Amyotrophic Lateral Sclerosis in Veterans

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Author :
Publisher : National Academies Press
ISBN 13 : 0309180791
Total Pages : 62 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Amyotrophic Lateral Sclerosis in Veterans by : Institute of Medicine

Download or read book Amyotrophic Lateral Sclerosis in Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-27 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyotrophic lateral sclerosis (ALS) our Lou Gehrig's disease is a fatal, mostly non-familial disease that affects the nervous system of humans by causing the degeneration of nerve cells in the brain and spinal cord. The degeneration halts communication between the nervous system and voluntary muscles in the body. This leads to muscle paralysis and eventually the muscles that aid in breathing are affect; causing respiration to fail. The disease, which affects 20,000-30,000 men and women in the United States at any given time, has no effective treatment; most people with ALS die from respiratory failure within 5 years of the onset of symptoms. Recent epidemiologic studies report an association between the development of ALS and prior service in the U.S. military. The studies evaluated either veterans of the 1991 Persian Gulf War or veterans who served in the military in the period 1910-1982. Due to these findings, the Department of Veterans Affairs (VA) asked the National Academies to conduct an assessment of the potential relationship between military service and the later development of ALS. The project was assigned to the Institute of Medicine (IOM), which appointed a committee and gave it the task of evaluating the scientific literature on ALS in veterans. The committee began its work by identifying medical and scientific literature on ALS. PubMed, a database created and managed by the National Library of Medicine. Amyotrophic Lateral Sclerosis in Veterans; Review of the Scientific Literature presents the findings of this committee. The committee reviewed, evaluated, and summarized the scientific literature on ALS in veterans, composed primarily of peer-reviewed, published literature. This report includes the recommendations of the committee.

Gulf War and Health

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Author :
Publisher : National Academies Press
ISBN 13 : 0309168414
Total Pages : 617 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gulf War and Health by : Institute of Medicine

Download or read book Gulf War and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-10 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gulf War and Health, Volume 2, is the second in a series of congressionally-mandated studies by the Institute of Medicine that provides a comprehensive assessment of the available scientific literature on potential health effects of exposure to certain biological, chemical, and environmental agents associated with the Gulf War. In this second study, the committee evaluated the published, peer-reviewed literature on exposure to insecticides and solvents thought to have been present during the 1990-1991 war. Because little information exists on actual exposure levels â€" a critical factor when assessing health effects â€" the committee could not draw specific conclusions about the health problems of Gulf War veterans. However, the study found some evidence, although usually limited, to link specific long-term health outcomes with exposure to certain insecticides and solvents. The next phase of the series will examine the literature on potential health effects associated with exposure to selected environmental pollutants and particulates, such as oil-well fires and jet fuels.

Amyotrophic Lateral Sclerosis in Veterans

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Author :
Publisher : National Academies Press
ISBN 13 : 0309102545
Total Pages : 62 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Amyotrophic Lateral Sclerosis in Veterans by : Institute of Medicine

Download or read book Amyotrophic Lateral Sclerosis in Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 2006-11-27 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyotrophic lateral sclerosis (ALS) our Lou Gehrig's disease is a fatal, mostly non-familial disease that affects the nervous system of humans by causing the degeneration of nerve cells in the brain and spinal cord. The degeneration halts communication between the nervous system and voluntary muscles in the body. This leads to muscle paralysis and eventually the muscles that aid in breathing are affect; causing respiration to fail. The disease, which affects 20,000-30,000 men and women in the United States at any given time, has no effective treatment; most people with ALS die from respiratory failure within 5 years of the onset of symptoms. Recent epidemiologic studies report an association between the development of ALS and prior service in the U.S. military. The studies evaluated either veterans of the 1991 Persian Gulf War or veterans who served in the military in the period 1910-1982. Due to these findings, the Department of Veterans Affairs (VA) asked the National Academies to conduct an assessment of the potential relationship between military service and the later development of ALS. The project was assigned to the Institute of Medicine (IOM), which appointed a committee and gave it the task of evaluating the scientific literature on ALS in veterans. The committee began its work by identifying medical and scientific literature on ALS. PubMed, a database created and managed by the National Library of Medicine. Amyotrophic Lateral Sclerosis in Veterans; Review of the Scientific Literature presents the findings of this committee. The committee reviewed, evaluated, and summarized the scientific literature on ALS in veterans, composed primarily of peer-reviewed, published literature. This report includes the recommendations of the committee.

Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan

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Author :
Publisher : National Academies Press
ISBN 13 : 030921758X
Total Pages : 192 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan by : Institute of Medicine

Download or read book Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-31 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many veterans returning from the conflicts in Iraq and Afghanistan have health problems they believe are related to their exposure to the smoke from the burning of waste in open-air "burn pits" on military bases. Particular controversy surrounds the burn pit used to dispose of solid waste at Joint Base Balad in Iraq, which burned up to 200 tons of waste per day in 2007. The Department of Veterans Affairs asked the IOM to form a committee to determine the long-term health effects from exposure to these burn pits. Insufficient evidence prevented the IOM committee from developing firm conclusions. This report, therefore, recommends that, along with more efficient data-gathering methods, a study be conducted that would evaluate the health status of service members from their time of deployment over many years to determine their incidence of chronic diseases.

Imaging in Neurodegenerative Disorders

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Publisher : Oxford University Press, USA
ISBN 13 : 0199671613
Total Pages : 585 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Imaging in Neurodegenerative Disorders by : Luca Saba

Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by Oxford University Press, USA. This book was released on 2015 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.

Human Subjects Research Regulation

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Author :
Publisher : MIT Press
ISBN 13 : 0262320835
Total Pages : 393 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Human Subjects Research Regulation by : I. Glenn Cohen

Download or read book Human Subjects Research Regulation written by I. Glenn Cohen and published by MIT Press. This book was released on 2014-07-25 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts from different disciplines offer novel ideas for improving research oversight and protection of human subjects. The current framework for the regulation of human subjects research emerged largely in reaction to the horrors of Nazi human experimentation, revealed at the Nuremburg trials, and the Tuskegee syphilis study, conducted by U.S. government researchers from 1932 to 1972. This framework, combining elements of paternalism with efforts to preserve individual autonomy, has remained fundamentally unchanged for decades. Yet, as this book documents, it has significant flaws—including its potential to burden important research, overprotect some subjects and inadequately protect others, generate inconsistent results, and lag behind developments in how research is conducted. Invigorated by the U.S. government's first steps toward change in over twenty years, Human Subjects Research Regulation brings together the leading thinkers in this field from ethics, law, medicine, and public policy to discuss how to make the system better. The result is a collection of novel ideas—some incremental, some radical—for the future of research oversight and human subject protection. After reviewing the history of U.S. research regulations, the contributors consider such topics as risk-based regulation; research involving vulnerable populations (including military personnel, children, and prisoners); the relationships among subjects, investigators, sponsors, and institutional review boards; privacy, especially regarding biospecimens and tissue banking; and the possibility of fundamental paradigm shifts. Contributors Adam Braddock, Alexander Morgan Capron, Ellen Wright Clayton, I. Glenn Cohen, Susan Cox, Amy L. Davis, Hilary Eckert, Barbara J. Evans, Nir Eyal, Heidi Li Feldman, Benjamin Fombonne, Elisa A. Hurley, Ana S. Iltis, Gail H. Javitt, Greg Koski, Nicole Lockhart, Holly Fernandez Lynch, Michael McDonald, Michelle N. Meyer, Osagie K. Obasogie, Efthimios Parasidis, Govind Persad, Rosamond Rhodes, Suzanne M. Rivera, Zachary M. Schrag, Seema K. Shah, Jeffrey Skopek, Laura Stark, Patrick Taylor, Anne Townsend, Carol Weil, Brett A. Williams, Leslie E. Wolf

Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations

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Author :
Publisher : National Academies Press
ISBN 13 : 0309679109
Total Pages : 271 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations by : National Academies of Sciences, Engineering, and Medicine

Download or read book Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-10-23 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 3.7 million U.S. service members have participated in operations taking place in the Southwest Asia Theater of Military Operations since 1990. These operations include the 1990-1991 Persian Gulf War, a post-war stabilization period spanning 1992 through September 2001, and the campaigns undertaken in the wake of the September 11, 2001, attacks. Deployment to Iraq, Kuwait, Saudi Arabia, Bahrain, Gulf of Aden, Gulf of Oman, Oman, Qatar, the United Arab Emirates, and Afghanistan exposed service members to a number of airborne hazards, including oil-well fire smoke, emissions from open burn pits, dust and sand suspended in the air, and exhaust from diesel vehicles. The effects of these were compounded by stressors like excessive heat and noise that are inevitable attributes of service in a combat environment. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations reviews the scientific evidence regarding respiratory health outcomes in veterans of the Southwest Asia conflicts and identifies research that could feasibly be conducted to address outstanding questions and generate answers, newly emerging technologies that could aid in these efforts, and organizations that the Veterans Administration might partner with to accomplish this work.

Gulf War and Health

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Author :
Publisher : National Academies Press
ISBN 13 : 9780309071789
Total Pages : 426 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Gulf War and Health by : Institute of Medicine

Download or read book Gulf War and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2000-12-28 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The men and women who served in the Gulf War theater were potentially exposed to a wide range of biological and chemical agents. Gulf War and Health: Volume 1 assesses the scientific literature concerning the association between these agents and the adverse health effects currently experienced by a large number of veterans.

Air Quality Guidelines

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Author :
Publisher : World Health Organization
ISBN 13 : 9289021926
Total Pages : 497 pages
Book Rating : 4.2/5 (89 download)

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Book Synopsis Air Quality Guidelines by : World Health Organization

Download or read book Air Quality Guidelines written by World Health Organization and published by World Health Organization. This book was released on 2006 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents revised guideline values for the four most common air pollutants - particulate matter, ozone, nitrogen dioxide and sulfur dioxide - based on a recent review of the accumulated scientific evidence. The rationale for selection of each guideline value is supported by a synthesis of information emerging from research on the health effects of each pollutant. As a result, these guidelines now also apply globally. They can be read in conjunction with Air quality guidelines for Europe, 2nd edition, which is still the authority on guideline values for all other air pollutants. As well as revised guideline values, this book makes a brief yet comprehensive review of the issues affecting the application of the guidelines in risk assessment and policy development. Further, it summarizes information on: . pollution sources and levels in various parts of the world, . population exposure and characteristics affecting sensitivity to pollution, . methods for quantifying the health burden of air pollution, and . the use of guidelines in developing air quality standards and other policy tools. Finally, the special case of indoor air pollution is explored. Prepared by a large team of renowned international experts who considered conditions in various parts of the globe, these guidelines are applicable throughout the world. They provide reliable guidance for policy-makers everywhere when considering the various options for air quality management.

The Irritable Heart

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Publisher : W. W. Norton & Company
ISBN 13 : 9780393019568
Total Pages : 444 pages
Book Rating : 4.0/5 (195 download)

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Book Synopsis The Irritable Heart by : Jeff Wheelwright

Download or read book The Irritable Heart written by Jeff Wheelwright and published by W. W. Norton & Company. This book was released on 2001 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wheelwright (former science editor for Life magazine) profiles five ailing Gulf War veterans from their deployment to the Gulf, through their experiences in the Gulf War, and their subsequent illnesses and attempts to discover the causes. He argues that the illnesses belong in the company of chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivity. Pointing out precedents in military history that go back as far as a Civil War malady known as "irritable heart," he argues that the illnesses are a combination of physical symptoms greatly magnified by psychological distress. Because modern medicine deals with the body and mind separately, he contends, the health investigation of the veteran's illnesses is bound to fail. Annotation copyrighted by Book News Inc., Portland, OR

Neuroepigenomics in Aging and Disease

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Publisher : Springer
ISBN 13 : 3319538896
Total Pages : 520 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Neuroepigenomics in Aging and Disease by : Raul Delgado-Morales

Download or read book Neuroepigenomics in Aging and Disease written by Raul Delgado-Morales and published by Springer. This book was released on 2017-05-18 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington’s disease) and elderly (Alzheimer’s disease, Parkinson’s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases.

Animal Models of Neurological Disorders

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Publisher : Springer
ISBN 13 : 9811059810
Total Pages : 350 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Animal Models of Neurological Disorders by : Puneet Kumar Bansal

Download or read book Animal Models of Neurological Disorders written by Puneet Kumar Bansal and published by Springer. This book was released on 2018-01-17 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.

Contaminated Water Supplies at Camp Lejeune

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Author :
Publisher : National Academies Press
ISBN 13 : 0309136997
Total Pages : 338 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Contaminated Water Supplies at Camp Lejeune by : National Research Council

Download or read book Contaminated Water Supplies at Camp Lejeune written by National Research Council and published by National Academies Press. This book was released on 2009-09-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early 1980s, two water-supply systems on the Marine Corps Base Camp Lejeune in North Carolina were found to be contaminated with the industrial solvents trichloroethylene (TCE) and perchloroethylene (PCE). The water systems were supplied by the Tarawa Terrace and Hadnot Point watertreatment plants, which served enlisted-family housing, barracks for unmarried service personnel, base administrative offices, schools, and recreational areas. The Hadnot Point water system also served the base hospital and an industrial area and supplied water to housing on the Holcomb Boulevard water system (full-time until 1972 and periodically thereafter). This book examines what is known about the contamination of the water supplies at Camp Lejeune and whether the contamination can be linked to any adverse health outcomes in former residents and workers at the base.

Amyotrophic Lateral Sclerosis

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Author :
Publisher : Demos Medical Publishing
ISBN 13 : 1936287439
Total Pages : 280 pages
Book Rating : 4.9/5 (362 download)

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Book Synopsis Amyotrophic Lateral Sclerosis by : Richard S. Bedlack, MD

Download or read book Amyotrophic Lateral Sclerosis written by Richard S. Bedlack, MD and published by Demos Medical Publishing. This book was released on 2013 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyotrophic Lateral Sclerosis: A Patient Care Guide for Clinicians is intended as a practical reference for clinicians caring for ALS patients, and will bring together the collective wisdom of those at the forefront of patient-oriented research and practice. This will be an official project of the ALS Research Group (founded by Dr. Mitsumoto and currently headed by Dr. Bedlack), and provides both an evidence-based and experience-based guide to multidisciplinary ALS care. The book will begin with a brief review of current concepts of ALS including diagnostic criteria, genetic and sporadic subty.

Federal Benefits for Veterans, Dependents, and Survivors

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1510744266
Total Pages : 113 pages
Book Rating : 4.5/5 (17 download)

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Book Synopsis Federal Benefits for Veterans, Dependents, and Survivors by : The US Department of Veterans Affairs

Download or read book Federal Benefits for Veterans, Dependents, and Survivors written by The US Department of Veterans Affairs and published by Simon and Schuster. This book was released on 2020-11-24 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: An official, up-to-date government manual that covers everything from VA life insurance to survivor benefits. Veterans of the United States armed forces may be eligible for a broad range of benefits and services provided by the US Department of Veterans Affairs (VA). If you’re looking for information on these benefits and services, look no further than the newest edition of Federal Benefits for Veterans, Dependents, and Survivors. The VA operates the nation’s largest health-care system, with more than 1,700 care sites available across the country. These sites include hospitals, community clinics, readjustment counseling centers, and more. In this book, those who have honorably served in the active military, naval, or air service will learn about the services offered at these sites, basic eligibility for health care, and more. Helpful topics described in depth throughout these pages for veterans, their dependents, and their survivors include: Vocational rehabilitation and employment VA pensions Home loan guaranty Burial and memorial benefits Transition assistance Dependents and survivors health care and benefits Military medals and records And more

