Technical Report on Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)

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Publisher : DIANE Publishing
ISBN 13 : 1437914551
Total Pages : 302 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) by : R. L. Melnick

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) written by R. L. Melnick and published by DIANE Publishing. This book was released on 2009-09 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bromochloroacetic acid is a water disinfection by-product. Bromochloroacetic acid was nominated for toxicity and carcinogenicity studies in rats and mice because of widespread human exposure and because a related dihaloacetate, dichloroacetate, was found to be carcinogenic to the liver of rats and mice. Drinking water was selected as the route of exposure to mimic human exposure to this chemical. Male and female F344/N rats and B6C3F1 mice were exposed to bromochloroacetic acid (greater than 95% pure) in drinking water for 2 weeks, 3 months, or 2 years. Genetic toxicology studies were conducted in ¿Salmonella typhimurium,¿ ¿Escherichia coli,¿ and peripheral blood erythrocytes of exposed mice. Illustrations.

NTP GMM.

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ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis NTP GMM. by :

Download or read book NTP GMM. written by and published by . This book was released on 2005 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetically Modified Model Report on Toxicology and Carcinogeneticity Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tb. ACV Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenecity Studies of Dichloroacetic Acid in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water Studies)

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Publisher :
ISBN 13 : 9781422315200
Total Pages : 167 pages
Book Rating : 4.3/5 (152 download)

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Book Synopsis Genetically Modified Model Report on Toxicology and Carcinogeneticity Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tb. ACV Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenecity Studies of Dichloroacetic Acid in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water Studies) by : G. A. Boorman

Download or read book Genetically Modified Model Report on Toxicology and Carcinogeneticity Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tb. ACV Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenecity Studies of Dichloroacetic Acid in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water Studies) written by G. A. Boorman and published by . This book was released on 2007-08-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dichloroacetic acid was nominated for study by the EPA because of its widespread occurrence in drinking water as a byproduct of water disinfection using chlorination. It was also nominated because dicholoroacetic acid is the most studied representative of the class of haloacetic acids & has been shown to cause liver tumors in both rats & mice. Haloacetic acids are second only to trihalomethanes as a family of disinfection byproducts found in many drinking water supplies. Dichloroacetic acid is one of several disinfection byproducts being evaluated to determine whether genetically modified mouse models can serve as a more rapid & cost-effective means of evaluating & ranking potential hazards of disinfection byproducts. Illustrations.

Physical and Thermodynamic Properties of Pure Chemicals

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (831 download)

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Download or read book Physical and Thermodynamic Properties of Pure Chemicals written by and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens

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Publisher : William Andrew
ISBN 13 : 0815519044
Total Pages : 2888 pages
Book Rating : 4.8/5 (155 download)

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Book Synopsis Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens by : Richard P. Pohanish

Download or read book Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens written by Richard P. Pohanish and published by William Andrew. This book was released on 2008-01-10 with total page 2888 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than a quarter century, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens has proven to be among the most reliable, easy-to-use and essential reference works on hazardous materials. Sittig's 5th Edition remains the lone comprehensive work providing a vast array of critical information on the 2,100 most heavily used, transported, and regulated chemical substances of both occupational and environmental concern.Information is the most vital resource anyone can have when dealing with potential hazardous substance accidents or acts of terror. Sittig's provides extensive data for each of the 2,100 chemicals in a uniform format, enabling fast and accurate decisions in any situation. The chemicals are presented alphabetically and classified as a carcinogen, hazardous substance, hazardous waste, or toxic pollutant. This new edition contains extensively expanded information in all 28 fields for each chemical (see table of contents) and has been updated to keep pace with world events. Chemicals classified as WMD have been included in the new edition as has more information frequently queried by first responders and frontline industrial safety personnel.*Includes and references European chemical identifiers and regulations.*The only single source reference that provides such in-depth information for each chemical.*The two volume set is designed for fast and accurate decision making in any situation.

