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Author :
Publisher :
ISBN 13 : 9788360391334
Total Pages : 139 pages
Book Rating : 4.3/5 (913 download)
Download or read book Rationally Designed Peptide Based Functional Biomaterials written by and published by . This book was released on 2014 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mustafa O. Guler
Publisher : Royal Society of Chemistry
ISBN 13 : 1839161159
Total Pages : 413 pages
Book Rating : 4.8/5 (391 download)
Download or read book Peptide-based Biomaterials written by Mustafa O. Guler and published by Royal Society of Chemistry. This book was released on 2020-11-18 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.
Author : Anwar Sunna
Publisher : Springer
ISBN 13 : 3319660950
Total Pages : 309 pages
Book Rating : 4.3/5 (196 download)
Download or read book Peptides and Peptide-based Biomaterials and their Biomedical Applications written by Anwar Sunna and published by Springer. This book was released on 2017-10-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.
Author : Sotirios Koutsopoulos
Publisher : Woodhead Publishing
ISBN 13 : 0081007426
Total Pages : 655 pages
Book Rating : 4.0/5 (81 download)
Download or read book Peptide Applications in Biomedicine, Biotechnology and Bioengineering written by Sotirios Koutsopoulos and published by Woodhead Publishing. This book was released on 2017-11-16 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides
Author : Mohamed A. Elsawy
Publisher : Springer Nature
ISBN 13 : 3031293606
Total Pages : 556 pages
Book Rating : 4.0/5 (312 download)
Download or read book Peptide Bionanomaterials written by Mohamed A. Elsawy and published by Springer Nature. This book was released on 2023-08-28 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular self-assembly has been exploited by nature for developing the higher functional macromolecular structures of both the genome and proteome. Inspired by nature, there has been a surge of research, in the last two decades, for the molecular engineering of peptide-based self-assembling nanostructures, adopting the bottom-up design approach. This book gives the reader an overview on the design rules for de novo self-assembling peptide and reviews the diverse range of bioinspired peptide nanostructures such as β-sheet and β-hairpin, α-helical and coiled coil, self-assembling short peptides and peptidomimetics, collagen-based and elastin-like peptides, silk peptides, peptide amphiphiles, peptides co-polymers and others. The book also covers the wide variety of responsive and functional biomaterials that have been innovated based on those nanostructures for various applications ranging from tissue engineering, therapeutics and drug delivery to antimicrobial nanomaterials and biosensors. Finally, the book also discusses the peptide bionanomaterials global market and the future of the emerging industry. Chapter “Characterization of Peptide-Based Nanomaterials” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Suvrat Chowdhary
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)
Download or read book Rational Design of Polyfluorinated Et Enzyme-degradable Peptide-based Biomaterials written by Suvrat Chowdhary and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Helena S. Azevedo
Publisher : Woodhead Publishing
ISBN 13 : 0081020120
Total Pages : 614 pages
Book Rating : 4.0/5 (81 download)
Download or read book Self-assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-17 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. Explores both theoretical and practical aspects of self-assembly in biomaterials Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials Examines the use of dynamic self-assembling biomaterials
Author : Karthikan Rajagopal
Publisher :
ISBN 13 : 9781109861860
Total Pages : 235 pages
Book Rating : 4.8/5 (618 download)
Download or read book Rational Peptide Design for Functional Materials Via Molecular Self-assembly written by Karthikan Rajagopal and published by . This book was released on 2007 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significance of peptide design in the context of self-assembly and its relationship to the nanostructure was studied by designing a series of peptides derived from MAX1. Evolving from these studies is an understanding of the relationship between molecular level peptide structure and the nanoscale supra-molecular morphology. Based on this, it has been shown that alternate morphologies distinct from those observed with the gel forming peptides, such as non-twisting laminates or tube-like structures can be constructed. Lastly, it is shown that within amphiphilic beta-hairpin peptides, the turn sequence can be used as a design element to control the stiffness of the hydrogel which is an important property from an application point of view. These studies demonstrate that rationally designed peptides are robust building blocks to construct functional materials via molecular self-assembly.
Author : Timothy Deming
Publisher : Springer Science & Business Media
ISBN 13 : 3642271391
Total Pages : 184 pages
Book Rating : 4.6/5 (422 download)
Download or read book Peptide-Based Materials written by Timothy Deming and published by Springer Science & Business Media. This book was released on 2012-01-10 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-
Author : Hongzhou Huang
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (894 download)
Download or read book Self-assembling Peptide Hydrogel written by Hongzhou Huang and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Rational design of peptide molecules to undergo spontaneous organization as a higher-ordered supramolecular structure is an attractive and fast-growing field for developing new functional biomaterials. Hydrogel, with its high water content and three-dimensional architecture, is formed by a self-assembling peptide and has great potential for broad biomedical applications. The key challenge in controlling the functional properties of final biomaterials can be met by designing the peptide primary structure carefully at the beginning and developing a comprehensive understanding of peptide self-assembly pathways. In this study, we first designed a Ca2 responsive peptide (eD2) using identified functional native domains from a spider flagelliform silk protein and the Ca2 binding domain of lipase Lip A from Serratia marcescens. Instead of directly linking the two peptide sequences, we rationally inserted the ion-binding motif into the silk structure sequence and made the new peptide inherit the physical characteristics of both model sequences and assemble into nanofibers when triggered by Ca2. Next, we introduced the amphiphilic property to the eD2 peptide by conjugating its N-terminus with a strong hydrophobic sequence from a trans-membrane segment of human muscle L-type calcium channel. This self-assembly peptide, called h9e, was responsive to Ca2+, solution pH, and selected proteins for hydrogel formation. Interestingly, the turning segment GSII of h9e was considered to play a critical role in construction of the finial matrix. This hypothesis was further demonstrated by exploiting a series of amphiphilic diblock model peptides with different conformational flexibility. The kinetic rate of peptide assembly was suggested as one of the key influences for peptide supramolecular assembly morphology. To better understand the peptide self-assembly process during hydrogel formation, the conformational, morphological, and mechanical properties of h9e molecules in different dimethylsulfoxide/H2O solutions were monitored by 1D and 2D proton nuclear magnetic resonance (NMR), electron microscopy, and a rheometer. The h9e peptide hydrogel formed with Ca2+ and albumin exhibited superior physiological and specific injectable properties, which provides a more realistic tool for 3D cell culture and drug delivery. This study generates new knowledge and contributes to the field by leading to a better understanding the self-assembly hydrogel formation and designing peptides with unique properties for biomedical applications such as cell culture, drug delivery, and tissue engineering.
