Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Phenotypic And Genetic Association Between Production full books in PDF, epub, and Kindle. Read online Phenotypic And Genetic Association Between Production ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Faik Atroshi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (17 download)
Download or read book Phenotypic and genetic association between production/reproduction traits written by Faik Atroshi and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Faik Atroshi
Publisher :
ISBN 13 :
Total Pages : 85 pages
Book Rating : 4.:/5 (647 download)
Download or read book Phenotypic and Genetic Association Between Production written by Faik Atroshi and published by . This book was released on 1979 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Faik Atroshi
Publisher :
ISBN 13 :
Total Pages : 85 pages
Book Rating : 4.:/5 (256 download)
Download or read book Phenotypic and Genetic Association Between Production/reproduction Traits and Blood Biochemical Polymorphic Characters in Finnsheep written by Faik Atroshi and published by . This book was released on 1979 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101964
Total Pages : 385 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genes, Behavior, and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-12-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309108675
Total Pages : 429 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biosocial Surveys written by National Research Council and published by National Academies Press. This book was released on 2008-01-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309453291
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)
Download or read book An Evidence Framework for Genetic Testing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.
Author : Richard Dawkins
Publisher : Oxford University Press
ISBN 13 : 0198788916
Total Pages : 486 pages
Book Rating : 4.1/5 (987 download)
Download or read book The Extended Phenotype written by Richard Dawkins and published by Oxford University Press. This book was released on 2016 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Selfish Gene, Richard Dawkins crystallized the gene's eye view of evolution developed by W.D. Hamilton and others. The book provoked widespread and heated debate. Written in part as a response, The Extended Phenotype gave a deeper clarification of the central concept of the gene as the unit of selection; but it did much more besides. In it, Dawkins extended the gene's eye view to argue that the genes that sit within an organism have an influence that reaches out beyond the visible traits in that body - the phenotype - to the wider environment, which can include other individuals. So, for instance, the genes of the beaver drive it to gather twigs to produce the substantial physical structure of a dam; and the genes of the cuckoo chick produce effects that manipulate the behaviour of the host bird, making it nurture the intruder as one of its own. This notion of the extended phenotype has proved to be highly influential in the way we understand evolution and the natural world. It represents a key scientific contribution to evolutionary biology, and it continues to play an important role in research in the life sciences. The Extended Phenotype is a conceptually deep book that forms important reading for biologists and students. But Dawkins' clear exposition is accessible to all who are prepared to put in a little effort. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309165865
Total Pages : 184 pages
Book Rating : 4.3/5 (91 download)
Download or read book Understanding Racial and Ethnic Differences in Health in Late Life written by National Research Council and published by National Academies Press. This book was released on 2004-09-08 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.
Author : Marcelino Pérez de la Vega
Publisher : Springer
ISBN 13 : 3319635263
Total Pages : 304 pages
Book Rating : 4.3/5 (196 download)
Download or read book The Common Bean Genome written by Marcelino Pérez de la Vega and published by Springer. This book was released on 2017-12-20 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides insights into the genetics and the latest advances in genomics research on the common bean, offering a timely overview of topics that are pertinent for future developments in legume genomics. The common bean (Phaseolus vulgaris L.) is the most important grain legume crop for food consumption worldwide, as well as a model for legume research, and the availability of the genome sequence has completely changed the paradigm of the ongoing research on the species. Key topics covered include the numerous genetic and genomic resources, available tools, the identified genes and quantitative trait locus (QTL) identified, and there is a particular emphasis on domestication. It is a valuable resource for students and researchers interested in the genetics and genomics of the common bean and legumes in general.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)
Download or read book STATISTICAL METHOD of GENETIC ASSOCIATION STUDIES written by and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract : In genome-wide association studies (GWAS) for thousands of phenotypes in biobanks, most binary phenotypes have substantially fewer cases than controls. Many widely used approaches for joint analysis of multiple phenotypes in association studies produce inflated type I error rates for such extremely unbalanced case-control phenotypes. In our research, we develop two novel methods to jointly analyze multiple unbalanced case-control phenotypes to circumvent this issue. In the first method, we cluster multiple phenotypes into different clusters based on a hierarchical clustering method, then we merge phenotypes in each cluster into a single phenotype. In each cluster, we use the saddlepoint approximation to estimate the p-value of an association test between the merged phenotype and a SNP which eliminates the issue of inflated type I error rate of the test for extremely unbalanced case-control phenotypes. Finally, we use the Cauchy combination method to obtain an integrated p-value for all clusters to test the association between multiple phenotypes and a SNP. In the second method, we first construct a Multi-Layer Network (MLN) using all individuals with at least one case status among all phenotypes. Then, we introduce a computational efficient community detection method to group phenotypes into different disjoint clusters based on the MLN. The phenotypes in the same cluster are merged to a single phenotype which mainly eliminates the issue of inflated type I error rate of test for extremely unbalanced binary phenotypes. Finally, to test the association between all phenotypes and a SNP, we use the score test statistic to test the association between each merged phenotype and a SNP and then use the Omnibus test to obtain an overall p-value (MLN-O). Extensive simulation studies reveal that the newly proposed approaches can control type I error rates and are more powerful than other methods we compared with. The real data analyses also show that our methods outperform other methods we compared with.
Author : Benzecri
Publisher : CRC Press
ISBN 13 : 058536303X
Total Pages : 684 pages
Book Rating : 4.5/5 (853 download)
Download or read book Correspondence Analysis Handbook written by Benzecri and published by CRC Press. This book was released on 1992-01-22 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference/text presents a complete introduction to the practice of data analysis - clarifying the geometrical language used, explaining the formulae, reviewing linear algebra and multidimensional Euclidean geometry, and including proofs of results. It is intended as either a self-study guide for professionals involved in experimental
Author : Benedikt Hallgrimsson Ph.D.
Publisher : Univ of California Press
ISBN 13 : 0520948823
Total Pages : 469 pages
Book Rating : 4.5/5 (29 download)
Download or read book Epigenetics written by Benedikt Hallgrimsson Ph.D. and published by Univ of California Press. This book was released on 2011-04-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.
Author : Kevin Davies
Publisher : Simon and Schuster
ISBN 13 : 1416569618
Total Pages : 352 pages
Book Rating : 4.4/5 (165 download)
Download or read book The $1,000 Genome written by Kevin Davies and published by Simon and Schuster. This book was released on 2015-08-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence--a comprehensive map of the 3 billion letters in our DNA--is rapidly and inevitably dropping to just $1,000. Dozens of men and women--scientists, entrepreneurs, celebrities, and patients--have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer's or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions--and many more--by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure.
Author : J. Craig Venter
Publisher : Penguin
ISBN 13 : 1101202564
Total Pages : 400 pages
Book Rating : 4.1/5 (12 download)
Download or read book A Life Decoded written by J. Craig Venter and published by Penguin. This book was released on 2007-10-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309171474
Total Pages : 167 pages
Book Rating : 4.3/5 (91 download)
Download or read book Microbial Status and Genetic Evaluation of Mice and Rats written by National Research Council and published by National Academies Press. This book was released on 2000-10-30 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: US/Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US/Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes. In addition to these publications, the meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats. In cooperation with the Comparative Medicine section of NCRR/NIH, the ILAR Council and staff are pleased to become the host for this important annual meeting and look forward to participating in future meetings. The support and sponsorship of NCRR (P40 RR 11611) in the United States and the Central Institute for Experimental Animals in Japan are gratefully acknowledged. Bringing together the leading scientists in the field of laboratory animal care has resulted in increased understanding of American and Japanese approaches to laboratory animal science and should continue to strengthen efforts to harmonize approaches aimed at resolving common challenges in the use of animal models for biomedical research and testing. This effort to improve understanding and cooperation between Japan and the United States should also be useful in developing similar interaction with other regions of the world including Europe, Australia, and Southeast Asia.
Author : David W. Pfennig
Publisher : CRC Press
ISBN 13 : 1000387585
Total Pages : 479 pages
Book Rating : 4.0/5 (3 download)
Download or read book Phenotypic Plasticity & Evolution written by David W. Pfennig and published by CRC Press. This book was released on 2021-05-31 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phenotypic plasticity – the ability of an individual organism to alter its features in direct response to a change in its environment – is ubiquitous. Understanding how and why this phenomenon exists is crucial because it unites all levels of biological inquiry. This book brings together researchers who approach plasticity from diverse perspectives to explore new ideas and recent findings about the causes and consequences of plasticity. Contributors also discuss such controversial topics as how plasticity shapes ecological and evolutionary processes; whether specific plastic responses can be passed to offspring; and whether plasticity has left an important imprint on the history of life. Importantly, each chapter highlights key questions for future research. Drawing on numerous studies of plasticity in natural populations of plants and animals, this book aims to foster greater appreciation for this important, but frequently misunderstood phenomenon. Key Features Written in an accessible style with numerous illustrations, including many in color Reviews the history of the study of plasticity, including Darwin’s views Most chapters conclude with recommendations for future research
