Pharmacological Regulation Of Gene Expression In The Cns Towards An Understanding Of Basal Ganglial Functions 1996

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Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996)

Author : Kalpana Merchant
Publisher : CRC Press
ISBN 13 : 1351359517
Total Pages : 336 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996) by : Kalpana Merchant

Download or read book Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996) written by Kalpana Merchant and published by CRC Press. This book was released on 2017-11-22 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters, written by the world's leading scientists, provides an understanding of anatomy, neurochemistry, and cellular and molecular effects. Such an understanding sheds light on the pathophysiology of central disorders involving the basal ganglia and leads to new approaches for the treatment of diseases such as Parkinson's disease and schizophrenia, and also addictions to psychostimulants such as cocaine and amphetamines.

Revival: Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996)

Author : Kalpana Merchant
Publisher : CRC Press Revivals
ISBN 13 : 9781138561120
Total Pages : 224 pages
Book Rating : 4.5/5 (611 download)

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Book Synopsis Revival: Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996) by : Kalpana Merchant

Download or read book Revival: Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996) written by Kalpana Merchant and published by CRC Press Revivals. This book was released on 2019-01-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters, written by the world's leading scientists, provides an understanding of anatomy, neurochemistry, and cellular and molecular effects. Such an understanding sheds light on the pathophysiology of central disorders involving the basal ganglia and leads to new approaches for the treatment of diseases such as Parkinson's disease and schizophrenia, and also addictions to psychostimulants such as cocaine and amphetamines.

Handbook of Basal Ganglia Structure and Function

Author : Heinz Steiner
Publisher : Academic Press
ISBN 13 : 008091215X
Total Pages : 729 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Basal Ganglia Structure and Function by : Heinz Steiner

Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2010-03-17 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

The Primate Nervous System, Part III

Author : Floyd E. Bloom
Publisher : Elsevier
ISBN 13 : 0080539491
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Primate Nervous System, Part III by : Floyd E. Bloom

Download or read book The Primate Nervous System, Part III written by Floyd E. Bloom and published by Elsevier. This book was released on 1999-10-26 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the third and final part of the planned coverage of the neurochemical circuitry of the primate central nervous system. The five chapters included in this volume complement and integrate magnificently with the two prior volumes. Included in the volume are the following: a two-fold exposition on the human forebrain, comprised of a comprehensive overview of the entire human forebrain, and a specific focus on the basal forebrain (a region critical for a wide range of human problems ranging from substance abuse to Alzheimer's disease), a critical synthesis of the primate basal ganglia (a region under intense scrutiny for the organization of motor programs, and for their dysfunctions in Parkinson's disease, Huntington's disease and other malfunctions), the chemical and anatomic details of the primate hippocampal formation in extenso, and lastly, a review of the rapidly growing literature on the mesocortical projection of dopaminergic circuits onto the primate frontal cortex ( a system highly linked to higher order mental abstractions, as well as the dysfunctions of schizophrenia). Scholars will recognize that the laying out of these status reports on our still vastly incomplete examination of the primate brains is an opportunity for progress.

Drugs and the Future

Author : David J. Nutt
Publisher : Elsevier
ISBN 13 : 0080467741
Total Pages : 615 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Drugs and the Future by : David J. Nutt

Download or read book Drugs and the Future written by David J. Nutt and published by Elsevier. This book was released on 2006-12-11 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA

The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

Author : Udo Rüb
Publisher : Springer
ISBN 13 : 331919285X
Total Pages : 154 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy by : Udo Rüb

Download or read book The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy written by Udo Rüb and published by Springer. This book was released on 2015-09-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Basal Ganglia Circuits

Author : Jose L. Lanciego
Publisher : Frontiers E-books
ISBN 13 : 2889190196
Total Pages : 214 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Basal Ganglia Circuits by : Jose L. Lanciego

Download or read book Basal Ganglia Circuits written by Jose L. Lanciego and published by Frontiers E-books. This book was released on with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current basal ganglia model has been introduced 25 years ago and has settled the basis for most of our current understanding of Parkinson's disease. Despite the tremendous success of the model, a number of experimental evidences have been made available over the past 25 years and the "classical" basal ganglia model is somewhat obsolete. I believe that it would be possible to recruit a number of international leading experts that have generated new data on basal ganglia circuits and therefore a Research Topic of this kind would lead to the introduction of a fully updated basal ganglia model, incorporating all the new basal ganglia circuits that have been characterized over the past 25 years.

