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Author : Athina Markou
Publisher :
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.:/5 (318 download)
Download or read book Post-cocaine Anhedonia written by Athina Markou and published by . This book was released on 1991 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Domenic A. Ciraulo
Publisher : Springer Science & Business Media
ISBN 13 : 1603274359
Total Pages : 432 pages
Book Rating : 4.6/5 (32 download)
Download or read book Pharmacotherapy of Depression written by Domenic A. Ciraulo and published by Springer Science & Business Media. This book was released on 2010-12-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and state of the art, the second edition of Pharmacotherapy of Depression offers major revisions of every chapter and the addition of new chapters by expert contributors. The first chapter reviews the neurobiology of depression, which lays the groundwork for understanding the mechanisms of action of antidepressants. In the next chapter, a review of the general principles guiding the diagnosis and medication treatment of unipolar depression is provided. The clinical pharmacology of antidepressants is reviewed in some detail, supplemented by tables that provide information on dosing, indications, and metabolism. Augmentation strategies are reviewed, including the use of non-traditional agents. The chapters that follow next address the use of antidepressants in special populations, such as the elderly and depressed individuals with psychosis, bipolar disorder, substance abuse, and post traumatic stress disorder. The complex issues involving the diagnosis and treatment of depression during pregnancy is thoroughly reviewed in Chapter 8 and provides a synthesis of the scientific literature in the area, one that is noted for contradictory and controversial findings, as well as guidelines for prescribing. The next chapter then provides an overview of the treatment of depression in the pediatric population, highlighting clinical concerns such as suicide risk. The book concludes with two chapters at the interface of medicine and psychiatry in the treatment of mood disorders: managing depression in primary care settings and depression associated with medical illnesses. The outstanding clinician-scientists who have contributed to this volume are all leaders in their fields and represent a broad spectrum of renowned institutions. A timely contribution to the literature, The Pharmacotherapy of Depression, Second Edition, offers busy clinicians from many disciplines a strong scientific foundation that seamlessly transitions into practical recommendations for clinical practice. The result is another gold-standard guide to the safe and effective use of the latest antidepressant medications.
Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0123869595
Total Pages : 351 pages
Book Rating : 4.1/5 (238 download)
Download or read book Drugs, Addiction, and the Brain written by George F. Koob and published by Academic Press. This book was released on 2014-07-12 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction
Author : Ronald P. Hammer, Jr.
Publisher : CRC Press
ISBN 13 : 9780849383113
Total Pages : 286 pages
Book Rating : 4.3/5 (831 download)
Download or read book The Neurobiology of Cocaine written by Ronald P. Hammer, Jr. and published by CRC Press. This book was released on 1995-07-17 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Representing the latest data from active research groups, The Neurobiology of Cocaine is designed to educate students and inform experts in a rapidly changing field. This volume presents current research regarding the mechanisms of cocaine's action in the brain. Recent developments of cellular, molecular, and brain imaging methods provide new evidence that chemical and molecular substrates underlie cocaine reinforcement, dependence, and withdrawal. This book explores the biological bases of such effects, describing the brain circuits affected by cocaine, neuroendocrine and neurophysiological actions of cocaine, neurochemistry and pharmacology of cocaine, and cocaine effects on signal transduction, gene expression, and protein phosphorylation. This up-to-date text also describes the recently cloned class of neurotransporters affected by cocaine and characterizes their interaction with the drug. These reports focus on the effects of chronic exposure and subsequent withdrawal, which are differentiated from acute cocaine actions. Thus, they provide information on brain mechanisms likely active during long-term use and abuse in humans. Such commonalities are illustrated by a discussion of cocaine action in the human brain as visualized by positron emission tomography. This volume is a must for anyone interested in the mechanisms underlying cocaine abuse.
Author : Michael Koch
Publisher : World Scientific
ISBN 13 : 1783260068
Total Pages : 426 pages
Book Rating : 4.7/5 (832 download)
Download or read book Animal Models Of Neuropsychiatric Diseases written by Michael Koch and published by World Scientific. This book was released on 2006-05-11 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry. Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases. The book is specifically written with the research-oriented reader in mind — both in academia and the pharmaceutical industry. It contains first-hand information on how to design viable animal models for Alzheimer's disease, epilepsy, Huntington's disease, Parkinson's disease, addiction, depression, fear and anxiety, and schizophrenia. Each chapter also critically discusses the limitations of the animal experimental approach towards an understanding of human neuropsychiatric disorders.The book is an essential source of reference for researchers who seek to successfully continue and elaborate the experimental work that will finally lead to a better understanding of the neurobiological basis of the diseases, as well as to an improvement of both diagnosis and therapy.
Author : Everett Ellinwood
Publisher : Springer
ISBN 13 : 9781468430899
Total Pages : 0 pages
Book Rating : 4.4/5 (38 download)
Download or read book Cocaine and Other Stimulants written by Everett Ellinwood and published by Springer. This book was released on 2012-12-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a collection of articles that were presented at a conference on contemporary issues in stimulant research held at Duke University Medical Center, November 10-12, 1975.
Author : Allan Tasman
Publisher : John Wiley & Sons
ISBN 13 : 1118845498
Total Pages : 2759 pages
Book Rating : 4.1/5 (188 download)
Download or read book Psychiatry written by Allan Tasman and published by John Wiley & Sons. This book was released on 2015-01-29 with total page 2759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a new Fourth Edition, Psychiatry remains the leading reference on all aspects of the current practice and latest developments in psychiatry. From an international team of recognised expert editors and contributors, Psychiatry provides a truly comprehensive overview of the entire field of psychiatry in 132 chapters across two volumes. It includes two new sections, on psychosomatic medicine and collaborative care, and on emergency psychiatry, and compares Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD10) classifications for every psychiatric disorder. Psychiatry, Fourth Edition is an essential reference for psychiatrists in clinical practice and clinical research, residents in training, and for all those involved in the treatment psychiatric disorders. Includes a a companion website at www.tasmanpsychiatry.com featuring PDFs of each chapter and downloadable images
Author : Allan Tasman
Publisher : John Wiley & Sons
ISBN 13 : 1118845471
Total Pages : 2765 pages
Book Rating : 4.1/5 (188 download)
Download or read book Psychiatry, 2 Volume Set written by Allan Tasman and published by John Wiley & Sons. This book was released on 2015-03-30 with total page 2765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a new Fourth Edition, Psychiatry remains the leading reference on all aspects of the current practice and latest developments in psychiatry. From an international team of recognised expert editors and contributors, Psychiatry provides a truly comprehensive overview of the entire field of psychiatry in 132 chapters across two volumes. It includes two new sections, on psychosomatic medicine and collaborative care, and on emergency psychiatry, and compares Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD10) classifications for every psychiatric disorder. Psychiatry, Fourth Edition is an essential reference for psychiatrists in clinical practice and clinical research, residents in training, and for all those involved in the treatment psychiatric disorders. Includes a a companion website at www.tasmanpsychiatry.com featuring PDFs of each chapter and downloadable images
Author : Robert A. McArthur
Publisher : Academic Press
ISBN 13 : 0080920403
Total Pages : 426 pages
Book Rating : 4.0/5 (89 download)
Download or read book Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders written by Robert A. McArthur and published by Academic Press. This book was released on 2009-02-24 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reward Deficit Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as alcohol dependence, nicotine dependence, heroin and cocaine addiction, obesity, and gambling and impulse control disorders. Reward Deficit Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. Reward Deficit Disorders also has a section dedicated to the specifics of the regulatory aspects to abuse liability testing. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the third volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Neurological Disorders is available for purchase individually.
Author : George F. Koob
Publisher : Elsevier
ISBN 13 : 0080497373
Total Pages : 503 pages
Book Rating : 4.0/5 (84 download)
Download or read book Neurobiology of Addiction written by George F. Koob and published by Elsevier. This book was released on 2005-11-11 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.· Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching
Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0128167955
Total Pages : 280 pages
Book Rating : 4.1/5 (281 download)
Download or read book Introduction to Addiction written by George F. Koob and published by Academic Press. This book was released on 2019-06-11 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. - Provides neurobiological theories on how addiction works - Explains addiction cycle stages of binge, withdrawal and anticipation - Reviews the role of dopamine and the frontal cortex in addiction - Discusses the neurocircuitry of reward and stress - Includes animal models and neuroadaptational views on addiction
Author : J. Descotes
Publisher : Elsevier
ISBN 13 : 0080534228
Total Pages : 859 pages
Book Rating : 4.0/5 (85 download)
Download or read book Human Toxicology written by J. Descotes and published by Elsevier. This book was released on 1996-09-02 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: This excellent volume was designed and edited with two major ideas in mind: firstly, the field of clinical toxicology is changing and an acknowledgement of these changes is warranted; secondly, no comprehensive compilation of recently published case reports of, and clinical studies on, human poisonings is available, which is in sharp contrast to the closely related field of drug-induced side-effects.The book focusses on issues of recent concern, or issues poorly documented in the past. It is important that clinical toxicologists gain a better knowledge of all the available techniques of toxicological analysis. A better understanding of the way a sound interpretation of results should be conducted for the benefit of the patient's management, and a comprehensive set of data on the kinetics of the most common pharmaceutical drugs and many chemicals is required.Human Toxicology is a timely reference work which will be welcomed by a broad audience of toxicology professionals.
Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0128169915
Total Pages : 264 pages
Book Rating : 4.1/5 (281 download)
Download or read book Psychostimulants written by George F. Koob and published by Academic Press. This book was released on 2020-05-05 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. - Highlights recent advances in psychostimulant addiction - Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction - Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics
Author : Helmut Buschmann
Publisher : John Wiley & Sons
ISBN 13 : 3527310584
Total Pages : 1292 pages
Book Rating : 4.5/5 (273 download)
Download or read book Antidepressants, Antipsychotics, Anxiolytics, 2 Volume Set written by Helmut Buschmann and published by John Wiley & Sons. This book was released on 2007-04-16 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antidepressants and related psychiatric drugs are the most important prescription drugs worldwide, accounting for a market volume of 20 billion US$ per year. This handbook provides a complete and detailed overview of all currently available psychiatric drugs, covering more than 250 different compounds. Particular features include: * the most important information on the chemistry, pharmacology and therapeutic use of a given drug * a special layout with margin notes and compound structures allowing for quick and easy access to the desired information Written by drug developers from the pharmaceutical industry, novel drugs currently under development and new methods of treatment are listed side by side with classical drugs, allowing a direct comparison of traditional and innovative therapeutic approaches.
Author : Rafael Maldonado
Publisher : Springer Science & Business Media
ISBN 13 : 3662222183
Total Pages : 212 pages
Book Rating : 4.6/5 (622 download)
Download or read book Neurobiological Mechanisms of Opiate Withdrawal written by Rafael Maldonado and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some general aspects of opiate dependence are described in a first section including a brief historical description and an explanation of the different models currently used to investigate opiate dependence. The neurobiological bases of opiate withdrawal are detailed in a second section, which particularly emphasizes the neurophysiological adaptative changes, the processes of homologous and heterologous regulation, and the role played by different brain structures and several endogenous peptides acting as antiopiates. The last part reports several basic aspects more directly related to the clinical perspectives of opiate dependence, such as the new expectations in the treatment of opiate withdrawal or the relationships between sensitization, tolerance and withdrawal.
Author : Antonio Noronha
Publisher :
ISBN 13 :
Total Pages : 586 pages
Book Rating : 4.3/5 ( download)
Download or read book Review of NIAAA's Neuroscience and Behavioral Research Portfolio written by Antonio Noronha and published by . This book was released on 2000 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.:/5 (3 download)
Download or read book Special Report to the U.S. Congress on Alcohol and Health from the Secretary of Health and Human Services written by and published by . This book was released on 2000 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
