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Nuclear Medicine And Immunology
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Book Synopsis Nuclear Medicine and Immunology by : Sara Harsini
Download or read book Nuclear Medicine and Immunology written by Sara Harsini and published by Springer Nature. This book was released on 2021-11-24 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the close connection between immunology and nuclear medicine, which has led to radioimmunoimaging and radioimmunotherapy (RIT). Molecular imaging with positron emission tomography (PET) and single-photon emission computed tomography (SPECT) is increasingly being used to diagnose, characterize, and monitor disease activity in the context of inflammatory disorders of known and unknown etiology, such as sarcoidosis, atherosclerosis, vasculitis, inflammatory bowel disease, rheumatoid arthritis, and degenerative joint disease. The first chapters discuss the various radiopharmaceutical agents and radiolabeled preparations that have been employed in inflammation imaging. Of these, FDG-PET imaging has been shown to have the great value in the detection of inflammation and has become the centerpiece of several initiatives over the last several years. This very powerful technique will play an increasingly important role in the management of patients with inflammatory conditions in the future. The book also explores the growing role of nuclear medicine and molecular imaging in the diagnosis and treatment of cancer. The rapid pace of change has been fueled by advances in our understanding of tumor biology, on the one hand, and the development of specifically targeted medical therapies, diagnostic agents, and radiotherapies, on the other. Written by leading international experts in the field, this book is an invaluable tool for nuclear medicine physicians, radiologists, oncologists, and immunologists.
Book Synopsis Atlas of Response to Immunotherapy by : Egesta Lopci
Download or read book Atlas of Response to Immunotherapy written by Egesta Lopci and published by Springer Nature. This book was released on 2019-11-14 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with reliable tools assessing response to treatment. A series of disease-oriented chapters will present the imaging findings during immunotherapy in the major oncological settings, with helpful comparison of functional (PET/CT) and morphological (CT/MRI) patterns of response in individual cases. To complete the atlas, a dedicated chapter will focus on major pitfalls and immune-related adverse events (irAEs) affecting image interpretation during the course of immunotherapy. The concluding chapter will lastly examine the available data and potential developments of immuno-PET, which is considered as the novel frontier of research in this oncological scenario. The atlas will be of high value for radiologists and nuclear medicine specialists at all levels of experience.
Book Synopsis Radionuclide Imaging of Infection and Inflammation by : Elena Lazzeri
Download or read book Radionuclide Imaging of Infection and Inflammation written by Elena Lazzeri and published by Springer Nature. This book was released on 2021-01-23 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas explores the latest advances in radionuclide imaging in the field of inflammatory diseases and infections, which now typically includes multimodality fusion imaging (e.g. in SPECT/CT and in PET/CT). In addition to describing the pathophysiologic and molecular mechanisms on which the radionuclide imaging of infection/inflammation is based, the clinical relevance and impact of such procedures are demonstrated in a collection of richly illustrated teaching cases, which describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Special emphasis is placed on using tomographic multimodality imaging to increase both the sensitivity and specificity of radionuclide imaging. The aim of the second edition of this book is to update the first (published in 2013) by reflecting the changes in this rapidly evolving field. Particular attention is paid to the latest advances in the radionuclide imaging of infection and inflammation, including the expanding role of hybrid imaging with [18F]FDG PET/CT SPECT/CT, without neglecting new radiotracers proposed for the imaging of infection/inflammation. Written by respected experts in the field, the book will be an invaluable tool for residents in nuclear medicine, as well as for other specialists.
Book Synopsis Nuclear Medicine in Infectious Diseases by : Alberto Signore
Download or read book Nuclear Medicine in Infectious Diseases written by Alberto Signore and published by Springer Nature. This book was released on 2019-10-15 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as a reference manual that is exceptional in systematically discussing every aspect of nuclear medicine imaging of infections, with careful explanation of the most up-to-date concepts and recent guidelines on diagnostic flowcharts as shared between the EANM, ESR, ESNR, ESCMID, ESC, EACVI, ECCO, ESGAR and EBJIS. It is truly comprehensive, describing all methods, all acquisition parameters, and all interpretation criteria in all infectious diseases. The early chapters discuss currently available radiopharmaceuticals and nuclear medicine imaging technologies, including the hybrid modalities SPECT/CT, PET/CT, and PET/MRI. The remainder of the book is devoted to the nuclear medicine imaging of infections at different body sites as well as fever of unknown origin, fungal infections, and tuberculosis and AIDS-associated infections. Infections represent a real emergency globally, and early diagnosis and treatment follow-up will continue to pose huge challenges. In this context, Nuclear Medicine in Infectious Diseases will be a superb asset for nuclear medicine and infectious disease specialists and other clinicians everywhere.
Book Synopsis Nuclear Medicine by : Richard Zimmermann
Download or read book Nuclear Medicine written by Richard Zimmermann and published by EDP Sciences. This book was released on 2019-03-07 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine is a growing specialized medical field in which radiopharmaceuticals, i.e. drugs associated to radioactivity, are used for diagnostic or therapeutic purposes. Since 1942, nuclear medicine has progressed in such a way that it became a major diagnostic tool in hospitals. The past ten years have seen the introduction of major technical breakthroughs which will considerably modify the landscape of cancer treatment. Once injected to the patient, the radiopharmaceutical drug aims at the tumour cell – including metastases – selectively, settles there, and emits radiation. Depending on the radiation type, the drug will either help identify the cells or destroy them. Applications are not limited to oncology; indeed, nuclear medicine has found interesting applications in cardiology and neurology as well. The new millennium saw the introduction of the Hybrid imaging technology PET/CT which combines the Positron Emission Tomography (PET) modality with conventional high quality x-ray imaging. It took another two years until PET could be combined with Magnetic Resonance Imaging (MRI) in the hybrid equipment PET/MR. New tracers (drugs for diagnosis) also came on the market with different diseases as targets, such as prostate cancer, neuroendocrine tumours, or Alzheimer’s disease. But the recent introduction of radiotherapeutics in the treatment of cancer has brought major changes on the market, for they can be much more powerful and specific than chemotherapeutics or external radiation therapy. Combining radiodiagnostics to select positive responders to a treatment with efficient radiotherapeutics opens a highway for the development of theranostics, another word for personalized medicine. This scientific book aims to introduce nuclear medicine to a larger audience, pointing out, among other things, the difficulties met by both physicians and patients when trying to access new technologies. This second edition shows how much progress has been made over the past ten years since the original book was published, and how much can be expected for patients within the next few years.
Book Synopsis Radioiodination: Theory, Practice, and Biomedical Applications by : Mrinal K. Dewanjee
Download or read book Radioiodination: Theory, Practice, and Biomedical Applications written by Mrinal K. Dewanjee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Download or read book Advances in Immunology written by and published by Academic Press. This book was released on 2016-05-25 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contains contributions from leading authorities Includes a wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities Informs and updates on all the latest developments in the field of immunology
Book Synopsis Nuclear Medicine in the Context of Personalized Medicine by : Françoise Kraeber-Bodéré
Download or read book Nuclear Medicine in the Context of Personalized Medicine written by Françoise Kraeber-Bodéré and published by Frontiers Media SA. This book was released on 2020-07-14 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Book Synopsis Nuclear Medicine Therapy by : Cumali Aktolun
Download or read book Nuclear Medicine Therapy written by Cumali Aktolun and published by Springer Science & Business Media. This book was released on 2012-08-31 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.
Book Synopsis Nuclear Medicine in the Management of Inflammatory and Infectious Diseases by : Alberto Signore
Download or read book Nuclear Medicine in the Management of Inflammatory and Infectious Diseases written by Alberto Signore and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: As chairman of the European Association of Nuclear Medi cine (EANM) 2001 annual meeting, I tried to reach two goals: a "universal nuclear medicine" congress where all people could speak and learn using the same language, and a full exploration of the possibility of making a diagnosis through global imaging. I am personally convinced that nuclear med icine techniques in the detection of infection and inflamma tion are essential, and in the near future their role and clinical impact will be impressive. As stated during the meeting, this topic will be one of the major and expanding fields of interest for nuclear medicine. During the post-congress meetings organized in Capri by Alberto Signore and Mauro Liberatore for each topic, there was a leading expert for the clinical, radiological and nuclear medicine aspects. This interaction was crucial for the quality of the discussion and the definition of flow charts that will be useful for all the medical community. These meetings, where for each topic there is full coverage of all the aspects of imaging, are, in my opinion, the most fruitful and useful for the progression and diffusion of nu clear medicine procedures. May 2002 Prof. Marco Salvatore Chairman of the EANM Congress 2001 Some 35 years ago, a French singer sold millions of records with a song, trying to tell the world "Capri c'est fini" - Capri is over.
Book Synopsis Nuclear Medicine: The Essentials by : Hossein Jadvar
Download or read book Nuclear Medicine: The Essentials written by Hossein Jadvar and published by Lippincott Williams & Wilkins. This book was released on 2021-09-14 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for residents and fellows to use during rotations, or as a quick review for practicing radiologists and nuclear medicine physicians, Nuclear Medicine: The Essentials is a complete, concise overview of the most important knowledge in this challenging and evolving field. Each chapter begins with learning objectives and ends with board-style questions that help you focus your learning. A self-assessment examination in print and additional self-assessment material online test your mastery of the content and prepare you for exams.
Book Synopsis Frontiers in Nuclear Medicine by : W. Horst
Download or read book Frontiers in Nuclear Medicine written by W. Horst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Zurich at the 7th International Annual Meeting of the Society of Nuclear Hedicine in Europe, held in 1969, a group of young scientists from eleven countries dedicated some papers to the memory of Georg von Hevesy. The papers were published in a book entitled "Frontiers of Nuclear Medicine" (Springer-verlag Berlin, Heidelberg, New York). On the occasion of the Second International World Congress of Nuclear Medicine and Biology held in 1978 in Washington D.C., under the presidency of Henry N.Wagner,Jr., a group of young scientists again dedicated important papers from the Congress to the memory of Georg von Hevesy. This book consists of these papers, which present new results in the field of Nuclear Medicine reported by physicians, physicists, chemists, engineers, and computer scientists. The Georg von Hevesy Foundation of Nuclear Medicine in Zurich, Switzerland together with the president of the Second World Congress of Nuclear Medicine, Henry N.Wagner,Jr., have been the major forces in arranging publication of this book. The Georg von Hevesy Foundation is sponsoring the Hevesy Prize for Nuclear Medicine, the Hevesy Medal, and the Hevesy Memorial Lecture.
Book Synopsis A Concise Guide to Nuclear Medicine by : Abdelhamid H. Elgazzar
Download or read book A Concise Guide to Nuclear Medicine written by Abdelhamid H. Elgazzar and published by Springer Nature. This book was released on 2019-08-29 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in an extensively revised second edition, summarizes the basic principles of nuclear medicine and describes the clinical applications of commonly used nuclear medicine procedures and techniques. Readers will find clear explanation of clinical indications, the pathophysiological basis of functional procedures, and the complementary role of nuclear medicine and molecular imaging in relation to diagnostic radiology. Throughout, emphasis is placed on the added diagnostic value offered by the new hybrid imaging modalities. The various therapeutic applications of nuclear medicine are also discussed. Compared with the first edition, technical details have been significantly simplified. The book will be an ideal introduction to nuclear medicine for medical students and will serve as an excellent quick reference for referring physicians, enabling them to utilize this modern medical specialty more efficiently.
Book Synopsis The Pathophysiologic Basis of Nuclear Medicine by : Abdelhamid H. Elgazzar
Download or read book The Pathophysiologic Basis of Nuclear Medicine written by Abdelhamid H. Elgazzar and published by Springer. This book was released on 2001-02-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The various patterns of accumulation of radiotracers are related to specific pathophysiologic changes - the volume takes this principle as a starting point. The book provides a new approach to understanding diagnostic and therapeutic nuclear medicine by linking the pathophysiologic changes of relevant disease processes to scintigraphy. This permits accurate identification of various imaging patterns with more meaningful interpretation. Through the use of illustrations, charts and tables, this link is presented simply and clearly. The book is intended not only for nuclear physicians and technologists, but also for the referring physicians, who will understand the effective utilization of nuclear medicine and its impact on patient management.
Book Synopsis Handbook of Nuclear Medicine and Molecular Imaging by : E. Edmund Kim
Download or read book Handbook of Nuclear Medicine and Molecular Imaging written by E. Edmund Kim and published by World Scientific. This book was released on 2012 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook will provide updated information on nuclear medicine and molecular imaging techniques as well as its clinical applications, including radionuclide therapy, to trainees and practitioners of nuclear medicine, radiology and general medicine. Updated information on nuclear medicine and molecular imaging are vitally important and useful to both trainees and existing practitioners. Imaging techniques and agents are advancing and changing so rapidly that concise and pertinent information are absolutely necessary and helpful. It is hoped that this handbook will help readers be better equipped for the utilization of new imaging methods and treatments using radiopharmaceuticals.
Book Synopsis Clinical Use of Antibodies by : Richard P. Baum
Download or read book Clinical Use of Antibodies written by Richard P. Baum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the "Ehrlich Era" (first steps in immunology "Magic Bullet" concept) and the "Behring Era" (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124.
