Pharmacological Control Of Calcium And Potassium Homeostasis

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Pharmacological Control of Calcium and Potassium Homeostasis

Author : T. Godfraind
Publisher : Springer Science & Business Media
ISBN 13 : 9401101175
Total Pages : 280 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Pharmacological Control of Calcium and Potassium Homeostasis by : T. Godfraind

Download or read book Pharmacological Control of Calcium and Potassium Homeostasis written by T. Godfraind and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of drugs acting on calcium and potassium channels grows, there is a need for a continuous reappraisal of the cellular machinery controlling them. The present volume provides an update on the basic knowledge, the molecular targets of the two channels, and the importance the drugs that bind them have as pharmacological tools and therapeutic agents. This work was presented at the 6th International Symposium on PHARMACOLOGICAL CONTROL OF CALCIUM AND POTASSIUM HOMEOSTASIS: BIOLOGICAL, THERAPEUTICAL, AND CLINICAL ASPECTS, in Florence (Italy) on October 4-6, 1994. Because of the recent advances in the field, discussions on potassium channels were included for the first time. At least six classes of voltage-dependent calcium channels have been defined based on their physiological and pharmacological properties. Among them, L-type channels, mediating long lasting currents, are better characterized. Calcium homeostasis within the cell is not only regulated by calcium channels; intracellular calcium stores, in particular a pool contained in the lumen of specialized areas of the endoplasmic reticulum, are rapidly exchanged with the cytoplasm and playa key role in the control of calcium homeostasis. This area, however, has not yet been exploited from a therapeutic point of view. Potassium channels are present in virtually every cell type, excitable and nonexcitable, and are distinguished by structural, biophysical, and pharmacological criteria. Different classes including voltage-gated, ligand-gated, AP-sensitive, and G-protein coupled among others, have been defined by their primary regulatory and gating mechanisms.

Molecular and Cellular Mechanisms of Cardiovascular Regulation

Author : Hasso 04Scholz
Publisher : Springer Science & Business Media
ISBN 13 : 4431659528
Total Pages : 445 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Molecular and Cellular Mechanisms of Cardiovascular Regulation by : Hasso 04Scholz

Download or read book Molecular and Cellular Mechanisms of Cardiovascular Regulation written by Hasso 04Scholz and published by Springer Science & Business Media. This book was released on 2013-12-14 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains selected papers presented at the Sendai International Sympo sium on Molecular and Cellular Mechanisms of Cardiovascular Regulation held from May 10-12, 1995, to honor the contributions ofProfessorNorio Taira, Chairman of the Department of Pharmacology (1972-1995), Tohoku University School of Medicine, Sendai, Japan. The Department of Pharmacology at Sendai has a long tradition of significant contribution to the development of drug therapy for cardiovascular diseases. The late Professor Koroku Hashimoto, the predecessor of Professor Norio Taira, first suggested the mode of action of calcium antagonists and their potential usefulness in therapy of ischemic heart disease and hypertension at an early stage of their development. The need for greater understanding of the pathophysiology of cardiovascular dis eases is more critical now than ever before because modern advances in basic and clinical sciences have prolonged the average life expectancy. Using a wide range of molecular and electrophysiological techniques, major advances are occurring frequently in the field of cardiovascular physiology and pharmacology. Such multifaceted approaches are preferred because human cardiovascular diseases are complex, requiring multiple interventions and an in-depth understanding of molecular mechanisms underlying the disease. The first section of this book focuses on molecular mechanisms of ion channel regulation. Eight of ten chapters in this section are devoted to the recent advances in molecular characterization and regulation of various types of potassium channels in cardiac, vascular, and neuronal tissues. A discussion of the structure and function of sodium and calcium channels is also included.

