Radiopharmaceuticals Using Radioactive Compounds in Pharmaceutics and Medicine

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Author :
Publisher : Ellis Horwood
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis Radiopharmaceuticals Using Radioactive Compounds in Pharmaceutics and Medicine by : A. E. Theobald

Download or read book Radiopharmaceuticals Using Radioactive Compounds in Pharmaceutics and Medicine written by A. E. Theobald and published by Ellis Horwood. This book was released on 1989 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radiopharmaceuticls

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Publisher : Halsted Press
ISBN 13 : 9780470215104
Total Pages : 184 pages
Book Rating : 4.2/5 (151 download)

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Book Synopsis Radiopharmaceuticls by : A. E. Theobald

Download or read book Radiopharmaceuticls written by A. E. Theobald and published by Halsted Press. This book was released on 1989 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Nuclear Pharmacy

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Publisher : Springer
ISBN 13 : 3319575805
Total Pages : 428 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Therapeutic Nuclear Medicine

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Publisher : Springer
ISBN 13 : 3540367195
Total Pages : 922 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Therapeutic Nuclear Medicine by : Richard P. Baum

Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

Safety and efficacy of radiopharmaceuticals

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Publisher : Springer Science & Business Media
ISBN 13 : 9400967535
Total Pages : 392 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Safety and efficacy of radiopharmaceuticals by : Knud Kristensen

Download or read book Safety and efficacy of radiopharmaceuticals written by Knud Kristensen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safety and efficacy of radiopharmaceuticals are elements of great importance in nuclear medicine. Since the first meeting in 1965 in Oak Ridge with the title Radiopharmaceuticals tremendous developments have taken place. In 1965 the whole technetium-99m area was just in its very beginning. Safety and efficacy of the non-radioactive pharmaceuticals have attracted great attention during the last 10 years and so have similar aspects of radiopharmaceuticals during the later years. Regulatory agencies are extending their work also to the preparation of radiopharmaceuticals at hospitals and to requirements for registration of radiopharmaceuticals. In a fast developing field there might be tendencies to confrontation between interests and there have certainly been some tendencies to put undue restrictions on the use of radio pharmaceuticals due to the lack of understanding between the industry and the regulatory authorities and between regulatory authorities and hospitals. Much of this may have been due to lack of information and certainly is due to the lack of fundamental scientific knowledge in many radiopharmaceutical aspects. A fast and safe introduction of new radio pharmaceuticals and the proper handling of these requires a lot of development work, but also an understanding of how general principles from the non-radioactive drug field may be sensibly transformed into the radiopharmaceutical area. It may even require compromises between requirements for safety in different areas such as radiation protection and pharmaceutical aspects.

Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine

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Publisher : American Pharmacists Association (APhA)
ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine by : Richard J. Kowalsky

Download or read book Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine written by Richard J. Kowalsky and published by American Pharmacists Association (APhA). This book was released on 2004 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 2nd edition," is an essential reference for nuclear pharmacy practitioners, nuclear medicine technologists, and nuclear medicine physicians. It will also be useful as a textbook in programs that educate these practitioners. The first 12 chapters cover radioactive decay, radiation detection and measurement, radiation protection and risk, radiation safety, radiation biology, licensing and regulatory controls, radionuclide production, radiopharmaceutical chemistry, radiopharmaceuticals for positron emission tomography (PET), the nuclear pharmacy, and quality control. Four of these chapters are written by contributing authors. Together the 12 chapters, all written by nuclear pharmacy practitioners, present the information needed for a pharmacist to become an authorized nuclear pharmacist. The remaining 11 chapters cover the diagnostic and therapeutic use of radiopharmaceuticals. Chapters on specific body systems (brain, thyroid, heart, lung, liver, spleen, gastrointestinal tract, kidney, and bone) are followed by chapters on total body procedures, monoclonal antibodies, in vivo function studies, and therapeutic radiopharmaceuticals. Key Features *Updates its predecessor, Radiopharmaceuticals in Nuclear Medicine Practice, to include new material in areas such as radiation biology, radiopharmaceuticals used in PET, and therapeutic radiopharmaceuticals. *Features expanded coverage of nuclear medicine applications of radiopharmaceuticals useful for nuclear pharmacy practitioners. *Some 150 tables and nearly 450 figures enrich and illustrate the text, and each chapter is referenced to the primary literature. About the Authors: Richard J. Kowalsky, PharmD, BCNP, FAPhA, is Associate Professor of Pharmacy, School of Pharmacy, and Associate Professor of Radiology, Department of Radiology, University of North Carolina at Chapel Hill. He is Director of the Nuclear Pharmacy at UNC Hospitals, where he has practiced for 32 years. Steven W. Falen, MD, PhD, is former Director of Positron Emission Tomography and Assistant Professor of Radiology and Biomedical Engineering, Department of Radiology, University of North Carolina at Chapel Hill. He is now Director of Nuclear Medicine and PET Services, Riverside Regional Medical Center, Newport News, Virginia.

