Primary Mesenchymal Cells

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Primary Mesenchymal Cells

Author : F. Koller
Publisher : Springer Science & Business Media
ISBN 13 : 0306468700
Total Pages : 244 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Primary Mesenchymal Cells by : F. Koller

Download or read book Primary Mesenchymal Cells written by F. Koller and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human body contains many specialized tissues that are capable of fulfilling an incredible variety of functions necessary for our survival. This volume in the Human Cell Culture Series focuses on mesenchymal tissues and cells. The in vitro study of mesenchymal cells is perhaps the oldest form of human cell culture, beginning with the culturing of fibroblasts. Fibroblasts have long been generically described in the literature, arising from many tissue types upon in vitro cell culture. However, recent studies, many enabled by new molecular biology techniques, have shown considerable diversity in fibroblast type and function, as described within this volume. Mesenchymal tissue types that are described within include bone, cartilage, tendons and ligaments, muscle, adipose tissue, and skin (dermis). The proper function of these tissues is predominantly dependent upon the proper proliferation, differentiation, and function of the mesenchymal cells which make up the tissue. Recent advancements in primary human mesenchymal cell culture have led to remarkable progress in the study of these tissues. Landmark experiments have now demonstrated a stem cell basis for many of these tissues, and, furthermore, significant plasticity and inter-conversion of stem cells between these tissues, resulting in a great deal of contemporary excitement and controversy. Newly-developed mesenchymal cell culture techniques have even lead to novel clinical practices for the treatment of disease.

The Sea Urchin Embryo

Author : G. Czihak
Publisher : Springer Science & Business Media
ISBN 13 : 3642659640
Total Pages : 719 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Sea Urchin Embryo by : G. Czihak

Download or read book The Sea Urchin Embryo written by G. Czihak and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sea urchin eggs are objects of wonder for the student who sees them for the first time under the microscope. The formation of the fertil ization membrane after insemination, the beauty of mitotic cleavage, the elegant swimming of embryos, remain an esthetic pleasure even for the eyes of seasoned investigators. But sea urchin eggs have other, more practical, advantages: they lend themselves to surgical operation without difficulty and they heal perfectly; they can be obtained in very large amounts and represent thus an extremely favorable material for biochemists and molecular embryologists. It is not surprising that, in view of these exceptional advantages, sea urchin eggs have attracted the interest of innumerable biologists since O. HERTWIG discovered the fusion of the pronuclei (amphimixy), in Paracentrotus lividus, almost a century ago. The purpose of the present book is to present, in a complete and orderly fashion, the enormous amount of information which has been gathered, in the course of a hun dred years of sea urchin embryology. JOSEPH NEEDHAM, in 1930, was still able to present all that was known, at that time, on the biochemistry of all possible species of developing eggs and embryos in his famous "Chemical Embryology" (Cambridge University Press) . It would no longer be possible for one man to write a modern version of what was a "Bible" for the young embryologists of forty years ago.

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Mesenchymal Stem Cells in Human Health and Diseases

Author : Ahmed El-Hashash
Publisher : Academic Press
ISBN 13 : 0128205334
Total Pages : 230 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Mesenchymal Stem Cells in Human Health and Diseases by : Ahmed El-Hashash

Download or read book Mesenchymal Stem Cells in Human Health and Diseases written by Ahmed El-Hashash and published by Academic Press. This book was released on 2020-01-07 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Mesenchymal Stem Cell Assays and Applications

Author : Mohan C Vemuri
Publisher : Humana Press
ISBN 13 : 9781493957798
Total Pages : 534 pages
Book Rating : 4.9/5 (577 download)

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Book Synopsis Mesenchymal Stem Cell Assays and Applications by : Mohan C Vemuri

Download or read book Mesenchymal Stem Cell Assays and Applications written by Mohan C Vemuri and published by Humana Press. This book was released on 2017-05-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stem Cells have seen an unprecedented level of interest in the last decade, primarily due to their relative ease of isolation, the large numbers of cells present in the adult, and the ability to propagate these cells in culture. In Mesenchymal Stem Cell Assays and Applications, expert researchers from across the globe explore the latest techniques to propagate, characterize, and engineer this special cell type. Chapters outline a set of protocols and assays used by leading investigators in the field, providing standards that can be applied by all researchers to the population of cells used in their experiments. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Ground-breaking and current, Mesenchymal Stem Cell Assays and Applications is a necessary handbook for all researchers working with this ambiguous population of cells.

Human Mesenchymal Stem Cells

Author : Mitchell Khan
Publisher : Nova Science Publishers
ISBN 13 : 9781536192247
Total Pages : 134 pages
Book Rating : 4.1/5 (922 download)

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Book Synopsis Human Mesenchymal Stem Cells by : Mitchell Khan

Download or read book Human Mesenchymal Stem Cells written by Mitchell Khan and published by Nova Science Publishers. This book was released on 2021 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In Chapter 1, the COVID-19 pandemic and the damage mechanisms on the cellular level which can be ameliorated with the cellular therapies is thoroughly evaluated. Previous and ongoing stem cell clinical trial data from diseases with similar symptoms is gathered. All this accumulated data and current clinical trial results indicate that the cellular therapies could be the most effective treatment option for COVID-19 patients to ameliorate the damaged tissues and save lives. In Chapter 2, the authors examine activated mesenchymal stem cells for stroke repair. Stem Cell treatment has shown recovery in animal models of stroke, indicating an improved regenerative and repair potential. Though stem cells are still being used in clinical trials, there is no evidence that they enhance recovery in ischemic stroke patients. Nevertheless, the multipotent mesenchymal stem has widely been explored for stroke recovery. An'Activated MSC' as a therapeutic alternative to tackling ischemic stroke is proposed, thereby the activation of MSCs by cytokines, growth factors, hypoxia, pharmacological drugs, etc., could be a novel approach to improving stroke patients' responses to receiving MSCs. In Chapter 3, the potential benefits of in vitro culture of therapeutic stem cells in the presence of HB along with the ketogenic diet, whereby higher physiological concentrations of ketone bodies can be achieved in vivo, as an adjuvant to stem cell transplantation is assessed"--

Kidney Transplantation, Bioengineering, and Regeneration

Author : Giuseppe Orlando
Publisher : Academic Press
ISBN 13 : 0128018364
Total Pages : 1253 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Kidney Transplantation, Bioengineering, and Regeneration by : Giuseppe Orlando

Download or read book Kidney Transplantation, Bioengineering, and Regeneration written by Giuseppe Orlando and published by Academic Press. This book was released on 2017-06-08 with total page 1253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Bone and Cartilage Regeneration

Author : Phuc Van Pham
Publisher : Springer
ISBN 13 : 3319401440
Total Pages : 316 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Bone and Cartilage Regeneration by : Phuc Van Pham

Download or read book Bone and Cartilage Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2017-01-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Mesenchymal Stem Cell Derived Exosomes

Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 287 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Comparative Oncology

Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)

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Book Synopsis Comparative Oncology by : Alecsandru Ioan Baba

Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organogenesis in Development

Author : Peter Koopman
Publisher : Academic Press
ISBN 13 : 0123809134
Total Pages : 455 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Organogenesis in Development by : Peter Koopman

Download or read book Organogenesis in Development written by Peter Koopman and published by Academic Press. This book was released on 2010-08-04 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. Summarizes the key morphological and cellular events Emphasizes up-to-date research relating to molecular control mechanisms Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease Distils common themes and differences for comparative studies Highlights key remaining questions and sets the agenda for future research

Lymphoid Organogenesis

Author : Fritz Melchers
Publisher : Springer Science & Business Media
ISBN 13 : 9783540675693
Total Pages : 240 pages
Book Rating : 4.6/5 (756 download)

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Book Synopsis Lymphoid Organogenesis by : Fritz Melchers

Download or read book Lymphoid Organogenesis written by Fritz Melchers and published by Springer Science & Business Media. This book was released on 2000-09-04 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been clear for a long time that after transplantation of a lymphoid organ, hematopoietic stem cells can regenerate the compartments of the organ, provided that the rest of its architecture - the strome, the epithelia and the vessels - is intact. Ahead lies the even greater challenge to assemble also these other architectural elements of a lymphoid organ by transplanting stem cells. The workshop on lymphoid organogenesis was convened to review current knowledge of and experimental skills involved in this grand project to build a lymphoid organ from its individual cellular components.

Stem Cells in Marine Organisms

Author : Baruch Rinkevich
Publisher : Springer Science & Business Media
ISBN 13 : 904812767X
Total Pages : 376 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Stem Cells in Marine Organisms by : Baruch Rinkevich

Download or read book Stem Cells in Marine Organisms written by Baruch Rinkevich and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do real stem cells and stem cell lineages exist in lower organisms? Can stem cells from one organism parasitize the soma and/or the germ line of conspecifics? Can differentiated cells in marine organisms be re-programmed to regenerate tissues, organs and appendages through novel de-differentiation, transdifferentiation, or re-differentiation processes, leading to virtually all three germ layers, including the germline? The positive answers to above questions open a new avenue in stem cell research: the biology of stem cells in marine organisms. It is therefore unfortunate that while the literature on stem cell from terrestrial organisms is rich and expanding at an exponential rate, investigations on marine organisms’ stem cells are very limited and scarce. By presenting theoretical chapters, overview essays and specific research results, this book summarises the knowledge and the hypotheses on stem cells in marine organisms through major phyla and specific model organisms. The study on stem cells from marine invertebrates may shed lights on mechanisms promoting immunity, developmental biology, regeneration and budding processes in marine invertebrates, body maintenance, aging and senescence. It aims in encouraging a larger scientific community to follow and study the novel phenomena of stem cells behaviours as depicted from the few currently studied marine invertebrates.

An Atlas of Comparative Vertebrate Histology

Author : Donald B. McMillan
Publisher : Academic Press
ISBN 13 : 0124095976
Total Pages : 636 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis An Atlas of Comparative Vertebrate Histology by : Donald B. McMillan

Download or read book An Atlas of Comparative Vertebrate Histology written by Donald B. McMillan and published by Academic Press. This book was released on 2018-06-04 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Comparative Vertebrate Histology looks at the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates. The authors focus their microscope on commonly seen vertebrates as well as ‘non-standard’ species, such as lamprey, hagfish, dogfish, skate, rock bass, cod, river catfish, toad, amphiuma, leopard and bull frog, garter and brown snake, Coturnix quail and cowbird. The study of comparative histology in the vertebrates helps students and researchers alike understand how various groups have addressed similar problems, opening doors to interesting research possibilities. Not all vertebrates follow the mammalian model of tissue and organ structure. When dealing with unique species, we see some structures taken beyond their ‘normal’ function. Comparative histology allows us to understand the structural responses underlying the physiology unique to each vertebrate group. Presents the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates Includes an image gallery with over 500 flat images and 50+ virtual microscopy slides Contains electronic content features cross linking between text, tables and the image gallery

Tissue Engineering and Regenerative Medicine

Author : Phuc Van Pham
Publisher : Springer
ISBN 13 : 303019857X
Total Pages : 225 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Tissue Engineering and Regenerative Medicine by : Phuc Van Pham

Download or read book Tissue Engineering and Regenerative Medicine written by Phuc Van Pham and published by Springer. This book was released on 2019-08-14 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Tissue Engineering and Regenerative Medicine is a proceedings volume which reflects papers presented at the 3rd bi-annual Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Stem Cells: Biology and Engineering it provides a complete overview of the papers from that meeting of international experts.

Stem Cells

Author : Anna M. Wobus
Publisher : Springer Science & Business Media
ISBN 13 : 354031265X
Total Pages : 414 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Stem Cells by : Anna M. Wobus

Download or read book Stem Cells written by Anna M. Wobus and published by Springer Science & Business Media. This book was released on 2006-01-31 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This hugely important volume presents in a single text many novel aspects of stem cell biology with respect to scientific endeavors and future applications. During the past few years, stem cell research has metamorphosed into distinct and specialized avenues of research. What makes this book unique is that it not only covers these varied areas of research, but examines in detail some of the key pharmacological issues that up to now have not been addressed in a single volume.

An Osteopathic Approach to Children

Author : Jane Elizabeth Carreiro
Publisher : Elsevier Health Sciences
ISBN 13 : 1455740985
Total Pages : 310 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis An Osteopathic Approach to Children by : Jane Elizabeth Carreiro

Download or read book An Osteopathic Approach to Children written by Jane Elizabeth Carreiro and published by Elsevier Health Sciences. This book was released on 2009-02-17 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Osteopathic Approach to Children presents a comprehensive general overview of pediatric medicine from an osteopathic perspective. The book is divided into two main parts. The first part discusses the normal development, physiology and anatomy of the body systems from birth to adulthood. The second part explores the conditions and diseases of childhood and outlines the rationale for osteopathic treatment for each disorder. Also, it presents clinical problems from the perspective of the interrelatedness of structure and function. This unique approach will make it an invaluable source of reference for all those interested in using an osteopathic approach to the treatment of children in their care. 2 new chapters, with new photographs. Fully updated and expanded of current chapters.