Handling Chemical Carcinogens in the Laboratory, Problems of Safety

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ISBN 13 :
Total Pages : 50 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Handling Chemical Carcinogens in the Laboratory, Problems of Safety by : R. Montesano

Download or read book Handling Chemical Carcinogens in the Laboratory, Problems of Safety written by R. Montesano and published by . This book was released on 1979 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Technologies for Upgrading Existing Or Designing New Drinking Water Treatment Facilities

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ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Technologies for Upgrading Existing Or Designing New Drinking Water Treatment Facilities by :

Download or read book Technologies for Upgrading Existing Or Designing New Drinking Water Treatment Facilities written by and published by . This book was released on 1990 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exploring QSAR

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ISBN 13 : 9780841229877
Total Pages : 348 pages
Book Rating : 4.2/5 (298 download)

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Book Synopsis Exploring QSAR by : Corwin H. Hansch

Download or read book Exploring QSAR written by Corwin H. Hansch and published by . This book was released on 1995 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP GMM.

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ISBN 13 :
Total Pages : 146 pages
Book Rating : 4.:/5 (9 download)

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Download or read book NTP GMM. written by and published by . This book was released on 2005 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Slow Sand Filtration

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ISBN 13 : 9789241540377
Total Pages : 0 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Slow Sand Filtration by : L. Huisman

Download or read book Slow Sand Filtration written by L. Huisman and published by . This book was released on 1974 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Water Technology

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Publisher : Wiley
ISBN 13 : 9780470236321
Total Pages : 0 pages
Book Rating : 4.2/5 (363 download)

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Book Synopsis Water Technology by : N. F. Gray

Download or read book Water Technology written by N. F. Gray and published by Wiley. This book was released on 1997-03-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nick Gray is well known for both his texts and reference works on water technology, and he now brings his research and teaching expertise to this introductory student textbook. Written as a comprehensive and accessible introduction, Water Technology introduces the key concepts of hydrobiology, water treatment and supply, and wastewater treatment. Throughout the book the environmental impacts of policy and practice are assessed. The book: covers water quality and regulation, including European and US legislation and standards explains the fundamentals of hydrobiology and aquatic ecosystems deals with water quality assessment, management and treatment includes in-depth coverage of wastewater treatment and disposal is highly illustrated and includes numerous tables to help the reader Water Technology is essential reading for the environmental science or engineering student.

Genetically Modified Model Report on Toxicology Studies of Bromodichloromethane (CAS No. 75-27-4) in Genetically Modified (FVB Tb. AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies)

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ISBN 13 : 9781422315224
Total Pages : 227 pages
Book Rating : 4.3/5 (152 download)

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Book Synopsis Genetically Modified Model Report on Toxicology Studies of Bromodichloromethane (CAS No. 75-27-4) in Genetically Modified (FVB Tb. AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies) by : G. A. Boorman

Download or read book Genetically Modified Model Report on Toxicology Studies of Bromodichloromethane (CAS No. 75-27-4) in Genetically Modified (FVB Tb. AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6. 129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies) written by G. A. Boorman and published by . This book was released on 2007-08-01 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bromodichloromethane (BD) is a by-product of the chlorination of drinking water. It is formed by the halogen substitution & oxidation reactions of chlorine & naturally occurring organic matter (e.g., humic or fluvic acids) in water containing bromide. BD was nominated to the Nat. Toxicology Program for toxicology & carcinogenecity studies. Male & female Tb.AC hemizygous mice received bromodichloromethane (at least 99% pure) by dermal application for 26 or 39 weeks, in drinking water for 26 or 42 weeks, or by gavage for 26 or 41 weeks. p53 Haploinsufficient mice received BD in drinking water for 26 or 42 weeks or by gavage for 26 or 42 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.

Selection of Representative TPH Fractions Based on Fate and Transport Considerations

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ISBN 13 : 9781884940125
Total Pages : 102 pages
Book Rating : 4.9/5 (41 download)

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Book Synopsis Selection of Representative TPH Fractions Based on Fate and Transport Considerations by : John B. Gustafson

Download or read book Selection of Representative TPH Fractions Based on Fate and Transport Considerations written by John B. Gustafson and published by . This book was released on 1997 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: