Non-Canonical Autophagy

Download Non-Canonical Autophagy PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128209119
Total Pages : 184 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!


Book Synopsis Non-Canonical Autophagy by : Giulia Petroni

Download or read book Non-Canonical Autophagy written by Giulia Petroni and published by Academic Press. This book was released on 2021-04-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non-canonical' autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. - Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy - Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes - Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

Regulation of B Cell Responses by Non-canonical Autophagy

Download Regulation of B Cell Responses by Non-canonical Autophagy PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (119 download)

DOWNLOAD NOW!


Book Synopsis Regulation of B Cell Responses by Non-canonical Autophagy by : Paula Maldonado Villavicencio

Download or read book Regulation of B Cell Responses by Non-canonical Autophagy written by Paula Maldonado Villavicencio and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Study on Non-canonical Autophagy Signalling

Download A Study on Non-canonical Autophagy Signalling PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

DOWNLOAD NOW!


Book Synopsis A Study on Non-canonical Autophagy Signalling by : Cansu Karabiyik

Download or read book A Study on Non-canonical Autophagy Signalling written by Cansu Karabiyik and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

ATG8 Regulation and Function in Non-canonical Autophagy

Download ATG8 Regulation and Function in Non-canonical Autophagy PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

DOWNLOAD NOW!


Book Synopsis ATG8 Regulation and Function in Non-canonical Autophagy by : Katherine Sloan

Download or read book ATG8 Regulation and Function in Non-canonical Autophagy written by Katherine Sloan and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Canonical and Non-canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System

Download Canonical and Non-canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (987 download)

DOWNLOAD NOW!


Book Synopsis Canonical and Non-canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System by : Rebecca Bohn

Download or read book Canonical and Non-canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System written by Rebecca Bohn and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Mechanisms of Atg16L1 Recruitment in Non-canonical Autophagy

Download Novel Mechanisms of Atg16L1 Recruitment in Non-canonical Autophagy PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (11 download)

DOWNLOAD NOW!


Book Synopsis Novel Mechanisms of Atg16L1 Recruitment in Non-canonical Autophagy by : Katherine Anne Fletcher

Download or read book Novel Mechanisms of Atg16L1 Recruitment in Non-canonical Autophagy written by Katherine Anne Fletcher and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Membrane Biogenesis

Download Membrane Biogenesis PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642731848
Total Pages : 474 pages
Book Rating : 4.6/5 (427 download)

DOWNLOAD NOW!


Book Synopsis Membrane Biogenesis by : Jos A.F. Op den Kamp

Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Non-canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation

Download Non-canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (1 download)

DOWNLOAD NOW!


Book Synopsis Non-canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation by : Christian Wolfgang Keller

Download or read book Non-canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation written by Christian Wolfgang Keller and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Non-canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones

Download The Non-canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 47 pages
Book Rating : 4.:/5 (976 download)

DOWNLOAD NOW!


Book Synopsis The Non-canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones by :

Download or read book The Non-canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones written by and published by . This book was released on 2016 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: The canonical autophagy pathway has primarily been described as a degradative mechanism, which clears the cell of old damaged organelles, protein aggregates and pathogens. Central to the pathway is the de novo formation of a vesicle structure called the autophagosome, which fuses with lysosomes to degrade its content. The Atg8a/MAP1-LC3 protein family is essential for the formation of the autophagosome, and Atg8a mutations result in a variety of defects related to decreased autophagic function. Recently, we have observed a phenotype in Atg8a mutant Drosophila that is consistent with secretory defects of the peptide hormone Bursicon, which is responsible for wing expansion and cuticle hardening upon eclosion. This observation is in accordance with other recent findings which show that components of the autophagy pathway are also involved in the secretion of bioactive molecules. However, the intersection of autophagy and secretory pathways is not yet fully understood. Here, we show that along with Bursicon two additional peptide hormones are differentially secreted and show impaired hemolymph profiles when autophagic function is lowered in the fly nervous system. This includes the release of the pigment dispersing factor (PDF, circadian cycle) and the mesencephalic astrocyte-derived neurotrophic factor (dMANF, stress response), which is highlighted by the aberrant sleep-circadian behaviors (PDF) and trauma-mediated sensitivity (MANF) associated with Atg8a1 mutant flies. Based on the Bursicon wing phenotype, we conducted a secretion-based screen using the GAL4/UAS-dsRNAi knockdown system and identified Atg8a and other autophagy components involved with organelle initiation and membrane expansion that show impaired Bursicon release upon knockdown. Furthermore, this did not include genes involved with selective autophagy (aggrephagy) or endosomal-lysosomal trafficking. Findings from this research will have broad implications toward understanding complex secretory defects and the intersection of autophagy with other vesicle trafficking pathways.

Canonical and Non-canonical Roles of Macroautophagy Proteins in Synaptic Plasticity and Neuronal Physiology

Download Canonical and Non-canonical Roles of Macroautophagy Proteins in Synaptic Plasticity and Neuronal Physiology PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

DOWNLOAD NOW!


Book Synopsis Canonical and Non-canonical Roles of Macroautophagy Proteins in Synaptic Plasticity and Neuronal Physiology by : Akrivi Dimitra Daskalaki

Download or read book Canonical and Non-canonical Roles of Macroautophagy Proteins in Synaptic Plasticity and Neuronal Physiology written by Akrivi Dimitra Daskalaki and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thèse. Biologie. Médecine. 2023

Examining the Role of Autophagy in Osteoclast Function

Download Examining the Role of Autophagy in Osteoclast Function PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)

DOWNLOAD NOW!


Book Synopsis Examining the Role of Autophagy in Osteoclast Function by : Anh Nhi Tran

Download or read book Examining the Role of Autophagy in Osteoclast Function written by Anh Nhi Tran and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Autophagy and Cancer

Download Autophagy and Cancer PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461465613
Total Pages : 267 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!


Book Synopsis Autophagy and Cancer by : Hong-Gang Wang

Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

Plant Cell Membranes

Download Plant Cell Membranes PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 :
Total Pages : 806 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!


Book Synopsis Plant Cell Membranes by : Lester Packer

Download or read book Plant Cell Membranes written by Lester Packer and published by Academic Press. This book was released on 1987-11-28 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

Cell Death

Download Cell Death PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535122363
Total Pages : 448 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!


Book Synopsis Cell Death by : Tobias Ntuli

Download or read book Cell Death written by Tobias Ntuli and published by BoD – Books on Demand. This book was released on 2015-12-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Protein Phosphorylation in Human Health

Download Protein Phosphorylation in Human Health PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535107372
Total Pages : 482 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!


Book Synopsis Protein Phosphorylation in Human Health by : Cai Huang

Download or read book Protein Phosphorylation in Human Health written by Cai Huang and published by BoD – Books on Demand. This book was released on 2012-09-06 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: 15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.

Autophagy of the Nervous System

Download Autophagy of the Nervous System PDF Online Free

Author :
Publisher : World Scientific
ISBN 13 : 9814350443
Total Pages : 441 pages
Book Rating : 4.8/5 (143 download)

DOWNLOAD NOW!


Book Synopsis Autophagy of the Nervous System by : Zhenyu Yue

Download or read book Autophagy of the Nervous System written by Zhenyu Yue and published by World Scientific. This book was released on 2012 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy.

Autophagy: Biology and Diseases

Download Autophagy: Biology and Diseases PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 9811506027
Total Pages : 727 pages
Book Rating : 4.8/5 (115 download)

DOWNLOAD NOW!


Book Synopsis Autophagy: Biology and Diseases by : Zheng-Hong Qin

Download or read book Autophagy: Biology and Diseases written by Zheng-Hong Qin and published by Springer Nature. This book was released on 2019-11-27 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.