Predicting High-Risk Individuals for Common Diseases Using Multi-Omics and Epidemiological Data

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Publisher : Frontiers Media SA
ISBN 13 : 2889714594
Total Pages : 198 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Predicting High-Risk Individuals for Common Diseases Using Multi-Omics and Epidemiological Data by : Lu Zhang

Download or read book Predicting High-Risk Individuals for Common Diseases Using Multi-Omics and Epidemiological Data written by Lu Zhang and published by Frontiers Media SA. This book was released on 2021-10-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multi-Omics Approaches to Study Signaling Pathways

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Publisher : Frontiers Media SA
ISBN 13 : 2889661253
Total Pages : 154 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multi-Omics Approaches to Study Signaling Pathways by : Jyoti Sharma

Download or read book Multi-Omics Approaches to Study Signaling Pathways written by Jyoti Sharma and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Evolution of Translational Omics

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Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Rare Diseases Epidemiology: Update and Overview

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Publisher : Springer
ISBN 13 : 3319671448
Total Pages : 675 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Rare Diseases Epidemiology: Update and Overview by : Manuel Posada de la Paz

Download or read book Rare Diseases Epidemiology: Update and Overview written by Manuel Posada de la Paz and published by Springer. This book was released on 2017-12-06 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of rare diseases research and orphan products development continue to expand with more products in research and development status. In recent years, the role of the patient advocacy groups has evolved into a research partner with the academic research community and the bio-pharmaceutical industry. Unique approaches to research and development require epidemiological data not previously available to assist in protocol study design and patient recruitment for clinical trials required by regulatory agencies prior to approval for access by patents and practicing physicians.

Precision Medicine and Artificial Intelligence

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Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 300 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Precision Medicine and Artificial Intelligence by : Michael Mahler

Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Identifying the Key Pathogenic Factors of Neurological Disorders by Integrating Multi-omics Data

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Publisher : Frontiers Media SA
ISBN 13 : 2832507867
Total Pages : 165 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identifying the Key Pathogenic Factors of Neurological Disorders by Integrating Multi-omics Data by : Andrea Legati

Download or read book Identifying the Key Pathogenic Factors of Neurological Disorders by Integrating Multi-omics Data written by Andrea Legati and published by Frontiers Media SA. This book was released on 2022-11-30 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Epidemiology

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Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Artificial Intelligence in Healthcare

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Publisher : Academic Press
ISBN 13 : 0128184396
Total Pages : 385 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Artificial Intelligence in Healthcare by : Adam Bohr

Download or read book Artificial Intelligence in Healthcare written by Adam Bohr and published by Academic Press. This book was released on 2020-06-21 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Genomics in Precision Medicine

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Publisher : Delve Publishing
ISBN 13 : 9781774073445
Total Pages : 290 pages
Book Rating : 4.0/5 (734 download)

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Book Synopsis Genomics in Precision Medicine by : Shiv Sanjeevi

Download or read book Genomics in Precision Medicine written by Shiv Sanjeevi and published by Delve Publishing. This book was released on 2019-11 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics in Precision Medicine makes the people aware about the field of genomics and that of precision medicine, by taking the readers through all the details related to genomics and precision medicine. It also updates the readers about the various innovations that have taken place in the field of precision medicine and discusses the path that is to be followed further. Also discussed in the book is a review on the relation between the precision medicine and the mutations that drive it, delving on the various computational methods and conformational principles for the detection of the factors that drive cancer. It also discusses the various genetic mutations and epigenetic modifications and goes on to explore the various benefits and harms in the research on precision medicine.

Artificial Intelligence in Behavioral and Mental Health Care

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Publisher : Academic Press
ISBN 13 : 0128007923
Total Pages : 309 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Artificial Intelligence in Behavioral and Mental Health Care by : David D. Luxton

Download or read book Artificial Intelligence in Behavioral and Mental Health Care written by David D. Luxton and published by Academic Press. This book was released on 2015-09-10 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence in Behavioral and Mental Health Care summarizes recent advances in artificial intelligence as it applies to mental health clinical practice. Each chapter provides a technical description of the advance, review of application in clinical practice, and empirical data on clinical efficacy. In addition, each chapter includes a discussion of practical issues in clinical settings, ethical considerations, and limitations of use. The book encompasses AI based advances in decision-making, in assessment and treatment, in providing education to clients, robot assisted task completion, and the use of AI for research and data gathering. This book will be of use to mental health practitioners interested in learning about, or incorporating AI advances into their practice and for researchers interested in a comprehensive review of these advances in one source. Summarizes AI advances for use in mental health practice Includes advances in AI based decision-making and consultation Describes AI applications for assessment and treatment Details AI advances in robots for clinical settings Provides empirical data on clinical efficacy Explores practical issues of use in clinical settings

Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease

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Publisher : National Academies Press
ISBN 13 : 0309462568
Total Pages : 335 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease by : National Academies of Sciences, Engineering, and Medicine

Download or read book Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-12-21 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1938 and 1941, nutrient intake recommendations have been issued to the public in Canada and the United States, respectively. Currently defined as the Dietary Reference Intakes (DRIs), these values are a set of standards established by consensus committees under the National Academies of Sciences, Engineering, and Medicine and used for planning and assessing diets of apparently healthy individuals and groups. In 2015, a multidisciplinary working group sponsored by the Canadian and U.S. government DRI steering committees convened to identify key scientific challenges encountered in the use of chronic disease endpoints to establish DRI values. Their report, Options for Basing Dietary Reference Intakes (DRIs) on Chronic Disease: Report from a Joint US-/Canadian-Sponsored Working Group, outlined and proposed ways to address conceptual and methodological challenges related to the work of future DRI Committees. This report assesses the options presented in the previous report and determines guiding principles for including chronic disease endpoints for food substances that will be used by future National Academies committees in establishing DRIs.

Preterm Birth

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Publisher : National Academies Press
ISBN 13 : 030910159X
Total Pages : 791 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Preterm Birth by : Institute of Medicine

Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.

Disease Pathways

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Publisher : Elsevier
ISBN 13 : 0128170875
Total Pages : 732 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Disease Pathways by : Anastasia P. Nesterova

Download or read book Disease Pathways written by Anastasia P. Nesterova and published by Elsevier. This book was released on 2019-10-18 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. Disease pathways are based on computational models from Elsevier’s Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.

Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine

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Publisher : Frontiers Media SA
ISBN 13 : 2889635546
Total Pages : 393 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine by : Tao Zeng

Download or read book Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine written by Tao Zeng and published by Frontiers Media SA. This book was released on 2020-03-30 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in China Epidemiology

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Publisher : Springer Nature
ISBN 13 : 9811921997
Total Pages : 478 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Progress in China Epidemiology by : Dong-Qing Ye

Download or read book Progress in China Epidemiology written by Dong-Qing Ye and published by Springer Nature. This book was released on 2023-01-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to show the great achievements and valuable experience of Chinese public health practices and epidemiological theories and methods. It is conducive to expanding medical workers’ practical ability of disease prevention and control, and to bridging the gap between clinical medicine and public health. In part 1, it introduces the progress in epidemiology of 10 infectious diseases. In part 2, it covers 11 non-communicable diseases. The research method and prediction modelling and public health ethics are discussed in the 11 chapters of part 3. The contributors include epidemiologists and public health experts, as well as more clinicians, mathematicians, sociologists, philosophers (ethicists), bioinformatics and so on. Among them, there are not only professors from universities, but also researchers from scientific research institutes, and experts in the front line of disease prevention and control.

Artificial Intelligence and Bioinformatics Applications for Omics and Multi-Omics Studies

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Publisher : Frontiers Media SA
ISBN 13 : 2832544452
Total Pages : 160 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Artificial Intelligence and Bioinformatics Applications for Omics and Multi-Omics Studies by : Angelo Facchiano

Download or read book Artificial Intelligence and Bioinformatics Applications for Omics and Multi-Omics Studies written by Angelo Facchiano and published by Frontiers Media SA. This book was released on 2024-02-07 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Accelerated Path to Cures

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Publisher : Springer
ISBN 13 : 3319732382
Total Pages : 82 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Accelerated Path to Cures by : Josep Bassaganya-Riera

Download or read book Accelerated Path to Cures written by Josep Bassaganya-Riera and published by Springer. This book was released on 2018-04-25 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures.