Author : F. Schmalzl
Publisher : Springer Science & Business Media
ISBN 13 : 3642674704
Total Pages : 305 pages
Book Rating : 4.6/5 (426 download)
Book Synopsis Preleukemia by : F. Schmalzl
Download or read book Preleukemia written by F. Schmalzl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical hematologists are frequently faced with the intriguing problem of agnogenic myelo dysplastic syndromes; these syndromes are peculiar in their failing or poor response to therapy and in that they frequently terminate in acute leukemia. An international symposium held in Innsbruck in 1978 was dedicated to clinical and pathophysiologic aspects of the preleukemic syndromes. This monograph consists of articles that correspond to the papers presented at the symposium and of the edited discussions. It was the aim of the symposium and of this monograph to outline comprehensively the pathophysiologic background of the preleukemic syndromes and to summarize the present information about their clinical management. The first part of the monograph covers that pathology of these disorders: Disturbed maturation and proliferation of the hemopoietic cells are the causes of cyto penias, of structural and ultrastructural anomalies, and of enzymatic and functional defects. Further articles are concerned with the evaluation of these features and of chromosome anomalies as possible tools for the diagnostic and prognostic classification of myelodysplasias. Pathogenetic data and immunologic considerations form the rationale for therapeutic ap proaches. F. Schmalzl K.-P. Hellriegel v Contents K.-P. Hellriegel and F. Schmalzl Preleukemia: Definition and Classification ... H. Heirnpel Conventional Morphological Examination of Blood and Bone Marrow Cells in the Diagnosis of Preleukemic Syndromes ... 4 C. Peschle Pure Red Cell Aplasia Type III: Progression to Acute Myeloid Leukemia and Absence of the IgG Inhibitor to Erythropoiesis ... 12 Discussion ... '. ... 14 ... I. Fohlmeister, H.E. Schaefer, K.-P. Hellriegel, and R.