Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies

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Publisher : Frontiers Media SA
ISBN 13 : 2889450244
Total Pages : 131 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies by : Hervé Emonard

Download or read book Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies written by Hervé Emonard and published by Frontiers Media SA. This book was released on 2016-11-22 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically acting on ECM homeostasis. Matricellular receptors mediate numerous signalings from the extracellular environment to cell nucleus and drive main biological functions that are cell growth, survival and migration. Numerous data from the last decade evidence that matricellular receptors are biosensors that allow to a tumor cell answering to microenvironmental variations, and in this sense they are important contributors to tumor cell malignancy. Matricellular receptors represent thus valuable targets for the development of original anti-cancer strategies. Original reports, bibliographic reviews or hypotheses are welcome to improve the basic knowledge of matricellular receptor properties, their spatio-temporal regulation, the dynamic formation of complex receptors and the impact of such interactions on the invasive properties of tumor cells. Biological, biophysical and pharmacological, as well as in silico contributions will be appreciated.

Acupuncture in Practice

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Publisher :
ISBN 13 : 9780443050497
Total Pages : 482 pages
Book Rating : 4.0/5 (54 download)

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Book Synopsis Acupuncture in Practice by : Hugh MacPherson (Ph. D.)

Download or read book Acupuncture in Practice written by Hugh MacPherson (Ph. D.) and published by . This book was released on 1997 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by THE leading lights in the field of integrating acupuncture into a Western medical system, this book bridges the gap between the theoretical foundations of acupuncture and its application in a modern Western clinical context. Each case history focuses on the complexities and dilemmas of treatment that are tackled, providing valuable insights by experienced practitioners into the management of a course of acupuncture treatment.

Caterpillar Club Survivor

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Publisher :
ISBN 13 : 9780646477770
Total Pages : 124 pages
Book Rating : 4.4/5 (777 download)

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Book Synopsis Caterpillar Club Survivor by : Ross Smith Stagg

Download or read book Caterpillar Club Survivor written by Ross Smith Stagg and published by . This book was released on 2007 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spitfire pilot Ross Smith Stagg was one of 33 Allied airmen to defend Darwin against Japanese invasion on May 2, 1943. As one of 14 pilots shot down or experience mechanical failure in the ensuing battle, he parachuted into the sea 18 km from land, 100 km southwest of Darwin in the Fogg Bay area. He reached the shore in a dinghy. For the next 15 days he trudged through inhospitable country in a futile attempt to return to Strauss airbase. What should have been a few days walk turned into his worst possible nightmare as he stumbled aimlessly through mosquito and crocodile infested swamps. "It was almost six days I'd been without sleep, apart from a short period of unconsciousness and those few moments before I fell out of that tree," he said. " I became demented by the cavalcade of mosquitoes and hallucinating badly". His experience was only to worsen - he waded halfway across a tidal river to be confronted by a large saltie. Darwin historian John Haslett help Stagg map the original route by retracing his steps, even managing to relocate an American Kittyhawk Stagg found crashed in the middle of nowhere.

Biomarkers of the Tumor Microenvironment

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Publisher :
ISBN 13 : 9783030989514
Total Pages : 0 pages
Book Rating : 4.9/5 (895 download)

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Book Synopsis Biomarkers of the Tumor Microenvironment by : Lars A. Akslen

Download or read book Biomarkers of the Tumor Microenvironment written by Lars A. Akslen and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.

Biomarkers of the Tumor Microenvironment

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Publisher : Springer
ISBN 13 : 331939147X
Total Pages : 537 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Biomarkers of the Tumor Microenvironment by : Lars A. Akslen

Download or read book Biomarkers of the Tumor Microenvironment written by Lars A. Akslen and published by Springer. This book was released on 2017-08-02 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.