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Perspectives In Inflammation
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Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Book Synopsis Perspectives in Inflammation by : D.A. Willoughby
Download or read book Perspectives in Inflammation written by D.A. Willoughby and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report on Future Trends in Inflammation III is the record of what is now firmly established as a series of multidisciplinary meetings organized by the European Biological Research Association. The aim of these meetings is to provide a forum for free exchange of information between basic scien tists of many disciplines and clinicians to provide better understanding of problems of common interest. The next major meeting wi1l be held in 1980.* The European Biological Research Association promotes scientific and clinical collaboration among the member countries ofthe EEe. It encourages exchange of information between scientists and clinicians from centres all over the world. In addition to the major international meetings small work shops are organized on specific problems of common interest. Once again the Editors have attempted to capture the spirit of the meeting by publishing 'verbatim' the discussion. It can be seen that the discussions were exciting and formed an important part of the meeting. It is possible that inaccuracies have crept into the discussions; if so we apologize. It was decided that the proceedings of such a meeting had maximum value with rapid publication. We would like to thank the participants for the enthusiasm and goodwill which persisted throughout the meeting both scientifically and socially. Above all we wish to thank H.R.H. The Duchess of Kent for acting as Patron of this meeting.
Book Synopsis Perspectives in Inflammation by : D. A. Willoughby
Download or read book Perspectives in Inflammation written by D. A. Willoughby and published by . This book was released on 1977 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Perspectives in inflammation by : J. P. Giroud
Download or read book Perspectives in inflammation written by J. P. Giroud and published by . This book was released on 1977 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon
Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.
Book Synopsis Fundamentals of Inflammation by : Charles N. Serhan
Download or read book Fundamentals of Inflammation written by Charles N. Serhan and published by Cambridge University Press. This book was released on 2010-04-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.
Book Synopsis Physiology of Inflammation by : Klaus Ley
Download or read book Physiology of Inflammation written by Klaus Ley and published by Springer. This book was released on 2013-05-27 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the physiological processes relevant to inflammation. It centers on the recruitment of leukocytes to sites of injury and infection, their function in the tissue and the eventual resolution of inflammation.
Book Synopsis Immunity and Inflammation in Health and Disease by : Shampa Chatterjee
Download or read book Immunity and Inflammation in Health and Disease written by Shampa Chatterjee and published by Academic Press. This book was released on 2017-08-31 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption
Book Synopsis Inflammation Research Perspectives by : Giocomo T. Romano
Download or read book Inflammation Research Perspectives written by Giocomo T. Romano and published by Nova Science Pub Incorporated. This book was released on 2008-01-01 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. Inflammation is not a synonym for infection. Even in cases where inflammation is caused by infection it is incorrect to use the terms as synonyms: infection is caused by an exogenous pathogen, while inflammation is the response of the organism to the pathogen. In the absence of inflammation, wounds and infections would never heal and progressive destruction of the tissue would compromise the survival of the organism. However, inflammation which runs unchecked can also lead to a host of diseases, such as hay fever, atheriosclerosis, and rheumatoid arthritis. It is for this reason that inflammation is normally tightly regulated by the body. Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process. This new book presents leading-edge research from around the world.
Book Synopsis Inflammatory Diseases by : Mahin Khatami
Download or read book Inflammatory Diseases written by Mahin Khatami and published by BoD – Books on Demand. This book was released on 2012-02-10 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of comprehensive reviews contributed by experts in the diverse fields of acute and chronic inflammatory diseases, with emphasis on current pharmacological and diagnostic options. Interested professionals are also encouraged to review the contributions made by experts in a second related book entitled "Inflammation, Chronic Diseases and Cancer"; it deals with immunobiology, clinical reviews, and perspectives of the mechanisms of immune inflammatory responses that are involved in alterations of immune dynamics during the genesis, progression and manifestation of a number of inflammatory diseases and cancers, as well as perspectives for diagnosis, and treatment or prevention of these disabling and potentially preventable diseases, particularly for the growing population of older adults around the globe.
Book Synopsis Perspectives in Inflammation Biology by : Ena Ray Banerjee
Download or read book Perspectives in Inflammation Biology written by Ena Ray Banerjee and published by Springer Science & Business Media. This book was released on 2013-10-16 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Perspectives in Inflammation Biology” outlines detailed studies using preclinical murine models in Inflammation. The book is meant for academicians, industry persons, research scholars and students alike. The detailed perspective for a beginner and the exhaustive methodologies and analyses outlined, for the veteran researcher, makes this book a unique link between someone who is thinking of embarking on a study of inflammation and one who is delving deep into this area of specialization. The book deals with asthma and allergy as specific disease areas of inflammation of the lung, aseptic peritonitis as a disease of systemic inflammation and details how each role player in its pathophysiology has a unique niche of activity. Data acquisition, sequentiality and analyses in context demonstrate how each role player is validated systematically to become a target for drug discovery. Methods and models used in the course of my work and their relevance will demonstrate to the researcher how a study can be developed from an idea. Further into a researcher’s ongoing work, this book is meant to stimulate new questions and pave ways for better dissection of a phenomenon. The highlights of this book are the detailed tables tabulating sub species of immune cells, their inflammatory recruitment indices, their translation into tissue-to-tissue traffic of the inflammatory stimulus and the delicate interplay of resident structural cells, cells recruited from circulation, their feedback poiesis in bone marrow, their instruction in the lymphoid organs and tissues as well as the non-cellular mediators synthesized from corresponding genetic instruction. The book shall definitely help students and researchers how a disease can be simplified from its complex ramifications and network of implications and put back into perspective and the whole thing falls into place without an intimate understanding of the mechanism and the compelling circumstances that causes a disease, a drug hunter cannot hope to begin her quest. To find the “Achilles’ heel” and effectively neutralize the enemy!
Book Synopsis Recent Developments in Anti-Inflammatory Therapy by : Parteek Prasher
Download or read book Recent Developments in Anti-Inflammatory Therapy written by Parteek Prasher and published by Academic Press. This book was released on 2023-02-17 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry
Book Synopsis Perspectives in Inflammation by : J. P. Giroud
Download or read book Perspectives in Inflammation written by J. P. Giroud and published by . This book was released on 1977 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Perspectives in Inflammation : Futuretrends and Developments : the Proceedings of the Third International Meeting on Future Trends in Inflammation, Organized by the European Biological Research Association and Heldin London, February 14th-18th, 1977 by : International meeting on future trends in inflammation, 3rd (london, 1977. w)
Download or read book Perspectives in Inflammation : Futuretrends and Developments : the Proceedings of the Third International Meeting on Future Trends in Inflammation, Organized by the European Biological Research Association and Heldin London, February 14th-18th, 1977 written by International meeting on future trends in inflammation, 3rd (london, 1977. w) and published by . This book was released on 1977 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inflammation and Natural Products by : Sreeraj Gopi
Download or read book Inflammation and Natural Products written by Sreeraj Gopi and published by Academic Press. This book was released on 2021-01-19 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.446 pages Approx.446 pages
Book Synopsis Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics by : Jordi Camps
Download or read book Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics written by Jordi Camps and published by Springer. This book was released on 2014-07-19 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation underpin most diseases; their mechanisms are inextricably linked. For example, chronic inflammation is associated with oxidation, anti-inflammatory cascades are linked to decreased oxidation, increased oxidative stress triggers inflammation and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress and inflammation represent the causes or the consequences of cellular pathology, they contribute significantly to the pathogenesis of non-communicable diseases. The incidence of obesity and other related metabolic disturbances are rising, as are age-related diseases due to progressively aging populations. Interrelations between the mechanisms of oxidative stress and of inflammatory signaling and metabolism are, in the broad sense of energy transformation, being increasingly recognized as part of the problem in non-communicable diseases. The book Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and Perspectives in Therapeutics is an update on the latest research on the molecular basis of non-communicable diseases and the search for possible therapeutic alternatives. The authors of this monograph are experts in their field and the book as a whole, provides an overview of the biochemical alterations underlying diseases such as cardiovascular disease, cancer, obesity, renal disease, neurological diseases and diabetes, emphasizing those aspects that they share in common. We hope that this book will be useful for researchers in biomedicine and also for physicians interested in finding the root causes of the disease, as well as for post-graduate students in biochemistry, molecular biology, nutrition or medicine.
Book Synopsis Perspectives in Inflammation by : European Biological Research Association
Download or read book Perspectives in Inflammation written by European Biological Research Association and published by . This book was released on 1977 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:
