Polymeric Nanoparticles For The Treatment Of Solid Tumors

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Polymeric nanoparticles for the treatment of solid tumors

Author : Santwana Padhi
Publisher : Springer Nature
ISBN 13 : 3031148487
Total Pages : 515 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Polymeric nanoparticles for the treatment of solid tumors by : Santwana Padhi

Download or read book Polymeric nanoparticles for the treatment of solid tumors written by Santwana Padhi and published by Springer Nature. This book was released on 2022-11-14 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles

Development of Polymeric Therapeutic Nanoparticles

Author : Kristen S. Wek
Publisher :
ISBN 13 :
Total Pages : 46 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Development of Polymeric Therapeutic Nanoparticles by : Kristen S. Wek

Download or read book Development of Polymeric Therapeutic Nanoparticles written by Kristen S. Wek and published by . This book was released on 2017 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: To improve current chemotherapy treatments, there is a need for non-harmful imaging modalities that can serve to treat and longitudinally monitor patient tumors. Fluorine MRI provides a safe tracer technology that allows recognition of the size and anatomical location of the tumor. Polymeric nanoparticles were designed with an azide termini, high fluorine content for MRI, self-assembly, and minimal toxicity. Copolymers were polymerized using fluorinated and PEG monomers and shown to self-assemble to colloidal nanoparticles for passive tumor targeting. To improve the imaging properties of the nanoparticle, a library of copolymers, with various molecular weights and compositions, were synthesized to compare imaging efficiency. The signal properties remained consistent between the different polymer compositions indicating a need for external modalities that can be conjugated to the azide handle. These studies indicate that development of the polymeric system can be used to improve the theranostic properties for dual 19F MRI tracer and treatment.

Nanotechnology for Cancer Therapy

Author : Mansoor M. Amiji
Publisher : CRC Press
ISBN 13 : 1420006630
Total Pages : 840 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Nanotechnology for Cancer Therapy by : Mansoor M. Amiji

Download or read book Nanotechnology for Cancer Therapy written by Mansoor M. Amiji and published by CRC Press. This book was released on 2006-12-19 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: While simultaneous breakthroughs occurring in molecular biology and nanoscience/technology will ultimately revolutionize all of medicine, it is with our efforts to prevent, diagnose, and treat cancer that many of the most dramatic advances will occur. In support of this potential, the U.S. National Cancer Institute (NCI) established the Alliance fo

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128173319
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics by : Prashant Kesharwani

Download or read book Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-06-25 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Nano-Oncologicals

Author : Maria José Alonso
Publisher : Springer
ISBN 13 : 3319080849
Total Pages : 478 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Nano-Oncologicals by : Maria José Alonso

Download or read book Nano-Oncologicals written by Maria José Alonso and published by Springer. This book was released on 2014-10-15 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume focuses on emerging technologies in cancer nano medicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nano theranostics and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nano carriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.

Nanopharmaceuticals: Principles and Applications Vol. 3

Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 3 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Nanoengineering of Biomaterials

Author : Sougata Jana
Publisher : John Wiley & Sons
ISBN 13 : 3527349049
Total Pages : 1063 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanoengineering of Biomaterials by : Sougata Jana

Download or read book Nanoengineering of Biomaterials written by Sougata Jana and published by John Wiley & Sons. This book was released on 2022-04-18 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.

Cancer Nanotechnology

Author : Ângela Maria Almeida de Sousa
Publisher : Springer Nature
ISBN 13 : 3031178319
Total Pages : 386 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Cancer Nanotechnology by : Ângela Maria Almeida de Sousa

Download or read book Cancer Nanotechnology written by Ângela Maria Almeida de Sousa and published by Springer Nature. This book was released on 2022-12-13 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer nanotechnology is a growing, emerging area of cross-disciplinary research that aims to develop efficient, specific and noninvasive approaches to restore the health and well-being of all cancer patients through more effective diagnosis and treatment. This new volume serves as a fundamental guide to cutting-edge topics in cancer nanotechnology, including advances in therapy, the use of nanoparticles and nanomaterials, future directions for nanocarriers in cancer therapy, and the application of DNA and RNA nanovaccines. Organized into four sections, the volume presents an overview of research and innovation in the emerging field of nanotechnology as a powerful tool in the diagnosis, imaging and treatment of cancer. International experts author chapters addressing targets of cancer therapy, materials for cancer nanotechnology, strategies for cancer therapy using nanotechnology, and innovative nanotechnologies for cancer diagnosis and treatment. The volume will be useful for a broad audience, including cross-disciplinary researchers, trainees, health professionals, and experts in industry.

