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Author : International Atomic Energy Agency
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolism written by International Atomic Energy Agency and published by . This book was released on 1965 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Agence internationale de l'énergie atomique
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (11 download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolism written by Agence internationale de l'énergie atomique and published by . This book was released on 1965 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : International Atomic Energy Agency
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (926 download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolism written by International Atomic Energy Agency and published by . This book was released on 1965 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (911 download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolism written by and published by . This book was released on 1965 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert R. Wolfe
Publisher : John Wiley & Sons
ISBN 13 : 9780471462095
Total Pages : 494 pages
Book Rating : 4.4/5 (62 download)
Download or read book Isotope Tracers in Metabolic Research written by Robert R. Wolfe and published by John Wiley & Sons. This book was released on 2004-10-18 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes: All-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis A completely updated categorized list of over 750 references Major advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques The latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics New coverage of mathematical modeling Expanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.
Author : Julie McBride Frantz
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.:/5 (816 download)
Download or read book The Use of Radioactive Isotopes in Studying Protein Metabolism in Humans written by Julie McBride Frantz and published by . This book was released on 1948 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert R. Wolfe
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)
Download or read book Tracers in Metabolic Research written by Robert R. Wolfe and published by . This book was released on 1984 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods for studying metabolism. Determination of substrate kinetics. Constant isotope infusion technique. Determination of substrate kinetics. Bolus-injection technique. Determination of substrate oxidation. Bicarbonate kinetics and natural enrichment. Priming the pool. Nonsteady state kinetics. Selection of sites for infusing isotope andj drawing samples. Specific application. Glucose metabolism. Specific application. Urea. Specific application. Fat meltabolism. Amino acids. Whole-body protein turnover. Total body water. Clinical application of stable isotopes. Analytical methods. Instrumentation. Mass spectrometry. Selected ion monitoring. Preparation of samples. Chromatography. Determination of specific radioactivity. Collection of CO2. Isotope ratio mass spectrometry techniques. Gas chromatography-mass spectrometry methods. In vivo approaches. Isotopic tracers. Advantages of stable isotopes. Biological effects. Enzymatic effects. Definition of terms. Influence of uptake on calculation of rate of appearance. Influence of pool size and complexity. Net movement of tracer and tracee. Clearance. Stable versus radioisotopes. Single-pool analysis. Bicarbonate recovery. Natural abundance of 13C. Practical consideration of performing recovery studies. Determining NaH13 CO3 infusion rate. Determining VCO2. Theory of priming dose. Priming secondary pools. Steele equation. In vivo assessment of steele equation. Glucose. Effective volume of distribution. Urea. Arterial versus central venous infusion.
Author : International Atomic Energy Agency
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.E/5 ( download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolism written by International Atomic Energy Agency and published by . This book was released on 1965 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Organismo Internacional de Energía Atómica
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (432 download)
Download or read book Radioisotope Techniques in the Study of Protein Metabolitum written by Organismo Internacional de Energía Atómica and published by . This book was released on 1965 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture
Publisher :
ISBN 13 : 9789201154705
Total Pages : 29 pages
Book Rating : 4.1/5 (547 download)
Download or read book Isotope Techniques for Studying Animal Protein Production from Non-protein Nitrogen written by Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture and published by . This book was released on 1970 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R.M. Lambrecht
Publisher : Springer
ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.:/5 (42 download)
Download or read book Tracer Kinetics and Physiologic Modeling written by R.M. Lambrecht and published by Springer. This book was released on 1983 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: These lectures were prepared by the authors for Seminars to be held on June 6, 1983, in St.Louis, Missouri, under the spon sorship of the Radiopharmaceutical Science Council of the So ciety of Nuclear Medicine . All manuscript? were refereed . Tracer kinetics and the modeling of physiological and bio chemical processes in vivo are the focus of a contemporary di rection in biochemical research. Recent advances in instrumen tation (especially positron emission tomography and digital autoradiography) and parallel developments in the production of short-lived radionuclides and rapid synthetic chemistry to pre pare tracers that probe metabolism, flow, receptor-ligand kinetics, etc., are responsible for new scientific frontiers. These developments, coupled with biomathematics and computer science, make it possible to quantitatively evaluate tracer kinetic models in animals and man. (The choice of animal models in radiotracer design and tracer kinetics is the subject of a book edited by R.M.Lambrecht and W.C.Eckleman in press at Sprin ger Verlag.) Tracer kinetics and physiological modeling is truly multi disciplinary, as evidenced by the intellectual diversity and international representation observable in the list of contri butors . The lectures outline and attempt to show the transition from the theoretical description to the practical application of modeling for understanding normal and pathological processes .