Women’s Health and Menopause

Author : Rodolfo Paoletti
Publisher : Springer Science & Business Media
ISBN 13 : 0585379734
Total Pages : 292 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis Women’s Health and Menopause by : Rodolfo Paoletti

Download or read book Women’s Health and Menopause written by Rodolfo Paoletti and published by Springer Science & Business Media. This book was released on 2007-07-11 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The population structure in the world is rapidly changing, to the extent that in 75 years we will face a tripling of the elderly population. Although women are favored in terms of life expectancy, they also live with a longer period of disability (approximately twice that of aging men), as well as with the enemies of all the elderly, cardiovascular disease, cancer, and dementia. Menopause is the endocrine event that overlaps with aging, potentially worsening both the quality of life and the risks of disease in women.While the effect of hormone replacement therapy (HRT) on menopausal symptoms is generally viewed as rapid and consistent, and is thereby accepted by the scientific community, its relationship to the other aforementioned chronic conditions associated with menopause is considered variable and controversial.In analyzing these complex issues, this volume yields new and significant insights into both the study of menopause-related disorders and their treatment, by illustrating the most recent information on mechanisms of actions of new estrogen receptors and on the use of sophisticated techniques of statistical analysis for population-based studies.

Multiple Risk Factors in Cardiovascular Disease

Author : Antonio M. Gotto Jr.
Publisher : Springer Science & Business Media
ISBN 13 : 9401150222
Total Pages : 370 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Multiple Risk Factors in Cardiovascular Disease by : Antonio M. Gotto Jr.

Download or read book Multiple Risk Factors in Cardiovascular Disease written by Antonio M. Gotto Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of the most significant contributions to the 4th International Symposium on MULTIPLE RISK FACTORS IN CARDIOVASCULAR DISEASE: STRATEGIES OF PREVENTION OF CORONARY HEART DISEASE, CARDIAC F AlLURE, AND STROKE held in Washington, D. C. in April 1997. The meeting focused on the risk factors for cardiovascular disease and their interactions. The need for this symposium is based on the epidemiological, clinical, and biological evidence that individuals from industrialized countries often possess two or more risk factors which synergistically increase the global risk profile. This has become more evident in recent years with the increase in life expectancy of populations in the industrialized countries. The evidence that a combination of risk factors confers a very high risk of developing cardiovascular diseases, is of pivotal interest in the process of detection of patients who will benefit the most from pharmacological treatment. Many recent epidemiological data identifying the intrinsic and environmental factors contributing to the development of atherosclerosis are discussed. These results, in parallel with basic and clinical research, underline atherosclerosis as a complex and multifactorial process involving the influences of lipids, including lipoprotein subfractions, blood pressure rheologic forces, carbohydrate tolerance, and thrombogenic factors, including fibrinogen, tissue factor, PAl-I, and homocysteine. Furthennore, the risk associated with anyone of these risk factors varies widely depending on the level of the associated atherogenic risk factors. Hyper cholesterolemia and hypertriglyceridemia, for instance, are more common than would be expected by chance among hypertensive patients.

Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

Author : J.-C. Fruchart
Publisher : Springer Science & Business Media
ISBN 13 : 9781402071997
Total Pages : 196 pages
Book Rating : 4.0/5 (719 download)

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Book Synopsis Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications by : J.-C. Fruchart

Download or read book Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications written by J.-C. Fruchart and published by Springer Science & Business Media. This book was released on 2002-11-30 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a fast pace and PPARs have become an interesting target for the treatment of many pathological conditions, including diabetes and atherosclerosis. This volume provides an authoritative view of the current clinical and scientific developments within this evolving area of study.

Advances in Prostaglandin and Leukotriene Research

Author : Bengt Samuelsson
Publisher : Springer Science & Business Media
ISBN 13 : 9781402001468
Total Pages : 236 pages
Book Rating : 4.0/5 (14 download)

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Book Synopsis Advances in Prostaglandin and Leukotriene Research by : Bengt Samuelsson

Download or read book Advances in Prostaglandin and Leukotriene Research written by Bengt Samuelsson and published by Springer Science & Business Media. This book was released on 2002-01-31 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the proceedings of the 11th International Conference on Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications, held in Florence, Italy, on June 4-8, 2000, which continues the tradition of covering both basic and clinical aspects of prostaglandin and leukotriene research. At this meeting particular emphasis was given to the potential application of the novel COX-2 inhibitors, the genetics of asthma relating to the production of leukotrienes, and novel cellular networks for the production of leukotrienes and lipoxins. Traditionally, as has been done in past meetings of this series, a considerable amount of new material was presented and discussed this year, with particular attention given to the newest clinical data.

