Orthopedic Regenerative Medicine

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Orthobiologics

Author : Giuseppe Filardo
Publisher : Springer Nature
ISBN 13 : 3030847446
Total Pages : 394 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Orthobiologics by : Giuseppe Filardo

Download or read book Orthobiologics written by Giuseppe Filardo and published by Springer Nature. This book was released on 2021-12-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.

Regenerative Treatments in Sports and Orthopedic Medicine

Author : Gerard A. Malanga, MD
Publisher : Springer Publishing Company
ISBN 13 : 1617052892
Total Pages : 305 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Regenerative Treatments in Sports and Orthopedic Medicine by : Gerard A. Malanga, MD

Download or read book Regenerative Treatments in Sports and Orthopedic Medicine written by Gerard A. Malanga, MD and published by Springer Publishing Company. This book was released on 2017-09-28 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine offers physicians new tools to help repair damaged tissue, alleviate pain, accelerate healing, and improve function for patients with degenerative conditions or sports injuries. Regenerative Treatments in Sports and Orthopedic Medicine is the first comprehensive book devoted to orthobiologic treatments for orthopedic conditions. Authored by experts in regenerative medicine, this evidence- and experience-based guide is written for clinicians looking to understand and effectively implement these treatments in their practices. Broad yet focused coverage of the scientific underpinnings, regulatory issues, staffing and equipment, nutritional and rehabilitation concerns, and orthobiologic interventions for specific clinical problems make this the ideal procedural reference for anyone working to restore function to athletes or other patients with musculoskeletal pathologies. Key Features Unparallelled coverage of clinical science and practical applications Written by pioneering leaders at the forefront of an emerging standard of care Evidence-based indications for initiating orthobiologic therapies Includes a review of important nomenclature for the novice Covers both Platelet Rich Plasma (PRP) and stem cell procedures A must-read guide for practitioners in academic and private practice settings

Platelet-Rich Plasma

Author : José Fábio Santos Duarte Lana
Publisher : Springer Science & Business Media
ISBN 13 : 3642401171
Total Pages : 368 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Platelet-Rich Plasma by : José Fábio Santos Duarte Lana

Download or read book Platelet-Rich Plasma written by José Fábio Santos Duarte Lana and published by Springer Science & Business Media. This book was released on 2013-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelet-Rich Plasma (PRP) has gained tremendous popularity in recent years as a treatment option for specialties including Orthopedics, Dentistry, Sports Medicine, Otorhinolaryngology, Neurosurgery, Ophthalmology, Urology, Vascular, Cardiothoracic and Maxillofacial Surgery, and Veterinarian Medicine. Nowadays, PRP and Stem Cell Science have added an exciting dimension to tissue repair. This book begins by giving the reader a broad overview of current progress as well as a discussion of the technical aspects of preparation and therapeutic use of autologous PRP. It is followed by a review of platelet structure, function and major growth factors in PRP (PDGF and TGFβ).The third chapter outlines the basic principles of biochemical cellular metabolism that increases the efficacy of PRP. Analogous to the preparation of soil for a garden, restoring cellular health should be the first consideration in Regenerative Medicine. Standardization of PRP preparation to clinical use still remains a challenging prospect. In this sense, a feasible strategy for studying PRP preparation is illustrated, which also allows to modulate and tailor the quality of PRP for further clinical applications. The science behind PRP and stem cells, on tissue regeneration, cell proliferation and mesenchyme stem-cells are emphasized and reviewed. Various specific uses of PRP are described with detailed illustrations of various personal experiences mainly in orthopedic injuries, ligament and tend on repair, degenerative diseases, sports medicine, chronic wound healing as well as rehabilitation aspects in tendinopathy. Expertly written by leading scientists in the field, this book provides for beginners and experienced readers scientific fundamentals, the state of art of PRP, specific uses and personal experiences with a practical approach and reference for current trends in use. Finally, this book paves the way for future developments.

Orthopedic Regenerative Medicine

Author : Alimorad Farshchian, M.D.
Publisher : AuthorHouse
ISBN 13 : 1438940998
Total Pages : 334 pages
Book Rating : 4.4/5 (389 download)

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Book Synopsis Orthopedic Regenerative Medicine by : Alimorad Farshchian, M.D.

Download or read book Orthopedic Regenerative Medicine written by Alimorad Farshchian, M.D. and published by AuthorHouse. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metabolic Therapies in Orthopedics, Second Edition

Author : Taylor & Francis Group
Publisher : CRC Press
ISBN 13 : 9781032094854
Total Pages : 470 pages
Book Rating : 4.0/5 (948 download)

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Book Synopsis Metabolic Therapies in Orthopedics, Second Edition by : Taylor & Francis Group

Download or read book Metabolic Therapies in Orthopedics, Second Edition written by Taylor & Francis Group and published by CRC Press. This book was released on 2021-06-30 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first medical reference textbook to compile an unprecedented synthesis of evidence for regenerative orthopedics by key opinion leaders Thirty-five authors address your clinical questions What emerging technologies are right for my clinical practice? How can I strengthen my patients before their orthopedic surgery? Practically speaking, how can I leverage the latest metabolic therapies to safeguard my patients from toxins, medications, food and chronic diseases known to adversely affect the musculoskeletal system? "Ask the Author" feature Would you like to discuss a patient with a particular author? Now you can do so at www.betterorthopedics.com. First to be second Did you notice this book is the first book in regenerative orthopedics to publish a second edition? This diverse author team leads the growing field of regenerative orthopedics and offers the broadest and in-depth approach to leveraging metabolic therapies. This book comprises the professional opinion of its authors. It does not claim to represent guidelines, recommendations, or the current standard of medical care.

Atlas of Ultrasound-Guided Musculoskeletal Injections

Author : Gerard Malanga
Publisher : McGraw Hill Professional
ISBN 13 : 0071772049
Total Pages : 478 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Atlas of Ultrasound-Guided Musculoskeletal Injections by : Gerard Malanga

Download or read book Atlas of Ultrasound-Guided Musculoskeletal Injections written by Gerard Malanga and published by McGraw Hill Professional. This book was released on 2014-03-22 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, concise description of more than 100 US-guided injections in musculoskeletal medicine. Atlas of Ultrasound-Guided Musculoskeletal Injections includes numerous tips and tricks from the field's most experienced and respected practitioners. This unique and state-of–the-art text is ideal for physiatrists, rheumatologists, sports medicine physicians, radiologists, pain medicine specialists, and orthopedic surgeons. With a focus on safety and efficacy, this atlas is a worthwhile investment for any practitioner looking to add ultrasound-guided procedures to their practice or is looking to sharpen their skills. The book opens with informative coverage of the fundamentals of MSK US, including ultrasound physics, preparation and set-up for MSK US procedures, and the rationale and evidence for performing these procedures. The main body of the book dedicates one chapter to a specific US-guided injection or procedure. Each chapter design includes sections on key points, pertinent anatomy, common pathology, US imaging, indications, and technique. The book is divided into 8 sections: Shoulder Elbow Hand and wrist Pelvis Knee Foot and ankle Special procedures (rotator cuff, Percutaneous Trigger finger release, Ultrasound-guided Carpal Tunnel release, and Tenex) Atlas of Ultrasound-Guided Musculoskeletal Injections includes coverage of the full spectrum of procedures, ranging from basic US guided joint injections to perinerual injections, tenotomies, and surgical procedures such as percutaneous A1 pulley release, making the book the field's first true cornerstone text and the "go to" resource for any clinician interested in the subject.

Principles of Regenerative Medicine

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0123814235
Total Pages : 1203 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Nanoengineering in Musculoskeletal Regeneration

Author : Mehdi Razavi
Publisher : Academic Press
ISBN 13 : 0128202629
Total Pages : 290 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nanoengineering in Musculoskeletal Regeneration by : Mehdi Razavi

Download or read book Nanoengineering in Musculoskeletal Regeneration written by Mehdi Razavi and published by Academic Press. This book was released on 2020-05-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline-from biomedical discovery to clinical implementation-aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.

Musculoskeletal Tissue Regeneration

Author : William S. Pietrzak
Publisher : Springer Science & Business Media
ISBN 13 : 1597452394
Total Pages : 647 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Musculoskeletal Tissue Regeneration by : William S. Pietrzak

Download or read book Musculoskeletal Tissue Regeneration written by William S. Pietrzak and published by Springer Science & Business Media. This book was released on 2008-04-11 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

Orthopedics 2. 0

Author : Christoper Centeno
Publisher :
ISBN 13 : 9780999477168
Total Pages : pages
Book Rating : 4.4/5 (771 download)

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Book Synopsis Orthopedics 2. 0 by : Christoper Centeno

Download or read book Orthopedics 2. 0 written by Christoper Centeno and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by Dr. Chris Centeno, this e-book delves into the human musculoskeletal system and explains how everything works together in concert to maintain our physical wellbeing. When a single component in this chain is damaged, it can lead to a cascade of joint, spine and connective tissue problems, resulting in chronic pain.Using the Regenexx SANS approach, Orthopedics 2.0 walks you through a series of tests and exercises that you can do on your own to better understand where your own body is struggling to maintain proper stability and alignment, explaining the possible reasons and long term implications along the way. Orthopedics 2.0 also explores how Regenexx is pioneering the new field of Interventional Orthopedics, where the use of regenerative biologic treatments, such as adult stem cell therapy and platelet rich plasma, are being used to help repair and strengthen damaged tissues, as opposed to invasive surgeries that often remove important tissues when a joint or the spine becomes damaged.With hyperlinks to more detailed information, related studies and commentary, this book condenses a vast amount of data and resources into an enjoyable and entertaining read. This is the fourth edition of Orthopedics 2.0 with even more content and graphics.

Cardiac Regeneration

Author : Masaki Ieda
Publisher : Springer
ISBN 13 : 3319561065
Total Pages : 277 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Cardiac Regeneration by : Masaki Ieda

Download or read book Cardiac Regeneration written by Masaki Ieda and published by Springer. This book was released on 2017-10-27 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Articular Cartilage Lesions

Author : Brian J. Cole
Publisher : Springer Science & Business Media
ISBN 13 : 0387215530
Total Pages : 346 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Articular Cartilage Lesions by : Brian J. Cole

Download or read book Articular Cartilage Lesions written by Brian J. Cole and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Cole and Malek, recognized leaders in the field, wrote this cutting-edge text to fill the void in the literature regarding the management of articular cartilage disease and meniscal deficiency. The book enables orthopedic surgeons to develop an evidence-based decision-making framework that guides the management of articular cartilage lesions. Carefully chosen contributors provide readers with a practical background in articular lesions, patient assessment, and management strategies. Subsequent chapters address the gamut of current surgical techniques, from arthroscopy and debridement to unicondylar arthroplasty, in a step-by-step manner. More than 500 detailed illustrations, many in color, help readers understand and master treatments. Case studies, which include preoperative planning and postoperative outcomes, reinforce the decision-making process. Nearly every permutation and treatment option is covered, making this text a prime resource for surgeons committed to exercising sound judgement.

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Orthopedics of the Upper and Lower Limb

Author : K. Mohan Iyer
Publisher : Springer Nature
ISBN 13 : 3030432866
Total Pages : 714 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Orthopedics of the Upper and Lower Limb by : K. Mohan Iyer

Download or read book Orthopedics of the Upper and Lower Limb written by K. Mohan Iyer and published by Springer Nature. This book was released on 2020-07-07 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book provides a practical guide to the latest diagnostic and therapeutic techniques in orthopedics for both the upper and lower limb. Extensively revised chapters provide detailed step-by-step instructions on how to perform basic clinical and surface, anatomy examinations on joints including the hand, elbow and ankle. The application of relevant surgical procedures and post-operative management techniques are also detailed. New topics covered include cruciate ligament injuries, and robot assisted surgery. Orthopedics of the Upper and Lower Limb is an ideal resource for trainees and junior surgeons seeking an easy to follow clinical manual on how to successfully diagnose and treat patients with orthopedic disorders affecting both limbs. It is also of use to the experienced practitioner seeking a detailed resource on the latest advances in the field.

Developmental Biology and Musculoskeletal Tissue Engineering

Author : Martin J. Stoddart
Publisher : Academic Press
ISBN 13 : 0128115386
Total Pages : 272 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Developmental Biology and Musculoskeletal Tissue Engineering by : Martin J. Stoddart

Download or read book Developmental Biology and Musculoskeletal Tissue Engineering written by Martin J. Stoddart and published by Academic Press. This book was released on 2018-04-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. - Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes - Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues - Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering - Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering - Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles

Author : Venkatram Prasad Shastri
Publisher : Springer Science & Business Media
ISBN 13 : 9048187885
Total Pages : 414 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles by : Venkatram Prasad Shastri

Download or read book Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles written by Venkatram Prasad Shastri and published by Springer Science & Business Media. This book was released on 2010-08-14 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.

Advanced Techniques in Bone Regeneration

Author : Alessandro Rozim Zorzi
Publisher : BoD – Books on Demand
ISBN 13 : 9535125389
Total Pages : 388 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Advanced Techniques in Bone Regeneration by : Alessandro Rozim Zorzi

Download or read book Advanced Techniques in Bone Regeneration written by Alessandro Rozim Zorzi and published by BoD – Books on Demand. This book was released on 2016-08-31 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.