Pharmaceutical Science Series

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An Introduction to Pharmaceutical Sciences

Author : Jiben Roy
Publisher : Elsevier
ISBN 13 : 1908818042
Total Pages : 449 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis An Introduction to Pharmaceutical Sciences by : Jiben Roy

Download or read book An Introduction to Pharmaceutical Sciences written by Jiben Roy and published by Elsevier. This book was released on 2011-07-25 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. - Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions - Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes - Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries

Introduction to the Pharmaceutical Sciences

Author : Nita K. Pandit
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781744784
Total Pages : 419 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Introduction to the Pharmaceutical Sciences by : Nita K. Pandit

Download or read book Introduction to the Pharmaceutical Sciences written by Nita K. Pandit and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes. Each chapter includes chapter outlines and critical-thinking exercises, as well as numerous tables and graphs. More than 160 illustrations complement the text.

Formulating Poorly Water Soluble Drugs

Author : Robert O. Williams III
Publisher : Springer Science & Business Media
ISBN 13 : 1461411440
Total Pages : 656 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Formulating Poorly Water Soluble Drugs by : Robert O. Williams III

Download or read book Formulating Poorly Water Soluble Drugs written by Robert O. Williams III and published by Springer Science & Business Media. This book was released on 2011-12-04 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds. Further, this book is designed to provide practical guidance for overcoming formulation challenges toward the end goal of improving drug therapies with poorly water-soluble drugs. Enhancing solubility via formulation intervention is a unique opportunity in which formulation scientists can enable drug therapies by creating viable medicines from seemingly undeliverable molecules. With the ever increasing number of poorly water-soluble compounds entering development, the role of the formulation scientist is growing in importance. Also, knowledge of the advanced analytical, formulation, and process technologies as well as specific regulatory considerations related to the formulation of these compounds is increasing in value. Ideally, this book will serve as a useful tool in the education of current and future generations of scientists, and in this context contribute toward providing patients with new and better medicines.

Remington

Author : Adeboye Adejare
Publisher : Academic Press
ISBN 13 : 0128223898
Total Pages : 1032 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Remington by : Adeboye Adejare

Download or read book Remington written by Adeboye Adejare and published by Academic Press. This book was released on 2020-11-03 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics. - Contains a comprehensive source of principles of drug discovery and development topics, especially for scientists that are new in the pharmaceutical industry such as those with trainings/degrees in chemistry and engineering - Provides a detailed source for formulation scientists and compounding pharmacists, from produg to excipient issues - Updates this excellent source with the latest information to verify facts and refresh on basics for professionals in the broadly defined pharmaceutical industry

Statistical Methodology in the Pharmaceutical Sciences

Author : D. A. Berry
Publisher : CRC Press
ISBN 13 : 1482276860
Total Pages : 592 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Statistical Methodology in the Pharmaceutical Sciences by : D. A. Berry

Download or read book Statistical Methodology in the Pharmaceutical Sciences written by D. A. Berry and published by CRC Press. This book was released on 2016-04-19 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art handbook of statistical analysis for use in the pharmaceutical industry. Areas covered in this reference/text include: bioavailability, repeated-measures designs, dose-response, population models, multicenter trials, handling dropouts, survival analysis, robust data analysis, cate

NMR in Pharmaceutical Science

Author : Jeremy R. Everett
Publisher : John Wiley & Sons
ISBN 13 : 1118660250
Total Pages : 506 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis NMR in Pharmaceutical Science by : Jeremy R. Everett

Download or read book NMR in Pharmaceutical Science written by Jeremy R. Everett and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes

Sterile Product Development

Author : Parag Kolhe
Publisher : Springer Science & Business Media
ISBN 13 : 1461479789
Total Pages : 590 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Sterile Product Development by : Parag Kolhe

Download or read book Sterile Product Development written by Parag Kolhe and published by Springer Science & Business Media. This book was released on 2013-10-12 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book: • Formulation approaches that discuss a variety of dosage forms including protein therapeutics, lipid-based controlled delivery systems, PEGylated biotherapeutics, nasal dosage form, and vaccines • Process, container closure and delivery considerations including freeze-thaw process challenges, best practices for technology transfer to enable commercial product development, innovations and advancement in aseptic fill-finish operations, approaches to manufacturing lyophilized parenteral products, pen / auto-injector delivery devices, and associated container closure integrity testing hurdles for sterile product closures • Regulatory and quality aspects in the areas of particulate matter and appearance evaluation, sterile filtration, admixture compatibility considerations, sterilization process considerations, microbial contamination investigations and validation of rapid microbiological methods, and dry and moist heat sterilizers This book is a useful resource to scientists and researchers in both industry and academia, and it gives process and product development engineers insight into current industry practices and evolving regulatory expectations for sterile product development.

Pharmaceutical Industry Practices on Genotoxic Impurities

Author : Heewon Lee
Publisher : CRC Press
ISBN 13 : 1439874212
Total Pages : 536 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Pharmaceutical Industry Practices on Genotoxic Impurities by : Heewon Lee

Download or read book Pharmaceutical Industry Practices on Genotoxic Impurities written by Heewon Lee and published by CRC Press. This book was released on 2014-08-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, methods, interpretati

Drug Delivery to the Brain

Author : Margareta Hammarlund-Udenaes
Publisher : Springer Science & Business Media
ISBN 13 : 1461491053
Total Pages : 737 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Drug Delivery to the Brain by : Margareta Hammarlund-Udenaes

Download or read book Drug Delivery to the Brain written by Margareta Hammarlund-Udenaes and published by Springer Science & Business Media. This book was released on 2013-12-03 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Applied Pharmacometrics

