Potential Protective Effects Of Metformin On Ocular Complications In Patients With Type 2 Diabetes

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Potential Protective Effects of Metformin on Ocular Complications in Patients with Type 2 Diabetes

Author : Jasna Kusturica
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Potential Protective Effects of Metformin on Ocular Complications in Patients with Type 2 Diabetes by : Jasna Kusturica

Download or read book Potential Protective Effects of Metformin on Ocular Complications in Patients with Type 2 Diabetes written by Jasna Kusturica and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus (DM) as a chronic condition is a growing global problem. Its numerous complications, including ocular diseases, affect patients,Äô quality and length of life. Metformin is an effective, safe, and inexpensive first-line pharmacotherapy for type 2 diabetes (T2D). The current evidence indicates metformin,Äôs multiple sites of action and multiple molecular mechanisms leading to its beneficial impact on metabolism, inflammation, oxidative stress, aging, as well as to its cardiovascular, neurological, bone, and antiproliferative properties. These impacts are the result of its acting on adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. Limited data suggest the protective role of metformin on microvascular ocular complications, including retinopathy, glaucoma, and age-related macular degeneration in patients with T2D.¬†However, to confirm its mentioned protective and therapeutic effects, more large, randomized, double-blind, and placebo-controlled clinical studies are needed.

Metformin

Author : Anca Pantea Stoian
Publisher : BoD – Books on Demand
ISBN 13 : 1838804277
Total Pages : 244 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Metformin by : Anca Pantea Stoian

Download or read book Metformin written by Anca Pantea Stoian and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book “Metformin” aims to bring to light new concepts and trends related to the many metformin therapeutic features. After a history of over 60 years, with moments of decline and spectacular returns, metformin can now be regarded as a universal panacea, the valences of its therapeutics being increasingly appreciated, both in the background treatment of diabetes and pre-diabetes, but also in reproductive pathology, cancer, cardiovascular disease, and antiageing. In this respect, the mechanisms of action and the pharmacodynamics of metformin seem to be incompletely known, a number of current studies have revealed new action valences.

Disease Control Priorities, Third Edition (Volume 5)

Author : Dorairaj Prabhakaran
Publisher : World Bank Publications
ISBN 13 : 1464805202
Total Pages : 948 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 5) by : Dorairaj Prabhakaran

Download or read book Disease Control Priorities, Third Edition (Volume 5) written by Dorairaj Prabhakaran and published by World Bank Publications. This book was released on 2017-11-17 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Pathogenesis of Fibrosis

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (788 download)

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Book Synopsis Pathogenesis of Fibrosis by :

Download or read book Pathogenesis of Fibrosis written by and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vitreoretinal Surgery

Author : Sandeep Saxena
Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN 13 : 9350256819
Total Pages : 459 pages
Book Rating : 4.3/5 (52 download)

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Book Synopsis Vitreoretinal Surgery by : Sandeep Saxena

Download or read book Vitreoretinal Surgery written by Sandeep Saxena and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2012-03-29 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of this book lies in the quality and expertise of the text chapters contributed by multiple international experts across the globe. Clearly written by the contributors providing a global perspective about the subject. Attempts to update the state-of-the-art vitreoretinal surgery in a lucid, authoritative and well-illustrated manner. Detailed reference lists following each chapter provide extensive background support for the text. Outstanding illustrations combined with excellent schematic drawings, beautiful clinical photographs, fluorescein angiograms, and OCT images. Illustrations.

PanVascular Medicine

Author : Peter Lanzer
Publisher : Springer
ISBN 13 : 9783642370779
Total Pages : 5004 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis PanVascular Medicine by : Peter Lanzer

Download or read book PanVascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2015-03-30 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.

Metformin: Beyond Diabetes

Author : Frederic Bost
Publisher : Frontiers Media SA
ISBN 13 : 2889634078
Total Pages : 134 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Metformin: Beyond Diabetes by : Frederic Bost

Download or read book Metformin: Beyond Diabetes written by Frederic Bost and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes Mellitus in Children

Author : Mark A. Sperling
Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)

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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antioxidant-Antidiabetic Agents and Human Health

Author : Oluwafemi Oguntibeju
Publisher : BoD – Books on Demand
ISBN 13 : 9535112155
Total Pages : 384 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Antioxidant-Antidiabetic Agents and Human Health by : Oluwafemi Oguntibeju

Download or read book Antioxidant-Antidiabetic Agents and Human Health written by Oluwafemi Oguntibeju and published by BoD – Books on Demand. This book was released on 2014-02-05 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.

The Diabetic Neuropathies

Author : National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports
Publisher :
ISBN 13 :
Total Pages : 12 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis The Diabetic Neuropathies by : National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports

Download or read book The Diabetic Neuropathies written by National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports and published by . This book was released on 1978 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Diabetes Mellitus

Author : Leonid Poretsky
Publisher : Springer Science & Business Media
ISBN 13 : 9781402071140
Total Pages : 788 pages
Book Rating : 4.0/5 (711 download)

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Book Synopsis Principles of Diabetes Mellitus by : Leonid Poretsky

Download or read book Principles of Diabetes Mellitus written by Leonid Poretsky and published by Springer Science & Business Media. This book was released on 2002 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.

Intravitreal Steroids

Author : Albert J. Augustin
Publisher : Springer
ISBN 13 : 3319144871
Total Pages : 113 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Intravitreal Steroids by : Albert J. Augustin

Download or read book Intravitreal Steroids written by Albert J. Augustin and published by Springer. This book was released on 2015-02-19 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.

Type 2 Diabetes

Author : Anca Pantea Stoian
Publisher : BoD – Books on Demand
ISBN 13 : 1838819037
Total Pages : 442 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Type 2 Diabetes by : Anca Pantea Stoian

Download or read book Type 2 Diabetes written by Anca Pantea Stoian and published by BoD – Books on Demand. This book was released on 2021-09-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.

Clinical Case Studies for the Family Nurse Practitioner

Author : Leslie Neal-Boylan
Publisher : John Wiley & Sons
ISBN 13 : 1118277856
Total Pages : 432 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Clinical Case Studies for the Family Nurse Practitioner by : Leslie Neal-Boylan

Download or read book Clinical Case Studies for the Family Nurse Practitioner written by Leslie Neal-Boylan and published by John Wiley & Sons. This book was released on 2011-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use.

Mitochondrial Dysfunction

Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

The Cohen Diabetic Rat

Author : Aharon Mordechai Cohen
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cohen Diabetic Rat by : Aharon Mordechai Cohen

Download or read book The Cohen Diabetic Rat written by Aharon Mordechai Cohen and published by . This book was released on 1990 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxford Handbook of Ophthalmology

Author : Alastair K. O. Denniston
Publisher : Oxford University Press
ISBN 13 : 019252674X
Total Pages : 1249 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Oxford Handbook of Ophthalmology by : Alastair K. O. Denniston

Download or read book Oxford Handbook of Ophthalmology written by Alastair K. O. Denniston and published by Oxford University Press. This book was released on 2018-05-24 with total page 1249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and updated throughout, the fourth edition of the Oxford Handbook of Ophthalmology now includes free access to the ophthalmic online media bank, a selection of high-quality clinical images and videos for a wide breadth of key ophthalmic diseases. Clear, concise, and practical, this handbook provides immediate access to the detailed clinical information you need, in casualty, clinic, theatre, and on the wards. The core of the book comprises a systematic synopsis of ophthalmic disease directed towards diagnosis, interim assessment, and ongoing management. Assessment boxes for common clinical conditions and algorithms for important clinical presentations illustrate this practical approach. The information is easily accessible, presented in a clear format with areas of importance highlighted. Key sections for the trainee include: Clinical Skills, Aids to Diagnosis, Investigations and their Interpretation, Perioperative Care, Theatre Notes and Therapeutics. The wider practise of eye-care is supported by expanded chapters on Refractive Ophthalmology, Vision in Context, Evidence Based Ophthalmology and Resources for Ophthalmologists. Now including newer treatments across a range of specialities such as SMILE, gene-therapy and retinal prostheses, as well as greater emphasis on the evidence underlying current clinical practice and guidelines, this handbook has never been more essential for all those working in eye-care. Whether you want to learn about patient-reported outcomes, identify a surgical instrument, interpret a statistical test, or diagnose and treat ophthalmic emergencies, you will find it here. Whatever your role in caring for patients with eye disease: ophthalmologist, optometrist, orthoptist, ophthalmic nurse, or other health profession - discover for yourself why this handbook has become the 'go-to' resource for tens of thousands of eye-care professionals around the world.