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Phthalocyanines For Photodynamic Therapy
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Author :Cynthia M. (Cynthia Marie) Allen Publisher :National Library of Canada = Bibliothèque nationale du Canada ISBN 13 :9780612851689 Total Pages :328 pages Book Rating :4.8/5 (516 download)
Book Synopsis Photodynamic Therapy [microform] : Enhancement of Phthalocyanine Targeting from Modifications on the Macrocycle to the Use of Protein Delivery Vehicles by : Cynthia M. (Cynthia Marie) Allen
Download or read book Photodynamic Therapy [microform] : Enhancement of Phthalocyanine Targeting from Modifications on the Macrocycle to the Use of Protein Delivery Vehicles written by Cynthia M. (Cynthia Marie) Allen and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 2001 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemical Aspects of Photodynamic Therapy by : Raymond Bonnett
Download or read book Chemical Aspects of Photodynamic Therapy written by Raymond Bonnett and published by CRC Press. This book was released on 2000-08-07 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photodynamic therapy (PDT) is a ground breaking medical technique which uses lasers to activate light-sensitive chemicals to treat cancer and other diseases without resorting to surgery. For the first time, Chemical Aspects of Photodynamic Therapy introduces in an accessible way the physics, chemistry and biology behind the technique. This highly a
Book Synopsis Synthesis of Phthalocyanines as Photosensitizers for Photodynamic Therapy by : Hongqiao Wu
Download or read book Synthesis of Phthalocyanines as Photosensitizers for Photodynamic Therapy written by Hongqiao Wu and published by . This book was released on 2000 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Silicon Phthalocyanines for Photodynamic Therapy by : Jeffrey C. Berlin
Download or read book Silicon Phthalocyanines for Photodynamic Therapy written by Jeffrey C. Berlin and published by . This book was released on 2006 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phthalocyanines for Photodynamic Therapy by : Yun Liu
Download or read book Phthalocyanines for Photodynamic Therapy written by Yun Liu and published by . This book was released on 2010 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to develop methods for controlling the photostability of phthalocyanines used in photodynamic therapy, the stability of their toluene solutions in presence of radical sources and air under white light was investigated. The results show that phthalocyanines photodecompose in the presence of alkenes or amino groups, and that their photodecomposition is strongly influenced by the nature of the radical source. Based on this study, four sets of silicon phthalocyanines bearing ligands which can act as radical sources or silicon phthalocyanines bearing ligands which can act as reference ligands were synthesized and characterized, and their photostability was studied. One set was composed of three alkoxysilicon phthalocyanines, the second of eight carboxysilicon phthalocyanines, another of a siloxysilicon phthalocyanine and the last of seven carboxylate salts of SiPc[OSi(CH3)2(CH2)3NH(CH3)2]2. The members of the first set are SiPc[O(CH2)4CH3]2, Pc 307, SiPc[OCH2CH=C(CH3)(CH2)2CH=C(CH3)2]2, Pc 302 and SiPc[O(CH2CH=C(CH3)CH2)2CH2CH=C(CH3)2]2, Pc 303; of the second are SiPc[OC(O)(CH2)16CH3]2, Pc 294, SiPc[OC(O)(CH2)7CH=CH(CH2)7CH3]2, Pc 295, SiPc[OC(O)(CH2)6(CH2CH=CH)2(CH2)4CH3]2, Pc 296, SiPc[OC(O)(CH2)6(CH2CH=CH)3CH2CH3]2, Pc 297, SiPc[OC(O)(CH2)2(CH2CH=CH)4(CH2)4CH3]2, Pc 299, SiPc[OC(O)CH2(CH2CH=CH)6CH2CH3]2, Pc 300, SiPc[OC(O)(CH2)3(CH2CH=CH)3(CH2)4CH3]2, Pc 298 and SiPc[OC(O)(CH=C(CH3)CH=CH)2C6H6(CH3)3]2, Pc 301; of the third is SiPc[OSi(CH=CH2)3]2, Pc 279; and of the last are of the type SiPc[OSi(CH3)2(CH2)3NH(CH3)2]22+ [OC(O)R]-2 where the carboxylate anions are stearate, oleate, linoleate, linolenate, arachidonate, retinoate and docosahexaenoate. The results further show that the photodecomposition of phthalocyanines by radicals is strongly influenced by the nature of the radical source. The penetration properties of a Pc 4 - ethanol-propylene glycol formulation, of Pc 4 - Vanicream® formulations with or without Tween® 80, and of Pc 4 salt-Vanicream® formulations with or without Tween® 80 through a model membrane (polydimethylsiloxane) were investigated with a Franz vertical diffusion cell system. An attempt to study the penetration properties of Pc 4 and Pc 4-salt formulations through pig keratomes also was made. Four phthalocyanines designed to release their excited-state energy in a specific direction in space were synthesized and characterized. These were MPc[2,3-O(C2H4CH(CH3)CH2)2C2H4CH(CH3)2]2 where M is H2, Ni, Co or Zn. A better route was developed for the synthesis of the Pc 4 reference compound HOSiPcOSi(CH3)2(CH2)3N(C2H5)2, Pc 34. The Pc 12 naphthalocyanine analogue, SiNc[OSi(CH3)2(CH2)3N(CH3)2]2, was synthesized and characterized.
Book Synopsis Silicon Phthalocyanines for Photodynamic Therapy Studies by :
Download or read book Silicon Phthalocyanines for Photodynamic Therapy Studies written by and published by . This book was released on 2008 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Advances in the Biology, Therapy and Management of Melanoma by : Lester Davids
Download or read book Recent Advances in the Biology, Therapy and Management of Melanoma written by Lester Davids and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.
Author :Wesley M. (Wesley Milton) Sharman Publisher :National Library of Canada = Bibliothèque nationale du Canada ISBN 13 :9780612266155 Total Pages :406 pages Book Rating :4.2/5 (661 download)
Book Synopsis Novel Water-soluble Phthalocyanines for Photodynamic Therapy and Nuclear Imaging [microform] by : Wesley M. (Wesley Milton) Sharman
Download or read book Novel Water-soluble Phthalocyanines for Photodynamic Therapy and Nuclear Imaging [microform] written by Wesley M. (Wesley Milton) Sharman and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1997 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Water Soluble Phthalocyanines for Photodynamic Therapy by : Kieron D. Legge
Download or read book Water Soluble Phthalocyanines for Photodynamic Therapy written by Kieron D. Legge and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phthalocyanines and Some Current Applications by : Yusuf Yilmaz
Download or read book Phthalocyanines and Some Current Applications written by Yusuf Yilmaz and published by BoD – Books on Demand. This book was released on 2017-06-21 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their initial accidental synthesis and characterization in Scotland in the late 1920s, there has been a strong research focus on the use of phthalocyanines (Pcs) as dyes and pigments. In recent years, active research fields have included their use in electrophotography, photovoltaic and solar cells, molecular electronics, Langmuir-Blodgett films, photosensitizers, electrochromic display devices, gas sensors, liquid crystals, low-dimensional conductors, and optical disks. Phthalocyanines possess interesting biological, electronic, optical, catalytic, and structural properties. The main disadvantage is their insolubility in common solvents due to strong intermolecular - interactions. The solubility of phthalocyanines can be increased by various methods such as the formation of anionic and cationic species and both axial and peripheral substitution. Substitution at the nonperipheral and peripheral positions of the benzo moieties usually enhances their solubility in organic solvents. The most important advantage of phthalocyanines compared to porphyrins is that their Q bands lie at longer wavelengths and are considerably more intense. In this book, you will find synthesis and some applications of various phthalocyanine derivatives.
Book Synopsis Synthesis of Phthalocyanines and Naphthalocyanines for Photodynamic Therapy and Photothermal Therapy Studies by : Xinzhan Peng
Download or read book Synthesis of Phthalocyanines and Naphthalocyanines for Photodynamic Therapy and Photothermal Therapy Studies written by Xinzhan Peng and published by . This book was released on 2001 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemical Mechanisms in Photodynamic Therapy with Phthalocyanines by : David R.. Phillips
Download or read book Chemical Mechanisms in Photodynamic Therapy with Phthalocyanines written by David R.. Phillips and published by . This book was released on 1997 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Photodynamic Therapy by : Barbara W. Henderson
Download or read book Photodynamic Therapy written by Barbara W. Henderson and published by CRC Press. This book was released on 2020-07-24 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of photodynamic therapy, 70 expert contributors from the fields of photochemistry, photobiology, photophysics, pharmacology, oncology and surgery, provide multidisciplinary discussions on photodynamic therapy - a rapidly-developing approach to the treatment of solid tumours.;Photodynamic Therapy: Basic Principles and Clinical Applications describes the molecular and cellular effects of photodynamic treatment; elucidates the complex events leading to photodynamics tissue destruction, particularly vascular and inflammatory responses; discusses the principles of light penetration through tissues and optical dosimetry; examines photosensitizer pharmacology and delivery systems; reviews in detail photosensitizer structure-activity relationships; illustrates novel devices that aid light dosimetry and fluorescence detection; and extensively delineates clinical applications, including early diagnosis and treatment.;A comprehensive and up-to-date reference, this book should be useful for oncologists, pharmacologists, surgeons, photobiologists, optical engineers, laser technicians, biologists, physicists, chemists and biochemists involved in cancer research, as well as graduate-level students in these disciplines.
Book Synopsis Synthesis of Novel Unsymmetrical Zinc(II) Phthalocyanines for Photodynamic Therapy by : Lei Duan
Download or read book Synthesis of Novel Unsymmetrical Zinc(II) Phthalocyanines for Photodynamic Therapy written by Lei Duan and published by . This book was released on 2005 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Photosensitizing Compounds by : Gregory R. Bock
Download or read book Photosensitizing Compounds written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders.
Book Synopsis Synthesis of Phthalocyanine Photosensitizers for Photodynamic Therapy Studies by : Ying-Syi Li
Download or read book Synthesis of Phthalocyanine Photosensitizers for Photodynamic Therapy Studies written by Ying-Syi Li and published by . This book was released on 1995 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis and Characterization of Silicon Phthalocyanines for Photodynamic Therapy by : Ming Guo
Download or read book Synthesis and Characterization of Silicon Phthalocyanines for Photodynamic Therapy written by Ming Guo and published by . This book was released on 2008 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: A series of Pc 4 related compounds consisting of OH-substituted derivatives, Pc 4 salts and Pc 4 OH-substituted derivative salts has been prepared. The salts have been synthesized by straightforward acid-base reactions. Solubility studies of the Pc 4, the OH-substituted derivatives, the Pc 4 salts and the OH-substituted derivative salts in representative organic solvents and in aqueous dispersant-containing solutions have been carried out. Different dosage forms of Pc 4 including a liquid salt, aqueous solutions, a mineral oil solution, gels, a cream, and water-swellable films have been formulated. In addition, membrane penetration studies of the formulation of Pc 4 used in a completed Phase I clinical trial done at University Hospitals of Cleveland have been conducted. Polyurethane, cellulose, polyvinylidene fluoride, silicone, pig keratome, and human roof blister membranes have been used in the study. In unrelated work, the known polymers, chrysotile-derived trimethylsiloxy scroll polymer, and chrysotile-derived vinyldimethylsiloxy scroll polymer have been made. Also, the new polymers chrysotile-derived trimethylsiloxy-3-cyanopropylmethylmethoxysiloxy scroll polymer and chrysotile-derived vinyldimethylsiloxy-3-cyanopropylmethylmethoxysiloxy scroll polymer, have been made by a novel pendent group-exchange reaction. Finally, partially platinum-filled scrolls have been prepared.