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Pesticide And Xenobiotic Metabolism In Aquatic Organisms
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Book Synopsis Intentional Human Dosing Studies for EPA Regulatory Purposes by : National Research Council
Download or read book Intentional Human Dosing Studies for EPA Regulatory Purposes written by National Research Council and published by National Academies Press. This book was released on 2004-06-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.
Download or read book Reactions and Processes written by and published by Springer. This book was released on 1980-09-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary discipline, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environmental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environ ment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems.
Book Synopsis Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe by : Lubomir I. Simeonov
Download or read book Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe written by Lubomir I. Simeonov and published by Springer. This book was released on 2014-07-08 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work is a fine contribution to the broad field of environmental security in the context of risk assessment and management of obsolete pesticides for the region of Southeast Europe. The purpose of this book is to evaluate the existing knowledge of improper disposal of obsolete pesticides in the region, to estimate the associated impact on environmental health, and to develop recommendations to mitigate or eliminate threats posed to the environment, biodiversity and human life. The issues discussed in the book include: reviews of the transport and fate of pesticides and associated contaminated materials in different environmental media and identification of the principal sources, emission routes and patterns of environmental pollution with pesticides; a recognition of the most suitable methods for environmental sampling analysis and sample preparation; an evaluation of the current methods and techniques for chemical and mass analysis of environmental and biological samples and discussion of the metrological and quality aspects of trace analyses; a characterization of the environmental and human health impacts of pesticide pollution, the health effects associated with acute and chronic exposure and the use of epidemiological data for risk assessment; a revision of the existing chemical safety regulations and strategies for protection and management of obsolete pesticide stocks; a survey of the international conventions, directives and standards concerning pesticide use.
Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council
Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.
Book Synopsis Xenobiotics in Aquatic Animals by : Mohd Ashraf Rather
Download or read book Xenobiotics in Aquatic Animals written by Mohd Ashraf Rather and published by Springer Nature. This book was released on 2023-05-10 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the latest understanding of the impact of xenobiotics on the developmental and reproductive processes of aquatic animals, particularly nektonic forms, which comprise an important group of aquatic ecosystems. Aquaculture is quickly becoming the largest contributor of fish protein for human consumption. As the aquaculture business expands, farmed fish will be exposed to more environmental toxins, necessitating the use of chemical therapeutic drugs for fish. This book brings together experts on the regulation of environmental toxins and food chemicals from around the world, as well as researchers looking into the metabolism and disposal of foreign chemicals (xenobiotics) in fish species. The impact of xenobiotics on reproductive and developmental biology of all living forms has become of prime importance at the current time. As the effect of these xenobiotics on aquatic animals is an emerging area for research and development, several groups across the world are working on these aspects, targeting different groups of fishes in both marine and freshwater ecosystems. This collective work highlights several key and updated recent aspects of different types of xenobiotics entering aquatic ecosystems, impacts of these agents on reproductive physiology, developmental biology, breeding biology, hormonal imbalance, aquatic ecology, and pollution on the aquatic ecosystem. The unique aggregation of different types of stressors to aquatic animals under a single volume will be a useful reference for readers, including scientists, teachers, students, researchers and policymakers and those involved in aquaculture and environment conservation.
Book Synopsis Aquatic Pollutants by : O. Hutzinger
Download or read book Aquatic Pollutants written by O. Hutzinger and published by Elsevier. This book was released on 2015-12-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquatic Pollutants: Transformation and Biological Effects contains the proceedings of the Second International Symposium on Aquatic Pollutants held at Noordwijkerhout (Amsterdam), The Netherlands on September 26-28, 1977. Organized into 47 chapters, this book first describes the aquatic pollutants and their potential biological effects. Subsequent chapters elucidate chemicals with pollution potential; multidetection approach to analysis of organic pollutants in water; volatilization of pollutants from water; microbial transformations of aromatic pollutants; and photochemical transformation of pollutants in water. Other chapters address oxidation of organic compounds in aquatic systems; laboratory microcosms for use in determining pollutant stress; continuous biomonitoring systems for detection of toxic levels of water pollutants; and health aspects of water recycling practices. This book will be useful as a review of existing knowledge in this field. It will also stimulate further thought and research.
