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Author : Andrea Sant
Publisher : Frontiers Media SA
ISBN 13 : 2889458849
Total Pages : 183 pages
Book Rating : 4.8/5 (894 download)
Download or read book Orchestration of an Immune Response to Respiratory Pathogens written by Andrea Sant and published by Frontiers Media SA. This book was released on 2019-07-25 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Junkal Garmendía
Publisher : Frontiers Media SA
ISBN 13 : 2889631311
Total Pages : 355 pages
Book Rating : 4.8/5 (896 download)
Download or read book Update on the Immune Mechanisms Against Respiratory Pathogens written by Junkal Garmendía and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiratory infections are leading causes of mortality and morbidity, with Tuberculosis and lower respiratory tract infections (LRTI) culminating in almost 5 million deaths per year. Respiratory tract infections pose a continuous threat to humans due to their easy dissemination via aerial transmission. Children under the age of five living in developing countries are the most susceptible hosts to a plethora of bacteria and viruses including Mycobacterium tuberculosis, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Klebsiella pneumoniae, Bordetella pertussis, Pseudomonas aeruginosa, Mycoplasma pneumoniae, Influenza virus, Respiratory syncytial virus and metapneumovirus. Likewise, adult patients suffering from underlying chronic respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD), bronchiectasis or neutrophilic asthma are also highly targeted by LRTIs. Despite vaccination saving millions of lives, the growing emergence of antibiotic resistant strains is a major challenge for the coming years. In addition, some vaccines against particular respiratory pathogens are ineffective in providing long-term protection. Accordingly, an enhanced understanding of host immunity to respiratory infections is essential for developing new and more effective microbial- and host-directed therapeutics. This eBook will provide a comprehensive overview of the microbial factors and the host immune mechanisms that determine the control of lung infection and/or the development of lung diseases. Manuscripts included in this eBook are divided in four chapters and cover these aspects of immunology against respiratory pathogens: -Pathogen targets for immune recognition including membrane-anchored and secreted effector molecules. -Specific roles of immune cell subsets in response to respiratory infections spanning both innate and adaptive immunity. -Host factors involved in pathogen recognition in the respiratory system including cytosolic DNA sensors. -New prophylactic and/or therapeutic strategies against respiratory infections.
Author : Gee W. Lau
Publisher : Frontiers Media SA
ISBN 13 : 2889666123
Total Pages : 244 pages
Book Rating : 4.8/5 (896 download)
Download or read book Outsmarting the Host: How Bacterial Pathogens Modulate Immune Responses in The Lung written by Gee W. Lau and published by Frontiers Media SA. This book was released on 2021-03-22 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Suzie Hingley-Wilson
Publisher : Frontiers Media SA
ISBN 13 : 2832519164
Total Pages : 297 pages
Book Rating : 4.8/5 (325 download)
Download or read book Mycobacteria and the Macrophage written by Suzie Hingley-Wilson and published by Frontiers Media SA. This book was released on 2023-12-28 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The macrophage (or “big eater”) is often considered the first cell type to encounter the causative agent of Tuberculosis (TB), Mycobacterium tuberculosis, upon entry to the lung. Once inside the macrophage the tubercle bacillus can survive and even replicate where many other invading pathogens perish. Recent research suggests the bacilli adapts within this hostile environment, treating the macrophage like a Trojan horse. Indeed, cutting-edge techniques have revealed that the degree of bacterial heterogeneity and resistance to antibiotics changes within the macrophage. M. tuberculosis spends most of its life cycle within the macrophage and has adopted specific mechanisms to survive, egress and to recruit more of this niche cell (eg the Type VII secretion system ESX-1). Understanding the host-pathogen interaction in tuberculous infection is key to understanding TB, which remains the number one cause of death from a bacterial infection. In this research topic we aim to cover advances in understanding how the tubercle bacillus adapts and survives within the host cell. Determining the responsible mechanisms may reveal novel ways to target this deadly pathogen and halt its adaptation and transformation within these potentially destructive or permissive cells.
Author : Fernanda Mozzi
Publisher : John Wiley & Sons
ISBN 13 : 0813820952
Total Pages : 417 pages
Book Rating : 4.8/5 (138 download)
Download or read book Biotechnology of Lactic Acid Bacteria written by Fernanda Mozzi and published by John Wiley & Sons. This book was released on 2010-01-29 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title represents a broad review of current research on LAB and their novel applications with contributions from a number of well-known leading scientists. The book encompasses a wide range of topics including both traditional and novel developing fields, and provides unparalleled, comprehensive information on new advances of genomics, proteomics, metabolism and biodiversity of LAB. Chapters contain state-of-the-art discussions of specific LAB applications such as their use as probiotics, live vaccines and starter cultures in old and new fermented products. The safety of these microorganisms and their interactions with diverse ecosystems natural biota are also covered as well as the new applications of well-known (bacteriocins) and novel (vitamins, low-calorie sugars, etc.) metabolites produced by LAB. This book is an essential reference for established researchers and scientists, doctoral and post-doctoral students, university professors and instructors, and food technologists working on food microbiology, physiology and biotechnology of lactic acid bacteria.
