Personalized Treatment Of Breast Cancer

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Personalized Treatment of Breast Cancer

Author : Masakazu Toi
Publisher : Springer
ISBN 13 : 4431555528
Total Pages : 381 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Personalized Treatment of Breast Cancer by : Masakazu Toi

Download or read book Personalized Treatment of Breast Cancer written by Masakazu Toi and published by Springer. This book was released on 2016-05-24 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.

Breast Cancer: From Bench to Personalized Medicine

Author : Saima Shakil Malik
Publisher : Springer Nature
ISBN 13 : 981190197X
Total Pages : 534 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Breast Cancer: From Bench to Personalized Medicine by : Saima Shakil Malik

Download or read book Breast Cancer: From Bench to Personalized Medicine written by Saima Shakil Malik and published by Springer Nature. This book was released on 2022-05-14 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.

Economic Dimensions of Personalized and Precision Medicine

Author : Ernst R. Berndt
Publisher : University of Chicago Press
ISBN 13 : 022661123X
Total Pages : 361 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Economic Dimensions of Personalized and Precision Medicine by : Ernst R. Berndt

Download or read book Economic Dimensions of Personalized and Precision Medicine written by Ernst R. Berndt and published by University of Chicago Press. This book was released on 2019-04-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Personalized Medicine in Oncology

Author : Ari VanderWalde
Publisher :
ISBN 13 : 9783036528205
Total Pages : 174 pages
Book Rating : 4.5/5 (282 download)

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Book Synopsis Personalized Medicine in Oncology by : Ari VanderWalde

Download or read book Personalized Medicine in Oncology written by Ari VanderWalde and published by . This book was released on 2022 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowhere is the explosion in comprehensive genomic testing more evident than in oncology. Multiple consensus guidelines now recommend molecular testing as the standard of care for most metastatic tumors. To aid in the advancement of this rapidly changing field, we intend this Special Issue of JPM to focus on technical developments in the genomic profiling of cancer, detail promising somatic alterations that either are, or have a high likelihood of being, relevant in the near future, and to address issues related to the pricing and value of these tests.The last few years have seen the cost of molecular testing decrease by orders of magnitude. In 2018, we saw the first “site-agnostic” drug approvals in cancer (for microsatellite unstable cancer (PD-1 inhibitors) and NTRK-fusions (TRK inhibitors)). Research on targetable mutations, determination of genetic “signatures” that can use multiple individual genes/pathways, development of targeted therapy, and insight into the value of new technology remains at the cutting edge of research in this field. We are soliciting papers that present new technologies to assess predictive biomarkers in cancer, original research (pre-clinical or clinical) that demonstrates promise for particular targeted therapies in cancer, and articles that explore the clinical and financial impacts of this paradigmatic shift in cancer diagnostics and treatment.

Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients

Author : Md Monzur Murshed
Publisher :
ISBN 13 :
Total Pages : 50 pages
Book Rating : 4.:/5 (119 download)

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Book Synopsis Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients by : Md Monzur Murshed

Download or read book Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients written by Md Monzur Murshed and published by . This book was released on 2019 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cytochrome P450 Family Members in the Personalized Treatment of Breast Cancer

Author : Hend Alrasheedi
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Cytochrome P450 Family Members in the Personalized Treatment of Breast Cancer by : Hend Alrasheedi

Download or read book Cytochrome P450 Family Members in the Personalized Treatment of Breast Cancer written by Hend Alrasheedi and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Breast Cancer Essentials

Author : Mahdi Rezai
Publisher : Springer Nature
ISBN 13 : 3030731472
Total Pages : 665 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Breast Cancer Essentials by : Mahdi Rezai

