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Author :
Publisher : Paul Scherrer Institut
ISBN 13 : 9783952140901
Total Pages : 100 pages
Book Rating : 4.1/5 (49 download)
Download or read book PET Pharmacokinetic Course written by and published by Paul Scherrer Institut. This book was released on 1997-01-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fabian Kiessling
Publisher : Springer
ISBN 13 : 3319422022
Total Pages : 875 pages
Book Rating : 4.3/5 (194 download)
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer. This book was released on 2017-05-22 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Author : Peter G. Welling
Publisher : Springer Science & Business Media
ISBN 13 : 3642786804
Total Pages : 546 pages
Book Rating : 4.6/5 (427 download)
Download or read book Pharmacokinetics of Drugs written by Peter G. Welling and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of researchers' experience in the areas of bioanalysis, pharmacokinetics, and drug metabolism, to present an up-to-date and comprehensive treatise on the application of these and related technologies in drug discovery, development, and clinical use. Contents cover descriptions of analytical methods, in vitro metabolism technology and membrane transport, reappraisal of classical pharmacokinetic problems, and the time course of drug action. The book concludes with a description of PET and imaging methods in pharmacokinetics and an appendix containing a critical appraisal of computer methods and pharmacokinetic software available for PCs.
Author : Aldo Rescigno
Publisher : Springer Science & Business Media
ISBN 13 : 1468480537
Total Pages : 434 pages
Book Rating : 4.4/5 (684 download)
Download or read book New Trends in Pharmacokinetics written by Aldo Rescigno and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade or so has witnessed tremendous progress in methodology in the field of drug development in general and pharmacokinetics in particular. Clinical pharmacokinetics is using new tools for probing into the "black box" once being ac cessible only partly through experimental techniques and, mostly through mathemati cal and computer means. Development of computerized scanning, positron emission tomography (PET), stereoselectivity and other techniques are now enabling investi gators to have better pictures of the systems they are studying. Mathematical models through computer simulation and statistical estimation, mostly due to easy access be cause of inexpensive yet powerful personal computers, are enabling us to investigate ultrastructures and their functional connectivity in more detail. As a consequence, new hypotheses are being formed and tested in various related fields. In clinical pharmacokinetics, mostly due to mathematical modeling, more accurate interspecies scaling of pharmacokinetic parameters and dosimetry can be done now-a-days. The concept of "a human is a bigger rat" does not necessarily fly as a consequence. Pharmacokinetic concepts are becoming powerful tools in meaningful carcinogenic and toxic risk extrapolation of different chemicals in humans. New dose delivery designs are being formulated using pharmacokinetic techniques for different pharmaceutical compounds. Investigations continue in the academia, research institutions, pharmaceutical, biotechnological, and agricultural industries in developmental and physiological aspects of different chemicals for the benefit of mankind. The idea of a school on "New Trends in Pharmacokinetics", from which the present pUblication was made possible, took shape over almost a year.
Author :
Publisher : Academic Press
ISBN 13 : 0123973163
Total Pages : 2668 pages
Book Rating : 4.1/5 (239 download)
Download or read book Brain Mapping written by and published by Academic Press. This book was released on 2015-02-14 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed
Author : Yves Lemoigne
Publisher : Springer Science & Business Media
ISBN 13 : 1402087527
Total Pages : 296 pages
Book Rating : 4.4/5 (2 download)
Download or read book Molecular Imaging: Computer Reconstruction and Practice written by Yves Lemoigne and published by Springer Science & Business Media. This book was released on 2008-09-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports the majority of lectures given during the NATO Advanced Study Institute ASI-982440, which was held at the European Scienti?c Institute of Archamps (ESI, Archamps – France) from November 9 to November 21, 2006. The ASI course was structured in two parts, the ?rst was dedicated to individual imaging techniques while the second is the object of this volume and focused on data modelling and processing and on image archiving and distribution. Courses devoted to nuclear medicine and digital imaging techniques are collected in a c- plementary volume of NATO Science Series entitled “Physics for Medical Imaging Applications” (ISBN 978-1-4020-5650-5). Every year in autumn ESI organises the European School of Medical Physics, which covers a large spectrum of topics ranging from Medical Imaging to Rad- therapy, over a period of ?ve weeks. Thanks to the Cooperative Science and Te- nology sub-programme of the NATO Science Division, weeks two and three were replaced this year by the ASI course dedicated to “Molecular Imaging from Physical Principles to Computer Reconstruction and Practice”. This allowed the participation ofexpertsandstudentsfrom20differentcountries,withdiverseculturalbackground and professional experience (Africa, America, Asia, and Europe). A further positive outcome of NATO ASI participation is the publication of this book, which contains the lectures series contributed by speakers during the second week of the ASI.
Author : Bruno P. Guiard
Publisher : Bentham Science Publishers
ISBN 13 : 1608054675
Total Pages : 300 pages
Book Rating : 4.6/5 (8 download)
Download or read book Neurobiology of Mood Disorders written by Bruno P. Guiard and published by Bentham Science Publishers. This book was released on 2014-02-27 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.