Author : Sunit K. Singh
Publisher : CRC Press
ISBN 13 : 0429586450
Total Pages : 702 pages
Book Rating : 4.4/5 (295 download)
Download or read book Human Respiratory Viral Infections written by Sunit K. Singh and published by CRC Press. This book was released on 2014-06-23 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary approach, Human Respiratory Viral Infections is set at the level between the definitive reference work and an essential clinical manual. Exploring recent advances in human respiratory viral research, the text builds on the basic sciences of epidemiology, virology, molecular biology, and immunology to cover clinical diagnos
Author : Philip C. Calder
Publisher : CRC Press
ISBN 13 : 1482253984
Total Pages : 555 pages
Book Rating : 4.4/5 (822 download)
Download or read book Nutrition, Immunity, and Infection written by Philip C. Calder and published by CRC Press. This book was released on 2017-10-10 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both nutrition deficiency and overnutrition can have a significant effect on the risk of infection. Nutrition, Immunity, and Infection focuses on the influence of diet on the immune system and how altering one’s diet helps prevent and treat infections and chronic diseases. This book reviews basic immunology and discusses changes in immune function throughout the life course. It features comprehensive chapters on obesity and the role of immune cells in adipose tissue; undernutrition and malnutrition; infant immune maturation; pre- and probiotics; mechanisms of immune regulation by various vitamins and minerals; nutrition and the aging immune system; nutrition interactions with environmental stress; and immunity in the global health arena. Nutrition, Immunity, and Infection describes the various roles of nutrients and other food constituents on immune function, host defense, and resistance to infection. It describes the impact of infection on nutritional status through a translational approach. Chapters bring together molecular, cellular, and experimental studies alongside human trials so that readers can assess both the evidence for the effects of the food component being discussed and the mechanisms underlying those effects. The impact of specific conditions including obesity, anorexia nervosa, and HIV infection is also considered. Chapter authors are experts in nutrition, immunity, and infection from all around the globe, including Europe, Australia, Brazil, India, and the United States. This book is a valuable resource for nutrition scientists, food scientists, dietitians, health practitioners, and students interested in nutrition and immunity.
Author : Steven A. Frank
Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Author : Robert A. Stockley
Publisher : John Wiley & Sons
ISBN 13 : 0470755288
Total Pages : 912 pages
Book Rating : 4.4/5 (77 download)
Download or read book Chronic Obstructive Pulmonary Disease written by Robert A. Stockley and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only international clinical textbook for COPD – one of the top 5 causes of death and disability worldwide The only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatment International team of contributors covers all aspects of COPD – from physiology and epidemiology to diagnosis and treatment Everything the busy physician needs to understand, diagnose and treat the COPD patient: Structure and physiology of the respiratory system Clinical considerations and allied conditions Therapy (including current and developing treatments) Diagnostic tests used in daily practice
Author : Karl Maramorosch
Publisher : Gulf Professional Publishing
ISBN 13 : 9780120398676
Total Pages : 290 pages
Book Rating : 4.3/5 (986 download)
Download or read book Advances in Virus Research written by Karl Maramorosch and published by Gulf Professional Publishing. This book was released on 2005-11-16 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology.
Author : Yvonne J. Huang
Publisher : Springer Nature
ISBN 13 : 3030871045
Total Pages : 308 pages
Book Rating : 4.0/5 (38 download)
Download or read book The Microbiome in Respiratory Disease written by Yvonne J. Huang and published by Springer Nature. This book was released on 2022-01-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the microbiome in respiratory disease, from the initial research study to the disease-specific implications and related applications. Research on the respiratory microbiome is increasing in volume and scope. This reflects rapidly growing interest in the study of respiratory disease to understand how microbiota shape mechanisms of disease pathogenesis. The respiratory tract spans the nasal passages, sinus cavities, oropharynx, and the tracheobronchial tree of the lungs. In these compartments of the upper and lower respiratory tract, the microbiota have now been studied in the context of several chronic respiratory conditions. These include chronic sinusitis, allergic rhinitis, asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis and pulmonary fibrosis, to name a few. The potential impact of ecological interactions (i.e., between microbes and between microbiota and host) within and across respiratory compartments is increasingly recognized. The book is organized into two main sections. Part I, Principles and Tools, covers conceptual modeling of the respiratory microbiome, experimental methodology with a focus on a priori considerations in study design and sampling, laboratory and computational methods for analysis of respiratory microbiome data, and minimizing interpretive pitfalls. Part II, Applications, discusses the evidence from specific studies that have shed novel insights into the influence of respiratory microbiota on mechanisms or outcomes in specific diseases. Based on current best evidence, disease-specific chapters include chronic rhinosinusitis, asthma (pediatric and adult studies), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), bronchiectasis not due to CF, idiopathic pulmonary fibrosis, and lung transplant. This is an ideal reference for forward-thinking practitioners with interest in novel developments in precision medicine applications in lung disease, as well as translational scientists in the field of microbiology, immunology and lung biology.