Book Synopsis Pesticide Biotransformation and Disposition by : Ernest Hodgson
Download or read book Pesticide Biotransformation and Disposition written by Ernest Hodgson and published by Academic Press. This book was released on 2012-01-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotransformation of Pesticides is an updated, "one-stop" resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. - Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment - Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides - Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations
Book Synopsis Pesticides in Crop Production by : Prabhat Kumar Srivastava
Download or read book Pesticides in Crop Production written by Prabhat Kumar Srivastava and published by John Wiley & Sons. This book was released on 2020-04-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the diversity of pesticides used in modern agricultural practices, and the relevant social and environmental issues Pesticides in Crop Production offers an important resource that explores pesticide action in plants; pesticide metabolism in soil microbes, plants and animals; bioaccumulation of pesticides and sensitiveness of microbiome towards pesticides. The authors explore pesticide risk assessment, the development of pesticide resistance in pests, microbial remediation of pesticide intoxicated legumes and pesticide toxicity amelioration in plants by plant hormones. The authors include information on eco-friendly pest management. They review the impact of pesticides on soil microorganism, crops and other plants along with the impact on other organisms like aquatic fauna and terrestrial animals including human beings. The book also contains an analysis of pesticide by GC-MS/MS (Gas Chromatography tandem Mass Spectrometry) a reliable method for the quantification and confirmation of multiclass pesticide residues. This important book: Offers a comprehensive guide to the use of the diversity of pesticides and the pertinent social and environmental issues Explores the impact of pesticides from morphological, anatomical, physiological and biochemical perspectives Shows how pesticides affects soil microorganisms, crops and other plants along with the impact on other organisms like aquatic fauna and animals Critically examines whether chemical pesticides are boon or bane and whether they can be replaced by environmental friendly pesticides Written for students, researchers and professionals in agriculture, botany, entomology and biotechnology, Pesticides in Crop Production examines the effects of chemical pesticides and the feasibility of using bio-pesticides.
Book Synopsis Pesticide and Xenobiotic Metabolism in Aquatic Organisms by : Mohammed Abdul Quddus Khan
Download or read book Pesticide and Xenobiotic Metabolism in Aquatic Organisms written by Mohammed Abdul Quddus Khan and published by . This book was released on 1979 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Xenobiotics in Fish written by D.J. Smith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation of environmental contaminants and food chemicals and researchers investigating the metabolism and disposition of foreign chemicals (xenobiotics) in fish species.
Book Synopsis Fish Ecotoxicology by : Thomas Braunbeck
Download or read book Fish Ecotoxicology written by Thomas Braunbeck and published by Springer Science & Business Media. This book was released on 1998 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: In modern ecotoxicology, fish have become the major vertebrate model, and a tremendous body of information has been accumulated. This volume attempts to summarize our present knowledge in several fields of primary ecotoxicological interest ranging from the use of (ultra)structural modifications of selected cell systems as sources of biomarkers for environmental impact over novel approaches to monitoring the impact of xenobiotics with fish in vitro systems such as primary and permanent fish cell cultures, the importance of early life-stage tests with fish, the bioaccumulation of xenobiotics in fish, the origin of liver neoplastic lesions in small fish species, immunocytochemical approaches to monitoring effects in cytochrome P450-related biotransformation, the impact of heavy metals in soft water systems, the environmental toxicology of organotin compounds, oxidative stress in fish by environmental pollutants to effects by estrogenic substances in aquatic systems.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :World Health Organization ISBN 13 :9789283201502 Total Pages :0 pages Book Rating :4.2/5 (15 download)
Book Synopsis Some Organophosphate Insecticides and Herbicides by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Some Organophosphate Insecticides and Herbicides written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.
Book Synopsis Xenobiotics in the Soil Environment by : Muhammad Zaffar Hashmi
Download or read book Xenobiotics in the Soil Environment written by Muhammad Zaffar Hashmi and published by Springer. This book was released on 2017-02-15 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the vast variety of xenobiotics, such as pesticides, antibiotics, antibiotic resistance genes, agrochemicals and other pollutants, their interactions with the soil environment, and the currently available strategies and techniques for soil decontamination and bioremediation. Topics covered include: transport mechanisms of pollutants along the Himalayas; use of earthworms in biomonitoring; metagenomic strategies for assessing contaminated sites; xenobiotics in the food chain; phyto-chemical remediation; biodegradation by fungi; and the use of enzymes and potential microbes in biotransformation. Accordingly, the book offers a valuable guide for scientists in the fields of environmental ecology, soil and food sciences, agriculture, and applied microbiology.
Book Synopsis Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States by : John P. Giesy
Download or read book Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States written by John P. Giesy and published by Springer Science & Business Media. This book was released on 2014-04-10 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Book Synopsis Hazardous Chemicals in Fish by : John J. Lech
Download or read book Hazardous Chemicals in Fish written by John J. Lech and published by . This book was released on 1984 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Reviews of Environmental Contamination and Toxicology by : George W. Ware
Download or read book Reviews of Environmental Contamination and Toxicology written by George W. Ware and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences.
Book Synopsis Bioaccumulation Testing and Interpretation for the Purpose of Sediment Quality Assessment by :
Download or read book Bioaccumulation Testing and Interpretation for the Purpose of Sediment Quality Assessment written by and published by . This book was released on 2000 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
