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Non Invasive Brain Stimulation In The Study And Modulation Of Metaplasticity In Neurological Disorders
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Book Synopsis Non-Invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders by : Mariagiovanna Cantone
Download or read book Non-Invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders written by Mariagiovanna Cantone and published by Frontiers Media SA. This book was released on 2021-09-03 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Innovative Technologies and Clinical Applications for Invasive and Non-Invasive Neuromodulation: From the Workbench to the Bedside by : Matteo Bologna
Download or read book Innovative Technologies and Clinical Applications for Invasive and Non-Invasive Neuromodulation: From the Workbench to the Bedside written by Matteo Bologna and published by Frontiers Media SA. This book was released on 2020-02-13 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The possibility of harvesting the power of electric and magnetic impulses in the human body, commonly referred to as “neuromodulation,” is one of the most recent and promising developments of the modern science. Since the late ´60s, multiple invasive and non-invasive technologies have been developed and tested in experimental and clinical settings with the final aim of modulating the function of the central and peripheral nervous system. Clinical applications include, but are not limited to, common neurological disorders such as Parkinson’s disease and other movement disorders. The bulk of evidence supporting the clinical efficacy of various invasive and non-invasive approaches for neuromodulation has progressively led scientific societies, patients’ associations, and regulatory entities to acknowledge the critical role played by neuromodulation in the therapeutic algorithms of a wide range of neurological disorders. As a result, new technologies have been recently introduced into the market or are currently under validation. Their potential implementation into innovative protocols for neuromodulation demands a critical revision of what are the unmet needs for neuromodulation in movement disorders.
Book Synopsis Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences by : Bernardo Dell'Osso
Download or read book Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences written by Bernardo Dell'Osso and published by Springer Nature. This book was released on 2020-07-31 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.
Book Synopsis The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders by : Lindsay M. Oberman
Download or read book The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders written by Lindsay M. Oberman and published by Frontiers Media SA. This book was released on 2015-12-03 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged.
Book Synopsis Emerging Horizons in Neuromodulation: New Frontiers in Brain and Spine Stimulation by :
Download or read book Emerging Horizons in Neuromodulation: New Frontiers in Brain and Spine Stimulation written by and published by Academic Press. This book was released on 2021-08-24 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Neurobiology series
Book Synopsis The Stimulated Brain by : Roi Cohen Kadosh
Download or read book The Stimulated Brain written by Roi Cohen Kadosh and published by Elsevier. This book was released on 2014-06-01 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available
Book Synopsis Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders by :
Download or read book Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders written by and published by Elsevier. This book was released on 2021-07-09 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders, Volume 264 presents the latest updates on recent techniques used to examine the potential treatment of psychiatric and neurological disorders in adults. In this special issue, the book's authors and contributors provide a unique focus on the potential effects of non-invasive brain stimulation. Topics cover a range of reviews, opinions, methodologies, original research articles, and suggestions on how to better translate scientific knowledge into practice. This new release will help guide basic research and the development of therapeutic interventions for children and adolescents who suffer from neurodevelopmental disorders. Covers the effects of brain stimulation on different neurodevelopmental disorders Includes experimental studies in humans, animals and associated theoretical reviews Provides the most accurate and up-to-date coverage from selected international experts
Book Synopsis Measuring and Modulating the Brain with Non-invasive Stimulation by :
Download or read book Measuring and Modulating the Brain with Non-invasive Stimulation written by and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Combining a non-invasive transcranial stimulation technique with another therapeutic approach: mechanisms of action, therapeutic interest and tolerance by : Jean Paul Buu Cuong Nguyen
Download or read book Combining a non-invasive transcranial stimulation technique with another therapeutic approach: mechanisms of action, therapeutic interest and tolerance written by Jean Paul Buu Cuong Nguyen and published by Frontiers Media SA. This book was released on 2024-07-23 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous publications have attested to the therapeutic efficacy of non-invasive brain stimulation (NIBS) techniques, such as repetitive transcranial magnetic stimulation (rTMS) and low-intensity transcranial electrical stimulation (tES). These methods have been used in the treatment of various neurological-related conditions, such as chronic pain, cognitive disorders, movement disorders, or stroke rehabilitation. Across these different fields, evidence suggests therapeutic efficacy could be improved when combining NIBS technique in combination with another type of more commonly utilized therapeutic approaches (e.g., motor and/or cognitive training, pharmacological, physical and neurorehabilitation).
Book Synopsis Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders by : Bahman Zohuri
Download or read book Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders written by Bahman Zohuri and published by Academic Press. This book was released on 2022-08-20 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders examines the non-invasive application of electrical stimulation of the brain to treat neurological disorders, and to enhance individual/group performance. This volume discusses emerging electro-technologies such as transcranial direct current/alternating current electric fields and pulsed magnetic fields to treat many of these common medical problems. Chapters begin by examining foundations of electromagnetic theory and wave equations that underly these technologies before discussing methods to treat disorders, the impact of technology and mental health and artificial intelligence. Discussing over 40 neurological diseases, this book presents coverage of techniques to treat stroke, epilepsy, Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, depression, schizophrenia, and many other diseases of the nervous system. Compares techniques so users can select ideal methods for their experiment Provides a focused tutorial introduction to core diseases of the nervous system, including stroke, epilepsy, Alzheimer’s, Parkinson’s, head and spinal cord trauma, schizophrenia, and more Covers more than 40 diseases, from foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics and neuroscience Provides walk-through boxes that guide students step-by-step through the experiment
Book Synopsis Non-invasive Brain Stimulation in Neurology and Psychiatry by :
Download or read book Non-invasive Brain Stimulation in Neurology and Psychiatry written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (TDCS), modify brain function through interaction with multiple neurotransmitters and networks. The implementation of these non-invasive stimulation techniques in physiology, behavioral studies, with modelling or functional imaging has provided an outstanding causal link between brain structure and function and helped identify neural networks mediating cognitive or motor function. The potential efficacy of non-invasive brain stimulation procedures for the management of specific symptoms in diverse neurological and psychiatric conditions has been tested in the past decade or so. For example, repetitive TMS over prefrontal areas has been extensively investigated as a treatment for patients with medication-resistant depression and has been shown to be associated with improvement of mood. Similarly, non-invasive stimulation techniques have been applied to various symptoms of Parkinson's disease such as bradykinesia and dyskinesias, with variables degrees of success reported. However, attempts to expand previously observed clinical improvements to other neurological disorders (e.g. Tourette's syndrome, autism, epilepsy) has been controversial. In trying to bypass potential confounding elements, researchers aim to target neural populations altered in disease to either increase or decrease their corrupted baseline activity. In addition, a complementary approach is to extend stimulation protocols that results enhanced behavior in healthy participants. One of the potential limitation of this latter strategy has been that most of the protocols evaluated in healthy participants have been tested in populations that are not comparable to the patient populations. This Frontiers Research Topic on non-invasive brain stimulation and enhancement of function seeks to combine contributions from researchers who found non-invasive brain stimulation induced improvement of either a motoric, cognitive or behavioral nature investigated behaviorally, physiologically or using brain imaging techniques in clinical populations. Investigation of the relation between enhancement of function in healthy populations and improvement of symptoms in patients with neurological or psychiatric disorders needs further consideration. Critically, the topic will be centered on the following topics to expand current knowledge: • selection of adequate stimulation protocols, including simple questions such as whether TMS or TDCS is more efficacious for inducing enhancement of function in brain disease; • methodological issues such as optimizing cortical targets and the use of good control groups; • which symptoms to tackle in different brain disorders. For example, is it possible to de-activate hyperactive cortical regions present in Parkinson disease to induce clinical amelioration? Do protocols used in healthy populations produce similar predictable effects in parkinsonian persons?; • potential of using stimulation protocols in combination with pharmacological or cognitive therapy; • the use of appropriate clinical, behavioral, physiological and imaging tools to measure brain plastic changes. Consideration about possible multi-centre clinical trials: feasibility, problems and authorization pathways. Studies or reviews on cost-effectiveness. The aim of this topic is to determine which disease signs are treatable with non-invasive brain stimulation and available protocols to interfere with altered brain systems and produce enhanced motor and behavior outcomes. This Frontiers Research Topic will be important in identifying new avenues of clinical research for rapid advances in the field.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309376211 Total Pages :103 pages Book Rating :4.3/5 (93 download)
Book Synopsis Non-Invasive Neuromodulation of the Central Nervous System by : National Academies of Sciences, Engineering, and Medicine
Download or read book Non-Invasive Neuromodulation of the Central Nervous System written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-11-02 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and non-therapeutic applications of non-invasive neuromodulation will continue to expand in coming years, particularly for indications where treatments are currently insufficient, such as drug-resistant depression. Given the growing interest in non-invasive neuromodulation technologies, the Institute of Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop, inviting a range of stakeholders - including developers of devices and new technologies, researchers, clinicians, ethicists, regulators, and payers - to explore the opportunities, challenges, and ethical questions surrounding the development, regulation, and reimbursement of these devices for the treatment of nervous system disorders as well as for non-therapeutic uses, including cognitive and functional enhancement. This report highlights the presentation and discussion of the workshop.
Book Synopsis Motor Cortex Inhibition with Somatosensory and Transcranial Direct Current Stimulation by : Anita Mary Trudgen
Download or read book Motor Cortex Inhibition with Somatosensory and Transcranial Direct Current Stimulation written by Anita Mary Trudgen and published by . This book was released on 2018 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Priming the brain may provide potential treatment strategies for neurological disorders and stroke. Mesh glove stimulation (MGS) provides a non-motor target for rehabilitation. Following 30 minutes of suprasensory threshold MGS there is an increase in corticomotor excitability that is likely mediated by long-term potentiation. Transcranial direct current stimulation (tDCS) of the primary motor cortex can induce global changes in corticomotor excitability. Nine minutes of cathodal tDCS (c-tDCS) produces a lasting decrease in corticomotor excitability mediated by long-term depression. Whether priming MGS with c-tDCS further enhances corticomotor excitability through homeostatic metaplasticity mechanisms is unknown. Sixteen right-handed neurologically healthy individuals (9 female, 19-36 years) participated in a repeated measures cross-over study, nine minutes of sham- or c-tDCS followed by 30 minutes of suprasensory threshold MGS. Single-pulse transcranial magnetic stimulation (rest motor threshold and motor evoked potential amplitude), paired-pulse transcranial magnetic stimulation (intracortical facilitation, short afferent inhibition (SAI), short interval intracortical inhibition (SICI), and SAI with SICI (SAIxSICI)), and motor performance (grooved pegboard test) of the left hand were obtained at baseline, post-tDCS, and immediately, 30 and 60 minutes post-MGS. There was more disinhibition of SAI, and an increase in rest motor threshold and SAIxSICI after MGS was primed with c-tDCS compared with sham-tDCS. There was also a greater improvement in the grooved pegboard task after c-tDCS primed MGS than sham. Our results indicate a non-homeostatic metaplastic modulation of corticomotor excitability with c-tDCS primed MGS. Consequently, c-tDCS did not modulate corticomotor excitability after MGS, but did improve motor performance. Therefore, c-tDCS may be an effective priming modality to induce non-homeostatic metaplasticity.
Book Synopsis Transcranial Brain Stimulation by : Carlo Miniussi
Download or read book Transcranial Brain Stimulation written by Carlo Miniussi and published by CRC Press. This book was released on 2012-12-03 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal pathways. In addition, these techniques have been found
Book Synopsis Human Machine Interface-based Neuromodulation Solutions for Neurorehabilitation by : Jing Wang
Download or read book Human Machine Interface-based Neuromodulation Solutions for Neurorehabilitation written by Jing Wang and published by Frontiers Media SA. This book was released on 2022-10-06 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy
Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Book Synopsis Synaptic Plasticity by : Michael R. Kreutz
Download or read book Synaptic Plasticity written by Michael R. Kreutz and published by Springer Science & Business Media. This book was released on 2012-02-18 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
