Nitric Oxide Dependence Calculations

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Nitric Oxide Dependence Calculations

Author : Melisa Erdal
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis Nitric Oxide Dependence Calculations by : Melisa Erdal

Download or read book Nitric Oxide Dependence Calculations written by Melisa Erdal and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial microvascular function of skin blood vessels is predictive of the cardiovascular disease risk (Holowatz et al., 2008). This study aims to examine differences in nitric oxide- (NO) dependent vasodilation during 39°C and 42°C local heating protocols and determine if the method of calculating NO contribution influences findings. We hypothesized that NO would contribute more to vasodilation when the skin blood flow (SkBF) values are subtracted (traditional) rather than the contribution value calculated from the percent change (relative). In addition, we hypothesized that older subjects would have reduced NO-dependent vasodilation in both protocols and with both methods of analysis. We conducted a cross-sectional study of 31 young (12 male/19 female, 24 (4) years) and 18 older (5 male/13 female, 68 (7.517)) participants. NO-dependent vasodilation was determined by perfusing (intradermal microdialysis) 15 nM N-nitro-l-arginine methyl ester during the heating plateau of the 39°C and 42°C protocols. Red blood cell flux (laser-Doppler flowmetry) was used to calculate cutaneous vascular conductance (CVC; red blood cell flux/mean arterial pressure), and values were represented as a percentage of maximum (%CVCmax) (28 nM sodium nitroprusside + 43°C). We found that when NO contribution is analyzed with the traditional method, NO contribution was lower in the older group than the young group in the 39°C heating protocol (p=0.030) but not in the 42°C protocol (p=0.262). We also found that NO contribution was lower in the 39°C protocol in the older group (p

Methods in Nitric Oxide Research

Author : Martin Feelisch
Publisher :
ISBN 13 :
Total Pages : 746 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Methods in Nitric Oxide Research by : Martin Feelisch

Download or read book Methods in Nitric Oxide Research written by Martin Feelisch and published by . This book was released on 1996-06-04 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes methods for the measurement and investigation of nitric oxide. The topics discussed include the metabolism of substrates and cofactors, the detection of nitrogen oxides, the detection of nitrogen oxide synthase activity, and the detection of adducts and reaction products.

Emergent neural computation from the interaction of different forms of plasticity

Author : Cristina Savin
Publisher : Frontiers Media SA
ISBN 13 : 2889197883
Total Pages : 195 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Emergent neural computation from the interaction of different forms of plasticity by : Cristina Savin

Download or read book Emergent neural computation from the interaction of different forms of plasticity written by Cristina Savin and published by Frontiers Media SA. This book was released on 2016-03-22 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the propagation of neural activity through synapses, to the integration of signals in the dendritic arbor, and the processes determining action potential generation, virtually all aspects of neural processing are plastic. This plasticity underlies the remarkable versatility and robustness of cortical circuits: it enables the brain to learn regularities in its sensory inputs, to remember the past, and to recover function after injury. While much of the research into learning and memory has focused on forms of Hebbian plasticity at excitatory synapses (LTD/LTP, STDP), several other plasticity mechanisms have been characterized experimentally, including the plasticity of inhibitory circuits (Kullmann, 2012), synaptic scaling (Turrigiano, 2011) and intrinsic plasticity (Zhang and Linden, 2003). However, our current understanding of the computational roles of these plasticity mechanisms remains rudimentary at best. While traditionally they are assumed to serve a homeostatic purpose, counterbalancing the destabilizing effects of Hebbian learning, recent work suggests that they can have a profound impact on circuit function (Savin 2010, Vogels 2011, Keck 2012). Hence, theoretical investigation into the functional implications of these mechanisms may shed new light on the computational principles at work in neural circuits. This Research Topic of Frontiers in Computational Neuroscience aims to bring together recent advances in theoretical modeling of different plasticity mechanisms and of their contributions to circuit function. Topics of interest include the computational roles of plasticity of inhibitory circuitry, metaplasticity, synaptic scaling, intrinsic plasticity, plasticity within the dendritic arbor and in particular studies on the interplay between homeostatic and Hebbian plasticity, and their joint contribution to network function.

Biophysics of Computation

Author : Christof Koch
Publisher : Oxford University Press
ISBN 13 : 0190292857
Total Pages : 588 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Biophysics of Computation by : Christof Koch

Download or read book Biophysics of Computation written by Christof Koch and published by Oxford University Press. This book was released on 2004-10-28 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes. Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation. Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.

The Kinetics of the Reduction of Nitric Oxide by Tin(II).

Author : Dan Eldon Hendriksen
Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.:/5 (35 download)

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Book Synopsis The Kinetics of the Reduction of Nitric Oxide by Tin(II). by : Dan Eldon Hendriksen

Download or read book The Kinetics of the Reduction of Nitric Oxide by Tin(II). written by Dan Eldon Hendriksen and published by . This book was released on 1975 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Haemodynamic Effects Of Nitric Oxide

Author : Tudor M Griffith
Publisher : World Scientific
ISBN 13 : 1783262478
Total Pages : 541 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis The Haemodynamic Effects Of Nitric Oxide by : Tudor M Griffith

Download or read book The Haemodynamic Effects Of Nitric Oxide written by Tudor M Griffith and published by World Scientific. This book was released on 1999-08-30 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of nitric oxide as an endothelium-derived relaxing factor in 1987, investigations on its precise modes of action have been carried out at an extraordinary rate. Nitric oxide is now implicated in many physiological and pathological processes — not just in the control of vascular resistance, but in nerve transmission, cell proliferation, inflammatory responses and so on.Despite such rapid progress, no attempt has been made to combine the current knowledge of this subject matter in a single textbook. This volume has been written with the above in mind and presents a topical, comprehensive overview of the biochemistry and the physiological and pathophysiological effects of nitric oxide as they relate to the cardiovascular system. The therapeutic implications of nitric oxide are also considered. The text comprises contributions from many of the leading international authorities on the topic including Professor L J Ignarro, winner of the 1998 Nobel Prize in Physiology or Medicine.

Nitric Oxide and the Cardiovascular System

Author : Joseph Loscalzo
Publisher : Springer Science & Business Media
ISBN 13 : 1592590020
Total Pages : 589 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Nitric Oxide and the Cardiovascular System by : Joseph Loscalzo

Download or read book Nitric Oxide and the Cardiovascular System written by Joseph Loscalzo and published by Springer Science & Business Media. This book was released on 2000-03-29 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinical and experimental investigators comprehensively review the chemistry, biochemistry, molecular biology, physiology, and pathophysiology of nitric oxide in the cardiovascular systems. These experts particularly illuminate nitric oxide biology, its cardiovascular pathophysiology, and its role in cardiovascular therapeutics. Topics also included are the development of nitric oxide donors for the treatment of myocardial ischemia and thrombosis, the development of gene therapeutic restoration of endothelial function in atherosclerosis, and the application of nitric oxide biology to investigative arenas in cardiovascular medicine. With its balanced presentation of basic and clinically relevant information, Nitric Oxide and the Cardiovascular System provides a comprehensive, authoritative guide for all those cardiovascular biologists, cardiologists, physiologists, and cardiovascular surgeons engaged in today's clinical or experimental research.

WHO Guidelines for Indoor Air Quality

Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis WHO Guidelines for Indoor Air Quality by :

Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Cell Type Dependent Release of Nitric Oxide And, Or Reactive Nitrogen Oxide Species from Intracellular SIN-1

Author : Andrea Ulrike Swintek
Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.:/5 (181 download)

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Book Synopsis Cell Type Dependent Release of Nitric Oxide And, Or Reactive Nitrogen Oxide Species from Intracellular SIN-1 by : Andrea Ulrike Swintek

Download or read book Cell Type Dependent Release of Nitric Oxide And, Or Reactive Nitrogen Oxide Species from Intracellular SIN-1 written by Andrea Ulrike Swintek and published by . This book was released on 2005 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nitric Oxide Protocols

Author : Aviv Hassid
Publisher : Springer Science & Business Media
ISBN 13 : 1592598072
Total Pages : 251 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Nitric Oxide Protocols by : Aviv Hassid

Download or read book Nitric Oxide Protocols written by Aviv Hassid and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carrying on the high standards of the much-praised first edition of Nitric Oxide Protocols, Aviv Hassid has brought together a panel of expert researchers and clinician scientists to describe in step-by-step detail the latest methodologies for the measurement of nitric oxide--and the enzyme that produces it-in biological tissues and fluids. The authors take advantage of the latest methodologies for the quantitation of biological fluids and tissues, including capillary electrophoresis, microcoaxial electrodes, in vivo measurement of nitric oxide in exhaled air, confocal microscopy, gas chromatography, in situ hybridization, and real-time polymerase chain reaction. Chapters on the measurement of the novel products of nitric oxide, such as nitrated proteins, S-nitrosylated proteins, and dioxygen-dependent NO metabolism, are also included. Additional chapters address the expression of nitric oxide synthase via the use of viral vectors in gene therapy for erectile dysfunction and cancer, as well as in retrovirus, adenovirus, or adenoassociated virus-mediated expression of nitric oxide synthase in vivo. The protocols follow the successful Methods in Molecular BiologyTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Nitric Oxide Protocols, 2nd ed., offers investigators and clinican/scientists a gold-standard collection of readily reproducible analytical techniques for measuring levels of nitric oxide and determining its manifold functions and effects.

Nitrogen oxides (NOx) why and how they are controlled

Author :
Publisher : DIANE Publishing
ISBN 13 : 1428902805
Total Pages : 57 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Nitrogen oxides (NOx) why and how they are controlled by :

Download or read book Nitrogen oxides (NOx) why and how they are controlled written by and published by DIANE Publishing. This book was released on 1999 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Geophysics and Space Environments

Author : U.S. Air Force Geophysics Laboratory
Publisher :
ISBN 13 :
Total Pages : 1066 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Handbook of Geophysics and Space Environments by : U.S. Air Force Geophysics Laboratory

Download or read book Handbook of Geophysics and Space Environments written by U.S. Air Force Geophysics Laboratory and published by . This book was released on 1985 with total page 1066 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Inorganic Chemistry, Volume 50

Author : Kenneth D. Karlin
Publisher : John Wiley & Sons
ISBN 13 : 047146077X
Total Pages : 641 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Progress in Inorganic Chemistry, Volume 50 by : Kenneth D. Karlin

Download or read book Progress in Inorganic Chemistry, Volume 50 written by Kenneth D. Karlin and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 50 continues to report recent advances with a significant, up-to-date selection of contributions on topics such as the following: Structural and mechanistic investigations in asymmetric copper; Catalyzed reactions; Phenoxyl radical complexes; Synthesis of large pore zeolites and molecular sieves; Inorganic nanoclusters with fullerene-like structure and nanotubes

Glycerol and the Glycols

Author : James Wright Lawrie
Publisher :
ISBN 13 :
Total Pages : 460 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Glycerol and the Glycols by : James Wright Lawrie

Download or read book Glycerol and the Glycols written by James Wright Lawrie and published by . This book was released on 1928 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Calculations - E-Book

Author : Joyce LeFever Kee
Publisher : Elsevier Health Sciences
ISBN 13 : 0323674224
Total Pages : 4094 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Clinical Calculations - E-Book by : Joyce LeFever Kee

Download or read book Clinical Calculations - E-Book written by Joyce LeFever Kee and published by Elsevier Health Sciences. This book was released on 2020-06-12 with total page 4094 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. NEW! Updated practice problems across the text incorporate the latest drugs and dosages.

Physics Briefs

Author :
Publisher :
ISBN 13 :
Total Pages : 1420 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Physics Briefs by :

Download or read book Physics Briefs written by and published by . This book was released on 1993 with total page 1420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Upper Mesosphere and Lower Thermosphere

Author : R. M. Johnson
Publisher : American Geophysical Union
ISBN 13 : 0875900445
Total Pages : 354 pages
Book Rating : 4.8/5 (759 download)

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Book Synopsis The Upper Mesosphere and Lower Thermosphere by : R. M. Johnson

Download or read book The Upper Mesosphere and Lower Thermosphere written by R. M. Johnson and published by American Geophysical Union. This book was released on 1995-01-09 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published by the American Geophysical Union as part of the Geophysical Monograph Series, Volume 87. This volume provides a review of progress made in recent years in experimental and theoretical investigation of the upper mesosphere and lower thermosphere and coupling between these regions and the ionosphere. Detailed study of the mesosphere/lower thermosphere/ionosphere (MLTI) region has historically been difficult because of its relative inaccessibility to direct measurement techniques and the complex and highly coupled processes which occur there. Although we have still not successfully unraveled all these complex interactions, we have made significant recent progress toward a fuller understanding of the basic state of the MLTI and of the dominant wave and coupling processes. This monograph includes a set of tutorial papers, which review our current understanding of aspects of the MLTI. These tutorials are interspersed with a selection of papers describing research progress on various topics of current interest in this region. The book should therefore be useful both to the newcomer, as an introduction to this field of research, and to the more experienced researcher, providing an overview of research in progress as well as a convenient reference collection of papers describing our current understanding.