Quantitative Fundamentals of Molecular and Cellular Bioengineering

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Publisher : MIT Press
ISBN 13 : 0262353970
Total Pages : 593 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Quantitative Fundamentals of Molecular and Cellular Bioengineering by : K. Dane Wittrup

Download or read book Quantitative Fundamentals of Molecular and Cellular Bioengineering written by K. Dane Wittrup and published by MIT Press. This book was released on 2020-01-07 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.

Quantitative Fundamentals of Molecular and Cellular Bioengineering

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Author :
Publisher : MIT Press
ISBN 13 : 0262042657
Total Pages : 593 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Quantitative Fundamentals of Molecular and Cellular Bioengineering by : K. Dane Wittrup

Download or read book Quantitative Fundamentals of Molecular and Cellular Bioengineering written by K. Dane Wittrup and published by MIT Press. This book was released on 2020-01-07 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.

Chemical Biophysics

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Publisher : Cambridge University Press
ISBN 13 : 1139470078
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Chemical Biophysics by : Daniel A. Beard

Download or read book Chemical Biophysics written by Daniel A. Beard and published by Cambridge University Press. This book was released on 2008-05-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.

Foundations of Cellular Neurophysiology

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Publisher : MIT Press
ISBN 13 : 0262293498
Total Pages : 709 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis Foundations of Cellular Neurophysiology by : Daniel Johnston

Download or read book Foundations of Cellular Neurophysiology written by Daniel Johnston and published by MIT Press. This book was released on 1994-11-02 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: with simulations and illustrations by Richard Gray Problem solving is an indispensable part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience provides comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It is the only neurophysiology text that gives detailed derivations of equations, worked examples, and homework problem sets (with complete answers). Developed from notes for the course that the authors have taught since 1983, Foundations of Cellular Neurophysiology covers cellular neurophysiology (also some material at the molecular and systems levels) from its physical and mathematical foundations in a way that is far more rigorous than other commonly used texts in this area.

Applied Cell and Molecular Biology for Engineers

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Publisher : Lulu.com
ISBN 13 : 0359582125
Total Pages : 348 pages
Book Rating : 4.3/5 (595 download)

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Book Synopsis Applied Cell and Molecular Biology for Engineers by : Gabi Nindl Waite

Download or read book Applied Cell and Molecular Biology for Engineers written by Gabi Nindl Waite and published by Lulu.com. This book was released on with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioengineering Fundamentals

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Publisher :
ISBN 13 : 9780134637433
Total Pages : 0 pages
Book Rating : 4.6/5 (374 download)

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Book Synopsis Bioengineering Fundamentals by : Ann Saterbak

Download or read book Bioengineering Fundamentals written by Ann Saterbak and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For sophomore-level courses in Bioengineering, Biomedical Engineering, and related fields. A unifying, interdisciplinary approach to the fundamentals of bioengineering Now in its 2nd Edition, Bioengineering Fundamentals combines engineering principles with technical rigor and a problem-solving focus, ultimately taking a unifying, interdisciplinary approach to the conservation laws that form the foundation of bioengineering: mass, energy, charge, and momentum. The text emphasizes fundamental concepts, practical skill development, and problem-solving strategies while incorporating a wide array of examples and case studies. This 2nd Edition has been updated and expanded with new and clarified content, plus new homework and example problems.

Biomechanics of Movement

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Publisher : MIT Press
ISBN 13 : 0262359197
Total Pages : 396 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Biomechanics of Movement by : Thomas K. Uchida

Download or read book Biomechanics of Movement written by Thomas K. Uchida and published by MIT Press. This book was released on 2021-01-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: An engaging introduction to human and animal movement seen through the lens of mechanics. How do Olympic sprinters run so fast? Why do astronauts adopt a bounding gait on the moon? How do running shoes improve performance while preventing injuries? This engaging and generously illustrated book answers these questions by examining human and animal movement through the lens of mechanics. The authors present simple conceptual models to study walking and running and apply mechanical principles to a range of interesting examples. They explore the biology of how movement is produced, examining the structure of a muscle down to its microscopic force-generating motors. Drawing on their deep expertise, the authors describe how to create simulations that provide insight into muscle coordination during walking and running, suggest treatments to improve function following injury, and help design devices that enhance human performance.

Mathematical Modeling in Systems Biology

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Publisher : MIT Press
ISBN 13 : 0262545829
Total Pages : 423 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls

Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Biomedical Engineering

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Publisher : Cambridge University Press
ISBN 13 : 131629868X
Total Pages : 785 pages
Book Rating : 4.3/5 (162 download)

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Book Synopsis Biomedical Engineering by : W. Mark Saltzman

Download or read book Biomedical Engineering written by W. Mark Saltzman and published by Cambridge University Press. This book was released on 2015-05-21 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this popular introductory undergraduate textbook uses examples, applications, and profiles of biomedical engineers to show students the relevance of the theory and how it can be used to solve real problems in human medicine. The essential molecular biology, cellular biology, and human physiology background is included for students to understand the context in which biomedical engineers work. Updates throughout highlight important advances made over recent years, including iPS cells, microRNA, nanomedicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Over two hundred quantitative and qualitative exercises, many new to this edition, help consolidate learning, whilst a solutions manual, password-protected for instructors, is available online. Finally, students can enjoy an expanded set of leader profiles in biomedical engineering within the book, showcasing the broad range of career paths open to students who make biomedical engineering their calling.

Quantitative Imaging in Cell Biology

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Publisher : Academic Press
ISBN 13 : 0124202012
Total Pages : 609 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis Quantitative Imaging in Cell Biology by :

Download or read book Quantitative Imaging in Cell Biology written by and published by Academic Press. This book was released on 2014-06-25 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Principles of Biomedical Engineering, Second Edition

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Publisher : Artech House
ISBN 13 : 1630817120
Total Pages : 509 pages
Book Rating : 4.6/5 (38 download)

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Book Synopsis Principles of Biomedical Engineering, Second Edition by : Sundararajan Madihally

Download or read book Principles of Biomedical Engineering, Second Edition written by Sundararajan Madihally and published by Artech House. This book was released on 2019-12-31 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition of an Artech House classic introduces readers to the importance of engineering in medicine. Bioelectrical phenomena, principles of mass and momentum transport to the analysis of physiological systems, the importance of mechanical analysis in biological tissues/ organs and biomaterial selection are discussed in detail. Readers learn about the concepts of using living cells in various therapeutics and diagnostics, compartmental modeling, and biomedical instrumentation. The book explores fluid mechanics, strength of materials, statics and dynamics, basic thermodynamics, electrical circuits, and material science. A significant number of numerical problems have been generated using data from recent literature and are given as examples as well as exercise problems. These problems provide an opportunity for comprehensive understanding of the basic concepts, cutting edge technologies and emerging challenges. Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Moreover, you find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics. Structured as a complete text for students with some engineering background, the book also makes a valuable reference for professionals new to the bioengineering field. This authoritative textbook features numerous exercises and problems in each chapter to help ensure a solid understanding of the material.

Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 0203011422
Total Pages : 388 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Tissue Engineering by : Bernhard Palsson

Download or read book Tissue Engineering written by Bernhard Palsson and published by CRC Press. This book was released on 2003-03-26 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the new Principles and Applications in Engineering series, Tissue Engineering provides an overview of the major physiologic systems of current interest to biomedical engineers: cardiovascular, endocrine, nervous, visual, auditory, gastrointestinal, and respiratory. It contains useful definitions, tables of basic physiologic data, and an

Strong Water

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Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Strong Water by : Thomas H. Chilton

Download or read book Strong Water written by Thomas H. Chilton and published by . This book was released on 1968 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioprocess Engineering Principles

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Publisher : Elsevier
ISBN 13 : 0080528120
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Bioprocess Engineering Principles by : Pauline M. Doran

Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Elsevier. This book was released on 1995-04-03 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.

Thermodynamics for Chemical Engineers

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Publisher : MIT Press (MA)
ISBN 13 : 9780262523981
Total Pages : 518 pages
Book Rating : 4.5/5 (239 download)

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Book Synopsis Thermodynamics for Chemical Engineers by : K. E. Bett

Download or read book Thermodynamics for Chemical Engineers written by K. E. Bett and published by MIT Press (MA). This book was released on 2003-02-01 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the thermodynamics needed by chemical engineers both in their engineering and in their chemistry; it is intended for use in all undergraduate and some graduate-level courses. The authors emphasize a rigorous yet concise presentation of the fundamental chemical concepts governing the behavior of single and multicomponent mixtures, including phase and chemical equilibria. In the application of these concepts, consideration is given to the presentation of experimentally measured thermodynamic properties, and to their prediction for real fluids and their mixtures using methods founded on statistical mechanics. Several applications involving the transfer of heat and work that are of special importance to chemical engineers are studied in detail to show the use of thermodynamics in improving performance. The book is written in SI units and contains worked examples, exercises, and problems.

Cellular Biophysics

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Publisher : MIT Press
ISBN 13 : 9780262231831
Total Pages : 738 pages
Book Rating : 4.2/5 (318 download)

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Book Synopsis Cellular Biophysics by : Thomas Fischer Weiss

Download or read book Cellular Biophysics written by Thomas Fischer Weiss and published by MIT Press. This book was released on 1996 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book written to preserve the wisdom of the ancient healing sages of China, and to provide the conceptual tools needed for its practical application in healing diseases of the modern world.

Numerical Methods in Biomedical Engineering

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Publisher : Elsevier
ISBN 13 : 0080470807
Total Pages : 628 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Numerical Methods in Biomedical Engineering by : Stanley Dunn

Download or read book Numerical Methods in Biomedical Engineering written by Stanley Dunn and published by Elsevier. This book was released on 2005-11-21 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerical Modeling in Biomedical Engineering brings together the integrative set of computational problem solving tools important to biomedical engineers. Through the use of comprehensive homework exercises, relevant examples and extensive case studies, this book integrates principles and techniques of numerical analysis. Covering biomechanical phenomena and physiologic, cell and molecular systems, this is an essential tool for students and all those studying biomedical transport, biomedical thermodynamics & kinetics and biomechanics. - Supported by Whitaker Foundation Teaching Materials Program; ABET-oriented pedagogical layout - Extensive hands-on homework exercises