Nonanticoagulant Actions Of Glycosaminoglycans

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Nonanticoagulant Actions of Glycosaminoglycans

Author : B. Casu
Publisher : Springer Science & Business Media
ISBN 13 : 1461303710
Total Pages : 294 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Nonanticoagulant Actions of Glycosaminoglycans by : B. Casu

Download or read book Nonanticoagulant Actions of Glycosaminoglycans written by B. Casu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prophylaxis and treatment of thromboembolism have made one of the major impacts in medicine. Heparin has widely been used as the most effective drug during the last 50 years. However, its potential side effects have led to the search for equally effective but safer alternatives. At present, the low-molecular-weight heparins are the most promising steps in this direction. Considerable interest has been generated at the same time in exploring other gly cosaminoglycans of the nonheparin type for therapeutic use. The existence of these com pounds has been known for a long time and substantial information has been gathered on glycosaminoglycans such as heparinsulfate, dermatansulfate, and chondroitinsulfate. Many of these substances are derived from animal or plant sources, and some of them have now been synthesized. The aim of the Fourth Symposium on Glycosaminoglycan Research at Villa Vigoni in Loveno at Lake Comolltaly was to summarize the considerable new information in this field. The articles of the present volume are mainly based on a German-Italian collaboration supported by the Vigoni Program. The selected articles describe many different, nonheparin glycosaminoglycans, some of them already in clinical trials as antithrombotic agents. In particular, the interaction of glycosaminoglycans with some cellular elements of blood, especially leukocytes and platelets, are discussed. New methods for their identification and assays are described and considerable emphasis is placed on the pharmacokinetic aspects of these new compounds. Particularly, some nonanticoagulant activities of the glycosamino glycans are discussed in detail.

Cigarette Smoking and the Kidney

Author : A. Sessa
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805570643
Total Pages : 148 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Cigarette Smoking and the Kidney by : A. Sessa

Download or read book Cigarette Smoking and the Kidney written by A. Sessa and published by Karger Medical and Scientific Publishers. This book was released on 2000-01-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cigarette smoking is also a risk factor for diffuse atherosclerosis, ischemic heart disease and peripheral vascular lesions, renal microvessels being another potential target. Furthermore, the relationships of chronic cigarette smoking and nitric oxide with endothelial dysfunction and vascular disease are well proven, and the association between eNOS gene polymorphisms and vascular disease and their dependence on chronic tobacco smoking has been stressed. But although there is definite evidence that the risk of progression of acquired or genetic renal disease is higher in chronic cigarette smokers and the negative effect on patient survival in chronic dialytic treatment is well known, these issues are still neglected by clinical nephrologists and the mechanisms involved have not yet been classified.

Mapping the Progress of Alzheimer’s and Parkinson’s Disease

Author : Yoshikuni Mizuno
Publisher : Springer Science & Business Media
ISBN 13 : 9780306467639
Total Pages : 596 pages
Book Rating : 4.4/5 (676 download)

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Book Synopsis Mapping the Progress of Alzheimer’s and Parkinson’s Disease by : Yoshikuni Mizuno

Download or read book Mapping the Progress of Alzheimer’s and Parkinson’s Disease written by Yoshikuni Mizuno and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1h The 5 International Conference on the Progress in Alzheimer's Disease and Parkinson's 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a joint Congress with the 9 International Catecholamine Symposium. A total of 1258 clinicians and researchers participated in this joint congress 1h from 38 countries in the world. This book represents the proceedings of the 5 Conference on Alzheimer's and Parkinson's disease. The International Conference on the Progress in Alzheimer's and Parkinson's disease was first launched by Professor Abraham Fisher of Israel and Professor Israel Hanin of USA. The first conference was held in Eilat, Israel in 1985. The second conference was organized in Kyoto, Japan in 1989; the third one in Chicago, USA, in 1993, and the fourth one in Eilat, Israel in 1997. The International Catecholamine Symposium (ICS) is an international meeting devoted to the development of basic as well as clinical research on catecholamines. The first Catecholamine Symposium was held in Bethesda, USA in 1958. Since then this symposium has occurred every 5 years. Professor Toshiharu Nagatsu was appointed as 1h the president of the 9 International Catecholamine Symposium, which was to be held in 200 I also in Japan. Therefore, we decided to organize a joint congress of the two meetings, because there is much overlap in research between Alzheimer's disease, Parkinson's disease, and catecholamines. We thank Professor Nagatsu very much for agreeing to organizing this joint congress.

