Personalized Medicine As Innovation

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Economic Dimensions of Personalized and Precision Medicine

Author : Ernst R. Berndt
Publisher : University of Chicago Press
ISBN 13 : 022661106X
Total Pages : 361 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Economic Dimensions of Personalized and Precision Medicine by : Ernst R. Berndt

Download or read book Economic Dimensions of Personalized and Precision Medicine written by Ernst R. Berndt and published by University of Chicago Press. This book was released on 2019-04-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Advancing Healthcare Through Personalized Medicine

Author : Priya Hays
Publisher : Springer Nature
ISBN 13 : 3030801004
Total Pages : 755 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Advancing Healthcare Through Personalized Medicine by : Priya Hays

Download or read book Advancing Healthcare Through Personalized Medicine written by Priya Hays and published by Springer Nature. This book was released on 2021-09-27 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases

Author : Ioana Agache
Publisher : Academic Press
ISBN 13 : 0128134720
Total Pages : 236 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Implementing Precision Medicine in Best Practices of Chronic Airway Diseases by : Ioana Agache

Download or read book Implementing Precision Medicine in Best Practices of Chronic Airway Diseases written by Ioana Agache and published by Academic Press. This book was released on 2018-09-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases with a goal of promoting optimal control of disease, higher patient satisfaction and disease prevention. As medical research continues to fund this area, the book highlights the need for implementation of the principles of precision medicine into the bedside management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted whereby treatment is tailored to the level of the individual patient.Written for basic researchers, medical doctors and other healthcare practitioners this book provides guidance on the implementation of the principles of precision medicine into further research and daily clinical practice. - Bridges the gap between precision medicine research and the implementation of the principles into daily clinical practice - Includes contributions from key opinion leaders in the field of airway disease giving a worldwide perspective - Discusses precision medicine in terms of personalized and stratified medicine, biomarkers, prediction of success, participation of the patient and prevention of disease

Toward Precision Medicine

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309222222
Total Pages : 142 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Toward Precision Medicine by : National Research Council

Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Personalized Medicine in Healthcare Systems

Author : Nada Bodiroga-Vukobrat
Publisher : Springer
ISBN 13 : 3030164659
Total Pages : 405 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Personalized Medicine in Healthcare Systems by : Nada Bodiroga-Vukobrat

Download or read book Personalized Medicine in Healthcare Systems written by Nada Bodiroga-Vukobrat and published by Springer. This book was released on 2019-08-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers scientific contributions on comprehensive approaches to personalized medicine. In a systematic and clear manner, it provides extensive information on the methodological, technological, and clinical aspects of high-throughput analytics, nanotechnology approaches, microbiota/human interactions, in-vitro fertilization and preimplantation, and various diseases like cancer.Moreover, the book analyzes the social and legal aspects of social security systems, healthcare systems and EU law – e.g. the role of solidarity, regulatory possibilities and obstacles, justice and equality, privacy/disclosure of data, and the right to know – from an interdisciplinary perspective. Lastly, it explores the economical and ethical context in the fields of business models, intellectual property issues, the patient/physician relationship, and price discrimination.

Digital Health in Focus of Predictive, Preventive and Personalised Medicine

Author : Lotfi Chaari
Publisher : Springer Nature
ISBN 13 : 3030498158
Total Pages : 164 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Digital Health in Focus of Predictive, Preventive and Personalised Medicine by : Lotfi Chaari

Download or read book Digital Health in Focus of Predictive, Preventive and Personalised Medicine written by Lotfi Chaari and published by Springer Nature. This book was released on 2020-09-30 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The edition will cover proceedings of the second International conference on digital health Technologies (ICDHT 2019). The conference will address the topic of P4 medicine from the information technology point of view, and will be focused on the following topics: - Artificial Intelligence for health • Knowledge extraction • Decision-aid systems • Data analysis and risk prediction • Machine learning, deep learning - Health data processing • Data preprocessing, cleaning, management and mining • Computer-aided detection • Big data analysis, prediction and prevention • Cognitive algorithms for healthcare handling dynamic context management • Augmented reality, Motion detection and activity recognition - Devices, infrastructure and communication • Wearable & connected devices • Communication infrastructures, architectures and standards Blockchain for e-Health • Computing/storage infrastructures for e-Health • IoT devices & architectures for Smart Healthcare - Health information systems • Telemedicine, Teleservices • Computing/storage infrastructures for e-Health • Clinical Data Visualisation Standards - Security and privacy for e-health • Health data Analytics for Security and Privacy • E-health Software and Hardware Security • Embedded Security for e-health - Applications in P4 medicine

Personalized Hip and Knee Joint Replacement

Author : Charles Rivière
Publisher : Springer Nature
ISBN 13 : 3030242439
Total Pages : 346 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Personalized Hip and Knee Joint Replacement by : Charles Rivière

Download or read book Personalized Hip and Knee Joint Replacement written by Charles Rivière and published by Springer Nature. This book was released on 2020-06-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes and illustrates the surgical techniques, implants, and technologies used for the purpose of personalized implantation of hip and knee components. This new and flourishing treatment philosophy offers important benefits over conventional systematic techniques, including component positioning appropriate to individual anatomy, improved surgical reproducibility and prosthetic performance, and a reduction in complications. The techniques described in the book aim to reproduce patients’ native anatomy and physiological joint laxity, thereby improving the prosthetic hip/knee kinematics and functional outcomes in the quest of the forgotten joint. They include kinematically aligned total knee/total hip arthroplasty, partial knee replacement, and hip resurfacing. The relevance of available and emerging technological tools for these personalized approaches is also explained, with coverage of, for example, robotics, computer-assisted surgery, and augmented reality. Contributions from surgeons who are considered world leaders in diverse fields of this novel surgical philosophy make this open access book will invaluable to a wide readership, from trainees at all levels to consultants practicing lower limb surgery

Personalized Medicine as Innovation

Author : Katharina Kichko
Publisher : Springer Nature
ISBN 13 : 3658278439
Total Pages : 375 pages
Book Rating : 4.6/5 (582 download)

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Book Synopsis Personalized Medicine as Innovation by : Katharina Kichko

Download or read book Personalized Medicine as Innovation written by Katharina Kichko and published by Springer Nature. This book was released on 2019-09-21 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Katharina Kichko supports the first Personalized Medicine learnings as she provides an approach overview in general as well as reimbursement and regulatory policies in particular. In focus stays analysis of the current Personalized Medicine in the U.S. and Germany as well as its preconditions for a wider implementation in the medical practice. Results have shown that the U.S. – as early knower – have the most projects as well as personalized drugs and therapies, while Germany – as a follower – has a significant number of projects and personalized products and more to come in future.

Realizing the Promise of Precision Medicine

Author : Paul Cerrato
Publisher : Academic Press
ISBN 13 : 0128116366
Total Pages : 220 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Realizing the Promise of Precision Medicine by : Paul Cerrato

Download or read book Realizing the Promise of Precision Medicine written by Paul Cerrato and published by Academic Press. This book was released on 2017-08-24 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases. - Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine - Includes sidebars with more details on specific topics for a complementary, deeper understanding of the main text - Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients

Personalized Medicine

Author : Barbara Prainsack
Publisher : NYU Press
ISBN 13 : 1479856908
Total Pages : 287 pages
Book Rating : 4.4/5 (798 download)

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Book Synopsis Personalized Medicine by : Barbara Prainsack

Download or read book Personalized Medicine written by Barbara Prainsack and published by NYU Press. This book was released on 2017-12-19 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside today's data-driven personalized medicine, and the time, effort, and information required from patients to make it a reality Medicine has been personal long before the concept of “personalized medicine” became popular. Health professionals have always taken into consideration the individual characteristics of their patients when diagnosing, and treating them. Patients have cared for themselves and for each other, contributed to medical research, and advocated for new treatments. Given this history, why has the notion of personalized medicine gained so much traction at the beginning of the new millennium? Personalized Medicine investigates the recent movement for patients’ involvement in how they are treated, diagnosed, and medicated; a movement that accompanies the increasingly popular idea that people should be proactive, well-informed participants in their own healthcare. While it is often the case that participatory practices in medicine are celebrated as instances of patient empowerment or, alternatively, are dismissed as cases of patient exploitation, Barbara Prainsack challenges these views to illustrate how personalized medicine can give rise to a technology-focused individualism, yet also present new opportunities to strengthen solidarity. Facing the future, this book reveals how medicine informed by digital, quantified, and computable information is already changing the personalization movement, providing a contemporary twist on how medical symptoms or ailments are shared and discussed in society. Bringing together empirical work and critical scholarship from medicine, public health, data governance, bioethics, and digital sociology, Personalized Medicine analyzes the challenges of personalization driven by patient work and data. This compelling volume proposes an understanding that uses novel technological practices to foreground the needs and interests of patients, instead of being ruled by them.

Precision Community Health

Author : Bechara Choucair
Publisher : Island Press
ISBN 13 : 164283016X
Total Pages : 224 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Precision Community Health by : Bechara Choucair

Download or read book Precision Community Health written by Bechara Choucair and published by Island Press. This book was released on 2020-05-28 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Bechara Choucair was a young doctor, he learned an important lesson: treating a patient for hypothermia does little good if she has to spend the next night out in the freezing cold. As health commissioner of Chicago, he was determined to address the societal causes of disease and focus the city’s resources on its most vulnerable populations. That targeted approach has led to dramatic successes, such as lowering rates of smoking, teen pregnancy, breast cancer mortalities, and other serious ills. In Precision Community Health, Choucair shows how those successes can be replicated and expanded around the country. The key is to use advanced technologies to identify which populations are most at risk for specific health threats and avert crises before they begin. Big data makes precision community health possible. But in our increasingly complex world, we also need new strategies for developing effective coalitions, media campaigns, and policies. This book showcases four innovations that move public health departments away from simply dispensing medical care and toward supporting communities to achieve true well-being. The approach Choucair pioneered in Chicago requires broadening our thinking about what constitutes public health. It is not simply about access to a doctor, but access to decent housing, jobs, parks, food, and social support. It also means acknowledging that a one-size-fits-all strategy may exacerbate inequities. By focusing on those most in need, we create an agenda that is simultaneously more impactful and more achievable. The result is a wholesale change in the way public health is practiced and in the well-being of all our communities.

Precision Medicine and Artificial Intelligence

Author : Michael Mahler
Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 302 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Precision Medicine and Artificial Intelligence by : Michael Mahler

Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Handbook of Personalized Medicine

Author : Ioannis S. Vizirianakis
Publisher : CRC Press
ISBN 13 : 9814411191
Total Pages : 1562 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Handbook of Personalized Medicine by : Ioannis S. Vizirianakis

Download or read book Handbook of Personalized Medicine written by Ioannis S. Vizirianakis and published by CRC Press. This book was released on 2014-02-12 with total page 1562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Genomics and Personalized Medicine

Author : Michael Snyder
Publisher : Oxford University Press
ISBN 13 : 0190234784
Total Pages : 185 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Genomics and Personalized Medicine by : Michael Snyder

Download or read book Genomics and Personalized Medicine written by Michael Snyder and published by Oxford University Press. This book was released on 2016-02-09 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2001 the Human Genome Project succeeded in mapping the DNA of humans. This landmark accomplishment launched the field of genomics, the integrated study of all the genes in the human body and the related biomedical interventions that can be tailored to benefit a person's health. Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual's genetic sequence -- their genome -- against known elements of "Big Data," elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution is limitless. This entry in the What Everyone Needs to Know series offers an authoritative resource on the prospects and realities of genomics and personalized medicine. As this science continues to alter traditional medical paradigms, consumers are faced with additional options and more complicated decisions regarding their health care. This book provides the essential information everyone needs.

Progress and Challenges in Precision Medicine

Author : Mukesh Verma
Publisher : Academic Press
ISBN 13 : 0128095024
Total Pages : 346 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Progress and Challenges in Precision Medicine by : Mukesh Verma

Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. - Provides an overview of the growing field of precision medicine - Contains chapters from geographically diverse experts in their field - Explores important aspects of precision medicine, including applications, ethics, and development

Personalizing Precision Medicine

Author : Kristin Ciriello Pothier
Publisher : John Wiley & Sons
ISBN 13 : 1118792122
Total Pages : 239 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Personalizing Precision Medicine by : Kristin Ciriello Pothier

Download or read book Personalizing Precision Medicine written by Kristin Ciriello Pothier and published by John Wiley & Sons. This book was released on 2017-08-30 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. She reviews the full continuum of personalizing precision medicine, including diagnostics, therapeutics, big data, supportive care, regulation, and reimbursement and innovation in precision medicine worldwide. • Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide • Reviews precision medicine around the world, including the US, China, Japan, the Middle East, India, Europe, and Latin America • Discusses a number of diseases areas – cancer, cardiovascular, neurodegenerative, infectious disease, pain, immunology, rare diseases • Includes information and quotes from over 100 interviews with key industry experts in biotech, pharma, informatics, diagnostics, health providers, advocacy groups, and more. • Includes stories illustrating current issues and future promises in precision medicine for a human touch

Service Design Practices for Healthcare Innovation

Author : Mario A. Pfannstiel
Publisher : Springer Nature
ISBN 13 : 3030872734
Total Pages : 536 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Service Design Practices for Healthcare Innovation by : Mario A. Pfannstiel

Download or read book Service Design Practices for Healthcare Innovation written by Mario A. Pfannstiel and published by Springer Nature. This book was released on 2022-01-19 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an overview of service design practices for healthcare and hospital management. It explores how these practices can help to generate innovations in healthcare and contribute to the improvement of patient-centered care. Respected experts, including scholars from various disciplines and practitioners from healthcare institutions, share essential insights into established research areas, fields of work and work structures, and discuss successful approaches, methods and tools. By illustrating innovative services, products, processes, systems, and technologies, as well as their application in practice, the authors highlight the role of participating stakeholders in service design projects and the added value that comes from sharing, communicating, networking and collaborating. This book is a must-read for scholars and practitioners in the hospital and healthcare sector. It will also appeal to anyone interested in organizational development, service business model innovation, customer involvement and perceptions, and service experience.