Download or read book Breast Cancer Essentials written by Mahdi Rezai and published by Springer Nature. This book was released on 2021-08-27 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is a disease requiring multidisciplinary management including surgery, medical and radiation oncology, radiology, pathology, nuclear medicine, genetic counseling, and psychological support. Each member of the team needs to be updated continuously on breast cancer treatment because of its rapidly changing nature. From the diagnostic procedures to operations and even in metastatic stages of breast cancer, surgeons play an essential part in multidisciplinary teams. After standard surgical options, oncoplastic breast surgery is rapidly becoming one of the most important surgical topics that should be learned by attending surgeons. The idea of writing this book stemmed from a collaboration between the European Academy of Senology (EAoS), European Institute of Oncology (IEO), Euro-Asian Society of Mastology (ESOMA), and SENATURK (Turkish Academy of Senology), which have been working together to promote better training in breast care for professionals. The book offers invaluable support for breast surgeons by covering critical and essential information in senology. It will also greatly benefit the other members of multidisciplinary teams, surgery residents, gynecologists, and plastic and reconstructive surgeons.

Precision Medicine in Cancer Therapy

Author : Daniel D. Von Hoff
Publisher : Springer
ISBN 13 : 3030163911
Total Pages : 283 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Precision Medicine in Cancer Therapy by : Daniel D. Von Hoff

Download or read book Precision Medicine in Cancer Therapy written by Daniel D. Von Hoff and published by Springer. This book was released on 2019-06-17 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Breast Cancer Research and Treatment

Author : Ouissam Al Jarroudi
Publisher : Springer Nature
ISBN 13 : 303133602X
Total Pages : 371 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Breast Cancer Research and Treatment by : Ouissam Al Jarroudi

Download or read book Breast Cancer Research and Treatment written by Ouissam Al Jarroudi and published by Springer Nature. This book was released on 2024-01-04 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters. Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management. The closing chapters deal with the challenges of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike.

Cancer Genetics and Genomics for Personalized Medicine

Author : Il-Jin Kim
Publisher : CRC Press
ISBN 13 : 1315341107
Total Pages : 230 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Cancer Genetics and Genomics for Personalized Medicine by : Il-Jin Kim

Download or read book Cancer Genetics and Genomics for Personalized Medicine written by Il-Jin Kim and published by CRC Press. This book was released on 2017-04-11 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine. The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are discussed as new diagnostic and prognostic markers for cancer. The avatar mouse model is also discussed for maximizing treatment efficacy and prognosis prediction, and so is microenvironment as a drug resistance mechanism. With classical and new pathological approaches, the book provides a systemic overview of personalized immunotherapies and hyperthermic intraperitoneal chemotherapy, followed by new emerging fields of hereditary cancer, thereby equipping readers to eventually contribute in developing more advanced tools and therapies for curing cancer.

Textbook of Personalized Medicine

Author : Kewal K. Jain
Publisher : Springer Nature
ISBN 13 : 3030620808
Total Pages : 744 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Springer Nature. This book was released on 2020-12-05 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.

Principles of Personalized Cancer Medicine

Author : Olen Hickey
Publisher : American Medical Publishers
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (874 download)

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Book Synopsis Principles of Personalized Cancer Medicine by : Olen Hickey

Download or read book Principles of Personalized Cancer Medicine written by Olen Hickey and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized cancer medicine studies human genes in different types of cancers. This field of medicine is helpful in designing more efficient treatments by utilising genetic information for developing different tests for cancer and the ways for preventing it. Standard cancer treatments are divided into four categories, which include chemotherapy, surgery, immunotherapy and radiation therapy. The patient's active participation is crucial to enhance the effectiveness of personalized medicines. It has fewer side effects than other forms of treatment, as it is designed to be more precise. A personalized treatment will not target the healthy cells and can have greater impact on cancer cells. Targeted therapy is one of the examples of personalized cancer medicine, which can be used to treat brain cancer, cervical cancer, breast cancer, liver cancer and pancreatic cancer. This book explores all the important principles of personalized cancer medicine. It presents researches and studies performed by experts across the globe. This book is appropriate for students seeking detailed information in this area of medicine as well as for experts.