Technetium-99m Pharmaceuticals

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Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

Radiopharmaceuticals

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Publisher : Routledge
ISBN 13 : 1351419900
Total Pages : 460 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Radiopharmaceuticals by : AdrainD. Nunn

Download or read book Radiopharmaceuticals written by AdrainD. Nunn and published by Routledge. This book was released on 2018-04-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely resource compares single-photon emission tomography (SPECT), used mainly withTechnetium and iodine for routine clinical examinations, and positron emission tomography(PET) , employing short-lived radionuclides of carbon, oxygen, nitrogen, and fluorine in researchinvestigations.Presenting the logic behind why one approach is better than another in various circumstances,Radio pharmaceuticals details the use of radiolabelled substrates in measuring the effect of diseaseand drugs on regional metabolism and receptor concentration/occupancy .. . discusses factorsaffecting the selective retention of small metal complexes by various tissues .. . analyzes the interactionof small exogenous metal complexes with enzymes in vivo and the critical role of stereochemistry. . . explores the use of radio labelled compounds in the study of neuroactive compounds,neurotransmitters, enzyme inhibitors, and substrates in vivo .. . covers the design and pharmacologyof radiolabelled drugs as probes of site of action , selectivity and specificity, and pharmacokineticsin vivo .. . and more.Extensively referenced with over l 050 bibliographic citations, Radiopharmaceuticals is a state-ofthe-art guide for pharmacists; organic, medicinal , and radiopharmaceutical chemists; pharmacokineticists;nuclear medicine physicians and technologists; neurochemists; and governmentregulatory personnel .

Analysis of Pharmaceuticals by Capillary Electrophoresis

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Publisher : Springer Science & Business Media
ISBN 13 : 3322850110
Total Pages : 300 pages
Book Rating : 4.3/5 (228 download)

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Book Synopsis Analysis of Pharmaceuticals by Capillary Electrophoresis by : Kevin D. Altria

Download or read book Analysis of Pharmaceuticals by Capillary Electrophoresis written by Kevin D. Altria and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieser erste Titel einer ganzen Serie von anwendungsbezogenen Handbüchern zur Kapillarelektrophorese beschäftigt sich mit der Analytik von pharmazeutischen Substanzen. Dabei werden verschiedene Techniken praxisnah erläutert. Jeder, der im Labor - ob wissenschaftlich oder praxisnah - mit der Analyse von oft chiralen Pharmazeutika konfrontiert ist, wird viele Hinweise und Tips für seine Arbeit finden.USP: Einzige Monographie zur Analyse von Pharmazeutika mit CE This book describes the current state of the art for the analysis of pharmaceuticals by capillary electrophoresis and contains several hundred references to specific applications and methods. The main purpose of the book is to present the application possibilities of CE an therefore tabulated application data are provided. Chapters of the book are devoted to providing details of individual application areas such as chiral analysis, determination of drug related impurities, determination of drug counter-ions, drug residue monitoring and main component assay. An introductory chapter provides theoretical background to CE an related techniques. A chapter is dedicated to capillary electrochromatography which highlights the importance this technique currently possesses. Successful regulatory acceptance of CE methods is also described. A comprehensive chapter covers method validation aspects. Other chapters include discrete areas such as the use of non-aqueous solvents, forensic applications of CE, the application of experimental designs, determination of drugs in biofluids, and the analysis of vitamins by CE.

