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Pharmacogenomics And Precision Medicine An Issue Of The Clinics In Laboratory Medicine
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Book Synopsis Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine by : Kristen Reynolds
Download or read book Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine written by Kristen Reynolds and published by Elsevier Health Sciences. This book was released on 2016-08-16 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.
Book Synopsis Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine by : Ryan J. Schmidt
Download or read book Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine written by Ryan J. Schmidt and published by Elsevier Health Sciences. This book was released on 2020-06-21 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine will cover Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies. Curated by Dr. Ryan J. Schmidt, this issue is one of four selected each year by the series Consulting Editor, Milenko Tanasijevic. The volume will include articles on: Features of a Comprehensive Precision Medicine Program for Constitutional Genetic Disorders, Establishing a Precision Medicine Center of Excellence for Rare Disease, High-throughput DNA Sequencing for Rare Disease Diagnosis, Enhancing Diagnosis through RNA Sequencing, Interpretation of Rare Genetic Variants, Clinical Bioinformatics, Precision Therapies for Retinal Dystrophy, Precision Therapies for Muscular Dystrophy, Therapeutic Gene Editing, High Throughput Functional Studies of Genetic Variants, and Patient-specific Disease Models.
Book Synopsis Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book by : Gregory J. Tsongalis
Download or read book Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book written by Gregory J. Tsongalis and published by Elsevier Health Sciences. This book was released on 2022-11-12 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4 by : Gregory J. Tsongalis
Download or read book Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4 written by Gregory J. Tsongalis and published by Elsevier. This book was released on 2022-11-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Pharmacogenomic Testing in Current Clinical Practice by : Alan H. B. Wu
Download or read book Pharmacogenomic Testing in Current Clinical Practice written by Alan H. B. Wu and published by Springer Science & Business Media. This book was released on 2011-02-08 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.
Book Synopsis Pharmacogenetics by : Kristen K. Reynolds
Download or read book Pharmacogenetics written by Kristen K. Reynolds and published by W B Saunders Company. This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications in Pharmacogenetics are breaching the laboratory medicine and clinical environment. The testing of genetic variations in relation to differing response to drug metabolism and improvement of drug safety is an important and essential area in light of adverse drug reactions. This timely and comprehensive issue of the Clinics presents topics related to Pharmacology and Genetics, Pharmacogenetic Applications in Anticoagulation, Oncology, Pain Management, and Behavioral Disorders, Respiratory Disorders, as well as Education and Healthcare Economics of Pharmacogenetics.
Book Synopsis Pharmacogenomics in Clinical Therapeutics by : Loralie J. Langman
Download or read book Pharmacogenomics in Clinical Therapeutics written by Loralie J. Langman and published by John Wiley & Sons. This book was released on 2012-01-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.
Book Synopsis Pharmacogenomics of Alcohol and Drugs of Abuse by : Amitava Dasgupta
Download or read book Pharmacogenomics of Alcohol and Drugs of Abuse written by Amitava Dasgupta and published by CRC Press. This book was released on 2019-08-30 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.
Book Synopsis Pharmacogenomics in Precision Medicine by : Weimin Cai
Download or read book Pharmacogenomics in Precision Medicine written by Weimin Cai and published by Springer Nature. This book was released on 2020-06-12 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
Book Synopsis Quantitative Methods for Precision Medicine by : Rongling Wu
Download or read book Quantitative Methods for Precision Medicine written by Rongling Wu and published by C&h/CRC Press. This book was released on 2022-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Modern medicine is undergoing a paradigm shift from a "one-size-fits-all" strategy to a more precise patient-customized therapy and medication plan. While the success of precision medicine relies on the level of pharmacogenomic knowledge, dissecting the genetic mechanisms of drug response in a sufficient detail requires powerful computational tools. Quantitative Methods for Precision Medicine: Pharmacogenomics in Action presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. Beyond traditional reductionist-based statistical genetic approaches, statistical formulization in this book synthesizes elements of multiple disciplines to infer, visualize, and track how pharmacogenes interact together as an intricate but well-coordinated system to mediate patient-specific drug response. Features: Functional and systems mapping models to characterize the genetic architecture of multiple medication processes Statistical methods for analyzing informative missing data in pharmacogenetic association studies Functional graph theory of inferring genetic interaction networks from association data Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties Modeling gene-induced cell-cell crosstalk and its impact on drug response A graph model of drug-drug interactions in combination therapies Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine This book is suitable for graduate students and researchers in the field of biology, medicine, bioinformatics and drug design and delivery interested in statistical and computational modelling of biological processes and systems. It may also serve as a major reference for applied mathematicians, computer scientists, and statisticians who attempt to develop algorithmic tools for genetic mapping, systems pharmacogenomics and systems biology. It can be used as both a textbook and research reference. It can also be used by professionals in pharmaceutical sectors who design drugs and by clinical doctors who deliver drugs"--
Book Synopsis Pharmacogenomics in Drug Discovery and Development by : Qing Yan
Download or read book Pharmacogenomics in Drug Discovery and Development written by Qing Yan and published by Springer Nature. This book was released on 2022-09-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.
