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New Insights On Renin Angiotensin System In The Kidney
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Book Synopsis New Insights on Renin-Angiotensin System in the Kidney by : Norimoto Yanagawa
Download or read book New Insights on Renin-Angiotensin System in the Kidney written by Norimoto Yanagawa and published by S. Karger AG (Switzerland). This book was released on 1991-01-01 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Renin-Angiotensin System and the Kidney by : Xiao C. Li
Download or read book The Renin-Angiotensin System and the Kidney written by Xiao C. Li and published by Biota Publishing. This book was released on 2015-03-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renin-angiotensin system (RAS) is one of the most important endocrine (tissue-to-tissue), paracrine (cell-to-cell) and intracrine (intracellular/nuclear) humoral systems in the regulation of blood pressure, cardiovascular, and kidney function in health and disease. The RAS has remarkably evolved from the initial discovery of the rate-limiting enzyme renin to a complex biochemical and physiological cascade involving more than a dozen members. Currently, there are up to five axes or pathways identified in the RAS; each has its substrate, enzyme, effector peptide, receptor, and downstream signaling pathways. These include the renin/ACE/ANG II/AT1 receptor, the APA/ANG III/AT2 receptor, the ACE2/ANG (1-7)/Mas receptor, the prorenin/prorenin receptor (PRR), and the ANG IV/AT4 receptor (IRAP) pathways. Accordingly, the roles of the RAS have expanded well beyond the classic endocrine paradigm as a powerful vasoconstrictor, a potent aldosterone stimulator, or a sodium-retaining hormonal system. The goals of this article are to review and discuss the current insights into and new perspectives on the expression, localization, and novel actions of the RAS with a focus in the kidney. Special emphasis will be placed on recently discovered new members of the RAS derived from studies using innovative mutant rats or mice that either overexpress (knockin) or are deficient (knockout) of a particular substrate, enzyme, ANG peptide, or receptor. This new knowledge will help improve our understanding how each of these pathways act directly or indirectly to regulate blood pressure, cardiovascular and kidney function in physiology, and can be targeted to treat hypertension, cardiovascular and renal diseases.
Book Synopsis New Insights on the Renin-angiotensin System in the Kidney by :
Download or read book New Insights on the Renin-angiotensin System in the Kidney written by and published by . This book was released on 1991 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Renin-Angiotensin Aldosterone System by : Samy I. McFarlane
Download or read book Renin-Angiotensin Aldosterone System written by Samy I. McFarlane and published by BoD – Books on Demand. This book was released on 2021-11-24 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Renin-Angiotensin Aldosterone System (RAAS) plays an important role not only in salt and water homeostasis but also in the cardiovascular system, the kidney, and the brain. While several volumes address different aspects of the RAAS function, this book provides cutting-edge information on the pathogenesis of various disorders related to RAAS overactivation. It also presents unique aspects of RAAS functioning that have not been sufficiently described in the literature. Topics covered include assessment of hypoaldosteronism in infancy, RASS and cognitive decline, and the role of RAAS in the pathogenesis of COVID-19. Written by experts in the field in an easy-to-follow and illustrated format, this volume will benefit students and practitioners, as well as clinical and basic science investigators alike.
Book Synopsis Textbook of Nephro-Endocrinology by : Ajay K. Singh
Download or read book Textbook of Nephro-Endocrinology written by Ajay K. Singh and published by Academic Press. This book was released on 2009-01-12 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field
Book Synopsis The Cancer Stem Cell Niche by : Susie Nilsson
Download or read book The Cancer Stem Cell Niche written by Susie Nilsson and published by Academic Press. This book was released on 2021-02-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on the Cancer Stem Cell Niche
Book Synopsis Experimental Hypertension by : William Goldring
Download or read book Experimental Hypertension written by William Goldring and published by . This book was released on 2012-06-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited By Roy Waldo Miner, W. W. Swingle, And Michael Demarest. Preface By Irvine H. Page. Additional Authors Include L. F. Leloir, Arthur Grollman, G. E. Wakerlin, And Many Others.
Book Synopsis Aldosterone-Mineralocorticoid Receptor by : Brian Harvey
Download or read book Aldosterone-Mineralocorticoid Receptor written by Brian Harvey and published by BoD – Books on Demand. This book was released on 2019-09-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
Book Synopsis Renin Angiotensin System and the Heart by : Walmor C. De Mello
Download or read book Renin Angiotensin System and the Heart written by Walmor C. De Mello and published by John Wiley & Sons. This book was released on 2005-10-31 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research
Book Synopsis New Insights in Vertebrate Kidney Function by : Judith Anne Brown
Download or read book New Insights in Vertebrate Kidney Function written by Judith Anne Brown and published by Cambridge University Press. This book was released on 1993-04-22 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important collection of reviews summarising our current understanding of the working of the vertebrate kidney.
Author :A. Treviño-Becerra Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318062510 Total Pages :150 pages Book Rating :4.3/5 (18 download)
Book Synopsis Uric Acid in Chronic Kidney Disease by : A. Treviño-Becerra
Download or read book Uric Acid in Chronic Kidney Disease written by A. Treviño-Becerra and published by Karger Medical and Scientific Publishers. This book was released on 2018-01-23 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuricemia is thus expected to be beneficial for both the general population and CKD patients. This book presents new information on uric acid in tubular transport, early recognition of renal lesions, genetic predisposition, preeclampsia, metabolic syndrome, diabetes, high blood pressure in the young, and the relationship with vitamin D. Moreover, the relationship between AKI and uric acid, as well as the rejection of renal transplants due to hyperuricemia, are discussed. This publication will be of interest to both general practitioners and researchers working in the field of CKD. It provides new insights into renal damage caused by hyperuricemia and into prevention and treatment possibilities.
Book Synopsis The Protective Arm of the Renin Angiotensin System (RAS) by : Thomas Unger
Download or read book The Protective Arm of the Renin Angiotensin System (RAS) written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.
Book Synopsis Drugs, Enzymes and Receptors of the Renin-Angiotensin System by : Ahsan Husain
Download or read book Drugs, Enzymes and Receptors of the Renin-Angiotensin System written by Ahsan Husain and published by CRC Press. This book was released on 2000-02-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and unique feature of this book is that a commentary on each chapter, written by an independent peer or peers, is included to present alternative views, greater depth and a different perspective. Clinicians and researchers alike will find this volume a stimulating, and perhaps even entertaining, addition to their libraries. .
Book Synopsis New Insights Into Renal Fibrosis and Therapeutic Effects of Natural Products by : Dan-Qian Chen
Download or read book New Insights Into Renal Fibrosis and Therapeutic Effects of Natural Products written by Dan-Qian Chen and published by Frontiers Media SA. This book was released on 2022-05-30 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New insights into renal fibrosis and therapeutic effects of natural products, volume II by : Dan-Qian Chen
Download or read book New insights into renal fibrosis and therapeutic effects of natural products, volume II written by Dan-Qian Chen and published by Frontiers Media SA. This book was released on 2023-04-19 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hypertension: New Insights for the Healthcare Professional: 2012 Edition by :
Download or read book Hypertension: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hypertension. The editors have built Hypertension: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hypertension in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hypertension: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Chronic Kidney Disease: New Insights for the Healthcare Professional: 2013 Edition by :
Download or read book Chronic Kidney Disease: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Kidney Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Chronic Kidney Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Chronic Kidney Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
