Platelet Proteomics

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Publisher : John Wiley & Sons
ISBN 13 : 0470463376
Total Pages : 432 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Platelet Proteomics by : Ángel García-Alonso

Download or read book Platelet Proteomics written by Ángel García-Alonso and published by John Wiley & Sons. This book was released on 2011-05-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separation methods (MudPit), analysis of the general platelet proteome and signaling cascades by gel-based separation methods (2-DE), sub-proteome analyses (secretome/releasate, membrane proteins, organelles). Finally, the last section links the platelet transcriptome and application to disease. This section is highly relevant and includes chapters on proteomics, transcriptomics, functional genomics, systems biology, and their applications to platelet-related diseases.

Platelet Proteomics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118002075
Total Pages : 432 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Platelet Proteomics by : Ángel García-Alonso

Download or read book Platelet Proteomics written by Ángel García-Alonso and published by John Wiley & Sons. This book was released on 2011-04-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separation methods (MudPit), analysis of the general platelet proteome and signaling cascades by gel-based separation methods (2-DE), sub-proteome analyses (secretome/releasate, membrane proteins, organelles). Finally, the last section links the platelet transcriptome and application to disease. This section is highly relevant and includes chapters on proteomics, transcriptomics, functional genomics, systems biology, and their applications to platelet-related diseases.

Platelets

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Publisher : Academic Press
ISBN 13 : 0128134690
Total Pages : 1268 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Platelets by : Alan D. Michelson

Download or read book Platelets written by Alan D. Michelson and published by Academic Press. This book was released on 2019-03-07 with total page 1268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource. Comprehensive and definitive source of state-of-the-art knowledge about platelets Integrates the entire field of platelet biology, pathophysiology, and clinical medicine Written for clinicians, pathologists and scientists by 142 world-renowned experts from 18 countries Completely revised and updated, with 11 new chapters on topics such as platelet glycobiology, the platelet transcriptome, platelet inhibitory receptors, platelet function testing in clinical research trials, therapeutic platelet-rich plasma in wound healing, and new antiplatelet drugs Full color textbook with over 250 illustrations and 15,000 references

Platelets

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Publisher : Elsevier
ISBN 13 : 0080465862
Total Pages : 1386 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Platelets by : Alan D. Michelson

Download or read book Platelets written by Alan D. Michelson and published by Elsevier. This book was released on 2011-08-29 with total page 1386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. First edition won Best Book in Medical Science Award from the Association of American Publishers Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references

Platelet Function

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Publisher : Springer Science & Business Media
ISBN 13 : 1592599176
Total Pages : 400 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Platelet Function by : Martin Quinn

Download or read book Platelet Function written by Martin Quinn and published by Springer Science & Business Media. This book was released on 2007-11-13 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge review of the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed.

Disorders of the Platelets, An Issue of Hematology/Oncology Clinics of North America

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455771899
Total Pages : 366 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Disorders of the Platelets, An Issue of Hematology/Oncology Clinics of North America by : Koneti Rao

Download or read book Disorders of the Platelets, An Issue of Hematology/Oncology Clinics of North America written by Koneti Rao and published by Elsevier Health Sciences. This book was released on 2013-06-28 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics is guest edited by Dr. A. Koneti Rao and focuses on Disorder of the Platelets. Article titles include: Mechanisms of Platelet Activation and Inhibition, Testing Platelet Function,Clinical Implications of Platelet Genomics and Proteomics, Congenital Thrombocytopenias, Immune Thrombocytopenias, Heparin Induced Thrombocytopenia, and Functional defects: Chronic granulomatous disease (CGD) and beyond.

Platelets in Cardiovascular Disease

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Author :
Publisher : Imperial College Press
ISBN 13 : 186094826X
Total Pages : 235 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Platelets in Cardiovascular Disease by : Deepak L. Bhatt

Download or read book Platelets in Cardiovascular Disease written by Deepak L. Bhatt and published by Imperial College Press. This book was released on 2008 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine.Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease.Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.

Platelets in Thrombotic and Non-Thrombotic Disorders

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Author :
Publisher : Springer
ISBN 13 : 3319474626
Total Pages : 1402 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Platelets in Thrombotic and Non-Thrombotic Disorders by : Paolo Gresele

Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Serum/Plasma Proteomics

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Publisher : Springer Nature
ISBN 13 : 1071629786
Total Pages : 591 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Serum/Plasma Proteomics by : David W. Greening

Download or read book Serum/Plasma Proteomics written by David W. Greening and published by Springer Nature. This book was released on 2023-02-13 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third volume provides comprehensive protocols on pre-analytical, analytical, plasma, and serum proteomics. New and updated chapters are divided into nine sections, detailing blood processing and handling strategies, discovery- and targeted-based mass spectrometry, including workflows to aid in discovery and targeted data analysis, in addition to software and bioinformatics for the plasma proteome. This edition further integrates emerging areas in the development of technologies for plasma proteomics and assay platforms in biomarker discovery and translational proteomics, enrichment and detection strategies to understand the plasma proteome, and peptide, lipid and metabolite targeted assays. We also detail the emerging analysis of extracellular vesicles isolated from plasma. Written in the format of the highly successful Methods in Molecular Biology series, each of the 33 chapters includes an introduction to the topic, lists necessary materials and methods, includes hints and tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Serum/Plasma Proteomics: Methods and Protocols, Third Edition aims to be comprehensive guide for researchers.

Platelet Proteomics for Novel Biomarkersof Heart Failure with Preserved Ejection Fraction

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Publisher :
ISBN 13 :
Total Pages : 34 pages
Book Rating : 4.:/5 (951 download)

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Book Synopsis Platelet Proteomics for Novel Biomarkersof Heart Failure with Preserved Ejection Fraction by : Roseanne Raphael

Download or read book Platelet Proteomics for Novel Biomarkersof Heart Failure with Preserved Ejection Fraction written by Roseanne Raphael and published by . This book was released on 2015 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exploring the Human Plasma Proteome

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Publisher : John Wiley & Sons
ISBN 13 : 3527609423
Total Pages : 394 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Exploring the Human Plasma Proteome by : Gilbert S. Omenn

Download or read book Exploring the Human Plasma Proteome written by Gilbert S. Omenn and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the cutting edge of medical diagnostics, plasma proteomics promises to generate a new wave of technologies to help identify many different diseases and disease risks. Plasma and serum are the preferred non-invasive specimens to test normal individuals, at-risk groups, and patients for protein biomarkers discovered and validated to reflect physiological, pathological, and pharmacological phenotypes. These specimens present enormous challenges due to extreme complexity, huge dynamic range in protein concentrations, non-standardized methods of sample processing, and intra- and inter-individual variation from genetics, diet, smoking, hormones, and other sources. This book presents the major findings from the collaborative Plasma Proteome Project organized by the international Human Proteome Organization (HUPO). The chapters are drawn from a larger set of publications in the journal PROTEOMICS. This book provides a valuable foundation for development and applications of proteomics.

A Proteomic Investigation Into the Proteins Released from Platelets

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Author :
Publisher :
ISBN 13 :
Total Pages : 271 pages
Book Rating : 4.:/5 (939 download)

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Book Synopsis A Proteomic Investigation Into the Proteins Released from Platelets by : Róisín O'Connor

Download or read book A Proteomic Investigation Into the Proteins Released from Platelets written by Róisín O'Connor and published by . This book was released on 2008 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Application of Proteomics to the Study of Protein Translation in Stored Platelet Units

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (68 download)

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Book Synopsis Application of Proteomics to the Study of Protein Translation in Stored Platelet Units by :

Download or read book Application of Proteomics to the Study of Protein Translation in Stored Platelet Units written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiovascular Proteomics

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Publisher : Springer Science & Business Media
ISBN 13 : 1597452149
Total Pages : 412 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Cardiovascular Proteomics by : Fernando Vivanco

Download or read book Cardiovascular Proteomics written by Fernando Vivanco and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.

Proteomics: Biomedical and Pharmaceutical Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 1402023227
Total Pages : 396 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Proteomics: Biomedical and Pharmaceutical Applications by : Hubert Hondermarck

Download or read book Proteomics: Biomedical and Pharmaceutical Applications written by Hubert Hondermarck and published by Springer Science & Business Media. This book was released on 2004-08-10 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics. Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered. This volume will be of particular interest to students and professionals engaged in the fields of medicine, biomedical and biopharmaceutical sciences.

Disorders of the Platelets, an Issue of Hematology/Oncology Clinics of North America

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Author :
Publisher : Clinics: Internal Medicine
ISBN 13 : 9781455771028
Total Pages : 0 pages
Book Rating : 4.7/5 (71 download)

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Book Synopsis Disorders of the Platelets, an Issue of Hematology/Oncology Clinics of North America by : A. Koneti Rao

Download or read book Disorders of the Platelets, an Issue of Hematology/Oncology Clinics of North America written by A. Koneti Rao and published by Clinics: Internal Medicine. This book was released on 2013-06-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics is guest edited by Dr. A. Koneti Rao and focuses on Disorder of the Platelets. Article titles include: Mechanisms of Platelet Activation and Inhibition, Testing Platelet Function, Clinical Implications of Platelet Genomics and Proteomics, Congenital Thrombocytopenias, Immune Thrombocytopenias, Heparin Induced Thrombocytopenia, and Functional defects: Chronic granulomatous disease (CGD) and beyond

Development and Application of Proteomic Tools to Study Platelet Function in the Context of Cardiovascular Disease

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Development and Application of Proteomic Tools to Study Platelet Function in the Context of Cardiovascular Disease by : Chengcheng Zhang

Download or read book Development and Application of Proteomic Tools to Study Platelet Function in the Context of Cardiovascular Disease written by Chengcheng Zhang and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: