Photofunctionalization Of Molecular Switch Based On Pyrimidine Ring Rotation In Copper Complexes

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Photofunctionalization of Molecular Switch Based on Pyrimidine Ring Rotation in Copper Complexes

Author : Michihiro Nishikawa
Publisher : Springer Science & Business Media
ISBN 13 : 4431546251
Total Pages : 131 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Photofunctionalization of Molecular Switch Based on Pyrimidine Ring Rotation in Copper Complexes by : Michihiro Nishikawa

Download or read book Photofunctionalization of Molecular Switch Based on Pyrimidine Ring Rotation in Copper Complexes written by Michihiro Nishikawa and published by Springer Science & Business Media. This book was released on 2013-12-16 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed description of photofunctionalization of molecular switch based on pyrimidine ring rotational isomerization in copper complexes bearing two bidentate ligands. The most important features of this work focus on the properties associated with the rotational isomerization based on the two possible coordination geometries at the copper center derived from two nitrogen atoms on the unsymmetrically substituted pyrimidine ring. The functions of systems such as dual emission and redox potential switching based on photo-driven rotation will be of particular interest to readers. Both the functions and the procedures for proving these phenomena are beneficial for the development of more functionalized systems based on material science, molecular science, nanoscience, nanotechnology, electrochemistry, photochemistry, coordination chemistry, physical chemistry, and related disciplines. The finding elucidated here holds promise for handling the photoprocesses of metal complexes, valid for both applications and novel properties. This system is expected make it possible to extract an electrochemical potential response from molecular switches, aiming to simulate the five senses of human beings at a single molecular level.

Immobilized Catalysts

Author : Andreas Kirschning
Publisher : Springer Science & Business Media
ISBN 13 : 9783540209157
Total Pages : 354 pages
Book Rating : 4.2/5 (91 download)

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Book Synopsis Immobilized Catalysts by : Andreas Kirschning

Download or read book Immobilized Catalysts written by Andreas Kirschning and published by Springer Science & Business Media. This book was released on 2004-11-22 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: R. Haag, S. Roller: Polymeric Supports for the Immobilisation of Catalysts .- J. Horn, F. Michalek, C.C. Tzschucke, W. Bannwarth: Non-Covalently Solid-Phase Bound Catalysts for Organic Synthesis .- Y. Uozumi: Recent Progress in Polymeric Palladium Catalysts for Organic Synthesis .- D.E. Bergbreiter, J. Li: Applications of Catalysts on Soluble Supports .- B. Desai, C.O. Kappe: Microwave-Assisted Synthesis Involving Immobilized Catalysts .- A. Kirschning, G. Jas: Applications of Immobilized Catalysts in Continuous Flow Processes .- N. End, K.-U. Schöning: Immobilized Catalysts in Industrial Research and Application .- N. End, K.-U. Schöning: Immobilized Biocatalysts in Industrial Research and Production

Modification of Polymers

Author : Charles E. Carraher
Publisher : Springer Science & Business Media
ISBN 13 : 1461337488
Total Pages : 414 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Modification of Polymers by : Charles E. Carraher

Download or read book Modification of Polymers written by Charles E. Carraher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sheer volume of topics which could have been included under our general title prompted us to make some rather arbitrary decisions about content. Modification by irradiation is not included because the activity in this area is being treated elsewhere. We have chosen to emphasize chemical routes to modification and have striven to pre sent as balanced a representation of current activity as time and page count permit. Industrial applications, both real and potential, are included. Where appropriate, we have encouraged the contributors to include review material to help provide the reader with adequate context. The initial chapter is a review from a historical perspective of polymer modification and contains an extensive bibliography. The remainder of the book is divided into four general areas: Reactions and Preparation of Copolymers Reactions and Preparation of Block and Graft Copolymers Modification Through Condensation Reactions Applications The chemical modification of homopolymers such as polyvinylchlo ride, polyethylene, poly(chloroalkylene sulfides), polysulfones, poly chloromethylstyrene, polyisobutylene, polysodium acrylate, polyvinyl alcohol, polyvinyl chloroformate, sulfonated polystyrene; block and graft copolymers such as poly(styrene-block-ethylene-co-butylene block-styrene), poly(I,4-polybutadiene-block ethylene oxide), star chlorine-telechelic polyisobutylene, poly(isobutylene-co-2,3-dimethyl- 1,3-butadiene), poly(styrene-co-N-butylmethacrylate); cellulose, dex tran and inulin, is described.

Retroviruses and Insights into Cancer

Author : Jaquelin Dudley
Publisher : Springer Science & Business Media
ISBN 13 : 0387095810
Total Pages : 372 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Retroviruses and Insights into Cancer by : Jaquelin Dudley

Download or read book Retroviruses and Insights into Cancer written by Jaquelin Dudley and published by Springer Science & Business Media. This book was released on 2010-10-22 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.

Cell-Extracellular Matrix Interactions in Cancer

Author : Roy Zent
Publisher : Springer Science & Business Media
ISBN 13 : 1441908145
Total Pages : 316 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cell-Extracellular Matrix Interactions in Cancer by : Roy Zent

Download or read book Cell-Extracellular Matrix Interactions in Cancer written by Roy Zent and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.

Studies on Renal Disorders

Author : Toshio Miyata
Publisher : Springer Science & Business Media
ISBN 13 : 1607618575
Total Pages : 781 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Studies on Renal Disorders by : Toshio Miyata

Download or read book Studies on Renal Disorders written by Toshio Miyata and published by Springer Science & Business Media. This book was released on 2010-12-17 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

Epigenetic Aspects of Chronic Diseases

Author : Helmtrud I. Roach
Publisher : Springer Science & Business Media
ISBN 13 : 1848826443
Total Pages : 246 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Epigenetic Aspects of Chronic Diseases by : Helmtrud I. Roach

Download or read book Epigenetic Aspects of Chronic Diseases written by Helmtrud I. Roach and published by Springer Science & Business Media. This book was released on 2011-04-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development. This book provides new insights into treatment, including modulation of epigenetic regulation. Each chapter gives an outline of a respective disease, explains why epigenetics may be involved in the disease process and then presents the evidence of how changes in epigenetic status contribute to initiation and progress of the disease. The final chapters look towards future therapeutic treatment, based on manipulation of epigenetic aspects. Written by widely published experts, Epigenetic Aspects of Chronic Diseases is a valuable reference tool for clinicians and researchers who investigate and treat chronic diseases, as well as health care personnel, post-doctoral fellows and medical or dental students.

New Technologies for Toxicity Testing

Author : Michael Balls
Publisher : Springer Science & Business Media
ISBN 13 : 1461430550
Total Pages : 282 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis New Technologies for Toxicity Testing by : Michael Balls

Download or read book New Technologies for Toxicity Testing written by Michael Balls and published by Springer Science & Business Media. This book was released on 2012-03-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Of course, many of the techniques and methods described in this volume are in the early stages of development, and much work will be needed to ensure their further improvement, optimisation and validation. However, we are confident that this will be achieved and that, just as with the in vitro assays that were validated and granted regulatory acceptance over the last decade, these, and many other new, advanced methods, will likewise become part of the toxicologist’s improved toolbox for coping with increasingly stringent and numerous regulatory requirements and test chemicals, while placing less reliance on traditional testing paradigms.

Bioinformatics for Immunomics

Author : Darren D.R. Flower
Publisher : Springer
ISBN 13 : 1441905405
Total Pages : 201 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bioinformatics for Immunomics by : Darren D.R. Flower

Download or read book Bioinformatics for Immunomics written by Darren D.R. Flower and published by Springer. This book was released on 2009-10-03 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.

Principles of Statistical Genomics

Author : Shizhong Xu
Publisher : Springer Science & Business Media
ISBN 13 : 0387708065
Total Pages : 428 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Principles of Statistical Genomics by : Shizhong Xu

Download or read book Principles of Statistical Genomics written by Shizhong Xu and published by Springer Science & Business Media. This book was released on 2012-09-10 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach. Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data. Resourceful and easy to use, Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics.

Polyploidization and Cancer

Author : Randy Y.C. Poon
Publisher : Springer Science & Business Media
ISBN 13 : 1441961992
Total Pages : 157 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Polyploidization and Cancer by : Randy Y.C. Poon

Download or read book Polyploidization and Cancer written by Randy Y.C. Poon and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.

Crossroads between Innate and Adaptive Immunity III

Author : Bali Pulendran
Publisher : Springer Science & Business Media
ISBN 13 : 1441956328
Total Pages : 179 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Crossroads between Innate and Adaptive Immunity III by : Bali Pulendran

Download or read book Crossroads between Innate and Adaptive Immunity III written by Bali Pulendran and published by Springer Science & Business Media. This book was released on 2011-08-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a collection of reviews derived from work presented at the Aegean Conference: “3rd Crossroads between innate and adaptive immunity” which occurred during September 27 - October 2, 2009 at the Minoa Palace Conference Center in Chania, Crete, Greece. This meeting was the third in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The various facets of the innate response, including dendritic cells, T cells, B cells, NK cells, NK-T cells and the complement cascade during the host response to pathogens and tumors is only now starting to be elucidated. The respective fields that focus on these immune cells and molecules have tended to be relatively compartmentalized, and yet emerging evidence points to the interconnectedness of these facets in coordinating the innate response, and its subsequent impact on the adaptive response. The goal of this conference was to initiate cross-talk between these diverse immunological fields, and promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response and ultimately facilitate collaboration between these areas of study. Following on the footsteps of the outstanding success of its precursors, the “3rd Crossroads between Innate and Adaptive Immunity” Aegean Conference was highly successful in bringing together and connecting scientists and experts from around the world to address critical areas of Innate and Adaptive immunity.

The Genetics and Development of Scoliosis

Author : Kenro Kusumi
Publisher : Springer Science & Business Media
ISBN 13 : 1441914064
Total Pages : 227 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Genetics and Development of Scoliosis by : Kenro Kusumi

Download or read book The Genetics and Development of Scoliosis written by Kenro Kusumi and published by Springer Science & Business Media. This book was released on 2009-12-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.

Advances in Yersinia Research

Author : Alzira Maria Paiva de Almeida
Publisher : Springer Science & Business Media
ISBN 13 : 1461435617
Total Pages : 363 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Advances in Yersinia Research by : Alzira Maria Paiva de Almeida

Download or read book Advances in Yersinia Research written by Alzira Maria Paiva de Almeida and published by Springer Science & Business Media. This book was released on 2012-07-11 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia. The event is held every four years in a different country and for the Yersinia 2010, an interesting and updated program covering advances in research in Yersiniae was organized. The major advances achieved over the past four years since the last symposium held in Lexington, USA in 2006 were divided into eight chapters: Epidemiology, Clinical, Diagnostic and Therapeutic aspects; Ecology and Modeling; Genomic/Transcriptomics and Large Scale Population; Immune Response and Vaccine; Pathogenesis and Pathogenicity Factors; Cellular Yersiniology; Bacterial Structure and Metabolism: Roles in Pathogenesis and Bacterial Life Style. The purpose of the book is to extend cutting edge knowledge on Yersinia discussed during the 10th International Symposium.

Genetics and Genomics of Populus

Author : Stefan Jansson
Publisher : Springer
ISBN 13 : 1441915419
Total Pages : 384 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Genetics and Genomics of Populus by : Stefan Jansson

Download or read book Genetics and Genomics of Populus written by Stefan Jansson and published by Springer. This book was released on 2010-03-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Genomics of Populus provides an indepth description of the genetic and genomic tools and approaches for Populus, examines the biology that has been elucidated using genomics, and looks to the future of this unique model plant. This volume is designed to serve both experienced Populus researchers and newcomers to the field. Contributors to the volume are a blend of researchers, some who have spent most of their research career on Populus and others that have moved to Populus from other model systems. Research on Populus forms a useful complement to research on Arabidopsis. In fact, many plant species found in nature are – in terms of the life history and genetics – more similar to Populus than to Arabidopsis. Thus, the genetic and genomic strategies and tools developed by the Populus community, and showcased in this volume, will hopefully provide inspiration for researchers working in other, less well developed, systems.

Recent Advances on Model Hosts

Author : Eleftherios Mylonakis
Publisher : Springer Science & Business Media
ISBN 13 : 1441956387
Total Pages : 135 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Recent Advances on Model Hosts by : Eleftherios Mylonakis

Download or read book Recent Advances on Model Hosts written by Eleftherios Mylonakis and published by Springer Science & Business Media. This book was released on 2011-12-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most studies of bacterial or fungal infectious diseases focus separately on the pathogenic microbe, the host response, or the characterization of therapeutic compounds. Compartmentalization of pathogenesis-related research into an analysis of the “pathogen”, the “host,” or the “antimicrobial compound” has largely been dictated by the lack of model systems in which all of these approaches can be used simultaneously, as well as by the traditional view that microbiology, immunology, and chemical biology and pharmacology are separate disciplines. An increasing number of workers from different fields have turned to insects, fish, worms and other model hosts as facile, ethically expedient, relatively simple, and inexpensive hosts to model a variety of human infectious diseases and to study host responses and innate immunity. Because many of these hosts are genetically tractable, they can be used in conjunction with an appropriate pathogen to facilitate the discovery of novel features of the host innate immune response. This book provides a series of reports from the 1st International Conference on Model Hosts. This first of its kind meeting focused on invertebrate, vertebrate and amoeboid systems used for the study of host-pathogen interactions, virulence and immunity, as well as on the relevance of these pathogenesis systems and mammalian models. Importantly, a common, fundamental set of molecular mechanisms is employed by a significant number of microbial pathogens against a widely divergent array of metazoan hosts. Moreover, the evolutionarily conserved immune responses of these model hosts have contributed important insights to our understanding of the innate immune response of mammals. This book provides a series of reports from the 1st International Conference on Model Hosts. This first of its kind meeting focused on invertebrate, vertebrate and amoeboid systems used for the study of host-pathogen interactions, virulence and immunity, as well as on the relevance of these pathogenesis systems and mammalian models. Importantly, a common, fundamental set of molecular mechanisms is employed by a significant number of microbial pathogens against a widely divergent array of metazoan hosts. Moreover, the evolutionarily conserved immune responses of these model hosts have contributed important insights to our understanding of the innate immune response of mammals.

Knowledge and Technology Transfer for Plant Pathology

Author : Nigel Hardwick
Publisher : Springer Science & Business Media
ISBN 13 : 9048122163
Total Pages : 132 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Knowledge and Technology Transfer for Plant Pathology by : Nigel Hardwick

Download or read book Knowledge and Technology Transfer for Plant Pathology written by Nigel Hardwick and published by Springer Science & Business Media. This book was released on 2010-11-04 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains fuller versions of the papers and posters presented in the Knowledge and Technology Transfer and Teaching Plant Pathology sessions at the 9th International Congress of Plant Pathology held in Turin, Italy in 2008. Communication is an essential area for plant pathologists and it is not just the publication of results in the scientific press that is important. In a world where there is a major shortage of food and where a significant amount of it is destroyed by pests and diseases before it ever reaches the consumer, it is important to provide support to those who produce the food in order to reduce the losses. Reducing crop losses not only has an impact on health, but also wealth and, therefore, the ability to survive. With an ever-increasing demand on food supplies due to increases in population, and changes in life-style associated with rising incomes in certain parts of the world, plant pathologists have a pivotal role to play in contributing to global food security. Aspects of crop protection have lost favour with the general public because of concerns about environmental pollution and genetic modification of crops. This has had a ‘knock on’ effect in the recruitment and training of crop protectionist in g- eral and a concomitant impact on courses available at universities. However, it has never been more important to train people with good communication skills and an ability to solve problems to tackle the complexities of pathogen and plant interactions.