Author : Wilhelm T.S. Huck
Publisher : Springer Science & Business Media
ISBN 13 : 0387256563
Total Pages : 249 pages
Book Rating : 4.3/5 (872 download)
Download or read book Nanoscale Assembly written by Wilhelm T.S. Huck and published by Springer Science & Business Media. This book was released on 2006-07-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has received tremendous interest over the last decade, not only from the scientific community but also from a business perspective and from the general public. Although nanotechnology is still at the largely unexplored frontier of science, it has the potential for extremely exciting technological innovations that will have an enormous impact on areas as diverse as information technology, medicine, energy supply and probably many others. The miniturization of devices and structures will impact the speed of devices and information storage capacity. More importantly, though, nanotechnology should lead to completely new functional devices as nanostructures have fundamentally different physical properties that are governed by quantum effects. When nanometer sized features are fabricated in materials that are currently used in electronic, magnetic, and optical applications, quantum behavior will lead to a set of unprecedented properties. The interactions of nanostructures with biological materials are largely unexplored. Future work in this direction should yield enabling technologies that allows the study and direct manipulation of biological processes at the (sub) cellular level.
Author : Rafael Vargas-Bernal
Publisher : BoD – Books on Demand
ISBN 13 : 1838803378
Total Pages : 150 pages
Book Rating : 4.8/5 (388 download)
Download or read book Hybrid Nanomaterials written by Rafael Vargas-Bernal and published by BoD – Books on Demand. This book was released on 2020-06-10 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two of the hottest research topics today are hybrid nanomaterials and flexible electronics. As such, this book covers both topics with chapters written by experts from across the globe. Chapters address hybrid nanomaterials, electronic transport in black phosphorus, three-dimensional nanocarbon hybrids, hybrid ion exchangers, pressure-sensitive adhesives for flexible electronics, simulation and modeling of transistors, smart manufacturing technologies, and inorganic semiconductors.
Author : John Howl
Publisher : Springer Science & Business Media
ISBN 13 : 1592598773
Total Pages : 263 pages
Book Rating : 4.5/5 (925 download)
Download or read book Peptide Synthesis and Applications written by John Howl and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.
Author : Kevin Healy
Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)
Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Author : Lia Rimondini
Publisher : Frontiers Media SA
ISBN 13 : 2889666875
Total Pages : 176 pages
Book Rating : 4.8/5 (896 download)
Download or read book Rational Design and Characterization of Innovative Multifunctional Biomimetic Materials written by Lia Rimondini and published by Frontiers Media SA. This book was released on 2021-04-13 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gang Wei
Publisher : Woodhead Publishing
ISBN 13 : 0081028512
Total Pages : 504 pages
Book Rating : 4.0/5 (81 download)
Download or read book Artificial Protein and Peptide Nanofibers written by Gang Wei and published by Woodhead Publishing. This book was released on 2020-07-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed. This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine. Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibers Discusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesis Provides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering
Author : Namita Roy Choudhury
Publisher : Royal Society of Chemistry
ISBN 13 : 1839161027
Total Pages : 297 pages
Book Rating : 4.8/5 (391 download)
Download or read book Biomimetic Protein Based Elastomers written by Namita Roy Choudhury and published by Royal Society of Chemistry. This book was released on 2022-04-20 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elastomeric proteins are ubiquitous in nature, where they have evolved precise structures and properties that are necessary to perform specific biological roles and functions. This book emphasizes the impact of amino acid sequence on modulating protein structure, properties, and function. Examples include conformational ensemble dynamics, environmental responsiveness, self-assembly, physico-mechanical properties, morphology, and properties tailored for biomedical applications. This foundational framework is not only critical to advance scientific understanding and knowledge on elastomeric proteins but also enables the conceptualization, rational design, and development of biosynthetic elastomers and their analogous polypeptides for a variety of applications. Edited and contributed by pioneering researchers in the field, the book provides a timely overview of the materials, along with the synthesis techniques, the unique characteristics of elastomeric proteins, and biomedical and industrial applications. The book will provide a reference for graduate students and researchers interested in designing biomimetic proteins tailored for various functions.