Pharmacology of Ionic Channel Function: Activators and Inhibitors

Author : M. Endo
Publisher : Springer Science & Business Media
ISBN 13 : 3642570836
Total Pages : 674 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Pharmacology of Ionic Channel Function: Activators and Inhibitors by : M. Endo

Download or read book Pharmacology of Ionic Channel Function: Activators and Inhibitors written by M. Endo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells maintain uneven distribution of Na, K and Ca ions across the cell membrane and membranes of intracellular organellae. Cells exert their functions by allowing for some ion to cross the membrane through ion channels which either produces an electrical effect across the membrane or switches on a series of chemical or physicochemical reactions. This is a comprehensive book about these vitally important ion channels with detailed description of the molecular structure and function and especially of activators and inhibitors. All chapters are written by renowned specialists in their field.

Brain Dynamics and the Striatal Complex

Author : Robert Miller
Publisher : CRC Press
ISBN 13 : 0203304918
Total Pages : 324 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Brain Dynamics and the Striatal Complex by : Robert Miller

Download or read book Brain Dynamics and the Striatal Complex written by Robert Miller and published by CRC Press. This book was released on 2003-09-02 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Dynamics and the Striatal Complex, the first volume in the Conceptual Advances in Brain Research book series, relates dynamic function to cellular structure and synaptic organization in the basal ganglia. The striatum is the largest nucleus within the basal ganglia and therefore plays an important role in understanding structure/function relationships. Areas covered include dopaminergic input to the striatum, organization of the striatum, and the interaction between the striatum and the cerebral cortex.

Functional Neuroanatomy

Author : N. J. Strausfeld
Publisher : Springer Science & Business Media
ISBN 13 : 3642821154
Total Pages : 445 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Functional Neuroanatomy by : N. J. Strausfeld

Download or read book Functional Neuroanatomy written by N. J. Strausfeld and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "functional" in the title of this book not only reflects my personal bias about neuroanatomy in brain research, it is also the gist of many chapters which describe sophisticated ways to resolve structures and interpret them as dynamic entities. Examples are: the visualization of functionally identified brain areas or neurons by activity staining or intracellular dye-iontophoresis; the resolution of synaptic connections between physiologically identified nerve cells; and the biochemical identification of specific neurons (their peptides and transmitters) by histo- and immunocytochemistry. I personally view the nervous system as an organ whose parts, continuously exchanging messages, arrive at their decisions by the cooperative phenome non of consensus and debate. This view is, admittedly, based on my own ex perience of looking at myriads of nerve cells and their connections rather than studying animal behaviour or theorizing. Numerous structural studies have demonstrated that interneurons in the brain must receive hundreds of thousands of synapses. Many neurons receive inputs from several different sensory areas: each input conveys a message about the external world and possibly also about past events which are stored within the central nervous system. Whether an interneuron responds to a certain combination of inputs may be, literally, a matter of debate whose outcome is decided at the post synaptic membrane. A nerve cell responding to an overriding command is possibly a rare event.

The pharmacotherapy of depression - searching for new mechanisms and drug interactions. Basic and clinical research.

Author : Katarzyna Stachowicz
Publisher : Frontiers Media SA
ISBN 13 : 2832510434
Total Pages : 197 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The pharmacotherapy of depression - searching for new mechanisms and drug interactions. Basic and clinical research. by : Katarzyna Stachowicz

Download or read book The pharmacotherapy of depression - searching for new mechanisms and drug interactions. Basic and clinical research. written by Katarzyna Stachowicz and published by Frontiers Media SA. This book was released on 2023-01-02 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurological Aspects of Substance Abuse

Author : John Calvin M. Brust
Publisher : Butterworth-Heinemann
ISBN 13 : 9780750673136
Total Pages : 504 pages
Book Rating : 4.6/5 (731 download)

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Book Synopsis Neurological Aspects of Substance Abuse by : John Calvin M. Brust

Download or read book Neurological Aspects of Substance Abuse written by John Calvin M. Brust and published by Butterworth-Heinemann. This book was released on 2004 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2nd Edition of this comprehensive text features practical guidance on how to diagnose and manage the neurological effects and complications of every major category of recreationally used drugs. Book jacket.

