Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations

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Author :
Publisher : National Academies Press
ISBN 13 : 030917452X
Total Pages : 56 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations by : Institute of Medicine

Download or read book Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations written by Institute of Medicine and published by National Academies Press. This book was released on 1997-08-25 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

Drugs and the Elderly

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Author :
Publisher : Springer
ISBN 13 : 134903813X
Total Pages : 293 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis Drugs and the Elderly by : J. Crooks

Download or read book Drugs and the Elderly written by J. Crooks and published by Springer. This book was released on 1979-06-17 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Geriatric Pharmacology

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Author :
Publisher : McGraw-Hill Companies
ISBN 13 :
Total Pages : 708 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Geriatric Pharmacology by : Rubin Bressler

Download or read book Geriatric Pharmacology written by Rubin Bressler and published by McGraw-Hill Companies. This book was released on 1993 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the pharmacokinetic and pharmacodynamic changes of the elderly along with the potential adverse drug reactions to consider, providing guidelines on how these factors affect therapeutic decision making.

Clinical Pharmacology in the Elderly

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642609988
Total Pages : 188 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Clinical Pharmacology in the Elderly by : Hans-Peter Breuel

Download or read book Clinical Pharmacology in the Elderly written by Hans-Peter Breuel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The appropriate and rational use of drugs by the elderly is a matter of growing medical and social concern. Persons aged 65 years and older constitute about 12%-15% of the population in the Western world, and the total number of the elderly will increase significantly in the coming years. This population accounts for 30% of all the prescription drugs used. Aging, specifically the transition from middle to old age, is a complex process. From the perspective of clinical pharmacology, these pathophysiological changes may reasonably be expected to alter responsiveness to drugs. The age-related differences in response to drugs can arise from alterations in pharmacokinetics or pharmacodynamics. This makes it mandatory that clinical pharma cological studies be carried out in the elderly during extended phase I studies. The older the population likely to use the drug, the more important it is to include the very old. It is also important not to exclude .... :''lecessarily patients with concomitant illnesses; it is only by observing, such patients that drug-disease interactions can be detected. Reports from surveillance systems have greatly increased our awareness of problems associated with drug therapy in old age.

Drug-related problems in the elderly

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048124468
Total Pages : 139 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Drug-related problems in the elderly by : Patrik Midlöv

Download or read book Drug-related problems in the elderly written by Patrik Midlöv and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of great importance to all mankind. Drugs are however powerful and must be handled appropriately. This is especially important for elderly patients. Drug-related problem is not a major subject in most university programmes in medicine or pharmacy. When there is no speci c course, there is often no book covering the topic. In our view, as teachers at various university courses, there has been a shortage of literature that re ects the most important aspects of drug-related problems in the elderly. Medical practitioners, nurses and pharmacists, need to have this knowledge to be able to serve their patients in the best way. This book covers most aspects of drug-related problems in the elderly. With b- ter knowledge of drug-related dif culties and risks we hope that elderly will have fewer drug-related problems and bene t more from their pharmacotherapy.

Drugs and the Elderly

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Author :
Publisher :
ISBN 13 : 9780333238004
Total Pages : 304 pages
Book Rating : 4.2/5 (38 download)

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Book Synopsis Drugs and the Elderly by : James Crooks

Download or read book Drugs and the Elderly written by James Crooks and published by . This book was released on 1979 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Geriatric Pharmacotherapy

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Publisher : ASHP
ISBN 13 : 158528436X
Total Pages : 718 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Fundamentals of Geriatric Pharmacotherapy by : Lisa C. Hutchison

Download or read book Fundamentals of Geriatric Pharmacotherapy written by Lisa C. Hutchison and published by ASHP. This book was released on 2015-03-01 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of older patients surge, so too will the medication management challenges pharmacists and other healthcare providers face with this population. Providing care for these often complex cases means not only staying on top of new medications and therapies, but dealing with a wide range of other issues as well. Now in its second edition, Fundamentals of Geriatric Pharmacotherapy, by Lisa C. Hutchison and Rebecca B. Sleeper, offers the full support you need to provide the most effective medication management and therapeutic decisions. This text is unique, not only as a comprehensive overview of major issues in geriatric pharmacotherapy and a core textbook for students, but as a resource for all healthcare professionals who treat elderly patients. Covering all major topics and issues, the second edition provides the most current information and proven strategies in one comprehensive guide, including associated issues that impact therapy, such as the coordination of care across multiple venues and caregivers. Inside this edition, you will find: Summarized treatment guidelines Evidence-based reviews Recommendations for the frail elderly Case studies and clinical pearls Key points, terms, and definitions Self-assessment questions Extensively referenced New chapters on Palliative and Hospice Care and Infections and Antimicrobial Stewardship The demands of an aging population mean that a greater understanding of geriatric pharmacotherapy is now essential for all healthcare providers. Written by practicing geriatric specialists, Fundamentals of Geriatric Pharmacotherapy provides all the detailed information and practical guidance you need.

Geriatric Pharmacology

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Author :
Publisher :
ISBN 13 : 9781683730088
Total Pages : 0 pages
Book Rating : 4.7/5 (3 download)

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Book Synopsis Geriatric Pharmacology by : Steven Atkinson

Download or read book Geriatric Pharmacology written by Steven Atkinson and published by . This book was released on 2016-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Geriatric Pharmacology: The Principles of Practice & Clinical Recommendations is the optimal guide for anyone seeking straightforward, concise and user-friendly information on medication dynamics for older adults. Fully revised and updated, this invaluable resource has become the go-to favorite for healthcare professionals. Here's what you'll find: Learn to manage medication combinations without causing harm How to safely prescribe opioids Avoiding the top 10 most dangerous geriatric drugs Practical guidelines to stop and start prescriptions Drug-drug interaction charts and strategies

Handbook of Pharmacology on Aging

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Author :
Publisher : CRC Press
ISBN 13 : 9780849383069
Total Pages : 398 pages
Book Rating : 4.3/5 (83 download)

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Book Synopsis Handbook of Pharmacology on Aging by : Jay Roberts

Download or read book Handbook of Pharmacology on Aging written by Jay Roberts and published by CRC Press. This book was released on 1996-08-14 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: As adaptive capacities decline, and disease increases, the elderly become major consumers of drugs. Because of the special needs of older patients, physicians, geriatricians, health providers, and researchers must know how the aging process changes the pharmacokinetic and pharmacodynamic properties of drugs prescribed to the elderly. The Second Edition of this essential handbook is an up-to-date source that analyses the major drug groups, the disorders they treat, and the age-associated changes in cellular processes that affect drug action. Disorders prevalent in older people, such as Alzheimer's disease and Parkinson's disease, are examined in great detail. The book also discusses a wide range of drugs, including bronchodilators for asthma, nonsteroid anti-inflammatory drugs for arthritis, antibiotics, and treatments for cardiovascular disease, cancer, and mental disorders. The handbook also provides insight into future research problems dealing with the expanding aging population, their drug usage, and increasing adverse drug reactions.

Clinical Pharmacology in the Elderly

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Author :
Publisher : Springer
ISBN 13 : 9783642609992
Total Pages : 182 pages
Book Rating : 4.6/5 (99 download)

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Book Synopsis Clinical Pharmacology in the Elderly by : Hans-Peter Breuel

Download or read book Clinical Pharmacology in the Elderly written by Hans-Peter Breuel and published by Springer. This book was released on 2014-03-12 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The appropriate and rational use of drugs by the elderly is a matter of growing medical and social concern. Persons aged 65 years and older constitute about 12%-15% of the population in the Western world, and the total number of the elderly will increase significantly in the coming years. This population accounts for 30% of all the prescription drugs used. Aging, specifically the transition from middle to old age, is a complex process. From the perspective of clinical pharmacology, these pathophysiological changes may reasonably be expected to alter responsiveness to drugs. The age-related differences in response to drugs can arise from alterations in pharmacokinetics or pharmacodynamics. This makes it mandatory that clinical pharma cological studies be carried out in the elderly during extended phase I studies. The older the population likely to use the drug, the more important it is to include the very old. It is also important not to exclude .... :''lecessarily patients with concomitant illnesses; it is only by observing, such patients that drug-disease interactions can be detected. Reports from surveillance systems have greatly increased our awareness of problems associated with drug therapy in old age.

Drug Therapy for the Elderly

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Publisher : Springer Science & Business Media
ISBN 13 : 3709109124
Total Pages : 356 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Drug Therapy for the Elderly by : Martin Wehling

Download or read book Drug Therapy for the Elderly written by Martin Wehling and published by Springer Science & Business Media. This book was released on 2012-08-17 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: With people aged 65 years and older currently making up the fastest growing age group throughout the world, the demographic revolution of an aging society will inevitably lead to increased pressure to develop a rationalistic and age-tailored process of diagnosis and treatment among the elderly. As aging people often suffer from several chronic diseases and are being treated with multiple medications concurrently, unwanted drug interactions occur more frequently. Whereas recent approaches have recommended to remove particular drugs from the medication regimen to avoid adverse effects, Drug Therapy for the Elderly underlines both indispensable and dispensable elements of drug treatment in order to provide an overall assessment of drugs suitable for the aged. In view of the multimorbidity and polypharmacy situations experienced by elderly patients, this book takes into account the special needs and requirements shown by this group, thus serving as a timely reference for physicians who treat the elderly.

Anti-Aging Pharmacology

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Publisher : Academic Press
ISBN 13 : 0128236809
Total Pages : 400 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Anti-Aging Pharmacology by : Vitaly Koltover

Download or read book Anti-Aging Pharmacology written by Vitaly Koltover and published by Academic Press. This book was released on 2022-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. Includes updated information about current developments in anti-aging pharmacology Offers practical advice on the applicability of certain healthspan-promoting medications Discusses potential challenges related to the translation of anti-aging drugs in clinical practice

Hearing on Adverse Drug Reactions in the Elderly

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Author :
Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Hearing on Adverse Drug Reactions in the Elderly by : United States. Congress. Senate. Special Committee on Aging

Download or read book Hearing on Adverse Drug Reactions in the Elderly written by United States. Congress. Senate. Special Committee on Aging and published by . This book was released on 1996 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medication-Related Falls in Older People

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Publisher : Springer
ISBN 13 : 3319323040
Total Pages : 255 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Medication-Related Falls in Older People by : Allen R. Huang

Download or read book Medication-Related Falls in Older People written by Allen R. Huang and published by Springer. This book was released on 2016-07-25 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprising a single repository of knowledge and scientific evidence in the field, this book provides strategies to mitigate fall risk by providing information on the complex interactions between aging processes, co-morbid conditions and prescribed medications in older patients. Geriatric health is becoming a more prominent issue as the population ages, and balancing the beneficial effects of medication against the potential and real side-effects in these patients involves a deliberate and thoughtful task: physiologic aging, the accumulation of co-morbidities, and the use of drugs to manage various conditions and symptoms generates a unique set of problems for each patient. Falls are a dreaded event in older people. The event can affect a person in a physical, and psychological manner, resulting in soft tissue and bony injury, fear of falling, and depression. The identification of and reduction in fall risks in older people is a worldwide concern, and reducing the incidence of falls is a ubiquitous quality measure of health care delivery. Heterogeneity amongst older people precludes a single solution. However, physicians and others involved in the care of geriatric patients will benefit from the presented insights into how medication use can be modified to limit its impact as a contributing factor.

HDBK OF PHARMACOLOGY OF AGING

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis HDBK OF PHARMACOLOGY OF AGING by : Jay Roberts

Download or read book HDBK OF PHARMACOLOGY OF AGING written by Jay Roberts and published by Springer. This book was released on 1983 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drugs and Aging

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642707882
Total Pages : 258 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Drugs and Aging by : Dieter Platt

Download or read book Drugs and Aging written by Dieter Platt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental gerontological research is necessary to obtain optimal information and thus ensure proper drug therapy for the elderly. Most older persons acquire multiple diseases, first of all chronic diseases. They involve complex problems of a physical, social, and psychological nature. The multimorbidity of the elderly raises many questions in drug therapy. By contrast with our extensive knowledge of pharmacokinetics and pharmacodynamics in younger age groups, few facts are available in respect of the elderly. A variety of factors may influence drug therapy. Physiological and pathological age-related changes of molecules, cells, organs, and the total organism may interact to enhance or inhibit drug therapy in higher age groups. It is well known that elderly patients are overmedicated and therefore the incidence of adverse drug reactions increases with age. Elderly patients with multimorbidity often have a diminished body clearance of drugs; age-related changes of the kidney seems to be one of the most important factors in this regard. Far less important than the elimination of drugs through the kidney is their excretion in the bile. So far results have disclosed that oxidative steps in drug clearance are more likely to be disturbed than phase II reactions. Furthermore; changes in distribution volume and age-related alterations in receptor sensitivity also influence the clearance of drugs in the elderly.

Prescribing for Elderly Patients

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Author :
Publisher : Wiley
ISBN 13 : 9780470024287
Total Pages : 552 pages
Book Rating : 4.0/5 (242 download)

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Book Synopsis Prescribing for Elderly Patients by : Stephen Jackson

Download or read book Prescribing for Elderly Patients written by Stephen Jackson and published by Wiley. This book was released on 2009-06-29 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for doctors to quickly choose the right drugs in the right dose for the most important clinical problems in the elderly Prescribing medications for elderly patients is complex - this book gives clear advice on treatment regimes, drug interactions, adverse effects, and recommended dose changes Provides practical help with the problems that can arise in reaching an accurate diagnosis in the elderly, recommends clear treatment options, lists key drug interactions and side effects, and advises when to amend doses