The Behavioral Neurology of White Matter

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199938490
Total Pages : 442 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Behavioral Neurology of White Matter by : Christopher Filley

Download or read book The Behavioral Neurology of White Matter written by Christopher Filley and published by Oxford University Press. This book was released on 2012-05-18 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral neurology is founded on lesions of cortical gray matter, but recently the contributions of cerebral white matter to cognitive and emotional dysfunction have also attracted attention. The Behavioral Neurology of White Matter surveys this broad and fascinating field from a clinical perspective. Stimulated by recent improvements in neuroimaging, white matter has been carefully studied, and its role in the operations of cognition and emotion clarified by correlations with clinical observations. The relevance of normal and abnormal white matter to behavioral neurology is apparent in every context where this question has been examined: in development, aging, and in a host of diseases, intoxications, and injuries. Since the first edition of this book in 2001, steady advances have been made in understanding the neurobiology of white matter and its clinical significance; this edition provides a comprehensive update on this rapidly expanding field. Every chapter has been extensively rewritten, including a comprehensive revision of the account of the neuropsychiatry of white matter, a particularly challenging area. The syndrome of white matter dementia is discussed in detail, and its refinement with new information is considered along with the proposal of mild cognitive dysfunction as a precursor syndrome in many clinical settings. In addition, two new chapters have been added, one on the emerging area of white matter changes associated with neurodegenerative disorders such Alzheimer's Disease, and another on neurologic aspects of white matter including intriguing new information on white matter plasticity. A unifying theme is the concept of connectivity, as it is clear the white matter forms an essential component of the widespread distributed neural networks by which cognition and emotion are organized. In addition to the microconnectivity within gray matter that subserves information processing, the macroconnectivity of white matter enables information transfer - both are critical for the functions of the human mind.

Gulf War and Health

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Author :
Publisher : National Academies Press
ISBN 13 : 0309278058
Total Pages : 243 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Gulf War and Health by : Institute of Medicine

Download or read book Gulf War and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2013-04-04 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic multisymptom illness (CMI) is a serious condition that imposes an enormous burden of suffering on our nation's veterans. Veterans who have CMI often have physical symptoms (such as fatigue, joint and muscle pain, and gastrointestinal symptoms) and cognitive symptoms (such as memory difficulties). For the purposes of this report, the committee defined CMI as the presence of a spectrum of chronic symptoms experienced for 6 months or longer in at least two of six categories-fatigue, mood, and cognition, musculoskeletal, gastrointestinal, respiratory, and neurologic-that may overlap with but are not fully captured by known syndromes (such as CFS, fibromyalgia, and IBS) or other diagnoses. Despite considerable efforts by researchers in the United States and elsewhere, there is no consensus among physicians, researchers, and others as to the cause of CMI. There is a growing belief that no specific causal factor or agent will be identified. Many thousands of Gulf War veterans1 who have CMI live with sometimes debilitating symptoms and seek an effective way to manage their symptoms. Estimates of the numbers of 1991 Gulf War veterans who have CMI range from 175,000 to 250,000 (about 25-35% of the 1991 Gulf War veteran population), and there is evidence that CMI in 1991 Gulf War veterans may not resolve over time. Preliminary data suggest that CMI is occurring in veterans of the Iraq and Afghanistan wars as well. In addition to summarizing the available scientific and medical literature regarding the best treatments for chronic multisymptom illness among Gulf War veterans, Gulf War and Health: Volume 9: Treatment for Chronic Multisymptom Illness recommends how best to disseminate this information throughout the VA to improve the care and benefits provided to veterans, recommends additional scientific studies and research initiatives to resolve areas of continuing scientific uncertainty and recommends such legislative or administrative action as the IOM deems appropriate in light of the results of its review.