Studies of Improving Therapeutic Outcomes of Breast Cancer Through Development of Personalized Treatments and Characterization of Gene Interactions

Download Studies of Improving Therapeutic Outcomes of Breast Cancer Through Development of Personalized Treatments and Characterization of Gene Interactions PDF Online Free

Author : Jing-Ru Jhan
Publisher :
ISBN 13 : 9781369422252
Total Pages : 184 pages
Book Rating : 4.4/5 (222 download)

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Book Synopsis Studies of Improving Therapeutic Outcomes of Breast Cancer Through Development of Personalized Treatments and Characterization of Gene Interactions by : Jing-Ru Jhan

Download or read book Studies of Improving Therapeutic Outcomes of Breast Cancer Through Development of Personalized Treatments and Characterization of Gene Interactions written by Jing-Ru Jhan and published by . This book was released on 2016 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management

Author : Aamir Ahmad
Publisher : Springer
ISBN 13 : 3319249320
Total Pages : 240 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management by : Aamir Ahmad

Download or read book Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management written by Aamir Ahmad and published by Springer. This book was released on 2015-12-24 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality.

Reimagining Women's Cancers

Author : Michele Berman
Publisher : Simon and Schuster
ISBN 13 : 0757319548
Total Pages : 360 pages
Book Rating : 4.7/5 (573 download)

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Book Synopsis Reimagining Women's Cancers by : Michele Berman

Download or read book Reimagining Women's Cancers written by Michele Berman and published by Simon and Schuster. This book was released on 2016-09-27 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: America's fascination with celebrities never gets old. From People magazine, with a readership of 43 million to Internet sites like JustJared.com with over 80 million monthly views, celebrity information not only sells, it educates people about important issues––including cancer. Information is empowering and reading about a famous person coping with cancer can not only be inspiring, it can save a life. That's what Reimagining Cancer exemplifies through each of the books in the series Cancer doesn't have to be a death sentence. About half of all cancers are preventable and can be avoided if current medical knowledge is better delivered*. This new series, beginning with Reimagining Women's Cancers—focusing on cancer of the breasts, ovaries, uterus, cervix, vagina and vulva—provides readers with that critical information to help them manage, cope, and recover through a concise, easy-to-read style and format. Beginning with a view of basic anatomy and an overview of how we view a particular cancer today, chapters flow easily into an explanation of signs, symptoms, diagnosis, scientific information and guidelines, and include a comprehensive survey of treatments and prevention. Woven throughout are stories, both medical and anecdotal, from women such as Angelina Jolie, Joan Lunden, Melissa Etheridge, Sandra Lee, Rita Wilson, Christina Applegate, and Suzanne Somers. Education is the key, and by using celebrity stories, Reimagining Women's Cancers can attract countless readers who might otherwise not pay attention to an epidemic that is likely to affect them or a loved one. * The recent World Cancer Report from the World Health Organization

Targeted Therapies in Breast Cancer

Author : Gw Sledge
Publisher : Clinical Pub
ISBN 13 : 9781846920660
Total Pages : 0 pages
Book Rating : 4.9/5 (26 download)

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Book Synopsis Targeted Therapies in Breast Cancer by : Gw Sledge

Download or read book Targeted Therapies in Breast Cancer written by Gw Sledge and published by Clinical Pub. This book was released on 2012-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.

Precision Medicine in Oncology

Author : Bulent Aydogan
Publisher : John Wiley & Sons
ISBN 13 : 1119432448
Total Pages : 288 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Precision Medicine in Oncology by : Bulent Aydogan

Download or read book Precision Medicine in Oncology written by Bulent Aydogan and published by John Wiley & Sons. This book was released on 2020-11-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A FRESH EXAMINATION OF PRECISION MEDICINE'S INCREASINGLY PROMINENT ROLE IN THE FIELD OF ONCOLOGY Precision medicine takes into account each patient's specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice. Precision Medicine in Oncology draws together the essential research driving the field forward, providing oncology clinicians and trainees alike with an illuminating overview of the technology and thinking behind the breakthroughs currently being made. Topics covered include: Biologically-guided radiation therapy Informatics for precision medicine Molecular imaging Biomarkers for treatment assessment Big data Nanoplatforms Casting a spotlight on this emerging knowledge base and its impact upon the management of tumors, Precision Medicine in Oncology opens up new possibilities and ways of working – not only for oncologists, but also for molecular biologists, radiologists, medical geneticists, and others.