Author : Stephan Schmidt
Publisher : Springer
ISBN 13 : 1493913042
Total Pages : 570 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Applied Pharmacometrics by : Stephan Schmidt

Download or read book Applied Pharmacometrics written by Stephan Schmidt and published by Springer. This book was released on 2014-12-01 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book presents numerous examples of specific applications that utilize pharmacometrics with modeling and simulations over a variety of therapeutic areas, including pediatrics, diabetes, obesity, infections, psychiatrics, Alzheimer’s disease, and dermatology, among others. The examples illustrate how results from all phases of drug development can be integrated in a more timely and cost-effective process. Applying pharmacometric decision tools during drug development can allow objective, data-based decision making. At the same time, the process can identify redundant or unnecessary experiments as well as some costly clinical trials that can be avoided. In addition to cost saving by expedited development of successful drug candidates, pharmacometrics has an important economic impact in drug product selection. Unsuccessful drug candidates can be identified early and discontinued without expending efforts required for additional studies and allocating limited resources. Hence, pharmacometric modeling and simulation has become a powerful tool to bring new and better medications to the patient at a faster pace and with greater probability of success.

Statistical Design and Analysis in Pharmaceutical Science

Author : Shein-Chung Chow
Publisher : CRC Press
ISBN 13 : 1482273136
Total Pages : 581 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Statistical Design and Analysis in Pharmaceutical Science by : Shein-Chung Chow

Download or read book Statistical Design and Analysis in Pharmaceutical Science written by Shein-Chung Chow and published by CRC Press. This book was released on 2018-10-03 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Offers a comprehensive, unified presentation of statistical designs and methods of analysis for all stages of pharmaceutical development--emphasizing biopharmaceutical applications and demonstrating statistical techniques with real-world examples."

Autonomic Pharmacology

Author : Kenneth J Broadley
Publisher : CRC Press
ISBN 13 : 1135741387
Total Pages : 630 pages
Book Rating : 4.1/5 (357 download)

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Book Synopsis Autonomic Pharmacology by : Kenneth J Broadley

Download or read book Autonomic Pharmacology written by Kenneth J Broadley and published by CRC Press. This book was released on 2017-12-14 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This overview of autonomic pharmacology describes the anatomy, physiology and pharmacology of the autonomic involuntary nervous system. Covering the diverse group of drugs acting on the autonomous nervous system, their actions are reviewed together with their clinical uses, side effects, interactions and subcellular mechanisms of action. Information is organized in a logical flow, bringing together the latest advances in an integrated form on topics usually found only in a fragmented form.; This work is intended for all those researching in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry and molecular biology.

Modern Pharmaceutics

Author : Gilbert S. Banker
Publisher :
ISBN 13 :
Total Pages : 848 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Modern Pharmaceutics by : Gilbert S. Banker

Download or read book Modern Pharmaceutics written by Gilbert S. Banker and published by . This book was released on 1979 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceutical and Clinical Calculations

Author : Mansoor A. Kahn
Publisher : CRC Press
ISBN 13 : 142001479X
Total Pages : 411 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Pharmaceutical and Clinical Calculations by : Mansoor A. Kahn

Download or read book Pharmaceutical and Clinical Calculations written by Mansoor A. Kahn and published by CRC Press. This book was released on 2000-04-06 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical and clinical calculations are critical to the delivery of safe, effective, and competent patient care and professional practice. Pharmaceutical and Clinical Calculations, Second Edition addresses this crucial component, while emphasizing contemporary pharmacy practices. Presenting the information in a well-organized and easy-to-under

Pharmaceutical Production Facilities: Design and Applications

Author : Basant Puri
Publisher : CRC Press
ISBN 13 : 113574355X
Total Pages : 344 pages
Book Rating : 4.1/5 (357 download)

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Book Synopsis Pharmaceutical Production Facilities: Design and Applications by : Basant Puri

Download or read book Pharmaceutical Production Facilities: Design and Applications written by Basant Puri and published by CRC Press. This book was released on 1998-02-11 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufac

Cytotoxins and Immunotoxins for Cancer Therapy

Author : Koji Kawakami
Publisher : CRC Press
ISBN 13 : 0203303164
Total Pages : 242 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Cytotoxins and Immunotoxins for Cancer Therapy by : Koji Kawakami

Download or read book Cytotoxins and Immunotoxins for Cancer Therapy written by Koji Kawakami and published by CRC Press. This book was released on 2004-11-15 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource. For the first time,

Essential Statistics for the Pharmaceutical Sciences

Author : Philip Rowe
Publisher : John Wiley & Sons
ISBN 13 : 1118913418
Total Pages : 431 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Essential Statistics for the Pharmaceutical Sciences by : Philip Rowe

Download or read book Essential Statistics for the Pharmaceutical Sciences written by Philip Rowe and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody from undergraduate project students to experienced researchers should find the material they need. This book will guide all those who are not specialist statisticians in using sound statistical principles throughout the whole journey of a research project - designing the work, selecting appropriate statistical methodology and correctly interpreting the results. It deliberately avoids detailed calculation methodology. Its key features are friendliness and clarity. All methods are illustrated with realistic examples from within pharmaceutical science. This edition now includes expanded coverage of some of the topics included in the first edition and adds some new topics relevant to pharmaceutical research. a clear, accessible introduction to the key statistical techniques used within the pharmaceutical sciences all examples set in relevant pharmaceutical contexts. key points emphasised in summary boxes and warnings of potential abuses in ‘pirate boxes’. supplementary material - full data sets and detailed instructions for carrying out analyses using packages such as SPSS or Minitab – provided at: https://www.wiley.com/go/rowe/statspharmascience2e An invaluable introduction to statistics for any science student and an essential text for all those involved in pharmaceutical research at whatever level.