Author : Ji-Xin Cheng
Publisher : Elsevier
ISBN 13 : 0323903371
Total Pages : 612 pages
Book Rating : 4.3/5 (239 download)
Download or read book Stimulated Raman Scattering Microscopy written by Ji-Xin Cheng and published by Elsevier. This book was released on 2021-12-04 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stimulated Raman Scattering Microscopy: Techniques and Applications describes innovations in instrumentation, data science, chemical probe development, and various applications enabled by a state-of-the-art stimulated Raman scattering (SRS) microscope. Beginning by introducing the history of SRS, this book is composed of seven parts in depth including instrumentation strategies that have pushed the physical limits of SRS microscopy, vibrational probes (which increased the SRS imaging functionality), data science methods, and recent efforts in miniaturization. This rapidly growing field needs a comprehensive resource that brings together the current knowledge on the topic, and this book does just that. Researchers who need to know the requirements for all aspects of the instrumentation as well as the requirements of different imaging applications (such as different types of biological tissue) will benefit enormously from the examples of successful demonstrations of SRS imaging in the book. Led by Editor-in-Chief Ji-Xin Cheng, a pioneer in coherent Raman scattering microscopy, the editorial team has brought together various experts on each aspect of SRS imaging from around the world to provide an authoritative guide to this increasingly important imaging technique. This book is a comprehensive reference for researchers, faculty, postdoctoral researchers, and engineers. - Includes every aspect from theoretic reviews of SRS spectroscopy to innovations in instrumentation and current applications of SRS microscopy - Provides copious visual elements that illustrate key information, such as SRS images of various biological samples and instrument diagrams and schematics - Edited by leading experts of SRS microscopy, with each chapter written by experts in their given topics
Author : Stephen Welle
Publisher : Springer Science & Business Media
ISBN 13 : 9780387987507
Total Pages : 306 pages
Book Rating : 4.9/5 (875 download)
Download or read book Human Protein Metabolism written by Stephen Welle and published by Springer Science & Business Media. This book was released on 1999-07-30 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: A succinct review of hundreds of studies on the regulation of protein mass and protein turnover in the human body. The book summarizes the biochemistry of protein synthesis and breakdown, and explains the methods that are used to examine protein metabolism in humans, together with their limitations. Chapters review the effects of nutrition, hormones, metabolic substrates, and physical activity, while various topics of clinical interest include cancer, diabetes, tissue injury, pregnancy, renal disease, muscular dystrophies, and other conditions. Normal values are presented for turnover of proteins in the whole body and individual organs, and for turnover of many individual proteins. This is thus a valuable resource for physiologists, nutritionists, and clinicians interested in the regulation of body protein stores in health and disease. For scientists primarily interested in the basic aspects of protein metabolism, it shows how the basic knowledge is being applied to the study of humans.
Author : Mrinal K. Dewanjee
Publisher : Springer Science & Business Media
ISBN 13 : 1461535085
Total Pages : 627 pages
Book Rating : 4.4/5 (615 download)
Download or read book Radioiodination: Theory, Practice, and Biomedical Applications written by Mrinal K. Dewanjee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Author :
Publisher :
ISBN 13 :
Total Pages : 926 pages
Book Rating : 4.E/5 ( download)
Download or read book Isotopes and Radiation Technology written by and published by . This book was released on 1965 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. Allison
Publisher : Springer Science & Business Media
ISBN 13 : 1468426761
Total Pages : 321 pages
Book Rating : 4.4/5 (684 download)
Download or read book Structure and Function of Plasma Proteins written by A. Allison and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma proteins are of interest from many points of view. Biochemists have separated and purified numerous plasma proteins and studied their physical properties, aminoacid composition and sequence, the carbohydrate components of some, and binding of metals, hormones and other materials. Much work has also been carried out on the synthesis, rates of turnover and degradation of plasma proteins. Many plasma proteins show inherited variations, some of which (e.g. those of heptoglobins and transferrins) are common in various human populations while others (e.g. absence of lipoproteins or im munoglobins) are rare but important because of their association with clinical syndromes. Since blood is the most accessible bodily con stituent, geneticists have made good use of serum protein differences as genetic markers in family and population studies. Physiologists have long been interested in plasma proteins in relation to colloid osmotic pressure, transport of lipids, iron, hormones and other materials, the activities of renal glomeruli and tubules, the function of the liver, and many other bodily activities. Plasma proteins are also widely studied in relation to malnutrition and undernutrition, particularly that associated with defective intake of protein.
Author : F. E. McKinney
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.3/5 (91 download)
Download or read book Special Sources of Information on Isotopes written by F. E. McKinney and published by . This book was released on 1968 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
