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Phase Iii Interim Report
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Book Synopsis Low Altitude Atmospheric Turbulence LO-LOCAT Phase III Interim Report by : K. R. Monson
Download or read book Low Altitude Atmospheric Turbulence LO-LOCAT Phase III Interim Report written by K. R. Monson and published by . This book was released on 1969 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this report describe accomplishments during the first half of the Low-Level Critical Air Turbulence (LO-LOCAT) Phase III program. Data that were obtained during flight over routes near McConnell Air Force Base, Kansas, and Edwards Air Force Base, California, are presented. Also included are time histories of some of the larger magnitude gust velocities recorded over the Peterson Field, Colorado route. Approximately 72 hours of low-level (0-1000 feet) turbulence and associated meteorological data recorded from August 16, 1968, through January 8, 1969, are presented. The turbulence environment is analyzed in terms of gust velocity primary peaks, amplitude samples, rms values, maximum values and derived equivalent gusts. Mathematical expressions for turbulence spectra and scale length statistics, and correlations between atmospheric gust velocities and meteorological and geophysical phenomena are shown. The most predominant characteristics of these data are the increases in rms values, scale lengths, Taylor micro scales and maximum gust values as compared to the LO-LOCAT Phases I and II data. These differences are attributed to the increased speed of the Phase III airplane which is providing a better definition of the longer wavelengths of atmospheric turbulence. This report consists of two volumes. Volume I contains a discussion of data acquisition and quality, along with a preliminary analysis of turbulence and meteorological data.
Book Synopsis Phase 3 Interim Report Summary by : Ontario Waste Management Corporation
Download or read book Phase 3 Interim Report Summary written by Ontario Waste Management Corporation and published by . This book was released on 1983 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Data Monitoring Committees in Clinical Trials by : Susan S. Ellenberg
Download or read book Data Monitoring Committees in Clinical Trials written by Susan S. Ellenberg and published by John Wiley & Sons. This book was released on 2003-01-17 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been substantial growth in the use of data monitoring committees in recent years, by both government agencies and the pharmaceutical industry. This growth has been brought about by increasing recognition of the value of such committees in safeguarding trial participants as well as protecting trial integrity and the validity of conclusions. This very timely book describes the operation of data monitoring committees, and provides an authoritative guide to their establishment, purpose and responsibilities. * Provides a practical overview of data monitoring in clinical trials. * Describes the purpose, responsibilities and operation of data monitoring committees. * Provides directly applicable advice for those managing and conducting clinical trials, and those serving on data monitoring committees. * Gives insight into clinical data monitoring to those sitting on regulatory and ethical committees. * Discusses issues pertinent to those working in clinical trials in both the US and Europe. The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators, and those working in regulatory affairs and bioethics.
Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council
Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Book Synopsis Interim Report: Phase III - Corrections ... by : Virginia. State Crime Commission. Study Unit on Corrections
Download or read book Interim Report: Phase III - Corrections ... written by Virginia. State Crime Commission. Study Unit on Corrections and published by . This book was released on 1974 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sharing Clinical Trial Data by : Institute of Medicine
Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Book Synopsis Report by : United States. Office of Coal Research
Download or read book Report written by United States. Office of Coal Research and published by . This book was released on 1973 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Annual Report by : United States. Office of Coal Research
Download or read book Annual Report written by United States. Office of Coal Research and published by . This book was released on 1970 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 208 Data Clearinghouse written by and published by . This book was released on 1980 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis FCC Record by : United States. Federal Communications Commission
Download or read book FCC Record written by United States. Federal Communications Commission and published by . This book was released on 2005 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Public Roads written by and published by . This book was released on 1967 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NASA SP-7500 by : United States. National Aeronautics and Space Administration
Download or read book NASA SP-7500 written by United States. National Aeronautics and Space Administration and published by . This book was released on 1968 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fossil Energy Update written by and published by . This book was released on 1978 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. National Highway Traffic Safety Administration. Office of Administrative Services Publisher : ISBN 13 : Total Pages :360 pages Book Rating :4.3/5 (91 download)
Book Synopsis Technical Reports of the National Highway Traffic Safety Administration by : United States. National Highway Traffic Safety Administration. Office of Administrative Services
Download or read book Technical Reports of the National Highway Traffic Safety Administration written by United States. National Highway Traffic Safety Administration. Office of Administrative Services and published by . This book was released on 1973 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Trials by : Stuart J. Pocock
Download or read book Clinical Trials written by Stuart J. Pocock and published by John Wiley & Sons. This book was released on 2013-07-17 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author's personal experience.
Book Synopsis Group Sequential Methods with Applications to Clinical Trials by : Christopher Jennison
Download or read book Group Sequential Methods with Applications to Clinical Trials written by Christopher Jennison and published by CRC Press. This book was released on 1999-09-15 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion. Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Research in group sequential analysis has progressed rapidly over the past 20 years. Group Sequential Methods with Applications to Clinical Trials surveys and extends current methods for planning and conducting interim analyses. It provides straightforward descriptions of group sequential hypothesis tests in a form suited for direct application to a wide variety of clinical trials. Medical statisticians engaged in any investigations planned with interim analyses will find this book a useful and important tool.
Book Synopsis Phase II Final Report, NATO/CCMS Pilot Study by :
Download or read book Phase II Final Report, NATO/CCMS Pilot Study written by and published by DIANE Publishing. This book was released on 1998 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