Author : Klemens Horst
Publisher : Frontiers Media SA
ISBN 13 : 2832512100
Total Pages : 119 pages
Book Rating : 4.8/5 (325 download)
Download or read book Translational immunology in trauma - to provide new insights for improving outcomes written by Klemens Horst and published by Frontiers Media SA. This book was released on 2023-01-27 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael J. Cox
Publisher : European Respiratory Society
ISBN 13 : 1849841020
Total Pages : 261 pages
Book Rating : 4.8/5 (498 download)
Download or read book The Lung Microbiome written by Michael J. Cox and published by European Respiratory Society. This book was released on 2019-03-01 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.
Author : Oleg Eremin
Publisher : Oxford University Press, USA
ISBN 13 : 019958687X
Total Pages : 547 pages
Book Rating : 4.1/5 (995 download)
Download or read book Essential Immunology for Surgeons written by Oleg Eremin and published by Oxford University Press, USA. This book was released on 2011-04-28 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the necessary foundation for a critical understanding of this rapidly expanding area of biological science that underpins and explains the modern concepts of a wide range of diseases and conditions, this book gives a concise, readable, and up-to-date account of immunology in general and its translation into key areas of clinical practice.
Author : Kurt Blaser
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805586280
Total Pages : 243 pages
Book Rating : 4.8/5 (55 download)
Download or read book T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases written by Kurt Blaser and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art in cellular and molecular mechanisms regulating the immune response in allergic inflammation. Special attention is given to the central role of regulatory T cells (Treg) in immune regulation and induction of peripheral tolerance, as well as to the relevance of Th17 cells in chronic inflammation. The importance of Treg and Th17 cells is demonstrated in bronchial asthma, atopic eczema, contact dermatitis and delayed-type hypersensitivity. Furthermore, T-cell-mediated regulatory mechanisms in helminthic infections and fungal allergy are discussed. Several chapters are devoted to the therapeutic consequences that these recently discovered T-cell functions may have. Their role as a potential target for specific immunotherapy is evaluated and novel approaches for peripheral tolerance induction and treatment of allergic and asthmatic diseases and inflammation are suggested. Stem cell transplantation as a future therapeutic intervention in regulatory T-cell disorders is also considered. Well edited and up to date, this volume is recommended reading for allergologists, immunologists, dermatologists and any scientist interested in the immunological events regulating allergic inflammation in general and allergic manifestations in different organs.
Author : Michael Gleeson
Publisher : Elsevier Health Sciences
ISBN 13 : 0443101183
Total Pages : 338 pages
Book Rating : 4.4/5 (431 download)
Download or read book Immune Function in Sport and Exercise written by Michael Gleeson and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the risk of immunodepression and infection in athletes. Further chapters explore different ways of measuring immune function, as well as the effects of heavy training on innate and specific (acquired) immunity, exercise in environmental extremes, and nutrition. Connections between exercise, infection risk, and immune function in special populations (elderly, obese, diabetic and HIV patients) are also addressed. Authored by a team of highly experienced experts. The "J-shaped" relationship between exercise load and infection risk is described, backed by current research and evidence. Components of the immune system and normal immune function are explained in detail, as well as methods for measuring immune function. The impact of acute and chronic psychological stress on immune function is presented, along with suggestions for minimizing the risk of immunodepression and infection in athletes. The effects of heavy training, exercise in environmental extremes, and nutrition are discussed with regard to their impact on innate and specific (acquired) immunity. Immune function in special populations (elderly, obese, diabetic and HIV patients) is also addressed, exploring links between exercise and infection risk in these groups. Evidence-based coverage includes a list of references in each chapter, as well as suggestions for further reading that direct readers to important texts and review articles. Information is presented in an easily accessible format, following a logical progression of material. LEach chapter begins with a list of learning objectives and ends with a list of key points to reinforce learning. A glossary at the end of the book defines all key terms and abbreviations.
Author : A Wesley Burks
Publisher : Elsevier Health Sciences
ISBN 13 : 0323546986
Total Pages : 1840 pages
Book Rating : 4.3/5 (235 download)
Download or read book Middleton's Allergy E-Book written by A Wesley Burks and published by Elsevier Health Sciences. This book was released on 2019-09-25 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through eight outstanding editions, Middleton’s Allergy: Principles and Practice has been the reference of choice for both clinicians and researchers as both a practical reference and an effective self-assessment tool for board preparation. The 9th Edition continues the tradition of excellence with comprehensive coverage of all basic science and clinical applications regarding allergy practice and disease mechanisms. It brings you fully up to date with recent innovations in the diagnosis, prevention, and management of allergic disorders, including emerging global issues, the advent of precision medicine, and new immunologic therapies. Offers unparalleled depth and up-to-date guidance on the full spectrum of allergy across the lifespan, with significant updates throughout. Contains new chapters on Innate Lymphoid Cells, Systems Biology, and Treatment of Primary Immunodeficiency Diseases. Discusses emerging topics such as epidemic thunderstorm asthma and precision medicine in allergic disorders. Features more than 730 full-color illustrations, including many new cellular and molecular drawings of disease mechanisms. Includes new Summary of Important Concepts boxes, plus new multiple-choice questions online with explanations and answers. Features a new team of expert editors and more international contributors for a global perspective of this complex field.