Book Synopsis Toxicology and Drug Testing, An Issue of Clinics in Laboratory Medicine, E-Book by : Martin H. Bluth
Download or read book Toxicology and Drug Testing, An Issue of Clinics in Laboratory Medicine, E-Book written by Martin H. Bluth and published by Elsevier Health Sciences. This book was released on 2016-11-16 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, edited by Dr. Martin Bluth, will cover a wide array of topics related to drug testing and toxicology. Experts will discuss common drugs in analgesia, toxicology techniques, errors and interferences in toxicology testing, toxicology considerations in pain and addiction medicine, toxicology in reproductive endocrinology, forensic toxicology, and toxicology in emergency medicine, among others.
Book Synopsis Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook by : Martin H. Bluth
Download or read book Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook written by Martin H. Bluth and published by Elsevier Health Sciences. This book was released on 2018-05-23 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology in Transfusion Medicine; Molecular Diagnosis of Hematopoietic Neoplasms; Molecular Diagnostics in Colorectal Carcinoma; Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix; Molecular Diagnostics in Esophageal and Gastric Neoplasms; Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract; Current Applications of Molecular Genetic Technologies to the Diagnosis and Treatment of Cutaneous Melanocytic Neoplasms; Breast Carcinoma; and Gynecologic Cancers.
Book Synopsis Emerging Pathogens, An Issue of Clinics in Laboratory Medicine, E-Book by : Nahed Ismail
Download or read book Emerging Pathogens, An Issue of Clinics in Laboratory Medicine, E-Book written by Nahed Ismail and published by Elsevier Health Sciences. This book was released on 2017-06-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, edited by Drs. Nahed Ismail, A. William Pasculle, and James Snyder, will cover a wide variety of Emerging Pathogens. Topics covered in this issue include, but are not limited to West Nile Virus; Zika Virus; Ebola and Marburg Heamorrhagic Fever; Rift Valley Fever; Carbapenem Resistant Enterobacteriacae; Closteridium Difficuile; and Chikungunya, among others.
Book Synopsis Toxicology Testing, An Issue of Clinics in Laboratory Medicine by : Michael G. Bissell
Download or read book Toxicology Testing, An Issue of Clinics in Laboratory Medicine written by Michael G. Bissell and published by Elsevier Health Sciences. This book was released on 2012-09-28 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.
Book Synopsis Breast Pathology, An Issue of Surgical Pathology Clinics by : Laura C. Collins
Download or read book Breast Pathology, An Issue of Surgical Pathology Clinics written by Laura C. Collins and published by Elsevier Health Sciences. This book was released on 2018-02-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics, edited by Dr. Laura C. Collins, will focus on Breast Pathology. Topics include, but are not limited to: Core needle biopsy of the breast, Mucinous Lesions of the Breast: Pragmatic approach to fibroepithelial lesions; Lymph node inclusions; Differential diagnosis of benign spindle cell lesions of the breast; Ancillary Prognostic and Predictive Testing in Breast Cancer; Lesions of the Low Grade Breast Neoplasia Pathway; Genotype-Phenotype Correlation in Breast Neoplasia; Lobular Carcinoma in Situ; and Processing and Reporting of Breast Specimens in the Neoadjuvant Setting.
Book Synopsis Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology, An Issue of the Clinics in Laboratory Medicine, E-Book by : James O. Westgard
Download or read book Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology, An Issue of the Clinics in Laboratory Medicine, E-Book written by James O. Westgard and published by Elsevier Health Sciences. This book was released on 2017-02-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine entitled “Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology will be guest edited by Sten Westgard, James Westgard, and David Armbruster. The issue will cover a broad range of topics related to management in the laboratory including but not limited to: Metrology Perspectives; Biologic Variation Approach to Daily Laboratory; Clinical Outcome Approach to Goal Setting; Six Sigma Quality Management System; Traceability and Comparability; MU, Risk, and Sigma-metrics at Sunway; and Quality Indicators for the Total Testing Process, among others.
