Occupational Exposure to Benzene and Risk of Cancer

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ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.:/5 (911 download)

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Download or read book Occupational Exposure to Benzene and Risk of Cancer written by and published by . This book was released on 2010 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Occupational Exposure to Benzene and Risk of Cancer

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (69 download)

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Book Synopsis Occupational Exposure to Benzene and Risk of Cancer by :

Download or read book Occupational Exposure to Benzene and Risk of Cancer written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis assessed the risk of cancer in relation to exposure from benzene at work. The thesis is in three major sections. The first section consisted of a systematic review and meta-analysis to assess the risk of leukemia from occupational exposure to benzene. The systematic review confirmed leukemia to be important in relation to benzene exposure; 15 selected studies yielded 16 effect estimates with an overall statistically significant effect size (relative risk) of 1.40 (95% CI, 1.23-1.57). A dose response analysis was performed and provided evidence for a strong positive trend between leukemia risks and estimated exposure to benzene. The risk of all leukemia combined increased with a dose-response pattern with a summary effect size (ES) of 1.64 (95% CI 1.13-2.39) for low (40 ppm-years), 1.90 (95% CI 1.26-2.89) for medium (40-99.9 ppm-years), and 2.62 (95% CI 1.57-4.39) for high exposure (100 ppm-years). The risk of AML also increased from low (ES 1.94, 95% CI 0.95-3.95), medium (ES 2.32, 95% CI 0.91-5.94) to high exposure category (ES 3.20, 95% CI 1.09-9.45), but the trend was not statistically significant. The second section used the same method to assess other cancer risks by conducting a systematic review and further meta-analysis. The most common other cancer sites for which a possible occupational involvement from benzene has been suggested were lung, bladder, melanoma, stomach and kidney cancer. Consequently, a systematic review and meta-analysis was performed on each of these cancer sites. The results obtained did not show any clear evidence of risk for lung cancer (ES 0.99, 95% CI 0.96-1.03), bladder cancer (ES 1.00, 95% CI 0.96-1.03), or stomach cancer (ES 0.96, 95% CI 0.90-1.03). However increased risks were shown for melanoma (ES 1.25, 95% CI 1.09-1.44) and kidney cancer (ES 1.14, 95% CI 1.04-1.25). The systematic review and meta-analysis for melanoma was based on 7 available studies reporting 8 cohorts. It was not possible to conclude that benzen.

In Search of Safety

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Publisher : Harvard University Press
ISBN 13 : 9780674446366
Total Pages : 288 pages
Book Rating : 4.4/5 (463 download)

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Book Synopsis In Search of Safety by : John D. Graham

Download or read book In Search of Safety written by John D. Graham and published by Harvard University Press. This book was released on 1991-04 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collaborative effort in which the three authors address the controversies that arise in the regulation of chemicals that are known or suspected to cause cancer. Annotation copyrighted by Book News, Inc., Portland, OR

Paediatric Haematology and Oncology

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Publisher : Oxford University Press, USA
ISBN 13 : 0199299676
Total Pages : 624 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Paediatric Haematology and Oncology by : Simon Bailey

Download or read book Paediatric Haematology and Oncology written by Simon Bailey and published by Oxford University Press, USA. This book was released on 2010 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: While survival rates for children with cancer have increased in recent times, the increased use of more aggressive therapies has brought with it significant adverse effects. Therefore, the aim of pediatric oncologists has become to achieve "cure at least cost" by the appropriate reduction of the intensity and/or duration of treatment in carefully identified good prognosis patients. By comprehensively covering these issues, this handbook aims to provide residents in pediatric hematology and oncology, as well as staff in related medical or other healthcare disciplines, with an easily accessible source of information about the basic principles of childhood cancer and leukemia, as well as much of the more detailed specialist knowledge required to care for children with these conditions. Divided into sections to allow quick access to the necessary information, the handbook covers general principles of diagnosis and treatment, short and long term care, and oncological emergencies before moving on to chapters on specific disease. Normal values and useful websites are also included for reference.

