Progress In Migraine Research

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Migraine: A Neuroinflammatory Disease?

Author : Egilius L.H. Spierings
Publisher : Springer Science & Business Media
ISBN 13 : 9783764362317
Total Pages : 190 pages
Book Rating : 4.3/5 (623 download)

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Book Synopsis Migraine: A Neuroinflammatory Disease? by : Egilius L.H. Spierings

Download or read book Migraine: A Neuroinflammatory Disease? written by Egilius L.H. Spierings and published by Springer Science & Business Media. This book was released on 2002-01-01 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains reviews by a renowned group of clinicians and scientists, which consider in great depth the potential involvement of neurogenic inflammation in the pathogenesis of migraine and inhibition of this putative mechanism as a possible mode of action of antimigraine medications. The authors carefully consider current and future potential therapeutic approaches for the abortive as well as preventive treatment of migraine. The pioneering work by Professor Michael A. Moskowitz's group at Harvard gave rise to the "neurogenic hypothesis" of migraine pathogenesis and to an intel lectual framework for many aspects of migraine research through a detailed phar macological characterization of the trigeminovascular system. This knowledge then spurred detailed research worldwide into the roles of the dural vasculature, trigem inal nerve fibers, and sensory neuropeptides, such as substance P and calcitonin gene-related peptide, in migraine. Similar in-depth investigations have not been made of the role of the seventh cranial parasympathetic nerves but this area war rants further study because of its potential for interactions with the trigeminovas cular system and its clear involvement in cluster headache."

Migraine

Author : Katherine Foxhall
Publisher : Johns Hopkins University Press
ISBN 13 : 1421429489
Total Pages : 293 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Migraine by : Katherine Foxhall

Download or read book Migraine written by Katherine Foxhall and published by Johns Hopkins University Press. This book was released on 2019-06-18 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cultural, social, and medical history of migraine. For centuries, people have talked of a powerful bodily disorder called migraine, which currently affects about a billion people around the world. Yet until now, the rich history of this condition has barely been told. In Migraine, award-winning historian Katherine Foxhall reveals the ideas and methods that ordinary people and medical professionals have used to describe, explain, and treat migraine since the Middle Ages. Touching on classical theories of humoral disturbance and medieval bloodletting, Foxhall also describes early modern herbal remedies, the emergence of neurology, and evolving practices of therapeutic experimentation. Throughout the book, Foxhall persuasively argues that our current knowledge of migraine's neurobiology is founded on a centuries-long social, cultural, and medical history. This history, she demonstrates, continues to profoundly shape our knowledge of this complicated disease, our attitudes toward people who have migraine, and the sometimes drastic measures that we take to address pain. Migraine is an intimate look at how cultural attitudes and therapeutic practices have changed radically in response to medical and pharmaceutical developments. Foxhall draws on a wealth of previously unexamined sources, including medieval manuscripts, early-modern recipe books, professional medical journals, hospital case notes, newspaper advertisements, private diaries, consultation letters, artworks, poetry, and YouTube videos. Deeply researched and beautifully written, this fascinating and accessible study of one of our most common, disabling—and yet often dismissed—disorders will appeal to physicians, historians, scholars in medical humanities, and people living with migraine alike.

Progress in Migraine Research

Author : Amadeo O. Fernandez
Publisher : Nova Science Publishers
ISBN 13 :
Total Pages : 230 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Progress in Migraine Research by : Amadeo O. Fernandez

Download or read book Progress in Migraine Research written by Amadeo O. Fernandez and published by Nova Science Publishers. This book was released on 2007 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine is a painful neurological condition, of which the most common symptom is an intense and disabling episodic headache. Migraine headaches are usually characterised by severe pain on one or both sides of the head. Absent serious head injuries, stroke, and tumours, the recurring severity of the pain indicates a vascular headache rather than a tension headache. Migraines are often accompanied by photophobia (hypersensitivity to light), phonophobia (hypersensitivity to sound) and nausea. Migraine is three times more common in women than in men. Some individuals can predict the onset of a migraine because it is preceded by an 'aura', visual disturbances that appear as flashing lights, zig-zag lines or a temporary loss of vision. People with migraine tend to have recurring attacks triggered by a lack of food or sleep, exposure to light, or hormonal irregularities (only in women). Anxiety, stress, or relaxation after stress can also be triggers. For many years, scientists believed that migraines were linked to

ABC of Headache

Author : Anne MacGregor
Publisher : John Wiley & Sons
ISBN 13 : 1118682009
Total Pages : 88 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis ABC of Headache by : Anne MacGregor

Download or read book ABC of Headache written by Anne MacGregor and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its different presentations, headache is one of the most commonsymptoms seen by family practitioners. The difficulty is indiagnosing the cause of the headache so that the appropriatetreatment is provided, or if referral to a specialist is therecommended course of action. The ABC of Headache helps with this dilemma and guidesthe healthcare professional to look for the possible causes ofpresenting symptoms. Based on real case histories, each chapterguides the reader from symptoms through to diagnosis andmanagement. This new ABC is a highly illustrated, informative, andpractical source of knowledge. With links to further informationand resources, it is a valuable text for healthcare professionalsat all levels of practice and training.

Headache and Migraine Biology and Management

Author : Seymour Diamond
Publisher : Academic Press
ISBN 13 : 0128011629
Total Pages : 334 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Headache and Migraine Biology and Management by : Seymour Diamond

Download or read book Headache and Migraine Biology and Management written by Seymour Diamond and published by Academic Press. This book was released on 2015-03-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field. - A practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs - Features chapters from leading physicians and researchers in headache medicine - Full-color text that includes both an overview of multiple disciplines and discusses the measures that can be used to treat headaches

Pituitary Adenylate Cyclase-Activating Polypeptide

Author : Hubert Vaudry
Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Neurophysiology of the Migraine Brain

Author : Gianluca Coppola
Publisher : Springer Nature
ISBN 13 : 3030565386
Total Pages : 236 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Neurophysiology of the Migraine Brain by : Gianluca Coppola

Download or read book Neurophysiology of the Migraine Brain written by Gianluca Coppola and published by Springer Nature. This book was released on 2020-10-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Roughly one in every five patients referred to a neurologist suffers from headaches; the majority have migraines. Although headache specialists understand migraine on a clinical basis, the pathophysiological changes that provoke and accompany the development of a migraine attack continue to elude us. Several decades have passed since the pioneering electroencephalographic study by Golla and Winter (1959), which underscored the role of abnormal rhythmic activities in migraine. Since then, there have been substantial advances in the field; a wealth of neurophysiological studies has enriched our understanding of the pathophysiological facets of the migraine pathology. Virtually every known technique of clinical electrophysiology has since been used to study the migraine brain and, more recently, new neurophysiological tools have been added to the arsenal. Nevertheless, applying the principles of peripheral and central neuromodulation offers a promising way to transfer the principles of synaptic plasticity to the patient’s bedside. This book belongs to the Headache Series endorsed by the European Headache Federation. Written by internationally recognized experts in their respective fields, it covers all aspects of clinical neurophysiological methods that represent significant advances in our understanding of the pathophysiology of migraine. It will offer a valuable toolkit for beginners, and a reference guide for experts.

The Migraine Brain

Author : David Borsook
Publisher : Oxford University Press, USA
ISBN 13 : 019975456X
Total Pages : 400 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis The Migraine Brain by : David Borsook

Download or read book The Migraine Brain written by David Borsook and published by Oxford University Press, USA. This book was released on 2012-07-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.

Not Tonight

Author : Joanna Kempner
Publisher : University of Chicago Press
ISBN 13 : 022617915X
Total Pages : 260 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Not Tonight by : Joanna Kempner

Download or read book Not Tonight written by Joanna Kempner and published by University of Chicago Press. This book was released on 2014-10-08 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine is an extraordinarily common, disabling, and painful disorder that affects over 36 million Americans and costs the US economy at least $32 billion per year. Nevertheless, it is frequently dismissed, ignored, and delegitimised. In this book, Joanna Kempner argues that this general dismissal of migraine can be traced back to the gendered social values embedded in the way we talk about, understand, and make policies for people in pain.

Pathophysiology of Headaches

Author : Messoud Ashina
Publisher : Springer
ISBN 13 : 3319156217
Total Pages : 277 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Pathophysiology of Headaches by : Messoud Ashina

Download or read book Pathophysiology of Headaches written by Messoud Ashina and published by Springer. This book was released on 2015-04-14 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

White Matter Diseases

Author : Massimo Filippi
Publisher : Springer Nature
ISBN 13 : 303038621X
Total Pages : 215 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis White Matter Diseases by : Massimo Filippi

Download or read book White Matter Diseases written by Massimo Filippi and published by Springer Nature. This book was released on 2020-02-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.