Oxford Textbook of Clinical Nephrology

Author : Neil N. Turner
Publisher : Oxford University Press
ISBN 13 : 0191017655
Total Pages : 3045 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Clinical Nephrology by : Neil N. Turner

Download or read book Oxford Textbook of Clinical Nephrology written by Neil N. Turner and published by Oxford University Press. This book was released on 2015-10-29 with total page 3045 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309091586
Total Pages : 639 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate by : Institute of Medicine

Download or read book Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate written by Institute of Medicine and published by National Academies Press. This book was released on 2005-06-18 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate The Dietary Reference Intakes (DRIs) are quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. This new report, the sixth in a series of reports presenting dietary reference values for the intakes of nutrients by Americans and Canadians, establishes nutrient recommendations on water, potassium, and salt for health maintenance and the reduction of chronic disease risk. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate discusses in detail the role of water, potassium, salt, chloride, and sulfate in human physiology and health. The major findings in this book include the establishment of Adequate Intakes for total water (drinking water, beverages, and food), potassium, sodium, and chloride and the establishment of Tolerable Upper Intake levels for sodium and chloride. The book makes research recommendations for information needed to advance the understanding of human requirements for water and electrolytes, as well as adverse effects associated with the intake of excessive amounts of water, sodium, chloride, potassium, and sulfate. This book will be an invaluable reference for nutritionists, nutrition researchers, and food manufacturers.

Pediatric Nephrology

Author : Ellis D. Avner
Publisher : Springer Science & Business Media
ISBN 13 : 3540763279
Total Pages : 2059 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Pediatric Nephrology by : Ellis D. Avner

Download or read book Pediatric Nephrology written by Ellis D. Avner and published by Springer Science & Business Media. This book was released on 2009-08-20 with total page 2059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.

Cardiovascular Biology of Purines

Author : Geoffrey Burnstock
Publisher : Springer Science & Business Media
ISBN 13 : 1461556031
Total Pages : 386 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cardiovascular Biology of Purines by : Geoffrey Burnstock

Download or read book Cardiovascular Biology of Purines written by Geoffrey Burnstock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following many years when a great deal of attention was directed towards the intracellular roles of purines, there is expanding interest in the field of extracellular purinergic signalling. In this book we focus on the actions of purines in cardiovascular biology, where it is clear that they play major roles in both normal and pathophysiological conditions. Activation of different purinoceptor subtypes by purines can regulate cardiac contractility and electrical activity, modulate catecholamine-mediated responses both pre- and post-junctionally, trigger and mediate ischaemic preconditioning, cause vasodilation and vasoconstriction and enhance endothelial proliferation and apoptosis as well as inhibit platelet and neutrophil function. This book covers the cardiovascular actions mediated by the major P1 and P2 subclasses of purinoceptors and emphasizes the interactions between these two signalling systems. Cardiovascular Biology of Purines covers topics ranging from molecular and cellular to systemic and clinical. It also aims to highlight how basic advances have led to the identification of novel targets for cardiovascular therapeutic developments. We hope that our book will prove to be timely and helpful.

Neuroprotective Agents and Cerebral Ischaemia

Author :
Publisher : Academic Press
ISBN 13 : 9780080857749
Total Pages : 378 pages
Book Rating : 4.8/5 (577 download)

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Book Synopsis Neuroprotective Agents and Cerebral Ischaemia by :

Download or read book Neuroprotective Agents and Cerebral Ischaemia written by and published by Academic Press. This book was released on 1996-11-26 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes. Stroke is the third major cause of death in the western world, and recent data provide hope that treatments may soon be available. Written by world experts on the mechanisms involved in neurodegeneration, Neuroprotective Agents and Cerebral Ischaemia presents an up-to-date review of current research and developing therapies. This book is essential reading for all clinicians and researchers searching for neuroprotective drugs. Describes the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode Presents the different factors affecting the neurodegenerative process and how compounds acting on these systems may lead to novel neuroprotective agents Reviews in vitro and in vivo models of stroke and the activity of putative neuroprotective drugs Discusses the application of preclinical data to formulate approaches to a clinical problem Provides detailed reviews of both completed clinical trials and those currently underway

The Cumulative Book Index

Author :
Publisher :
ISBN 13 :
Total Pages : 2230 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cumulative Book Index by :

Download or read book The Cumulative Book Index written by and published by . This book was released on 1996 with total page 2230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.

Side Effects of Drugs Annual

Author :
Publisher : Elsevier
ISBN 13 : 044463889X
Total Pages : 604 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Side Effects of Drugs Annual by :

Download or read book Side Effects of Drugs Annual written by and published by Elsevier. This book was released on 2016-10-25 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions was first published in 1977, and has been continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each annual provides clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing their expertise each year. Provides a critical yearly survey of the new data and trends regarding the side effects of drugs Authored and reviewed by worldwide pioneers in the clinical and practice sciences Presents an essential clinical on the side effects of drugs for practitioners and healthcare professionals alike

Stoelting's Handbook of Pharmacology and Physiology in Anesthetic Practice

Author : Robert Stoelting
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469890755
Total Pages : 700 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Stoelting's Handbook of Pharmacology and Physiology in Anesthetic Practice by : Robert Stoelting

Download or read book Stoelting's Handbook of Pharmacology and Physiology in Anesthetic Practice written by Robert Stoelting and published by Lippincott Williams & Wilkins. This book was released on 2014-12-05 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get trusted anesthesiology guidance in a compact, high-yield source with Stoelting’s Handbook of Pharmacology and Physiology in Anesthetic Practice. Updated from the Fifth Edition of Stoelting's Pharmacology and Physiology in Anesthetic Practice, this handbook provides succinct, current, and accurate information on the pharmacology and physiology that are relevant to anesthesiology, equipping you to deliver safe and effective perioperative patient management.

Acid-base and Potassium Homeostasis

Author : Barry M. Brenner
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Acid-base and Potassium Homeostasis by : Barry M. Brenner

Download or read book Acid-base and Potassium Homeostasis written by Barry M. Brenner and published by . This book was released on 1978 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacotherapy Handbook

Author : Barbara G. Wells
Publisher : McGraw Hill Professional
ISBN 13 : 9780071433228
Total Pages : 966 pages
Book Rating : 4.4/5 (332 download)

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Book Synopsis Pharmacotherapy Handbook by : Barbara G. Wells

Download or read book Pharmacotherapy Handbook written by Barbara G. Wells and published by McGraw Hill Professional. This book was released on 2005 with total page 966 pages. Available in PDF, EPUB and Kindle. Book excerpt: BONE AND JOINT DISORDERS Edited by Terry L. Schwinghammer 1. Gout and Hyperuricemia 2. Osteoarthritis 3. Osteoporosis 4. Rheumatoid Arthritis CARDIOVASCULAR DISORDERS Edited by Terry L. Schwinghammer 5. Arrhythmias 6. Cardiopulmonary Resuscitation 7. Heart Failure 8. Hyperlipidemia 9.

Pharmacology

Author : Bhattacharya
Publisher : Elsevier India
ISBN 13 : 9788181470096
Total Pages : 634 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Pharmacology by : Bhattacharya

Download or read book Pharmacology written by Bhattacharya and published by Elsevier India. This book was released on 2003 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition of Pharmacology has been thoroughly revised and updated to conform to the recommendations of the MCI regarding the teaching of pharmacology, and to include the latest developments in pharmacology and drug treatment modalities. Special emphasis has been laid on essential and commonly used drugs . WHO and national government recommendations in the drug treatment of prevalent problematic but preventable and treatable diseases responsible for wide scale morbidity and mortality, common poisonings, addictions and rational use of drugs in special situations, e.g. pregnancy, lactation, infancy and old age and in the presence of hepatic and renal dysfunction. Rational Use of Drugs (RUD) and Essential Drugs Programme (EDP) have been discussed, and their importance has been emphasized. Government of India s Essential Drug List (EDL) has been included. A chapter on Clinical Pharmacology and Prescription Writing has been added. About the Author : - Salil K Bhattacharya MD, PhD, FCAI, FAMS, FIBRO, Emeritus Scientist (ICMR), Department of Pharmacology, Postgraduate Institute of Basic Medical Sciences, Calcutta University, Kolkata, India; Formerly, Professor and Head, Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.