Handbook of Radiopharmaceuticals

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119500540
Total Pages : 768 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Handbook of Radiopharmaceuticals by : Michael R. Kilbourn

Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Fundamentals of Nuclear Pharmacy

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Publisher : Springer Science & Business Media
ISBN 13 : 1475740271
Total Pages : 318 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new edition of a book is warranted when the book is successful and there are many new developments in the related discipline. Both have occurred for this book during the past 7 years since its second edition. The growth and development in nuclear pharmacy and radiopharmaceutical chemistry along with the continued success of the book have convinced us to update the book; hence this third edition. This book is a ramification of my nuclear pharmacy courses offered to pharmacy students specializing in nuclear pharmacy, nuclear medicine resi dents, and nuclear medicine technology students. The book is written in an integrated form from the basic concept of atomic structure to the practical clinical uses of radiopharmaceuticals. It serves both as a textbook on nu clear pharmacy for pharmacy students and nuclear medicine technologists, and as a useful reference book for many professionals related to nuclear medicine, such as nuclear medicine physicians and radiologists. The book contains 12 chapters. Each chapter is written as comprehen sively as possible based on my personal experience and understanding. At the end of each chapter, a section of pertinent questions and problems and so me suggested reading materials are included. I have made justifiably many additions and deletions as weIl as some reorganization in this edition. Chapter 3 is entirely dedicated to instru ments for radiation detection and measurement, including brief description of gas detectors, gamma-detecting instruments, and tomographic scanners.

The Handbook of Radiopharmaceuticals

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Publisher : Springer
ISBN 13 : 1475704143
Total Pages : 242 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis The Handbook of Radiopharmaceuticals by : Azuwuike Owunwanne

Download or read book The Handbook of Radiopharmaceuticals written by Azuwuike Owunwanne and published by Springer. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: One Radiobiopharmaceutics.- 1 Preparation of radiopharmaceuticals.- Production of radionuclides.- Synthesis of the non-radioactive compound.- Reaction of the radionuclide with the non-radioactive compound.- References.- 2 Ideal characteristics of radiopharmaceuticals.- Availability and cost.- Preparation.- Biologic behavior.- Radionuclidic characteristics.- Hematology.- 3 Quality control of radiopharmaceuticals.- Biologic tests.- Physicochemical tests.- References.- 4 Design of radiopharmaceuticals.- Radionuclide.- Chemistry.- Biology.- Human studies.- Registration.- References.- 5 The fate of.

Medical Imaging for Health Professionals

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Publisher : John Wiley & Sons
ISBN 13 : 1119120292
Total Pages : 528 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Medical Imaging for Health Professionals by : Raymond M. Reilly

Download or read book Medical Imaging for Health Professionals written by Raymond M. Reilly and published by John Wiley & Sons. This book was released on 2019-01-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the most common imaging technologies and their diagnostic applications so that pharmacists and other health professionals, as well as imaging researchers, can understand and interpret medical imaging science This book guides pharmacists and other health professionals and researchers to understand and interpret medical imaging. Divided into two sections, it covers both fundamental principles and clinical applications. It describes the most common imaging technologies and their use to diagnose diseases. In addition, the authors introduce the emerging role of molecular imaging including PET in the diagnosis of cancer and to assess the effectiveness of cancer treatments. The book features many illustrations and discusses many patient case examples. Medical Imaging for Health Professionals: Technologies and Clinical Applications offers in-depth chapters explaining the basic principles of: X-Ray, CT, and Mammography Technology; Nuclear Medicine Imaging Technology; Radionuclide Production and Radiopharmaceuticals; Magnetic Resonance Imaging (MRI) Technology; and Ultrasound Imaging Technology. It also provides chapters written by expert radiologists in well-explained terminology discussing clinical applications including: Cardiac Imaging; Lung Imaging; Breast Imaging; Endocrine Gland Imaging; Abdominal Imaging; Genitourinary Tract Imaging; Imaging of the Head, Neck, Spine and Brain; Musculoskeletal Imaging; and Molecular Imaging with Positron Emission Tomography (PET). Teaches pharmacists, health professionals, and researchers the basics of medical imaging technology Introduces all of the customary imaging tools—X-ray, CT, ultrasound, MRI, SPECT, and PET—and describes their diagnostic applications Explains how molecular imaging aids in cancer diagnosis and in assessing the effectiveness of cancer treatments Includes many case examples of imaging applications for diagnosing common diseases Medical Imaging for Health Professionals: Technologies and Clinical Applications is an important resource for pharmacists, nurses, physiotherapists, respiratory therapists, occupational therapists, radiological or nuclear medicine technologists, health physicists, radiotherapists, as well as researchers in the imaging field.

Progress in Radiopharmacy

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Publisher : Springer Science & Business Media
ISBN 13 : 9400942974
Total Pages : 615 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Progress in Radiopharmacy by : P.H. Cox

Download or read book Progress in Radiopharmacy written by P.H. Cox and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this volume are based upon presentations made to the Second European Symposium on Radiopharmacy and Radiopharmaceuticals which was held in St. Catharine's College Cambridge in March 1985. This meeting was organized by the Radiopharmacy Group of the British Nuclear Medicine Society under the auspices of the European Joint Committee on Radio pharmaceuticals of the ENMS / SNME. The Joint Committee acknowledges the special effort which was made by the local organizers to prepare this meeting the quality of which is undoubtedly reflected in the proceedings. The wide ranging aspects of Radiopharmacy are reflected in this volume which not only deals with specialized topics, such as aerosols and biodistribution studies, but which also deals with the professional aspects of Radiopharmacy Practice. We are of the opinion that this book complements earlier publications to give an ongoing picture of the practice of Radiopharmacy and the state of the art in Europe. As well as acknowledging the contribution of the British Radiopharmacists I would also mention the support of my co chairman Prof. Dr M.G. Woldring, the members of the Joint Committee and last but not least Mrs. M. Busker, who prepared the camera ready copy. P.H. Cox Co-ordinating Chairman European Joint Committee on Radiopharmaceuticals Rotterdam XI CCNrRIBUTORS Anderson, M.L. - Pharnacy department, London Hospital London, UK. Angelberger, P. - Osterreichische Forschungszentrum Seibersdorf GmbH, Wien, Austria. Claessens, R.A.M.J. - Department of Nuclear Medicine, St. Radboud Ziekenhuis, Nijrnegen, The Netherlands.

Radiopharmaceuticals

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839696591
Total Pages : 228 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Radiopharmaceuticals by : Farid A. Badria

Download or read book Radiopharmaceuticals written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2022-06-15 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy discusses the importance of radiopharmaceuticals and their environmental, pharmaceutical, diagnostic, therapeutic, and research applications. Chapters address such topics as the fundamentals of radiopharmaceutical chemistry and preparation, fabrication, materials manipulation, and characterization of radiopharmaceuticals, applications of radiopharmaceuticals in preclinical studies, radiopharmaceuticals in modern cancer therapy, and new trends in preparation, biodistribution, and pharmacokinetics of radiopharmaceuticals in diagnosis and research.

Radiopharmaceuticals in Nuclear Medicine Practice

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Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiopharmaceuticals in Nuclear Medicine Practice by : Richard J. Kowalsky

Download or read book Radiopharmaceuticals in Nuclear Medicine Practice written by Richard J. Kowalsky and published by . This book was released on 1987 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: