, as well as in silico contributions will be appreciated.
Author : Robert Salas
Publisher : Career Press
ISBN 13 : 9781601633422
Total Pages : 0 pages
Book Rating : 4.6/5 (334 download)
Download or read book Unidentified written by Robert Salas and published by Career Press. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1969 the U.S. Air Force issued a statement that read' "No UFO reported, investigated and evaluated by the Air Force was ever an indication of threat to our national security." This statement is patently false. It has been proven untrue by the testimony of many military officers and airmen and documentation of incidents involving UFOs and nuclear weapons, testimonies of which the U.S. Air Force was fully aware. Unidentified details many of these testimonies, some for the first time. As partial justification for its position, the Air Force cites a University of Colorado study that was contracted and paid for by federal funds. Unidentified reveals how this study was actually just another part of the plan to cover up the reality of the UFO phenomenon. For the first time, Unidentified publishes evidence that the investigators for the Colorado study knew about the UFO-related missile shutdown incidents but did not investigate them or include them in their final report.
Author : Laurence Gardner
Publisher : HarperCollins UK
ISBN 13 : 000714296X
Total Pages : 466 pages
Book Rating : 4.0/5 (71 download)
Download or read book Lost Secrets of the Sacred Ark written by Laurence Gardner and published by HarperCollins UK. This book was released on 2004 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ark of the Covenant is the source of one of the deepest mysteries of the Western world. Laurence Gardner has accessed Rosicrucian archives to reveal where the Ark is, what it is and how this lost secret of the distant past has led to the phenomenal new science of space-time manipulation.
Author : Clifford E. Stone
Publisher : S.P.I. Books
ISBN 13 : 9781561719723
Total Pages : 0 pages
Book Rating : 4.7/5 (197 download)
Download or read book UFOs are Real written by Clifford E. Stone and published by S.P.I. Books. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lars A. Akslen
Publisher :
ISBN 13 : 9783030989514
Total Pages : 0 pages
Book Rating : 4.9/5 (895 download)
Download or read book Biomarkers of the Tumor Microenvironment written by Lars A. Akslen and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Author : Buzz Aldrin
Publisher : Open Road Media
ISBN 13 : 1480421537
Total Pages : 802 pages
Book Rating : 4.4/5 (84 download)
Download or read book Encounter with Tiber written by Buzz Aldrin and published by Open Road Media. This book was released on 2013-05-28 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Apollo 11 astronaut and the Nebula Award–nominated author of Directive 51 present a novel that “conveys the wonder and promise of space” (Publishers Weekly). Born the year of the Moon landing, Chris Terence spends his life fighting to return humanity to that pinnacle. An engineering student with dreams of spaceflight, he finds upon graduation that the United States no longer has need for astronauts. Years of bureaucratic meddling have reduced the space program to a shell of itself, and it will take the greatest scientific find in history to send humanity skyward once more. After years battling budget hawks, Chris finally gets his chance to walk on the Moon. While there, he finds evidence of an ancient alien civilization, the Tiberians, who visited Earth’s satellite eight thousand years before. Understanding what happened to those long-forgotten travelers will define the lives of Chris and his son, as they fight against all odds to unlock the secrets of the universe. “The collaboration of the first man to pilot a moon lander (Aldrin) with a major voice in contemporary science fiction (Barnes) has produced a fascinating chronicle of man’s first encounter with alien intelligence” (Booklist).
Author : Charles-Joël Menkès
Publisher : Elsevier Masson
ISBN 13 : 9782294013737
Total Pages : 164 pages
Book Rating : 4.0/5 (137 download)
Download or read book La polyarthrite rhumatoïde de l'adulte written by Charles-Joël Menkès and published by Elsevier Masson. This book was released on 2004 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: La polyarthrite rhumatoïde est le rhumatisme articulaire inflammatoire chronique le plus fréquent. Elle touche en France environ 600 000 personnes. C'est une maladie très invalidante dont les formes sont diverses et d'évolution variable. Le diagnostic à un stade précoce est déterminant car il permet de débuter rapidement le traitement et prévient, ou limite, ainsi les destructions articulaires. Dans cet ouvrage pratique et didactique, le praticien trouvera toutes les informations indispensables sur la clinique, le diagnostic, les examens complémentaires, l'évolution, les traitements envisageables et l'éducation des patients. Une grande partie de l'ouvrage est consacrée à la manière d'adapter les traitements à chaque patient et au suivi de celui-ci. Cet ouvrage permet au médecin, interlocuteur privilégié du patient atteint de polyarthrite rhumatoïde, d'améliorer la vie de celui-ci au quotidien. La polyarthrite rhumatoïde étant à la fois une maladie systémique et un ensemble de maladies locales, le médecin généraliste pourra se situer au sein du dispositif de prise en charge et du travail d'équipe dans lequel le rhumatologue, le chirurgien, le rééducateur, le psychologue et lui-même ont tous leur importance.
Author : Lars A. Akslen
Publisher : Springer
ISBN 13 : 331939147X
Total Pages : 537 pages
Book Rating : 4.3/5 (193 download)
Download or read book Biomarkers of the Tumor Microenvironment written by Lars A. Akslen and published by Springer. This book was released on 2017-08-02 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.
Author : Andrea Sritharan-Mancilla Serra
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (144 download)
Download or read book Polyarthrite rhumatoïde written by Andrea Sritharan-Mancilla Serra and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cette thèse examine en profondeur la polyarthrite rhumatoïde (PR), une maladie auto-immune complexe. La première partie se concentre sur la définition précise de la PR, explorant ses caractéristiques épidémiologiques. Elle détaille également les signes cliniques observés à différentes étapes de la maladie, mettant en évidence l'évolution de la symptomatologie et l'importance du diagnostic précoce pour une intervention efficace. Cette première partie aborde également les moyens de diagnostic utilisés pour identifier la PR, en examinant les outils cliniques, biologiques et d'imagerie qui contribuent à une détection précise de la maladie. Elle souligne l'importance d'une approche multidisciplinaire pour garantir une gestion optimale de cette pathologie complexe. La seconde partie de la thèse se concentre sur les aspects étiologiques et physiopathologiques de la PR. Elle explore les facteurs génétiques, immunologiques et environnementaux qui contribuent au développement de la maladie, ainsi que les mécanismes biologiques sous-jacents responsables de la destruction articulaire et des manifestations systémiques de la PR. En outre, cette partie examine en détail les options thérapeutiques actuelles pour la PR, mettant en lumière les progrès récents dans le développement de nouvelles molécules thérapeutiques ciblées. Cette thèse offre une analyse approfondie de la PR, allant de sa définition et de son diagnostic à ses étiologies, sa physiopathologie et sa prise en charge médicamenteuse. Elle souligne l'importance d'une approche holistique et intégrée pour améliorer la compréhension et la gestion de cette maladie auto-immune complexe, avec l'objectif ultime d'améliorer la qualité de vie des patients.
Author : Bernard Combe (médecin).)
Publisher :
ISBN 13 : 9782915968286
Total Pages : 37 pages
Book Rating : 4.9/5 (682 download)
Download or read book Mise au point sur les biothérapies en monothérapie dans la polyarthrite rhumatoïde written by Bernard Combe (médecin).) and published by . This book was released on 2010 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt:
