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Positron Emission Tomography In Clinical Research Tracer Modelling And Radioreceptors
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Book Synopsis Positron Emission Tomography in Clinical Research: Tracer Modelling and Radioreceptors by : C. Beckers
Download or read book Positron Emission Tomography in Clinical Research: Tracer Modelling and Radioreceptors written by C. Beckers and published by Springer Science & Business Media. This book was released on 1989-07-31 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a workshop held in Brussels, Belgium within the framework of the European Community Medical and Public Health Research
Book Synopsis Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects by : G. Stöcklin
Download or read book Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects written by G. Stöcklin and published by Springer Science & Business Media. This book was released on 1993-06-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals. Of the several hundred products which have been labelled with positron emitters during the past two decades about 35 are presently considered to be of major interest. The time for a state-of-the-art review is right, since this field has advanced over the past fifteen years to reach a level where guidelines can now be suggested. Chapters of this book deal with each of the main methodological aspects of the chemistry needed to develop an effective radiopharmaceutical, namely radionuclide production, automation and metabolite analysis. A further chapter on QA/QC is written by a broadly-based expert group and is meant to provide a guideline and a base for future monographs and regulations on major PET radiopharmaceuticals of today. This book will help the increasing numbers of scientists who are now entering the field of PET to appreciate the methodological aspects that are normally addressed by chemists in relation to PET radiopharmaceuticals; it provides many useful practical guidelines and will promote early success in their own endeavours, since these will often necessarily begin by establishing chemical methodology of the kind discussed here.
Book Synopsis PET Studies on Amino Acid Metabolism and Protein Synthesis by : B.M. Mazoyer
Download or read book PET Studies on Amino Acid Metabolism and Protein Synthesis written by B.M. Mazoyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? These questions have been addressed for a long time and no satisfactory answer has yet been given. This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.
Book Synopsis Nuclear and Radiochemistry by : Karl Heinrich Lieser
Download or read book Nuclear and Radiochemistry written by Karl Heinrich Lieser and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of the best-selling handbook gives a complete and concise description of the latest knowledge on nuclear and radiochemistry as well as their applications in the various fields of science. It is based on over 40 years experience in teaching courses and research. The book is aimed at all researchers seeking sound knowledge about the properties of matter, whether chemists, physicists, medical doctors, mineralogists or biologists. All of them will find this a valuable source of information. Research in radiochemistry includes: Study of radioactive matter in nature, investigation of radioactive transmutations, chemistry of radioelements etc. Applications include: Radionuclides in geo- and cosmochemistry, dating by nuclear methods, radioanalysis, Mossbauer spectroscopy and related methods, behavior of natural and man-made radionuclides in the environment, dosimetry and radiation protection. All the subjects are presented clearly and comprehensibly, and in a logical sequence, avoiding detailed derivations of equations. The relevant information is compiled in tables and the recent edition of the multi-colored Karlsruhe 'Chart of the Nuclides' has also been included. Clearly a standard work by an author with extensive experience in research and teaching.
Book Synopsis Brain Dopaminergic Systems: Imaging with Positron Tomography by : J.C Baron
Download or read book Brain Dopaminergic Systems: Imaging with Positron Tomography written by J.C Baron and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J.C. Baron D. Comar L. Farde J.L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.
Book Synopsis Clinical Application of Radiolabelled Platelets by : C. Kessler
Download or read book Clinical Application of Radiolabelled Platelets written by C. Kessler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.
Author :Francisco José H.N. Braga Publisher :Springer Science & Business Media ISBN 13 :9781402071911 Total Pages :282 pages Book Rating :4.0/5 (719 download)
Book Synopsis Nuclear Medicine in Tropical and Infectious Diseases by : Francisco José H.N. Braga
Download or read book Nuclear Medicine in Tropical and Infectious Diseases written by Francisco José H.N. Braga and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: "More than half of the world's population is at risk of the tropical diseases malaria, leprosy, schistosomiasis, lymphatic filariasis, onchocerciasis, Chagas' disease, African trypanosomiasis and leishmaniasis and half a billion are infected with at least one of these diseases". J. H. F. Remme, World Health Organisation, 1993. "If it is true that science is not limited by frontiers and all research Institutions then belong to mankind, so it is natural for each Institution to be responsible for the problems of those who live in the geographic area under its influence. There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology. It is the duty of each Institution to study the particular aspects concerning its geographic region, as missing links of the chain of universal knowledge may be found there." H. L. de Oliveira, fonner Rector of the University ofSiio Paulo, 1967. "Nuclear Medicine is cost effective, especially in the developing countries. ( ... ).
Book Synopsis Nuclear and Radiochemistry by : Jens-Volker Kratz
Download or read book Nuclear and Radiochemistry written by Jens-Volker Kratz and published by John Wiley & Sons. This book was released on 2013-08-15 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this classic in the field is completely updated and revised with approximately 30% new content so as to include the latest developments. The handbook and ready reference comprehensively covers nuclear and radiochemistry in a well-structured and readily accessible manner, dealing with the theory and fundamentals in the first half, followed by chapters devoted to such specific topics as nuclear energy and reactors, radiotracers, and radionuclides in the life sciences. The result is a valuable resource for both newcomers as well as established scientists in the field.
Book Synopsis Radioiodination: Theory, Practice, and Biomedical Applications by : Mrinal K. Dewanjee
Download or read book Radioiodination: Theory, Practice, and Biomedical Applications written by Mrinal K. Dewanjee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect by : M. Diksic
Download or read book Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect written by M. Diksic and published by CRC Press. This book was released on 2021-09-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1991, this book covers three major areas essential to in vivo biochemical studies with PET and SPECT: synthesis of radiopharmaceuticals, biological modeling, and clinical applications. The book emphasizes advances in the synthesis of radiopharmaceuticals used in PET and SPECT studies of brain flow and oxidatative metabolism, in addition to biological modeling. The most widely used 2-deoxyglucose/2-fluorodeoxyglucose models are discussed, as well as models used in the quantitation of brain receptors. Other topics include a possible model for converting 6-[18F] fluorodopa images into the quantitative rate of dopamine synthesis, evaluations of technetium- and iodine-labeled blood flow tracers, and possibilities for using SPECT to measure other pathophysiological variables. This book will be a valuable reference source to students and specialists interested in these in vivo measurements.
Book Synopsis Brain Dopaminergic Systems by : European Economic Community
Download or read book Brain Dopaminergic Systems written by European Economic Community and published by Springer Science & Business Media. This book was released on 1991 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: .the book is most valuable for those who are starting to study the brain dopaminergic system and are considering PET as a tool.' Nuclear Medicine 19:9 1992
Download or read book General Anatomy written by Leondes and published by CRC Press. This book was released on 1997-11-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of anatomy systems elements and diagnosis has been revolutionized by new techniques in powerful computations, image processing, and modalities such as computer-aided tomography (CAT) and magnetic resonance, among others. It is therefore an appropriate topic to be included in this series that studies the marriage of computer capabilities and medical imaging, which exemplifies a significant manifestation of relatively recent, valuable technologies known as the second industrial revolution. A few of the issues studied in this book are boundary detection and the applications of image segmentation; functional imaging; the registration of scans of patients undergoing cranio-maxillo-facial surgery; image processing techniques for the noninvasive alternative to needle biopsy for patients with liver disease; knowledge-based diagnosis support for mammogram image analysis; and input function monitors, necessary to quantify physiologic function. This book clearly reveals the effectivene
Book Synopsis Subject Guide to Books in Print by :
Download or read book Subject Guide to Books in Print written by and published by . This book was released on 2001 with total page 3054 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulative Book Index written by and published by . This book was released on 1990 with total page 2280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.
Download or read book Pain written by and published by . This book was released on 1993-07 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:
