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Nuclear Organization And Function
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Book Synopsis Nuclear Organization and Function by : Terri Grodzicker
Download or read book Nuclear Organization and Function written by Terri Grodzicker and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 75th Cold Spring Harbor Symposium volume reviews the latest advances in research into nuclear structure, the organization of the genome within the nucleus, and spatiotemporal coordination of nuclear processes.
Book Synopsis Nuclear Structure and Function by : Miguel Berrios
Download or read book Nuclear Structure and Function written by Miguel Berrios and published by Academic Press. This book was released on 1998 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nuclear Architecture and Dynamics by : Christophe Lavelle
Download or read book Nuclear Architecture and Dynamics written by Christophe Lavelle and published by Academic Press. This book was released on 2017-10-27 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds
Download or read book Nuclear Matrix written by Ronald Berezney and published by Elsevier. This book was released on 1995 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the nuclear matrix has grown enormously since Bereney and Coffey first reported its isolation and initial characterization in 1974. Since then, more than 1000 papers have been published on the subject by numerous workers around the world. This is the first book devoted to reviewing the major developments in this growing field. Key Features * The chapters cover a variety of topics, including: * Isolation of the nuclear matrix * Nuclear structure morphology in situ * Structural domains of the nuclear matrix and its components * Biochemistry and molecular biology of the matrix proteins and associated DNA and RNA * Functional properties associated with the nuclear matrix * DNA replication * Transcription * RNA splicing * Transcription regulation * Intranuclear and nucleocytoplasmic transport and targeting * Cell cycle regulation
Book Synopsis Nuclear Structure and Gene Expression by : R. Curtis Bird
Download or read book Nuclear Structure and Gene Expression written by R. Curtis Bird and published by Elsevier. This book was released on 1996-11-28 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology. * Mechanisms of interaction between nuclear structure and genes * Gene expression regulation by elements of the nuclear matrix * How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Book Synopsis Aspects of Nuclear Structure and Function by : K Leon
Download or read book Aspects of Nuclear Structure and Function written by K Leon and published by Elsevier. This book was released on 1974-01-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aspects of Nuclear Structure and Function deals with various aspects of nuclear structure and function and covers topics ranging from the ultrastructure of the female gamete to the structure, biochemistry, and functions of the nuclear envelope. Banding patterns in chromosomes, histones and nonhistone proteins, and the transfer of genetic information in polytene cells are also discussed. This book is comprised of six chapters and begins by presenting a comparative view of some aspects of the ultrastructure of the vegetative (growth) aspects of oogenesis, with emphasis on microtubules, intercellular bridges of differentiating oocytes, and vitellogenesis as well as accessory structures of the egg envelope. The following chapters explore the structure, biochemistry, and functions of the nuclear envelope; banding patterns in chromosomes; chromosomal proteins (histones and nonhistone proteins); transfer of genetic information in polytene cells; and the intracellular biology of DNA polymerases in eukaryotic cells, their association with the nucleus, and how this association changes during the mitotic cell cycle. The relationship between eukaryotic DNA polymerases and DNA replication is also examined. This monograph should be a valuable resource for biochemists.
Download or read book Nuclear Dynamics written by K. Nagata and published by Springer Science & Business Media. This book was released on 2007-12-03 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.
Book Synopsis Nuclear Organization & Function by : Terri Grodzicker
Download or read book Nuclear Organization & Function written by Terri Grodzicker and published by . This book was released on 2010 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nuclear Pore Complexes in Genome Organization, Function and Maintenance by : Maximiliano D’Angelo
Download or read book Nuclear Pore Complexes in Genome Organization, Function and Maintenance written by Maximiliano D’Angelo and published by Springer. This book was released on 2018-02-02 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome.
Book Synopsis Functional Organization of The Nucleus by :
Download or read book Functional Organization of The Nucleus written by and published by Academic Press. This book was released on 1992-02-03 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Organization of The Nucleus
Book Synopsis Genome Organization And Function In The Cell Nucleus by : Karsten Rippe
Download or read book Genome Organization And Function In The Cell Nucleus written by Karsten Rippe and published by John Wiley & Sons. This book was released on 2012-01-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
Book Synopsis Epigenetics, Nuclear Organization & Gene Function by : John C. Lucchesi
Download or read book Epigenetics, Nuclear Organization & Gene Function written by John C. Lucchesi and published by Oxford University Press. This book was released on 2018-12-19 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.
Book Synopsis Nuclear Organization in Development and Disease by : Derek J. Chadwick
Download or read book Nuclear Organization in Development and Disease written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2006-02-08 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include: How nuclear structure and location within a nucleus affect gene expression Chromatin organization and cell differentiation The nature of the interactions between the nuclear envelope and the cytoskeleton The extent to which the cytoskeleton mediates communication between the cell membrane and nucleus in regulating gene expression and whether disruption of such communication might underlie the disease processes It is hoped that a better understanding of the mechanisms leading to disease pathogenesis may ultimately lead to more rational and appropriate treatments.
Book Synopsis The Functional Nucleus by : David P. Bazett-Jones
Download or read book The Functional Nucleus written by David P. Bazett-Jones and published by Springer. This book was released on 2016-10-17 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Book Synopsis The Cell Nucleus V1 by : Harris Busch
Download or read book The Cell Nucleus V1 written by Harris Busch and published by Elsevier. This book was released on 2012-12-02 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cell Nucleus, Volume I reports the basic concepts of cell nucleus, including nuclear structure, the interaction between the nucleus and cytoplasm, and the chromatin. This volume first describes the nucleus’ morphological structures and relates these structures to its functions. It then discusses nuclear organization in plant cells; morphology and biochemistry of the slime mold nucleus; and structure, function, and properties of nuclear envelope. In addition, it addresses the molecular movements between nucleus and cytoplasm against a concentration gradient, presents experiments with animal cell heterokaryons, and explains the genome in specialized cells. It also explores the organization of the chromatin fiber; the human chromosome structure before and after banding; and the ultrastructure and function of heterochromatin and euchromatin.
Download or read book The Nucleolus written by Mark O. J. Olson and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
