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Oecd Guidelines For The Testing Of Chemicals Oecd Guidelines For The Testing Of Chemicals Fourteenth Addendum May 2002
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Book Synopsis OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002 by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002 written by OECD and published by OECD Publishing. This book was released on 2002-08-14 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD Guidelines for the Testing of Chemicals provide a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as the standard methods for safety testing, the OECD Guidelines for ...
Author :Organisation for Economic Co-operation and Development Publisher :Organisation for Economic Co-operation and Development ; [Montréal : Renouf] ISBN 13 :9789264122215 Total Pages : pages Book Rating :4.1/5 (222 download)
Book Synopsis OECD Guidelines for Testing of Chemicals by : Organisation for Economic Co-operation and Development
Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fifteenth Addendum - 2004 by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fifteenth Addendum - 2004 written by OECD and published by OECD Publishing. This book was released on 2004-10-07 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2002-12-12 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.
Book Synopsis OECD Key Publications Catalogue by : Organisation for Economic Co-operation and Development
Download or read book OECD Key Publications Catalogue written by Organisation for Economic Co-operation and Development and published by . This book was released on 2004 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemicals in the Environment by : R M Harrison
Download or read book Chemicals in the Environment written by R M Harrison and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rising concern in recent years over the possible adverse environmental consequences of the use of chemicals has led to a steady increase in national activity towards greater regulation, as well as voluntary agreements with manufacturers for risk management of certain products. This book begins by reviewing the current framework of legislation for the regulation of chemicals in the UK and then reports expert views on both the current situation and possible future developments. Subsequent chapters consider some of the scientific and technical issues, including the evaluation of the risks which chemicals can pose to human life and the environment, and the problems relating to evaluating the risks associated with metals in the environment. Finally, the predictive methods used to model the behaviour of organic chemicals within the environment are described. Highly topical, and with authoritative contributions from international experts, this book covers both the scientific underpinning and the legislative and practical issues of this emotive subject. The detailed coverage of a topic that affects many sectors of industry and society will make it popular with a wide audience of individuals from government organisations, industry or academic research, particularly those in environmental chemistry sectors.
Book Synopsis HMSO Agency Catalogue by : Great Britain. Her Majesty's Stationery Office
Download or read book HMSO Agency Catalogue written by Great Britain. Her Majesty's Stationery Office and published by . This book was released on 2002 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD Workshop on Sharing Information about New Industrial Chemicals Assessment by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD Workshop on Sharing Information about New Industrial Chemicals Assessment written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document contains the report of the OECD Workshop on Sharing Information about New Industrial Chemicals Assessment.
Book Synopsis Alternatives for Dermal Toxicity Testing by : Chantra Eskes
Download or read book Alternatives for Dermal Toxicity Testing written by Chantra Eskes and published by Springer. This book was released on 2017-11-21 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Book Synopsis Mutagenic Impurities by : Andrew Teasdale
Download or read book Mutagenic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2022-02-15 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...
Book Synopsis OECD Style Guide Third Edition by : OECD
Download or read book OECD Style Guide Third Edition written by OECD and published by OECD Publishing. This book was released on 2015-10-12 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of the OECD Style Guide is designed to help draft and organise published material so that readers can easily navigate, understand and access OECD analysis, statistics and information.
Book Synopsis Aquatic Toxicology and Hazard Evaluation by : F. L. Mayer
Download or read book Aquatic Toxicology and Hazard Evaluation written by F. L. Mayer and published by ASTM International. This book was released on 1977 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Computational Toxicology by : Huixiao Hong
Download or read book Advances in Computational Toxicology written by Huixiao Hong and published by Springer. This book was released on 2019-05-21 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and specifically features its application in regulatory decision making. The authors from various government agencies such as FDA, NCATS and NIEHS industry, and academic institutes share their real-world experience and discuss most current practices in computational toxicology and potential applications in regulatory science. Among the topics covered are molecular modeling and molecular dynamics simulations, machine learning methods for toxicity analysis, network-based approaches for the assessment of drug toxicity and toxicogenomic analyses. Offering a valuable reference guide to computational toxicology and potential applications in regulatory science, this book will appeal to chemists, toxicologists, drug discovery and development researchers as well as to regulatory scientists, government reviewers and graduate students interested in this field.
Book Synopsis Toxicity Testing for Assessment of Environmental Agents by : National Research Council
Download or read book Toxicity Testing for Assessment of Environmental Agents written by National Research Council and published by National Academies Press. This book was released on 2006-04-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.
Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel
Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
