Phenotypes and Genotypes

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Author :
Publisher : Springer
ISBN 13 : 1447153103
Total Pages : 232 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Phenotypes and Genotypes by : Florian Frommlet

Download or read book Phenotypes and Genotypes written by Florian Frommlet and published by Springer. This book was released on 2016-02-12 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

The Extended Phenotype

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Publisher : Oxford University Press
ISBN 13 : 0198788916
Total Pages : 486 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The Extended Phenotype by : Richard Dawkins

Download or read book The Extended Phenotype written by Richard Dawkins and published by Oxford University Press. This book was released on 2016 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Selfish Gene, Richard Dawkins crystallized the gene's eye view of evolution developed by W.D. Hamilton and others. The book provoked widespread and heated debate. Written in part as a response, The Extended Phenotype gave a deeper clarification of the central concept of the gene as the unit of selection; but it did much more besides. In it, Dawkins extended the gene's eye view to argue that the genes that sit within an organism have an influence that reaches out beyond the visible traits in that body - the phenotype - to the wider environment, which can include other individuals. So, for instance, the genes of the beaver drive it to gather twigs to produce the substantial physical structure of a dam; and the genes of the cuckoo chick produce effects that manipulate the behaviour of the host bird, making it nurture the intruder as one of its own. This notion of the extended phenotype has proved to be highly influential in the way we understand evolution and the natural world. It represents a key scientific contribution to evolutionary biology, and it continues to play an important role in research in the life sciences. The Extended Phenotype is a conceptually deep book that forms important reading for biologists and students. But Dawkins' clear exposition is accessible to all who are prepared to put in a little effort. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

Skin in the Game

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Author :
Publisher :
ISBN 13 : 9781913505189
Total Pages : pages
Book Rating : 4.5/5 (51 download)

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Book Synopsis Skin in the Game by : Paulo Scott

Download or read book Skin in the Game written by Paulo Scott and published by . This book was released on 2022-01-04 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Revolutionary Phenotype: The amazing story of how life begins and how it ends

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Author :
Publisher : Lulu.com
ISBN 13 : 0359570798
Total Pages : 142 pages
Book Rating : 4.3/5 (595 download)

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Book Synopsis The Revolutionary Phenotype: The amazing story of how life begins and how it ends by : J. -F. Gariépy

Download or read book The Revolutionary Phenotype: The amazing story of how life begins and how it ends written by J. -F. Gariépy and published by Lulu.com. This book was released on 2019-04-10 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Revolutionary Phenotype is a science book that brings us four billion years into the past, when the first living molecules showed up on Planet Earth. Unlike what was previously thought, we learn that DNA-based life did not emerge from random events in a primordial soup. Indeed, the first molecules of DNA were fabricated by a previous life form. By describing the fascinating events referred to as Phenotypic Revolutions, this book provides a dire warning to humanity: if humans continue to play with their own genes, we will be the next life form to fall to our own creation.

An Evidence Framework for Genetic Testing

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Publisher : National Academies Press
ISBN 13 : 0309453291
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis An Evidence Framework for Genetic Testing by : National Academies of Sciences, Engineering, and Medicine

Download or read book An Evidence Framework for Genetic Testing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.

The Germ-plasm

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Author :
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Germ-plasm by : August Weismann

Download or read book The Germ-plasm written by August Weismann and published by . This book was released on 1893 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Flexible Phenotype

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Publisher : Oxford University Press
ISBN 13 : 0199233721
Total Pages : 249 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis The Flexible Phenotype by : Theunis Piersma

Download or read book The Flexible Phenotype written by Theunis Piersma and published by Oxford University Press. This book was released on 2011 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In essence, the authors argue for the existence of direct, measurable, links between phenotype and ecology.

Epigenetics

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Publisher : Univ of California Press
ISBN 13 : 0520948823
Total Pages : 469 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Epigenetics by : Benedikt Hallgrimsson Ph.D.

Download or read book Epigenetics written by Benedikt Hallgrimsson Ph.D. and published by Univ of California Press. This book was released on 2011-04-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.

Phenotypic Plasticity

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Publisher : JHU Press
ISBN 13 : 9780801867880
Total Pages : 356 pages
Book Rating : 4.8/5 (678 download)

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Book Synopsis Phenotypic Plasticity by : Massimo Pigliucci

Download or read book Phenotypic Plasticity written by Massimo Pigliucci and published by JHU Press. This book was released on 2001-08-17 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The author begins by defining phenotypic plasticity and detailing its history, including important experiments and methods of statistical and graphical analysis. He then provides extended examples and discussion of the molecular basis of plasticity, the plasticity of development, the ecology of plastic responses, and the role of costs and constraints in the evolution of plasticity. A brief epilogue looks at how plasticity studies shed light on the nature/nurture debate in the popular media.".

From Genotype to Phenotype

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780124662575
Total Pages : 320 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis From Genotype to Phenotype by : Sue Malcolm

Download or read book From Genotype to Phenotype written by Sue Malcolm and published by Gulf Professional Publishing. This book was released on 2001-11-19 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the Human Molecular Genetics series covers such genotype-phenotype correlations as clinical and environmental aspects, gene structure, expression, and mutation. Also discussed are models of certain diseases and future prospects for treatment and prevention. This book provides the reader with a basic overview of the physical expression of genetic disease before discussing in detail the most recent research and therapeutic developments.

Rise and Fall of Epithelial Phenotype

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Publisher : Springer Science & Business Media
ISBN 13 : 0387286713
Total Pages : 341 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Rise and Fall of Epithelial Phenotype by : Pierre Savagner

Download or read book Rise and Fall of Epithelial Phenotype written by Pierre Savagner and published by Springer Science & Business Media. This book was released on 2007-07-05 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.

Gene Expression and Phenotypic Traits

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Publisher : BoD – Books on Demand
ISBN 13 : 183880031X
Total Pages : 212 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Gene Expression and Phenotypic Traits by : Yuan-Chuan Chen

Download or read book Gene Expression and Phenotypic Traits written by Yuan-Chuan Chen and published by BoD – Books on Demand. This book was released on 2020-04-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene expression is the most fundamental level at which genotype gives rise to phenotype, which is an obvious, observable, and measurable trait. Phenotype is dependent on genetic makeup of the organism and influenced by environmental conditions. This book explores the significance, mechanism, function, characteristic, determination, and application of gene expression and phenotypic traits.

Molecular Photofitting

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Publisher : Elsevier
ISBN 13 : 0080551378
Total Pages : 711 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Molecular Photofitting by : Tony Frudakis Ph.D.

Download or read book Molecular Photofitting written by Tony Frudakis Ph.D. and published by Elsevier. This book was released on 2010-07-19 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects. Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system. - Explains how physical descriptions of individuals can be generated using only their DNA - Contains case studies that show how this new forensic technology is used in practical application - Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts

Abnormal Skeletal Phenotypes

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Publisher : Springer Science & Business Media
ISBN 13 : 3540303618
Total Pages : 970 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Abnormal Skeletal Phenotypes by : Alessandro Castriota-Scanderbeg

Download or read book Abnormal Skeletal Phenotypes written by Alessandro Castriota-Scanderbeg and published by Springer Science & Business Media. This book was released on 2006-03-20 with total page 970 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking a symptom-oriented approach, this book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. Its clear structure makes it an essential, practical guide for radiologists, geneticists, and pediatricians.

Environmental Genomics

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Publisher : Springer Science & Business Media
ISBN 13 : 1588297772
Total Pages : 363 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Environmental Genomics by : C. Cristofre Martin

Download or read book Environmental Genomics written by C. Cristofre Martin and published by Springer Science & Business Media. This book was released on 2008-01-18 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a manual for an environmental scientist who wishes to embrace genomics to answer environmental questions. The volume covers: gene expression profiling, whole genome and chromosome mutation detection, and methods to assay genome diversity and polymorphisms within a particular environment. This book provides a systematic framework for determining environmental impact and ensuring human health and the sustainability of natural populations.

Spine Phenotypes

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Publisher : Academic Press
ISBN 13 : 0128227796
Total Pages : 418 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Spine Phenotypes by : Dino Samartzis

Download or read book Spine Phenotypes written by Dino Samartzis and published by Academic Press. This book was released on 2022-07-08 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry. - Book chapters devoted to specific imaging phenotypes with discussion of their clinical correlates - Imaging phenotypes provided with examples of established phenotypic measurements and a range of normal and pathologic images - Multiauthor, multidisciplinary contributions comprising world leaders in the field of spine imaging, research, and clinical practice

Principles of Biology

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Publisher :
ISBN 13 : 9781636350417
Total Pages : pages
Book Rating : 4.3/5 (54 download)

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Book Synopsis Principles of Biology by : Lisa Bartee

Download or read book Principles of Biology written by Lisa Bartee and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.