Author : Philip H. Elsinga
Publisher : World Scientific
ISBN 13 : 981431773X
Total Pages : 799 pages
Book Rating : 4.8/5 (143 download)
Download or read book Trends on the Role of PET in Drug Development written by Philip H. Elsinga and published by World Scientific. This book was released on 2012 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug development is very expensive and a fight against time. PET offers possibilities to speed up this process by adding unique in vivo information on pharmacokinetics/dynamics of a drug at an early stage. This information can help decision makers to move the drug in the drug development process or to decide to stop further developments. This unique and complete book highlights the different ways PET can be used and describes the latest trends in the various disciplines within nuclear medicine to further improve methodologies and increase the number of tools to accelerate drug development. Various topics within tracer development, instrumentation, data analysis and many clinical and preclinical topics are described by leading scientists from industry and academia.
Author : Magdy Khalil
Publisher : Springer Science & Business Media
ISBN 13 : 3540859624
Total Pages : 420 pages
Book Rating : 4.5/5 (48 download)
Download or read book Basic Sciences of Nuclear Medicine written by Magdy Khalil and published by Springer Science & Business Media. This book was released on 2010-10-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.
Author : Jill E. Maddison
Publisher : Bailliere Tindall
ISBN 13 : 9780702025730
Total Pages : 575 pages
Book Rating : 4.0/5 (257 download)
Download or read book Small Animal Clinical Pharmacology written by Jill E. Maddison and published by Bailliere Tindall. This book was released on 2002-01 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, clinically oriented reference provides the veterinarian with all the relevant clinical pharmacology information needed when selecting drug regimes for pets. It compiles easy-to-find data on dosages, routes of administration, formulation, metabolism, side effects, interactions, special considerations, and more, all in one convenient volume. Information on each drug class is presented in a consistent format, making it easy to locate key information. Chapters on all the main drug classes are complemented by additional chapters on key body systems, as well as introductory chapters on pharmacokinetics and pharmacological principles.
Author : Bruce A. Chabner
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496375157
Total Pages : 640 pages
Book Rating : 4.4/5 (963 download)
Download or read book Cancer Chemotherapy, Immunotherapy and Biotherapy written by Bruce A. Chabner and published by Lippincott Williams & Wilkins. This book was released on 2018-09-06 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Thoroughly revised and reformatted, the sixth edition of Cancer Chemotherapy, Immunotherapy and Biotherapy reflects recent significant changes in cancer treatment. This newly streamlined edition contains full-color illustrations, more tables for quick reference, and new immunotherapy and molecular targeted therapy content that brings you fully up to date with the state of the art in all current cancer therapies.
Author : Anthony F. Shields
Publisher : Springer Science & Business Media
ISBN 13 : 1597453412
Total Pages : 343 pages
Book Rating : 4.5/5 (974 download)
Download or read book In Vivo Imaging of Cancer Therapy written by Anthony F. Shields and published by Springer Science & Business Media. This book was released on 2007-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: A variety of cutting-edge imaging techniques, including their use for best practice, are addressed in this book. The book also provides examples of results found in both pre-clinical and clinical studies. This comprehensive text covers the entire spectrum of in vivo imaging for oncology. It will aide clinicians at all levels in keeping up with the most cutting-edge techniques.
Author : Jill E. Maddison
Publisher : Elsevier Health Sciences
ISBN 13 : 0702028584
Total Pages : 600 pages
Book Rating : 4.7/5 (2 download)
Download or read book Small Animal Clinical Pharmacology written by Jill E. Maddison and published by Elsevier Health Sciences. This book was released on 2008 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text
Author : Bruce A. Chabner
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1605474312
Total Pages : 836 pages
Book Rating : 4.6/5 (54 download)
Download or read book Cancer Chemotherapy and Biotherapy written by Bruce A. Chabner and published by Lippincott Williams & Wilkins. This book was released on 2010-11-08 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.
Author : Eric T. Ahrens
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121531706
Total Pages : 310 pages
Book Rating : 4.5/5 (317 download)
Download or read book In Vivo Cellular and Molecular Imaging written by Eric T. Ahrens and published by Gulf Professional Publishing. This book was released on 2005-11-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent times there has been an explosive expansion of new imaging methodologies that are capable of visualizing specific populations of cells and molecular events in vivo. Vital imaging enhances our ability to study animal models of human development and disease, such as cancers, cardiovascular disease, diabetes, and Alzheimer's. Furthermore, non-invasive imaging may ultimately be useful for monitoring new generations of clinical molecular and cellular therapeutics, such as those utilizing viral vectors and stem cells. These new capabilities have been facilitated by the development of new imaging probes or reagents that target specific cell types, are chemically responsive to physiology, or are responsive to the presence of specific molecules, such as nucleic acids or enzymes. This volume provides an introduction to some of the most exciting methods and applications of emerging non-invasive imaging technologies using magnetic resonance imaging (MRI), positron emission tomography (PET), and various biophotonic approaches. Highlighted, are recent developments in reagent design that impart unique abilities to these imaging modalities to elucidate biological processes in vivo. * Includes 9 chapters by expert researchers in the field of imaging * Introduces new methods and applications of non-invasive imaging technologies * Covers ermerging topics in imaging such as in vivo cell cancer cells, imaging of autoimmune diseases, and maganetic resonance imaging
Author : Todd E. Barnhart
Publisher :
ISBN 13 :
Total Pages : 278 pages
Book Rating : 4.:/5 (89 download)
Download or read book Radiotracer Methodology with Applications to Functional PET/TMS written by Todd E. Barnhart and published by . This book was released on 2004 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128144262
Total Pages : 754 pages
Book Rating : 4.1/5 (281 download)
Download or read book Biopharmaceutics and Pharmacokinetics Considerations written by and published by Academic Press. This book was released on 2021-07-07 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology
