OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 404: Acute Dermal Irritation/Corrosion

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Publisher : OECD Publishing
ISBN 13 : 9264242678
Total Pages : 8 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 404: Acute Dermal Irritation/Corrosion by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 404: Acute Dermal Irritation/Corrosion written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. It recommends sequential testing strategies, which include the performance of validated and accepted in vitro or ex vivo tests for corrosion/irritation.

Test No. 404: Acute Dermal Irritation/Corrosion

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Publisher : OECD Publishing
ISBN 13 : 9264070621
Total Pages : 13 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Test No. 404: Acute Dermal Irritation/Corrosion by : OECD

Download or read book Test No. 404: Acute Dermal Irritation/Corrosion written by OECD and published by OECD Publishing. This book was released on 2002-04-24 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. This Test Guideline recommends sequential testing strategies, which include the performance of validated and ...

Test No. 404: Acute Dermal Irritation/Corrosion

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ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (929 download)

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Book Synopsis Test No. 404: Acute Dermal Irritation/Corrosion by :

Download or read book Test No. 404: Acute Dermal Irritation/Corrosion written by and published by . This book was released on 2015 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. This Test Guideline recommends sequential testing strategies, which include the performance of validated and accepted in vitro or ex vivo tests for corrosion/irritation. The albino rabbit is the preferable laboratory animal. The substance to be tested is applied in a single dose to a small area of skin (approximately 6cm2) of an experimental animal; untreated skin areas of the test animal serve as the control. The exposure period is 4 hours. Residual test substance should then be removed. The dose is 0.5ml (liquid) or 0.5g (solid) applied to the test site. The method consists of two tests: the initial test and the confirmatory test (used only if a corrosive effect is not observed in the initial test). All animals should be examined for signs of erythema and oedema during 14 days. The dermal irritation scores should be evaluated in conjunction with the nature and severity of lesions, and their reversibility or lack of reversibility. When responses persist to the end of the 14-day observation period, the test substance should be considered an irritant.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 405: Acute Eye Irritation/Corrosion

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Publisher : OECD Publishing
ISBN 13 : 926418533X
Total Pages : 13 pages
Book Rating : 4.2/5 (641 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 405: Acute Eye Irritation/Corrosion by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 405: Acute Eye Irritation/Corrosion written by OECD and published by OECD Publishing. This book was released on 2023-07-04 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...

OECD Guidelines for the Testing of Chemicals

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (785 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals by :

Download or read book OECD Guidelines for the Testing of Chemicals written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Test No. 405: Acute Eye Irritation/Corrosion

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Publisher : OECD Publishing
ISBN 13 : 9264070648
Total Pages : 21 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Test No. 405: Acute Eye Irritation/Corrosion by : OECD

Download or read book Test No. 405: Acute Eye Irritation/Corrosion written by OECD and published by OECD Publishing. This book was released on 2002-04-24 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity

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Publisher : OECD Publishing
ISBN 13 : 9264070583
Total Pages : 13 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity written by OECD and published by OECD Publishing. This book was released on 2017-10-09 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method

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Publisher : OECD Publishing
ISBN 13 : 9264242848
Total Pages : 28 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method written by OECD and published by OECD Publishing. This book was released on 2021-06-17 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2.

OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002

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Publisher : OECD Publishing
ISBN 13 : 9264170200
Total Pages : 79 pages
Book Rating : 4.2/5 (641 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002 by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002 written by OECD and published by OECD Publishing. This book was released on 2002-08-14 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD Guidelines for the Testing of Chemicals provide a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as the standard methods for safety testing, the OECD Guidelines for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion

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Publisher : OECD Publishing
ISBN 13 : 9264242791
Total Pages : 13 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated Test Guideline 435 provides an in vitro membrane barrier test method that can be used to identify corrosive chemicals. The test method utilizes an artificial membrane designed to respond to corrosive chemicals in a manner similar to animal skin in situ.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

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Publisher : OECD Publishing
ISBN 13 : 9264070605
Total Pages : 20 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification Systems for Skin Irritation/Corrosion in OECD Member Countries

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Publisher : OECD Publishing
ISBN 13 : 9264078347
Total Pages : 29 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification Systems for Skin Irritation/Corrosion in OECD Member Countries by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification Systems for Skin Irritation/Corrosion in OECD Member Countries written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: is detailed review document examines member country classification systems for skin irritation/corrosion.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure

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Publisher : OECD Publishing
ISBN 13 : 9264284168
Total Pages : 20 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER)

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Publisher : OECD Publishing
ISBN 13 : 9264242732
Total Pages : 15 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER) by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER) written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline addresses the human health endpoint skin corrosion. It is based on the rat skin transcutaneous electrical resistance (TER) test method, which utilizes skin discs to identify corrosives by their ability to produce a loss of normal stratum corneum integrity and barrier function.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study

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Publisher : OECD Publishing
ISBN 13 : 9264070761
Total Pages : 9 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage

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Publisher : OECD Publishing
ISBN 13 : 9264488804
Total Pages : 32 pages
Book Rating : 4.2/5 (644 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage written by OECD and published by OECD Publishing. This book was released on 2024-06-25 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro macromolecular test method is a biochemical in vitro test method that can be used to identify chemicals (substances and mixtures) that have the potential to induce serious eye damage as well as chemicals not requiring classification for eye irritation or serious eye damage.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method

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Publisher : OECD Publishing
ISBN 13 : 9264071008
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.