Author : Rafael Caputo Oliveira
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.:/5 (113 download)
Book Synopsis Prepartum CLA Or Postpartum Ammonium Lactate Supplementation Improves Blood Metabolite Profile and Lactation Performance in Transition Dairy Cows by : Rafael Caputo Oliveira
Download or read book Prepartum CLA Or Postpartum Ammonium Lactate Supplementation Improves Blood Metabolite Profile and Lactation Performance in Transition Dairy Cows written by Rafael Caputo Oliveira and published by . This book was released on 2019 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reduced feed intake during the transition period of dairy cows coupled with the high energy demand for milk production results in mobilization of fatty acids (FA) from adipose tissue. Excessive mobilization of FA can exceed the hepatic capacity for complete oxidation of FA, leading to metabolic disorders such as hyperketonemia (HYK) and fatty liver. The overall hypothesis of this dissertation was that metabolic disorders can be prevented by nutritional interventions that decrease supply of blood FA to the liver and/or increase the hepatic capacity for complete oxidation of FA. In the first experiment, we hypothesized that prepartum supplementation with conjugated linoleic acid (CLA) could be a strategy to decrease serum FA around calving, decrease prevalence of HYK, and improve lactation performance. Cows supplemented with CLA had greater milk protein and fat yield, resulting in an increased milk energy output. Cows fed with CLA had lower serum FA and [Beta]-hydroxybutyrate (BHB) immediately after calving compared to control. Prevalence of HYK reduced from 23% to 3% in CLA supplemented cows. In the second and third experiments, our hypothesis was that fermented ammoniated condensed whey (FACW) supplementation would increase the supply of gluconeogenic precursors to the liver, resulting in an improved postpartum plasma metabolic profile, lactation performance, and decreased liver triglyceride content. Postpartum FACW supplementation increased plasma glucose and insulin concentrations, and decreased those of FA and BHB. Incidence of HYK tended to be reduced from 60% to 37% in FACW supplemented cows. Cows supplemented with FACW also had lowered liver triglyceride content compared to control. Supplementation of FACW improved feed efficiency as accessed by measures of milk output relative to feed intake. Supplementation with FACW increased hepatic pyruvate carboxylase (PC) expression, but did not alter hepatic cytosolic phosphoenolpyruvate carboxykinase (PCK1), resulting in greater PC:PCK1 ratio. The latter suggests greater hepatic capacity for complete oxidation of FA in FACW-fed cows compared to control. Nutritional interventions presented in this dissertation improved metabolic health in postpartum dairy cows likely driven by decreased supply of FA to the liver and/or by increased hepatic capacity for complete oxidation of FA as suggested in the FACW study.