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Radiation Damage In Biomolecular Systems
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Author :Gustavo García Gómez-Tejedor Publisher :Springer Science & Business Media ISBN 13 :9400725639 Total Pages :508 pages Book Rating :4.4/5 (7 download)
Book Synopsis Radiation Damage in Biomolecular Systems by : Gustavo García Gómez-Tejedor
Download or read book Radiation Damage in Biomolecular Systems written by Gustavo García Gómez-Tejedor and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.
Book Synopsis Radiation Damage in Biomolecular Systems by : Gustavo García Gómez-Tejedor
Download or read book Radiation Damage in Biomolecular Systems written by Gustavo García Gómez-Tejedor and published by Springer. This book was released on 2012-01-26 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.
Book Synopsis Radiation Damage in Biomolecular Systems by : Károly Tokési
Download or read book Radiation Damage in Biomolecular Systems written by Károly Tokési and published by AIP Conference Proceedings (Nu. This book was released on 2008-12-11 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the meeting was to review our progress in obtaining a detailed understanding of the fundamental interaction processes initiated by the deposition of various types of radiation within biological material. The program represents a strong interdisciplinary approach, covering the range from photon-, electron- and ion-molecule interactions, to the clinical applications.
Book Synopsis Radiation Damage in Biomolecular Systems by :
Download or read book Radiation Damage in Biomolecular Systems written by and published by . This book was released on 2008 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Damage in Biomolecular Systems 2007 by : Institute of Physics Publishing (Iop)
Download or read book Radiation Damage in Biomolecular Systems 2007 written by Institute of Physics Publishing (Iop) and published by . This book was released on 2009-06-16 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Damage in Biomolecular Systems by : Nigel Mason
Download or read book Radiation Damage in Biomolecular Systems written by Nigel Mason and published by . This book was released on 2004 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Damage in Biomolecular Systems by : Kevin McGuigan
Download or read book Radiation Damage in Biomolecular Systems written by Kevin McGuigan and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Damage of Biomolecular Systems: Nanoscale Insights Into Ion Beam Cancer Therapy by :
Download or read book Radiation Damage of Biomolecular Systems: Nanoscale Insights Into Ion Beam Cancer Therapy written by and published by . This book was released on 2013 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Gustavo García Gómez-Tejedor Publisher :Springer Science & Business Media ISBN 13 :9400725647 Total Pages :508 pages Book Rating :4.4/5 (7 download)
Book Synopsis Radiation Damage in Biomolecular Systems by : Gustavo García Gómez-Tejedor
Download or read book Radiation Damage in Biomolecular Systems written by Gustavo García Gómez-Tejedor and published by Springer Science & Business Media. This book was released on 2012-01-04 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.
Book Synopsis Effects of Radiation on Biological Systems by : Arnold Hicks Sparrow
Download or read book Effects of Radiation on Biological Systems written by Arnold Hicks Sparrow and published by . This book was released on 1955 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biological Radiation Effects by : Jürgen Kiefer
Download or read book Biological Radiation Effects written by Jürgen Kiefer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological action of radiation undoubtedly constitutes an issue of actual con cern, particularly after incidences like those in Harrisburg or Chernobyl. These considerations, however, were not the reason for writing this book although it is hoped that it will also be helpful in this respect. The interaction of radiation with biological systems is such an interesting research objective that to my mind no special justification is needed to pursue these problems. The combination of physics, chemistry and biology presents on one hand a fascinating challenge to the student, on the other, it may lead to insights which are not possible if the dif ferent subjects remain clearly separated. Special problems of radiation biology have quite often led to new approaches in physics (or vice versa), a recent example is "microdosimetry" (chapter 4). Biological radiation a9tion comprises all levels of biological organization. It starts with the absorption in essential atoms and molecules and ends with the development of cancer and genetic hazards to future generations. The structure of the book reflects this. Beginning with physical and chemical fundamentals, it then turns to a description of chemical and subcellular systems. Cellular effects form a large part since they are the basis for understanding all further responses. Reactions of the whole organism, concentrating on mammals and especially humans, are subsequently treated. The book concludes with a short discussion of problems in radiation protection and the application of radiation in medical therapy. These last points are necessarily short and somewhat superficial.
Book Synopsis Radiation Damage in Biomolecules and Cells by : Francesca Ballarini
Download or read book Radiation Damage in Biomolecules and Cells written by Francesca Ballarini and published by Mdpi AG. This book was released on 2023-04-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this Special Issue deal with the effects of ionizing radiation at molecular and cellular levels, as well as possible applications in medicine and radiation protection. In particular, some works analysed the early stages of the interaction between ionizing radiation and DNA focusing on DNA cluster damage, which is widely considered as an important step towards subsequent endpoints. Other studies investigated the consequences of hypoxia on the evolution of the initial DNA damage, and one work analysed genome-wide DNA alterations in irradiated human cells. Concerning radiation therapy, the response of cancer cells to different radiation types was characterized both in vitro and in vivo, and possible strategies to enhance such response were investigated; furthermore, FLASH radiotherapy was reviewed. In the framework of cancer therapy side effects, the consequences of high doses on gene expression in healthy cells were analyzed, and the RBE (Relative Biological Effectiveness) for late effects in the central nervous system was predicted by the BIANCA biophysical model. Finally, the protective role of melatonin and Vitamin D, as well as hypothermia, was reviewed, valine radiolysis was investigated, the changes in radio-sensitivity of embrios during the early developmental stages of the preimplantation were analyzed, and epigenetic modifications induced by ionizing radiation were reviewed.
Book Synopsis Physical and Chemical Mechanisms in Molecular Radiation Biology by : William A. Glass
Download or read book Physical and Chemical Mechanisms in Molecular Radiation Biology written by William A. Glass and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.
Book Synopsis Recovery from Radiation Damage in Biological Systems by : Atomic Energy of Canada Limited
Download or read book Recovery from Radiation Damage in Biological Systems written by Atomic Energy of Canada Limited and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biological Responses, Monitoring and Protection from Radiation Exposure by : K. P. Mishra
Download or read book Biological Responses, Monitoring and Protection from Radiation Exposure written by K. P. Mishra and published by . This book was released on 2015 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with urgent and timely issues related to radiation health effects and protection that are examined by both young researchers as well as experts. The book is organized into three major sections: biological responses, population monitoring and approaches to protection from radiation exposure. Contributors have provided state of the art research in their respective chapters. Radiation action produces damage to multiple targets in the exposed cells or human body and understanding of molecular mechanisms of the underlying processes becomes central to the monitoring of effects and health consequences of radiation exposure. Many experts have highlighted the outcome of epidemiological studies on human populations in high background radiation areas in different locations around the world as well as consequences and scopes for mitigating radiation health effects after radiation accidents such as Chernobyl in Ukraine and the Fukushima Daiichi Accident in Japan. This book also provides important direction for treatment of radiation for exposed victims. In the concluding chapters, contributors have provided new approaches for protection against ionizing radiation exposure. This book contains rich content on basic aspects of radiation induced cellular response which may give deeper insight to beginners in research, teaching, industry and regulatory authorities for basic understanding of radiobiological processes and molecular mechanisms. The book will prove an authentic reference source for updates in radiation science. It is hoped that students, teachers, experts, safety officers, regulatory officials and policy-makers will find the book handy for gaining a broad view of radiation damage to biological systems, monitoring health consequences and for new approaches in developing effective protection against radiation exposure.
Book Synopsis Advances in Radiation Biology by : Leroy G. Augenstein
Download or read book Advances in Radiation Biology written by Leroy G. Augenstein and published by Academic Press. This book was released on 2013-10-22 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 3, reflects a continuing effort to cover a wide spectrum of radiation science in this serial publication. The book contains six chapters and opens with a review of developments of physical theory in an area of interest to biophysicists. This is followed by subsequent chapters on problem of photodynamic action, which demonstrates the role of energy transfer in radiation damage development; the sensitization of biological systems by small molecules; and problems concerned with the identification and study of the biological effects of radioactive decay. Subsequent chapters deal with a survey of human radiation cytogenetics and progress in human radiobiology.
Download or read book 1st Nano-IBCT Conference 2011 written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
