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Nonhuman Primate Models In Biomedical Research State Of The Science And Future Needs
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Book Synopsis Nonhuman Primate Models in Biomedical Research: State of the Science and Future Needs by : National Academies Of Sciences Engineeri
Download or read book Nonhuman Primate Models in Biomedical Research: State of the Science and Future Needs written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2024-02-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman primates represent a small fraction of animals used in biomedical research, but they remain important research models due to their similarities to humans with respect to genetic makeup, anatomy, physiology, and behavior. Limitations in the availability of nonhuman primates have been exacerbated by the COVID-19 pandemic and recent restrictions on their exportation and transportation, impacting National Institutes of Health (NIH)-funded research necessary for both public health and national security. Additionally, there is continued interest in understanding whether and how nonanimal models can be used to answer scientific questions for which nonhuman primates are currently used. At the direction of the U.S. Congress, NIH asked the National Academies of Sciences, Engineering, and Medicine to convene an expert committee to conduct a landscape analysis of current and future use of nonhuman primates in NIH-supported biomedical research, as well as opportunities for new approach methodologies to complement or reduce reliance on nonhuman primate models. This report provides the committee findings and conclusions.
Book Synopsis Nonhuman Primates in Biomedical Research,Two Volume Set by : Christian R. Abee
Download or read book Nonhuman Primates in Biomedical Research,Two Volume Set written by Christian R. Abee and published by Academic Press. This book was released on 2012-04-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The publication emphasizes the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information
Book Synopsis Nonhuman Primate Models For Human Diseases by : W. Richard Dukelow
Download or read book Nonhuman Primate Models For Human Diseases written by W. Richard Dukelow and published by CRC Press. This book was released on 2018-02-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.
Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee
Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-03-29 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date review of the use of nonhuman primates in biomedical research, emphasising the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research.
Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee
Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-05-09 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information
Book Synopsis Nonhuman Primates and Medical Research by : Geoffrey H. Bourne
Download or read book Nonhuman Primates and Medical Research written by Geoffrey H. Bourne and published by Academic Press. This book was released on 2014-05-10 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman Primates and Medical Research focuses on the contributions of nonhuman primates to biomedical research. The selection first elaborates on monkeys and yellow fever, cell cultures, and tuberculosis and bacterial infection. Discussions focus on bacterial diseases, tuberculosis, radiobiology, antibody formation and pharmacologic studies, cell-culture media and methods, the rhesus monkey and early history of yellow fever research, and monkeys and yellow fever in the future. The text then elaborates on virus research, models for investigation in parasitology, and primates as organ donors in transplantation studies in man. The manuscript examines the importance of monkeys for the study of malignant tumors in man; use of primates in cardiovascular research; and humanlike diseases in anthropoid apes. Topics include etiology of humanlike disease in anthropoid apes, atherosclerosis, historical aspects of primate research, selection of a suitable primate, and preeclampsia. The text also ponders on primate studies and human evolution and mental retardation. The selection is a valuable reference for researchers interested in the contributions of nonhuman primates to biomedical research.
Book Synopsis The Baboon in Biomedical Research by : John L. VandeBerg
Download or read book The Baboon in Biomedical Research written by John L. VandeBerg and published by Springer Science & Business Media. This book was released on 2009-06-04 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.
Book Synopsis Challenges in Nonhuman Primate Research in the 21st Century by : Gerhard F. Weinbauer
Download or read book Challenges in Nonhuman Primate Research in the 21st Century written by Gerhard F. Weinbauer and published by Waxmann Verlag. This book was released on 2013 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: In continuation of the Covance Primate Symposium Series, the 19th Covance Primate Symposium took place in Münster on 23rd & 24th of May 2012. Altogether, 70 participants representing 43 organisations, gathered for this symposium. The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate Research in the 21st Century?. The broad participation and the lively discussions during the symposium underlined the timeliness and importance of this topic. Expert speakers covered four major topics, i.e. biosimilars development: regulatory implications, key considerations and next steps, optimizing nonhuman primate use in nonclinical safety assessment, trends in nonhuman primate developmental & reproductive toxicology (DART) and juvenile toxicity evaluation, and relevance and importance of nonhuman primate models in regulatory toxicology. The development of biosimilar has taken up speed considerably and meanwhile needs to be considered a significant factor of potential drug development, yet there are still some uncertainties und guidelines are under development. With the increased focus on biopharmaceuticals and the associated increase for using nonhuman primates being the relevant animal model, it became necessary to optimize the use of this animal model, e.g. refine study designs and animals numbers but still execute meaningful preclinical studies. It appears that significant progress has been achieved in that context. In the area of nonhuman primate DART and juvenile toxicity evaluation, recent guideline changes had a major impact on species selection, and the experimental design plus the timing of these studies within the preclinical programmes. Finally, given the increasing regulations and justficiations of using nonhuman primates as experimental models. It is paramount to understand the essential and indispensable role that nonhuman primates can play in drug safety evaluation and medical drug development.
Book Synopsis Nonhuman Primate Models in Preclinical Research by : Huifang Chen
Download or read book Nonhuman Primate Models in Preclinical Research written by Huifang Chen and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognized that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinson's disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise"--
Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee
Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-04-12 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information
Book Synopsis Nonhuman Primates in Biomedical Research by :
Download or read book Nonhuman Primates in Biomedical Research written by and published by . This book was released on 2012 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. * Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research * Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information * Includes four color images throughout.
Book Synopsis Survey of NIH-funded Investigators who Use Nonhuman Primates by :
Download or read book Survey of NIH-funded Investigators who Use Nonhuman Primates written by and published by . This book was released on 2002 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Laboratory Nonhuman Primate by : Jeffrey D. Fortman
Download or read book The Laboratory Nonhuman Primate written by Jeffrey D. Fortman and published by CRC Press. This book was released on 2001-09-27 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on over 50 years of combined experience, The Laboratory Nonhuman Primate provides a quick reference source for technicians working with non-human primates in biomedical research. It details basic information and frequently used procedures such as duties of animal husbandry, facility management, regulatory compliance, and technical procedure
Book Synopsis Nonhuman Primates in Biomedical Research. Volume 1 by : Christian R. Abee
Download or read book Nonhuman Primates in Biomedical Research. Volume 1 written by Christian R. Abee and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. * Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research * Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information * Includes four color images throughout.
Download or read book The Laboratory Primate written by and published by Elsevier. This book was released on 2005-09-19 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the Handbook of Experimental Animals series, The Laboratory Primate details the past and present use of primates in biomedical research, and the husbandry, nutritional requirements, behaviour, and breeding of each of the commonly used species. Practical information on regulatory requirements, not available in other texts, is covered. Sections on experimental models cover the major areas of biomedical research, including AIDS, cancer, neurobiology and gene therapy. Assisted reproductive technology, tissue typing, and minimum group sizes for infectious disease/vaccine studies are also included. Two-color, user-friendly format, with copious illustrations and color plates Includes detailed, well-illustrated sections on gross & microscopic anatomy, common diseases, and special procedures, including surgical techniques
Book Synopsis Nonhuman Primates in Biomedical Research by :
Download or read book Nonhuman Primates in Biomedical Research written by and published by Academic Press. This book was released on 1995-08-04 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman Primates in Biomedical Research: Biology and Management represents the most comprehensive publication of its type on nonhuman primates. It also provides basic information on the biology and management of primates for anyone responsible for the care and use of these animals. A related book on primate diseases will be published in 1996. Stresses the following major topics: Biology and medical management Reproductive physiology and breeding Nutrition Biohazards
Book Synopsis Aping Science by : Yerkes Laboratories of Primate Biology (Atlanta, Ga.).
Download or read book Aping Science written by Yerkes Laboratories of Primate Biology (Atlanta, Ga.). and published by . This book was released on 1995 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