Basal Ganglia X - Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society

Author : Charles J. Wilson
Publisher : Frontiers E-books
ISBN 13 : 2889190366
Total Pages : 456 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Basal Ganglia X - Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society by : Charles J. Wilson

Download or read book Basal Ganglia X - Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society written by Charles J. Wilson and published by Frontiers E-books. This book was released on with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains articles describing research on the basic, pre-clinical and clinical neuroscience of the basal ganglia written by attendees of the 10th Triennial Meeting of the International Basal Ganglia Society (IBAGS) that was held June 20-24th, 2010 at the Ocean Place Resort in Long Branch, New Jersey, USA. For each of the preceding 9 IBAGS meetings, the meeting proceedings were published conventionally as a volume in the Advances in Behavioral Biology series. These volumes were expensive, were published only in very small quantities, had very limited availability to both basal ganglia researchers and the general neuroscience community, were not available on-line and the articles contained in each were not indexed in online searchable databases. Now, for the first time, IBAGS is taking full advantage of modern innovations in scientific publication and publishing IBAGS X as a Research Topics issue of Frontiers in Systems Neuroscience. The issue will be available on-line and is fully indexed by searchable databases including PubMed. Articles will include reports on the latest research on the anatomy and neurophysiology of single neurons and functional circuitry in the striatum, globus pallidus, subthalamic nucleus and substantia nigra as well as the latest data on animal models of basal ganglia dysfunction as well as behavioral and clinical studies in human patients.

The Brain and Behavior

Author : David L. Clark
Publisher : Cambridge University Press
ISBN 13 : 9780521840507
Total Pages : 290 pages
Book Rating : 4.8/5 (45 download)

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Book Synopsis The Brain and Behavior by : David L. Clark

Download or read book The Brain and Behavior written by David L. Clark and published by Cambridge University Press. This book was released on 2005-09-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.

Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy

Author : F.W. Van Leeuwen
Publisher : Elsevier
ISBN 13 : 008086242X
Total Pages : 551 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy by : F.W. Van Leeuwen

Download or read book Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy written by F.W. Van Leeuwen and published by Elsevier. This book was released on 1998-11-09 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Academy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases. The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries.

Massachusetts General Hospital Psychopharmacology and Neurotherapeutics E-Book

Author : Theodore A. Stern
Publisher : Elsevier Health Sciences
ISBN 13 : 0323413234
Total Pages : 256 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Massachusetts General Hospital Psychopharmacology and Neurotherapeutics E-Book by : Theodore A. Stern

Download or read book Massachusetts General Hospital Psychopharmacology and Neurotherapeutics E-Book written by Theodore A. Stern and published by Elsevier Health Sciences. This book was released on 2015-04-27 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Put today's best approaches to work for your patients with this practical guide to cutting-edge psychopharmacologic and somatic treatments for psychiatric and neurologic conditions. Edited by Drs. Theodore A. Stern, Maurizio Fava, Timothy E. Wilens, and Jerrold F. Rosenbaum, and comprised of key chapters from the second edition of Stern et al.’s Massachusetts General Hospital Comprehensive Clinical Psychiatry, this user-friendly resource focuses on current psychotropic treatments, electroconvulsive therapy, and neurotherapeutics, making it an ideal quick reference for psychiatrists, psychologists, internists, and nurse practitioners. Stay current with hot topics in the field, including the use of antiepileptic drugs in psychiatry, ADHD medications, and often-overlooked areas such as treatment of pain. Benefit from the authoritative content of the parent text, MGH Comprehensive Clinical Psychiatry, 2nd Edition, now featuring new art, new tables, and key points, and updated to DSM-5 where relevant. Get detailed coverage of antidepressants, antipsychotics, and antianxiety medications, as well as drug interactions, side effects, and treatment adherence. Quickly find the information you need with a user-friendly, highly templated format that features abundant boxed summaries, bulleted points, case histories, algorithms, references, and suggested readings. Test your knowledge of psychopharmacology and neurotherapeutics with interactive, downloadable multiple-choice questions with detailed answers for each chapter.