Neurobiology of Brain Disorders

Author : Michael J. Zigmond
Publisher : Elsevier
ISBN 13 : 0123982804
Total Pages : 823 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Neurobiology of Brain Disorders by : Michael J. Zigmond

Download or read book Neurobiology of Brain Disorders written by Michael J. Zigmond and published by Elsevier. This book was released on 2014-12-03 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. - Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment - Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain - Illustrated in full color - Each chapter provides in-text summary points, special feature boxes, and research questions - Provides an up-to-date synthesis of primary source material

Drug-Induced Headache

Author : Hans-Christoph Diener
Publisher : Springer Science & Business Media
ISBN 13 : 3642733271
Total Pages : 174 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Drug-Induced Headache by : Hans-Christoph Diener

Download or read book Drug-Induced Headache written by Hans-Christoph Diener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Atlas of Clinical Neurology

Author : Roger N. Rosenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1475745524
Total Pages : 566 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Atlas of Clinical Neurology by : Roger N. Rosenberg

Download or read book Atlas of Clinical Neurology written by Roger N. Rosenberg and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: '---~~~~-~~---------------. . . . . . . . . -. . . . . . . . . . . . . . . . . . . -. . . . . . . . . . . . . . . . . . . . . . . . . 41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ••••••• he year 2001 marks the beginning of a new millenium, and (chromosome 1) result in dominantly inherited AD. A major risk T the second edition of the Atlas of Clinical Neurology high factor for AD is the presence of the E4 allele of apolipoprotein E lights and underscores the enormous strides being made in (chromosome 19). Additional detailed images related to the the biologic understanding of neurologic disease. Neurology is a dementias are included in the second edition of the Atlas. These highly visual specialty. The neurologic examination, magnetic reso clinical-molecular correlations are all very recent and attest to the nance imaging, electroencephalography, positron-emission tomo scientific vigor of current neuroscientific research. It is my view that graphic (PET) and functional magnetic resonance (fMRI) scan these new data will lead in the near future to effective new therapy ning, and light- and electron-microscopy are examples of visual for AD that will slow its rate of progress and reduce significantly images that define neurologic disease and normal brain functions. the incidence of this major, debilitating disease. Positron-emission This Atlas of Clinical Neurology has been designed to provide a pic tomographic and fMRI brain scanning have effectively defined torial comprehensive visual exposition and integration of all aspects regional brain areas for behaviors.

The Migraine Brain

Author : Carolyn Bernstein
Publisher : Simon and Schuster
ISBN 13 : 141654769X
Total Pages : 371 pages
Book Rating : 4.4/5 (165 download)

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Book Synopsis The Migraine Brain by : Carolyn Bernstein

Download or read book The Migraine Brain written by Carolyn Bernstein and published by Simon and Schuster. This book was released on 2009-07-14 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Draws on the latest scientific findings to identify the unique characteristics, chemical makeups, and structural differences of migraine-prone brains, offering insight into the role of the central nervous system while outlining a comprehensive program to reduce the frequency and intensity of headaches. Reprint.

Sports-Related Concussions in Youth

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309288037
Total Pages : 215 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Sports-Related Concussions in Youth by : National Research Council

Download or read book Sports-Related Concussions in Youth written by National Research Council and published by National Academies Press. This book was released on 2014-02-04 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.

Neurobiological Basis of Migraine

Author : Turgay Dalkara
Publisher : John Wiley & Sons
ISBN 13 : 1118967194
Total Pages : 421 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Neurobiological Basis of Migraine by : Turgay Dalkara

Download or read book Neurobiological Basis of Migraine written by Turgay Dalkara and published by John Wiley & Sons. This book was released on 2017-08-07 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published with the New York Academy of Sciences A timely, broad-ranging exploration of the neurobiological basis and molecular mechanisms of migraines Migraines impact the lives of a significant portion of the world's population, afflicting sufferers with severe pain, nausea, and often visual impairment. The WHO views migraines as an important public health issue, and ranks them in its top twenty most disabling illnesses. Neurobiological Basis of Migraine reviews the latest advances made in our understanding of the primary basic mechanisms of migraine headache and provides valuable insights into how these findings are being translated into novel treatment and prevention strategies around the world. Written for researchers and clinicians alike, the book features edited contributions from distinguished experts in the field, taking a focused, yet wide-ranging approach to the subject. It begins by exploring the pathways and networks mediating migraine headaches, their underlying physiological mechanisms, characteristics of visceral pain, and the concept of dural neurogenic inflammation. From there the authors delve into the mechanisms sustaining the head pain and photophobia associated with migraines, and they review the pharmacology of newly discovered migraine treatments. These basic chapters are followed by clinical and genetic studies linking to key issues, including cortical spreading depression, ion channels, transporters, and epilepsy. Reviews of the latest advances in our understanding of the neurobiological basis of migraine Translates important research findings from around the globe into novel treatments strategies currently being investigated Provides researchers and clinicians with a deep understanding of the primary mechanisms of migraine from migraine modeling to clinical applications Includes contributions by many of the most respected researchers in the field, world-wide Discusses exciting recent developments in migraine mutations and their role in CSD, as well as the role of CSD in aura and trigeminal activation Timely, comprehensive, and authoritative, Neurobiological Basis of Migraine is an indispensable working resource for clinicians and migraine, headache, and pain researchers, including neurobiologists, neuropharmacologists, neurologists, and vascular neurobiologists, as well as graduate students in those fields who are involved in researching migraine headaches.