Glycoscience: Chemistry and Chemical Biology I–III

Author : Bertram O. Fraser-Reid
Publisher : Springer Science & Business Media
ISBN 13 : 3642568742
Total Pages : 2817 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Glycoscience: Chemistry and Chemical Biology I–III by : Bertram O. Fraser-Reid

Download or read book Glycoscience: Chemistry and Chemical Biology I–III written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 2817 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.

Glycosaminoglycans and Proteoglycans

Author : 978-3-03842-836-7
Publisher : MDPI
ISBN 13 : 3038428353
Total Pages : 247 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Glycosaminoglycans and Proteoglycans by : 978-3-03842-836-7

Download or read book Glycosaminoglycans and Proteoglycans written by 978-3-03842-836-7 and published by MDPI. This book was released on 2018-07-04 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Glycosaminoglycans and Proteoglycans" that was published in Pharmaceuticals

Advances in Carbohydrate Chemistry and Biochemistry

Author :
Publisher : Elsevier
ISBN 13 : 9780080522258
Total Pages : 492 pages
Book Rating : 4.5/5 (222 download)

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Book Synopsis Advances in Carbohydrate Chemistry and Biochemistry by :

Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by and published by Elsevier. This book was released on 2002-02-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists who integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

American Book Publishing Record

Author :
Publisher :
ISBN 13 :
Total Pages : 1438 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Book Publishing Record by :

Download or read book American Book Publishing Record written by and published by . This book was released on 1996-05 with total page 1438 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cumulative Book Index

Author :
Publisher :
ISBN 13 :
Total Pages : 2312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cumulative Book Index by :

Download or read book The Cumulative Book Index written by and published by . This book was released on 1997 with total page 2312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1796 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heparanase

Author : Israel Vlodavsky
Publisher : Springer Nature
ISBN 13 : 3030345211
Total Pages : 871 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Heparanase by : Israel Vlodavsky

Download or read book Heparanase written by Israel Vlodavsky and published by Springer Nature. This book was released on 2020-04-09 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized leaders in Heparanase biology, the book’s eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.

Heparin - A Century of Progress

Author : Rebecca Lever
Publisher : Springer Science & Business Media
ISBN 13 : 3642230563
Total Pages : 457 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Heparin - A Century of Progress by : Rebecca Lever

Download or read book Heparin - A Century of Progress written by Rebecca Lever and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Directory of Published Proceedings

Author :
Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Directory of Published Proceedings by :

Download or read book Directory of Published Proceedings written by and published by . This book was released on 1998 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heart Physiology and Pathophysiology

Author : Yoshihisa Kurachi
Publisher : Elsevier
ISBN 13 : 0080533884
Total Pages : 1286 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Heart Physiology and Pathophysiology by : Yoshihisa Kurachi

Download or read book Heart Physiology and Pathophysiology written by Yoshihisa Kurachi and published by Elsevier. This book was released on 2000-10-09 with total page 1286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Industrial Applications of Renewable Biomass Products

Author : Silvia Nair Goyanes
Publisher : Springer
ISBN 13 : 3319612883
Total Pages : 332 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Industrial Applications of Renewable Biomass Products by : Silvia Nair Goyanes

Download or read book Industrial Applications of Renewable Biomass Products written by Silvia Nair Goyanes and published by Springer. This book was released on 2017-08-10 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book effectively links the latest scientific advances to current technological applications of polymers, mainly focusing on biodegradable polymers obtained from biomass. The individual chapters were written by academic and industry researchers alike, introducing readers to topics that have received little attention in the literature to date. Key topics covered include polymers used in various areas such as food packaging, pharmaceuticals, energy production and the cosmetics industry, as well as the treatment of aqueous effluents.

The British National Bibliography

Author : Arthur James Wells
Publisher :
ISBN 13 :
Total Pages : 1672 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The British National Bibliography by : Arthur James Wells

Download or read book The British National Bibliography written by Arthur James Wells and published by . This book was released on 1996 with total page 1672 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemistry and Biology of Heparin and Heparan Sulfate

Author : Hari G. Garg
Publisher : Elsevier
ISBN 13 : 9780080529059
Total Pages : 792 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Chemistry and Biology of Heparin and Heparan Sulfate by : Hari G. Garg

Download or read book Chemistry and Biology of Heparin and Heparan Sulfate written by Hari G. Garg and published by Elsevier. This book was released on 2011-10-10 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. Comprehensively reviews all aspects of heparin and heparan sulfate research Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners

Hemostasis and Thrombosis

Author : Victor J. Marder
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451177690
Total Pages : 5220 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Hemostasis and Thrombosis by : Victor J. Marder

Download or read book Hemostasis and Thrombosis written by Victor J. Marder and published by Lippincott Williams & Wilkins. This book was released on 2012-12-27 with total page 5220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.