New Frontiers Extracellular Vesicles

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New Frontiers: Extracellular Vesicles

Author : Suresh Mathivanan
Publisher : Springer Nature
ISBN 13 : 3030671712
Total Pages : 539 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis New Frontiers: Extracellular Vesicles by : Suresh Mathivanan

Download or read book New Frontiers: Extracellular Vesicles written by Suresh Mathivanan and published by Springer Nature. This book was released on 2021-03-29 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs. The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implications of EVs in intercellular communication and the significance of biologically active cargo carried within these EVs are further examined. Moreover, the numerous applications of EVs in diagnostics and treatment of diseases are reviewed in detail, particularly their potential as biomarkers and drug delivery vehicles. Taken together, this book is a compilation of the key implications of EVs that are secreted by virtually all cell types. Readers will gain a perspective into the biology, functions and applications of EVs and their constantly evolving knowledge base.

New Frontiers

Author :
Publisher :
ISBN 13 : 9783030671723
Total Pages : 539 pages
Book Rating : 4.6/5 (717 download)

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Book Synopsis New Frontiers by :

Download or read book New Frontiers written by and published by . This book was released on 2021 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs. The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implications of EVs in intercellular communication and the significance of biologically active cargo carried within these EVs are further examined. Moreover, the numerous applications of EVs in diagnostics and treatment of diseases are reviewed in detail, particularly their potential as biomarkers and drug delivery vehicles. Taken together, this book is a compilation of the key implications of EVs that are secreted by virtually all cell types. Readers will gain a perspective into the biology, functions and applications of EVs and their constantly evolving knowledge base.

New Frontiers in Extracellular Vesicles

Author : Erina Jimenez
Publisher : Foster Academics
ISBN 13 : 9781646465620
Total Pages : 0 pages
Book Rating : 4.4/5 (656 download)

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Book Synopsis New Frontiers in Extracellular Vesicles by : Erina Jimenez

Download or read book New Frontiers in Extracellular Vesicles written by Erina Jimenez and published by Foster Academics. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular vesicles (EVs) are lipid bilayer-delimited particles which are released naturally from nearly all types of cells but cannot replicate like cells. There are three types of EVs that are categorized on the basis of their size and synthesis route. These include apoptotic bodies, exosomes, and microvesicles. They transport a cargo of lipids, proteins, metabolites, nucleic acids and even parent cell organelles. The communication mechanism among cells relies heavily on EVs. They are also capable of carrying disease biomarkers, including CD24, glypican-1, CD63, and colon cancer-associated transcript 2 (CCAT2). Current research around EVs focuses on their role in various diseases and conditions such as cancer, neurodegeneration, metabolic disorders, and intercellular communication. Owing to their cargo delivery potential, EVs may be used as drug delivery platforms for cancer therapy. Furthermore, engineered EVs may find application in cancer combination therapy. This book explores the new frontiers in the study of extracellular vesicles. It is appropriate for students seeking detailed information on extracellular vesicles, as well as for experts.

Extracellular Vesicles

Author :
Publisher : Academic Press
ISBN 13 : 0128206632
Total Pages : 316 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Extracellular Vesicles by :

Download or read book Extracellular Vesicles written by and published by Academic Press. This book was released on 2020-10-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Novel Clinical Applications of Extracellular Vesicles

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Novel Clinical Applications of Extracellular Vesicles by :

Download or read book Novel Clinical Applications of Extracellular Vesicles written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particular, increasing concentrations of EVs have been found in many diseases such as cancer, autoimmune and cardiovascular diseases, among others. Most of the studies in EVs are focused on the characterization of EVs compounds, identifying mechanism of action, their potential use as biomarkers, and few of them investigate a therapeutic usage. However, there are some issues to be achieved on the path to their clinical application. This research topic offers a common place to discuss current and novel clinical applications of EVs pointing on future directions. We encouraged the submission of original articles, reviews, hypothesis, controversies, future perspectives and personal viewpoints on the following topics of interest, but not limited to: • Contribution of EVs to better understand the pathology of immunological diseases. • Standardization of isolation and quantification protocols in the daily clinical practice. • Possible applications of EVs as clinical biomarkers (diagnostic, prognostic and evolution marker). • Therapeutic role of EVs being vehicles of specific cargo: current clinical trials? • Novel immunological functions of EVs.

Exosomes and Microvesicles

Author : Andrew F Hill
Publisher : Humana
ISBN 13 : 9781493967261
Total Pages : 0 pages
Book Rating : 4.9/5 (672 download)

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Book Synopsis Exosomes and Microvesicles by : Andrew F Hill

Download or read book Exosomes and Microvesicles written by Andrew F Hill and published by Humana. This book was released on 2016-12-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers methods for the analysis of extracellular vesicles (EV) that can be applied to isolated EVs from a wide variety of sources. This includes the use of electron microscopy, tunable resistance pulse sensing, and nanoparticle tracking analysis. The chapters in this book discuss EV cargoes containing proteins and genomic materials using a number of different approaches, and isolating EVs from platelets and neuronal cells and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Exosomes and Microvesicles: Methods and Protocols is a valuable resource containing methodologies for anyone interested in researching EVs.

Extracellular Vesicles in Human Health and Diseases

Author : Asit Ranjan Ghosh
Publisher : Springer Nature
ISBN 13 : 9819724945
Total Pages : 341 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Extracellular Vesicles in Human Health and Diseases by : Asit Ranjan Ghosh

Download or read book Extracellular Vesicles in Human Health and Diseases written by Asit Ranjan Ghosh and published by Springer Nature. This book was released on with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mesenchymal Stem Cell Derived Exosomes

Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 287 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Phospholipases and Prostaglandins

Author : Claudio Galli
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Phospholipases and Prostaglandins by : Claudio Galli

Download or read book Phospholipases and Prostaglandins written by Claudio Galli and published by Lippincott Williams & Wilkins. This book was released on 1978 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Applications of Extracellular Vesicles

Author : Zhenhua Li
Publisher : John Wiley & Sons
ISBN 13 : 3527842144
Total Pages : 213 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Biomedical Applications of Extracellular Vesicles by : Zhenhua Li

Download or read book Biomedical Applications of Extracellular Vesicles written by Zhenhua Li and published by John Wiley & Sons. This book was released on 2023-11-30 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Extracellular Vesicles Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine Focusing on key points to better understand extracellular vesicles (EVs) and their development, Biomedical Applications of Extracellular Vesicles describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more. The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented. Sample topics covered in Biomedical Applications of Extracellular Vesicles include: Biogenesis of various EVs Pros and cons of the different instrumental and methodological developments for analytical strategies applied to EVs EVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseases Current methods of engineering EVs, and a comparison of the advantages and disadvantages of each method Biomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVs Key challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVs Explaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, Biomedical Applications of Extracellular Vesicles is an essential resource on the subject for chemists, cell biologists, and molecular physicists.

New Horizons in Evolution

Author : Solomon P. Wasser
Publisher : Academic Press
ISBN 13 : 0323907539
Total Pages : 382 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis New Horizons in Evolution by : Solomon P. Wasser

Download or read book New Horizons in Evolution written by Solomon P. Wasser and published by Academic Press. This book was released on 2021-07-30 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Horizons in Evolution is a compendium of the latest research, analyses, and theories of evolutionary biology. Chapters are collected from the international symposium held by the Board of Governors of the University of Haifa to honor Dr. Eviatar Nevo, founder and director of the Institute of Evolution. This book includes material written by top global scientists. Such detailed summaries and recent advances include topics like genomics, epigenetics, evolutionary theory, and the evolution of cancer. This book analyzes evolutionary biology of animals, such as lizards and subterranean mammals. It also discusses agricultural evolution, specifically the vital wheat crop in various climates and locations. Each chapter contributes the most up-to-date knowledge of evolution’s role in speciation, adaptation, and regulation. New Horizons in Evolution is a valuable resource for researchers involved in evolution, evolutionary biology, and evolutionary theory. Advanced undergraduate and graduate students in evolutionary biology courses will also find this useful due to the high expertise level and latest knowledge available through this resource. Examines the evolution of species in extreme conditions Discusses the role of evolution in medicine and cancer research Features the latest data and advances in evolution theory

Fungal Extracellular Vesicles

Author : Marcio Rodrigues
Publisher : Springer Nature
ISBN 13 : 3030833917
Total Pages : 193 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Fungal Extracellular Vesicles by : Marcio Rodrigues

Download or read book Fungal Extracellular Vesicles written by Marcio Rodrigues and published by Springer Nature. This book was released on 2022-01-01 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.

New Insights Into Understanding and Managing NAFLD

Author : Águeda González Rodríguez
Publisher : Frontiers Media SA
ISBN 13 : 288971988X
Total Pages : 223 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis New Insights Into Understanding and Managing NAFLD by : Águeda González Rodríguez

Download or read book New Insights Into Understanding and Managing NAFLD written by Águeda González Rodríguez and published by Frontiers Media SA. This book was released on 2022-01-07 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exosomes in Cardiovascular Diseases

Author : Junjie Xiao
Publisher : Springer
ISBN 13 : 9811043973
Total Pages : 300 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Exosomes in Cardiovascular Diseases by : Junjie Xiao

Download or read book Exosomes in Cardiovascular Diseases written by Junjie Xiao and published by Springer. This book was released on 2017-09-19 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.

The Immunomodulatory Properties of Extracellular Vesicles from Pathogens, Immune Cells and Non-Immune Cells

Author : Ivan K. H. Poon
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis The Immunomodulatory Properties of Extracellular Vesicles from Pathogens, Immune Cells and Non-Immune Cells by : Ivan K. H. Poon

Download or read book The Immunomodulatory Properties of Extracellular Vesicles from Pathogens, Immune Cells and Non-Immune Cells written by Ivan K. H. Poon and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Intercellular and Interorganellar Transfer and Communication in Biology and Medicine

Author : Malgorzata Kloc
Publisher : Springer Nature
ISBN 13 : 3031620364
Total Pages : 572 pages
Book Rating : 4.0/5 (316 download)

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Book Synopsis Intercellular and Interorganellar Transfer and Communication in Biology and Medicine by : Malgorzata Kloc

Download or read book Intercellular and Interorganellar Transfer and Communication in Biology and Medicine written by Malgorzata Kloc and published by Springer Nature. This book was released on with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Possibilities and Limitations in Current Translational Stem Cell Research

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1837680329
Total Pages : 366 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Possibilities and Limitations in Current Translational Stem Cell Research by :

Download or read book Possibilities and Limitations in Current Translational Stem Cell Research written by and published by BoD – Books on Demand. This book was released on 2023-06-21 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the concept of using advanced therapy products such as stem cells seems to be a key strategy in the treatment of various diseases, much information in this area remains unknown. Stem cell products are highly complex, much more complex than chemical-based drugs. More and more often there are data indicating the risk of using stem cells. These risks are determined by various factors that are related to quality, biological activity, and the use itself, and thus administration. Therefore, it is very important to constantly systematize knowledge in this area. This book was created to present both the perspective of basic research, including the manipulation and changes in the properties of cells, and the changes and novelties in therapies themselves.