Polymeric Nanoparticles for Therapeutic Drug Delivery und Tumor Treatment

Author : Thomas Renette
Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (759 download)

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Book Synopsis Polymeric Nanoparticles for Therapeutic Drug Delivery und Tumor Treatment by : Thomas Renette

Download or read book Polymeric Nanoparticles for Therapeutic Drug Delivery und Tumor Treatment written by Thomas Renette and published by . This book was released on 2011 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymers and Nanomaterials for Gene Therapy

Author : Ravin Narain
Publisher : Woodhead Publishing
ISBN 13 : 0081005210
Total Pages : 303 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Polymers and Nanomaterials for Gene Therapy by : Ravin Narain

Download or read book Polymers and Nanomaterials for Gene Therapy written by Ravin Narain and published by Woodhead Publishing. This book was released on 2016-01-09 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications

Nanoparticle Drug Delivery Systems for Cancer Treatment

Author : Hala Gali-Muhtasib
Publisher : CRC Press
ISBN 13 : 1000681416
Total Pages : 179 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanoparticle Drug Delivery Systems for Cancer Treatment by : Hala Gali-Muhtasib

Download or read book Nanoparticle Drug Delivery Systems for Cancer Treatment written by Hala Gali-Muhtasib and published by CRC Press. This book was released on 2020-02-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Polymeric Nanoparticles and Microspheres

Author : P. Guiot
Publisher : CRC Press
ISBN 13 : 1351092790
Total Pages : 306 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Polymeric Nanoparticles and Microspheres by : P. Guiot

Download or read book Polymeric Nanoparticles and Microspheres written by P. Guiot and published by CRC Press. This book was released on 2018-01-18 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors were asked to emphasize their own experience with nanoparticles or microspheres. They were also encouraged to provide aspects normally not stipulated in specialized reviews. The objective was to produce a book which although written by specialists, presented a subject which could be easily understood by people in different fields of life sciences. Another goal was to set up a condensed work covering many aspects of nanoparticles and microspheres. That is the reason why, although mainly dealing with synthetic drug carriers, the first chapter is related to preparation and physicochemical properties of nanoparticles constructed from natural polymers. This is followed by two chapters involving the application of polymeric drug carriers in cancer therapy. The second chapter extensively describes in vitro and in vivo behaviour of purely synthetic nanoparticles. As ub the case of liposomes, a problem can be that some particles are preferentially taken up by the reticuloendothelial system. Magnetic drug carriers provide a partial answer to this problem since their tropism can be managed by an external magnet. The third chapter is entirely devoted to this aspect. A brief but original application of nanoparticles is given in the fourth chapter by reviewing their use in ocular therapy. Finally, two general applications of polymeric microspheres are discussed in chapters 5 and 6.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128163674
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by : Prashant Kesharwani

Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-01-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Emerging Roles of Nanocarrier in Cancer Therapy

Author : Rishabha Malviya
Publisher : CRC Press
ISBN 13 : 1040105998
Total Pages : 273 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Emerging Roles of Nanocarrier in Cancer Therapy by : Rishabha Malviya

Download or read book Emerging Roles of Nanocarrier in Cancer Therapy written by Rishabha Malviya and published by CRC Press. This book was released on 2024-09-05 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the limitations of existing therapeutic approaches using nanoparticles. Emerging Roles of Nanocarriers in Cancer Therapy will further provide information for the development of successful cancer nanomedicine therapies. Features Explains different types of nanoparticles, targeting mechanisms, and approved nanotherapeutics for oncological implications in cancer treatment. Covers in detail the characteristics of various nanotechnology-based drug delivery systems. Discusses passive and active cellular targeting, ligand-based targeting of nanoparticles, and strategies to improve nanoparticle-cellular membrane interaction. Presents the application of nanotherapeutics, current challenges, and prospects, and describes the path of future research. Highlights smart strategies for improving the clinical impact of cancer nanomedicine. The text is primarily written for graduate students, and academic researchers in the fields of biotechnology, nanotechnology, drug delivery, pharmaceutical science, and pharmacology.

Polymeric Nanomedicines

Author : Marcel Popa
Publisher : Bentham Science Publishers
ISBN 13 : 1608054845
Total Pages : 821 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Polymeric Nanomedicines by : Marcel Popa

Download or read book Polymeric Nanomedicines written by Marcel Popa and published by Bentham Science Publishers. This book was released on 2013-05-29 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades, numerous nanoparticle platforms have been studied for their use in therapeutic applications. This book deals with the description of the construction of technical systems that combines different functionalities which bring liposomes, polymer-drug conjugates, polymer-protein conjugates, dendrimers, polymeric micelles, polymerosomes and other nanoparticles into the realm of nanotechnology proper, as opposed to traditional pharmacology or supramolecular chemistry. The volume additionally covers topics such as passive and active targeting, the strategies used for drug targeting, and the synthesis and characterization of polymeric nanoparticle platforms. Targeted polymeric nanomedicines have shown exciting results in preclinical studies, demonstrating their potential as therapeutic carriers. Therefore, the development of polymeric nanomedicines as therapeutic agents has generated great enthusiasm both in academia and industry. The book is systematically divided into chapters devoted to a class of polymeric nanomedicines. Each chapter also describes relevant aspects relating to drug design and targeting of polymeric nanomedicines wherever possible. In addition, a series of chapters concerning the contribution of polymeric nanomedicines in the treatment of several categories of diseases including cancer, inflammatory, renal, immunological diseases, and brain disorders is also presented. Key features of this book include: - A comprehensive and cutting-edge overview of polymeric nanomedicines available in a single dedicated volume - Discussions on advances in drug delivery systems for a variety of diseases - more than 2000 references, tables, equations, and drawings Readers, whether beginners or experts, will find in this book, contemporary and relevant information regarding the synthesis, evaluation and applications of polymeric nanomedicines. Supplemented with extensive bibliographic references, tables and figures, this book is an essential and incomparable reference for medicinal chemists, biologists, and medical (oncologic) researchers, as well as for scientists, undergraduate and graduate students in the field of medical bioengineering and polymer nanoscience.

Handbook of Polymer and Ceramic Nanotechnology

Author : Chaudhery Mustansar Hussain
Publisher : Springer
ISBN 13 : 9783030405120
Total Pages : 1667 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Handbook of Polymer and Ceramic Nanotechnology by : Chaudhery Mustansar Hussain

Download or read book Handbook of Polymer and Ceramic Nanotechnology written by Chaudhery Mustansar Hussain and published by Springer. This book was released on 2021-09-13 with total page 1667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook examines the recent advances in the nanotechnology of polymers and ceramics, which possess outstanding mechanical properties and compatibility given their unique physical and chemical properties caused by the unusually large surface area to volume ratios and high interfacial reactivity. This handbook highlights the various compositions and morphologies of polymer and ceramic nanomaterials that can serve as powerful tools for the diverse applications in areas such as electronics, photonics, shape-memory alloys, biomaterials and biomedical nanomaterials, graphene-based technologies, and textiles and packaging. The handbook addresses safety, economics, green production and sustainability. The book contains a section on functionalization of these molecules, which only increases the possibility of developing even more versatile materials that can be fine-tuned for specific applications. Filling a gap in the literature, this handbook provides comprehensive coverage of properties, fabrication, characterization, functionalization methods and applications at both experimental and theoretical models scales. Economic, toxicological, regulatory, and environmental concerns regarding applications are also discussed in detail. Special attention is paid to sustainable approaches that reduce costs in terms of chemicals and time consumption. The book covers research trends, challenges, and prospective topics as well.

Single-Chain Polymer Nanoparticles

Author : José A. Pomposo
Publisher : John Wiley & Sons
ISBN 13 : 3527342427
Total Pages : 416 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Single-Chain Polymer Nanoparticles by : José A. Pomposo

Download or read book Single-Chain Polymer Nanoparticles written by José A. Pomposo and published by John Wiley & Sons. This book was released on 2017-12-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists.