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Novel Vaccination Strategies For Induction Of Long Term Immune Memory And Protection Of Bovine Respiratory Disease
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Book Synopsis Novel Vaccination Strategies for Induction of Long-term Immune Memory and Protection of Bovine Respiratory Disease by : Saskatchewan. Agriculture Development Fund
Download or read book Novel Vaccination Strategies for Induction of Long-term Immune Memory and Protection of Bovine Respiratory Disease written by Saskatchewan. Agriculture Development Fund and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis สัมพันธภาพระหว่างบุคลิกภาพ และผลสัมฤทธิ์ของนักศึกษาระดับปริญญาตรีปีสุดท้าย มหาวิทยาลัยมหิดล by :
Download or read book สัมพันธภาพระหว่างบุคลิกภาพ และผลสัมฤทธิ์ของนักศึกษาระดับปริญญาตรีปีสุดท้าย มหาวิทยาลัยมหิดล written by and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunization Safety Review by : Institute of Medicine
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-02 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.
Book Synopsis New-generation vaccines and novel vaccinal strategies against infectious diseases of livestock, wild and companion animals by : Denis Archambault
Download or read book New-generation vaccines and novel vaccinal strategies against infectious diseases of livestock, wild and companion animals written by Denis Archambault and published by Frontiers Media SA. This book was released on 2023-08-25 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging infections, in particular those caused by viruses, are expected to rise in correlation, among other factors, with climate changes. Antibiotic resistance is another issue that will limit the therapeutic arsenal against bacterial and parasitic infections. Therefore, one must be adequately prepared to overcome and prevent current and novel infections, and vaccination remains the optimal way to fight infectious diseases in humans. This is also true for many impacting diseases of livestock and companion animals, to which there are no available vaccines. First (attenuated and inactivated) and second (subunit) generation vaccines have their limitations. To overcome this, efforts have been made in recent years to develop novel vaccine types such as virus-like particle (VLP)-, viral vector-, and DNA-based vaccines in humans and animals. The recent success in utilizing RNA technology based-vaccines to fight SARS-CoV-2 to limit the severity of clinical symptoms and mortality constitutes a promising way to develop such vaccines against animal diseases. Development of novel molecules or materials with adjuvant or immunostimulatory activity to adequately stimulate the innate immune response, and, therefore the pathogen-specific adaptative immune response, as well as the identification of suitable antigenic material that would bring broad protection against infectious agent variants are other key issues to be considered in developing safe and innovative immunization strategies.
Author :Veterinary Infectious Disease Organization Publisher :Regina : Beef Development Fund ISBN 13 : Total Pages :28 pages Book Rating :4.:/5 (563 download)
Book Synopsis Oral Vaccination of Neonatal Calves : Induction of Long Term Immunity : Final Report by : Veterinary Infectious Disease Organization
Download or read book Oral Vaccination of Neonatal Calves : Induction of Long Term Immunity : Final Report written by Veterinary Infectious Disease Organization and published by Regina : Beef Development Fund. This book was released on 1997 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mucosal Vaccines by : Hiroshi Kiyono
Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Elsevier. This book was released on 1996-10-23 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization
Book Synopsis Optimization of the Theileria Parva Antigen P67 for Use in the Novel Bovine Herpesvirus-4 Vaccine Delivery Platform by : Laura Beth Artz Williams
Download or read book Optimization of the Theileria Parva Antigen P67 for Use in the Novel Bovine Herpesvirus-4 Vaccine Delivery Platform written by Laura Beth Artz Williams and published by . This book was released on 2018 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: East Coast Fever (ECF), caused by the tick-borne protozoan parasite Theileria parva, results in significant bovine morbidity, mortality, and production losses in regions of sub-Saharan Africa. The development of a sustainable, deployable next-generation vaccine is critical to the long term control of ECF and improving the economics of the pastoral farmer. Herpesviruses as vaccine vector systems have been recently exploited due to their intrinsic ability to establish persistent infection, resulting in the provision of long-term antigen expression and antigen-specific immune responses. Bovine herpesvirus-4 (BoHV-4), a gammaherpesvirus, has inherent advantages as a vaccine platform for antigen delivery. Like other herpesviruses, BoHV-4 establishes a persistent infection, and may facilitate the long-term expression of T. parva antigens in the bovine host. BoHV-4 has shown clinical success in experimental vaccines against a variety of infectious diseases in multiple species by inducing high levels of serum-neutralizing antibodies to targeted pathogens. In this work, we provide evidence that recombinant bovine herpesvirus-4 is able to elicit robust antigen-specific neutralizing immunity following immunization of cattle via intranasal nebulization. More specifically, we show evidence that these responses can occur in the face of pre-existing BoHV-4 immunity. We also provide evidence that recombinant BoHV-4 persists in immunized cattle and that recrudescence of the virus boosts the immune response to BoHV-4-vectored antigens. Thus, BoHV-4 is considered an ideal vector for development of a next-generation vaccine against T. parva. The T. parva sporozoite surface antigen (p67) is known to generate anti-sporozoite antibody activity in cattle. Previous immunization studies have developed various forms of recombinant p67 capable of providing protection of cattle from severe ECF. However, optimization of p67 expression and p67-based immunization strategies is necessary. In this work, we describe the stable expression of full length, membrane-linked recombinant p67 in mammalian cells, which is immunogenic in cattle. The antigen expression system described here is expected to optimize p67-based immunization. The incorporation of the full-length p67 expression system developed in this study in the BoHV-4 vector system developed for cattle in this study is expected to optimize humoral antibody responses and provide clinical protection from disease in future vaccine development strategies.
Author :Committee on Health Effects Associated with Exposures During the Gulf War Publisher :National Academies Press ISBN 13 :0309171628 Total Pages :426 pages Book Rating :4.3/5 (91 download)
Book Synopsis Gulf War and Health by : Committee on Health Effects Associated with Exposures During the Gulf War
Download or read book Gulf War and Health written by Committee on Health Effects Associated with Exposures During the Gulf War and published by National Academies Press. This book was released on 2000-12-12 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The men and women who served in the Gulf War theater were potentially exposed to a wide range of biological and chemical agents. Gulf War and Health: Volume 1 assesses the scientific literature concerning the association between these agents and the adverse health effects currently experienced by a large number of veterans.
Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes
Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Book Synopsis Novel Technologies for Vaccine Development by : Igor S Lukashevich
Download or read book Novel Technologies for Vaccine Development written by Igor S Lukashevich and published by Springer. This book was released on 2014-11-13 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
Book Synopsis Fundamentals of Pharmaceutical Nanoscience by : Ijeoma F. Uchegbu
Download or read book Fundamentals of Pharmaceutical Nanoscience written by Ijeoma F. Uchegbu and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience or the science of the very small offers the pharmaceutical scientist a wealth of opportunities. By fabricating at the nanoscale, it is possible to exert unprecedented control on drug activity. This textbook will showcase a variety of nanosystems working from their design and construction to their application in the field of drug delivery. The book is intended for graduate students in drug delivery, physical and polymer chemistry, and applied pharmaceutical sciences courses that involve fundamental nanoscience. The purpose of the text is to present physicochemical and biomedical properties of synthetic polymers with an emphasis on their application in polymer therapeutics i.e., pharmaceutical nanosystems, drug delivery and biological performance. There are two main objectives of this text. The first is to provide advanced graduate students with knowledge of the principles of nanosystems and polymer science including synthesis, structure, and characterization of solution and solid state properties. The second is to describe the fundamentals of therapeutic applications of polymers in drug delivery, targeting, response modifiers as well as regulatory issues. The courses, often listed as Advanced Drug Delivery and Applied Pharmaceutics; Polymer Therapeutics; or Nanomedicine, are designed as an overview of the field specifically for graduate students in the Department of Pharmaceutical Sciences Graduate Programs. However, the course content may also be of interest for graduate students in related biomedical research programs. These courses generally include a discussion of the major principles of polymer science and fundamental concepts of application of polymers as modern therapeutics. All courses are moving away from the above mentioned course names and going by ‘pharmaceutical nanoscience or nanosystems’. This area of research and technology development has attracted tremendous attention during the last two decades and it is expected that it will continue to grow in importance. However, the area is just emerging and courses are limited but they are offered.
Book Synopsis Rinderpest and Peste des Petits Ruminants by : William P. Taylor
Download or read book Rinderpest and Peste des Petits Ruminants written by William P. Taylor and published by Elsevier. This book was released on 2005-11-15 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rinderpest and Peste des Petits Ruminants tells the story of how, by the year 2010, scientists are set to globally eradicate one of the great historic plagues that has ravaged human livestock for centuries. Descriptions of the disease in Europe date back to the 4th century and it was regularly re-introduced following wars and other civil unrest until late in the 19th century. It was introduced with devastating effect into Africa towards the end of the 19th century and is now widespread across sub-Saharan Africa, the Middle East and Southern Asia. Its causative agent, rinderpest virus, a morbillivirus very closely related to human measles virus, decimates the cattle population along with those of other susceptible domestic ruminants and many wildlife species wherever it is present. The history of Rinderpest including the history of vaccines and vaccination Details other Morbillaviruses Epidemiology and transmission of Rinderpest
Book Synopsis Annual Report by : Saskatchewan. Ministry of Agriculture
Download or read book Annual Report written by Saskatchewan. Ministry of Agriculture and published by . This book was released on 2007 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nanoparticulate Vaccine Delivery Systems by : Martin J. D'Souza
Download or read book Nanoparticulate Vaccine Delivery Systems written by Martin J. D'Souza and published by CRC Press. This book was released on 2015-06-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen the development of novel technologies that use nanoparticles and microparticles to deliver vaccines by the oral and microneedle-based transdermal route of administration. These new technologies enable the formulation of vaccine particles containing vaccine antigens, without loss of their biological activity during the formula
Book Synopsis Vaccines for the 21st Century by : Institute of Medicine
Download or read book Vaccines for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Book Synopsis Development of Novel Vaccines by : Alexander von Gabain
Download or read book Development of Novel Vaccines written by Alexander von Gabain and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.
Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine
Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.