WHO Guidelines for Indoor Air Quality

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis WHO Guidelines for Indoor Air Quality by :

Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Cancer prevention research summary

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Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Cancer prevention research summary by :

Download or read book Cancer prevention research summary written by and published by . This book was released on 1985 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NIOSH Revised Recommendation for an Occupational Exposure Standard for Benzene

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Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis NIOSH Revised Recommendation for an Occupational Exposure Standard for Benzene by : National Institute for Occupational Safety and Health

Download or read book NIOSH Revised Recommendation for an Occupational Exposure Standard for Benzene written by National Institute for Occupational Safety and Health and published by . This book was released on 1979 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

How Tobacco Smoke Causes Disease

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ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Some industrial chemicals and dyestuffs : this publication represents the views and expert opinions of an IARC working group on the evaluation of the carcinogenic risk of chemicals to humans which met in Lyon, 13-20 October 1981

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Publisher :
ISBN 13 : 9789283212294
Total Pages : 0 pages
Book Rating : 4.2/5 (122 download)

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Book Synopsis Some industrial chemicals and dyestuffs : this publication represents the views and expert opinions of an IARC working group on the evaluation of the carcinogenic risk of chemicals to humans which met in Lyon, 13-20 October 1981 by :

Download or read book Some industrial chemicals and dyestuffs : this publication represents the views and expert opinions of an IARC working group on the evaluation of the carcinogenic risk of chemicals to humans which met in Lyon, 13-20 October 1981 written by and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Health Effects of Gasoline

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Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Health Effects of Gasoline by :

Download or read book Health Effects of Gasoline written by and published by . This book was released on 1993 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Profile for Benzene

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Publisher :
ISBN 13 :
Total Pages : 190 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Benzene by : Oak Ridge National Laboratory

Download or read book Toxicological Profile for Benzene written by Oak Ridge National Laboratory and published by . This book was released on 1989 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Improving the Biological Basis for Carcinogen Risk Assessment

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Publisher :
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.:/5 (34 download)

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Book Synopsis Improving the Biological Basis for Carcinogen Risk Assessment by : Elinor Wynne Fanning

Download or read book Improving the Biological Basis for Carcinogen Risk Assessment written by Elinor Wynne Fanning and published by . This book was released on 1998 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterans and Agent Orange

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Publisher : National Academies Press
ISBN 13 : 0309477166
Total Pages : 739 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Veterans and Agent Orange by : National Academies of Sciences, Engineering, and Medicine

Download or read book Veterans and Agent Orange written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-20 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.

Toxicological profile for benzene

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Publisher :
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Toxicological profile for benzene by :

Download or read book Toxicological profile for benzene written by and published by . This book was released on 2007 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Solvents

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Publisher : ChemTec Publishing
ISBN 13 : 1895198240
Total Pages : 1446 pages
Book Rating : 4.8/5 (951 download)

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Book Synopsis Handbook of Solvents by : George Wypych

Download or read book Handbook of Solvents written by George Wypych and published by ChemTec Publishing. This book was released on 2001 with total page 1446 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, extensive textual analysis of the principles of solvent selection and use, the handbook is intended to help formulators select ideal solvents, safety coordinators to protect workers, and legislators and inspectors to define and implement technically correct public safeguards for use, handling, and disposal.

Health Effects of Occupational Exposure to Asphalt

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Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Health Effects of Occupational Exposure to Asphalt by : Mary Ann Stromberg Butler

Download or read book Health Effects of Occupational Exposure to Asphalt written by Mary Ann Stromberg Butler and published by . This book was released on 2001 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: An evaluation of the health effects and other relevant data since pub. of the 1977 NIOSH "Criteria for a Recommended Standard: Occupational Exposure to Asphalt Fumes." Includes an assessment of chemistry, health, and exposure data from studies in animals and humans exposed to raw asphalt, paving and roofing asphalt fume condensates, and asphalt-based paints. Will serve as to identify future research to reduce occupational exposures to asphalt. Chapters: no. of workers potentially exposed; physical and chemical properties; exposure; human health effects; experimental studies; research needs; uses and applications; summary of occupational exposure data; and respirators.

Carcinogenicity and Toxicity of Benzene

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Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis Carcinogenicity and Toxicity of Benzene by : Myron A. Mehlman

Download or read book Carcinogenicity and Toxicity of Benzene written by Myron A. Mehlman and published by . This book was released on 1983 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: